5 research outputs found
How Accurate Is the Prediction of Maximal Oxygen Uptake with Treadmill Testing?
<div><p>Background</p><p>Cardiorespiratory fitness measured by treadmill testing has prognostic significance in determining mortality with cardiovascular and other chronic disease states. The accuracy of a recently developed method for estimating maximal oxygen uptake (VO<sub>2peak</sub>), the heart rate index (HRI), is dependent only on heart rate (HR) and was tested against oxygen uptake (VO<sub>2</sub>), either measured or predicted from conventional treadmill parameters (speed, incline, protocol time).</p><p>Methods</p><p>The HRI equation, METs = 6 x HRI– 5, where HRI = maximal HR/resting HR, provides a surrogate measure of VO<sub>2peak</sub>. Forty large scale treadmill studies were identified through a systematic search using MEDLINE, Google Scholar and Web of Science in which VO<sub>2peak</sub> was either measured (TM-VO<sub>2meas</sub>; n = 20) or predicted (TM-VO<sub>2pred</sub>; n = 20) based on treadmill parameters. All studies were required to have reported group mean data of both resting and maximal HRs for determination of HR index-derived oxygen uptake (HRI-VO<sub>2</sub>).</p><p>Results</p><p>The 20 studies with measured VO<sub>2</sub> (TM-VO<sub>2meas</sub>), involved 11,477 participants (median 337) with a total of 105,044 participants (median 3,736) in the 20 studies with predicted VO<sub>2</sub> (TM-VO<sub>2pred</sub>). A difference of only 0.4% was seen between mean (±SD) VO<sub>2peak</sub> for TM- VO<sub>2meas</sub> and HRI-VO<sub>2</sub> (6.51±2.25 METs and 6.54±2.28, respectively; p = 0.84). In contrast, there was a highly significant 21.1% difference between mean (±SD) TM-VO<sub>2pred</sub> and HRI-VO<sub>2</sub> (8.12±1.85 METs and 6.71±1.92, respectively; p<0.001).</p><p>Conclusion</p><p>Although mean TM-VO<sub>2meas</sub> and HRI-VO<sub>2</sub> were almost identical, mean TM-VO<sub>2pred</sub> was more than 20% greater than mean HRI-VO<sub>2</sub>.</p></div
Heart rate and oxygen consumption data for TM-VO<sub>2meas</sub> and TM-VO<sub>2pred</sub>.
<p>Group mean (± 1SD) heart rate (HR) and oxygen consumption (VO<sub>2</sub>) data. HR<sub>rest</sub>, HR<sub>peak</sub>, HRI-VO<sub>2</sub> and VO<sub>2peak</sub> for TM-VO<sub>2meas</sub> and TM-VO<sub>2pred</sub>.</p
Comparison of pooled data from 20 studies for TM-VO<sub>2meas</sub> and TM-VO<sub>2pred</sub> against HRI-VO<sub>2</sub>.
<p>A. Comparison of group mean data for 20 TM-VO<sub>2meas</sub> and TM-VO<sub>2pred</sub> studies against HRI-VO2 (mean ± SE), B. Comparison of cardiorespiratory fitness tertiles from 20 studies for TM-VO<sub>2meas</sub> against HRI-VO<sub>2</sub> (mean ±SE). Percentage difference between TM-VO<sub>2meas</sub> and HRI-VO<sub>2</sub> shown within figure and C. Comparison of cardiorespiratory fitness tertiles from 20 studies for TM-VO<sub>2pred</sub> against HRI-VO<sub>2</sub> (mean ±SE). Percentage difference between TM-VO<sub>2pred</sub> and HRI-VO<sub>2</sub> shown within figure.</p
Line of identity and Bland Altman plot for TM-VO<sub>2meas</sub>.
<p>A. Line of identity for TM-VO<sub>2meas</sub> and B. against Bland Altman plot for TM-VO<sub>2meas</sub> against HRI-VO<sub>2</sub>.</p
Line of identity and Bland Altman plot for TM-VO<sub>2pred</sub>.
<p><b>A.</b> Line of identity for TM-VO<sub>2pred</sub> and B. against Bland Altman plot for TM-VO<sub>2pred</sub> against HRI-VO<sub>2</sub>.</p