11,239 research outputs found

    Improving the quality of assessment and management of hypoglycaemia in hospitalised patients with diabetes mellitus by introducing 'hypo boxes' to general medical wards with a specialist interest in diabetes

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    Diabetes is becoming more prevalent in the UK and this is represented in the in-patient cohort, such that 1 in 6 hospital patients have diabetes (1). The UK National Diabetes In-Patient Audit in 2012 estimated that 30% of patients experience one episode of hypoglycaemia during admission. Hypoglycaemia is associated with increased morbidity and mortality, and longer length of hospital stay. It is therefore important that hypoglycaemia is managed promptly and effectively to reduce associated morbidity. The Joint British Diabetes Society recommends that all wards should have access to ‘Hypo Boxes’ (2). We assessed all episodes of hypoglycaemia (<4.0 mmol/l) in the diabetes wards in over a 4 week period. ‘Hypo Boxes’ were installed to the wards and the appropriateness of treatment and time to correction of hypoglycaemia was re-assessed. Assessment of hypoglycaemia pre-intervention revealed 45 episodes of hypoglycaemia in 14 patients, and 42% (n=19) of episodes were deemed to have been treated appropriately. Only 17.8% of episodes were corrected within 30 minutes, and 33.3% were corrected within 60 minutes. A third of patients (35%) did not have a further blood glucose checked. Following intervention, there was a marked improvement in management. The proportion of appropriately managed episodes increased to 82% (n=35) and management of episodes of severe hypoglycaemia (<3.0 mmol/l) increased to 94%. The time to correction increased with 40% of episodes corrected to >4.0 mmol/l within 30 minutes, and a further 54% between 30-60 minutes. In conclusion, the introduction of ‘Hypo Boxes’ improved the assessment and management of hypoglycaemia

    Hermitian and skew hermitian forms over local rings

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    We study the classification problem of possibly degenerate hermitian and skew hermitian bilinear forms over local rings where 2 is a unit

    Unbound Star-forming Molecular Clouds

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    We explore whether observed molecular clouds could include a substantial population of unbound clouds. Using simulations which include only turbulence and gravity, we are able to match observed relations and naturally reproduce the observed scatter in the cloud size-linewidth coefficient, at fixed surface density. We identify the source of this scatter as a spread in the intrinsic virial parameter. Thus these observational trends do not require that clouds exist in a state of dynamical equilibrium. We demonstrate that cloud virial parameters can be accurately determined observationally with an appropriate size estimator. All our simulated clouds eventually form collapsing cores, regardless of whether the cloud is bound overall. This supports the idea that molecular clouds do not have to be bound to form stars or to have observed properties like those of nearby low-mass clouds.Comment: 9 pages, 6 figures, Accepted for publication by MNRA

    Evolving Molecular Cloud Structure and the Column Density Probability Distribution Function

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    The structure of molecular clouds can be characterized with the probability distribution function (PDF) of the mass surface density. In particular, the properties of the distribution can reveal the nature of the turbulence and star formation present inside the molecular cloud. In this paper, we explore how these structural characteristics evolve with time and also how they relate to various cloud properties as measured from a sample of synthetic column density maps of molecular clouds. We find that, as a cloud evolves, the peak of its column density PDF will shift to surface densities below the observational threshold for detection, resulting in an underlying lognormal distribution which has been effectively lost at late times. Our results explain why certain observations of actively star-forming, dynamically older clouds, such as the Orion molecular cloud, do not appear to have any evidence of a lognormal distribution in their column density PDFs. We also study the evolution of the slope and deviation point of the power-law tails for our sample of simulated clouds and show that both properties trend towards constant values, thus linking the column density structure of the molecular cloud to the surface density threshold for star formation.Comment: 10 pages, 9 figures, Accepted for publication by MNRA
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