Assessing the Active Living Impacts of Urban Design Improvements: Brenham TX Main Street Program

Literature search indicates that Main Street Program (MSP) is considered to be successful in achieving the goals of ‘preferred place to live’ and ‘increased active living’. The four point approach of MSP, (organization, promotion, design and economic restructuring) reportedly improves businesses by improving the urban character while allegedly improving active living. This paper focuses on the urban improved areas under the MSP. This research links observable design changes incorporated in the MSP of Brenham TX with identified characteristics of active living. Time constraints prevented collecting sufficient data for a statistically significant study. However a framework is hereby established for future work that more rigorously links MSP and active living for statistical analysis. Preliminary conclusions are drawn based on analysis of the limited available data

An approximate binary-black-hole metric

An approximate solution to Einstein's equations representing two widely-separated non-rotating black holes in a circular orbit is constructed by matching a post-Newtonian metric to two perturbed Schwarzschild metrics. The spacetime metric is presented in a single coordinate system valid up to the apparent horizons of the black holes. This metric could be useful in numerical simulations of binary black holes. Initial data extracted from this metric have the advantages of being linked to the early inspiral phase of the binary system, and of not containing spurious gravitational waves.Comment: 20 pages, 1 figure; some changes in Sec. IV B,C and Sec.

First-order symmetrizable hyperbolic formulations of Einstein's equations including lapse and shift as dynamical fields

First-order hyperbolic systems are promising as a basis for numerical integration of Einstein's equations. In previous work, the lapse and shift have typically not been considered part of the hyperbolic system and have been prescribed independently. This can be expensive computationally, especially if the prescription involves solving elliptic equations. Therefore, including the lapse and shift in the hyperbolic system could be advantageous for numerical work. In this paper, two first-order symmetrizable hyperbolic systems are presented that include the lapse and shift as dynamical fields and have only physical characteristic speeds.Comment: 11 page

Transition metal oxide nanopowder and ionic liquid: an efficient system for the synthesis of diorganyl selenides, selenocysteine and derivatives

We have developed an efficient method for the synthesis of diorganyl selenides and β-seleno amines using Zn, catalytic amounts of ZnO nanopowder, as a catalyst and ionic liquid as a recyclable solvent. This ZnO/ionic liquid system shows high efficiency in catalyzing these transformations with the formation of the desired products in high yields

Drug overdose: a wake up call! Experience at a tertiary care centre in Karachi, Pakistan

OBJECTIVE: To study the characteristics of patients admitted with drug overdose caused either by accidental overdose of the prescribed medications or as an act of deliberate self harm (DSH) at a tertiary care hospital in Karachi, Pakistan.METHODS: A retrospective case series review was conducted at the Aga Khan University Hospital from January 2002 to October 2006. Three hundred and twenty four adult patients admitted with drug overdose were included in the study.RESULTS: Our sample group revealed mean age of 36.2 +/- 17.0 years, more females (59%), housewives (34%), and students (20%). Fifty six percent of patients committing DSH were married (p = 0.001), 81% needed in-patient psychiatric services (p = 0.016) of whom a significantly high number (38%) refused it. Domestic and social issues were rated highest among DSH group (p = 0.003), depression among females was common (p = 0.028) and Benzodiazepines (41%) was the most frequently used drug (p = 0.021). Sub-group analysis of accidental overdoses revealed mean age of 45.6 +/- 19.6 years, single (75.4%) and males (54.1%). Drugs used were mainly Benzodiazepines (18%) followed by Opioids (11%), Antiepileptics (10%) and Warfarin (10%).CONCLUSION: Our study showed that depressed housewives are at greater risk for DSH. Domestic and social issues were rated highest and Benzodiazepines were the most commonly used agents. Most of our patients refused inpatient psychiatric treatment leading us to believe that general awareness of psychiatric illnesses is imperative in our community. High number of accidental overdoses is alarming in older, single males convincing us to believe that existing pharmacy system needs further evaluation and modification

A Bayesian non-linear method for feature selection in machine translation quality estimation

We perform a systematic analysis of the effectiveness of features for the problem of predicting the quality of machine translation (MT) at the sentence level. Starting from a comprehensive feature set, we apply a technique based on Gaussian processes, a Bayesian non-linear learning method, to automatically identify features leading to accurate model performance. We consider application to several datasets across different language pairs and text domains, with translations produced by various MT systems and scored for quality according to different evaluation criteria. We show that selecting features with this technique leads to significantly better performance in most datasets, as compared to using the complete feature sets or a state-of-the-art feature selection approach. In addition, we identify a small set of features which seem to perform well across most datasets

An electrochemical DNA biosensor based gold-thiolate conjugation utilizing ruthenium complex [Ru(dppz)2(qtpy)]Cl2

Non toxicity and high isoelectric point of zinc oxide nanorods (ZnO NRs) are the promising materials widely used in biomolecule detection and biomedicine application. An electrochemical DNA biosensor was successfully fabricated by depositing (3-Aminopropyl)triethoxysilane and gold nanoparticles (GNPs) on the hydrothermal growth ZnO NRs. The modified surface with GNPs (35 ± 5 nm) was characterized by field emission scanning electron microscopy with energy dispersive X-ray and X-ray diffraction. The fabricated electrode was used for the label-free detection of DNA. Thiolated (–SH) single stranded DNA was immobilized onto the GNPs surface to form a gold-thiolate bond. Hybridization with complementary target DNA was performed with the presence of ruthenium complex. Immobilization and hybridization detection were performed using µAUTOLAB with cyclic voltammetric software. The measured sensitivity of the fabricated electrode for hybridization is up to 1.6 times larger than immobilization

Intracranial chordoma presenting as acute hemorrhage in a child: Case report and literature review

BACKGROUND: Chordomas are rare, slow-growing malignant neoplasms derived from remnants of the embryological notochord. Pediatric cases comprise only 5% of all chordomas, but more than half of the reported pediatric chordomas are intracranial. For patients of all ages, intracranial chordomas typically present with symptoms such as headaches and progressive neurological deficits occurring over several weeks to many years as they compress or invade local structures. There are only reports of these tumors presenting acutely with intracranial hemorrhage in adult patients. CASE DESCRIPTION: A 10-year-old boy presented with acute onset of headache, emesis, and diplopia. Head computed tomography and magnetic resonance imaging of brain were suspicious for a hemorrhagic mass located in the left petroclival region, compressing the ventral pons. The mass was surgically resected and demonstrated acute intratumoral hemorrhage. Pathologic examination was consistent with chordoma. CONCLUSION: There are few previous reports of petroclival chordomas causing acute intracranial hemorrhage. To the authors' knowledge, this is the first case of a petroclival chordoma presenting as acute intracranial hemorrhage in a pediatric patient. Although uncommon, it is important to consider chordoma when evaluating a patient of any age presenting with a hemorrhagic lesion of the clivus