Perception and practice of self-medication with over-the-counter analgesics among students of a tertiary institution

Background: Although over-the-counter (OTC) analgesics increase access to and ease of medication, they are a major contributor to irrational use of medicines worldwide.This study assessed perception and practice of self-medication with OTC analgesics among students of Federal College of Education,Zaria.Method: It was a cross-sectional study of 200 students. Data was collected using a self-administered questionnaire. Descriptive statistics were computed, and Chi-square test was used to test association between practice of self-medication and other categorical variables.Results: Seventy-six (38.8%) had good knowledge of OTC analgesics and 187 (95.4%) had good perception. Majority 151 (77.0%) had taken at least one OTC analgesic in the last three months.The most common reason for taking OTC analgesics was their easy availability 66 (43.7%),and the most common symptom treated was headache 80 (53.0%).Self-medication with OTC analgesics was significantly associated with age (p = 0.010) and level of study (p = 0.001),but not with sex (p = 0.866),ethnicity (p = 0.416) or marital status (p = 0.104).Conclusion: Knowledge of OTC analgesics was poor,perception was largely positive,while self-medication was a common practice. Major factors influencing self-medication were age and level of education. It is recommended that efforts to control excessive self-medication with OTC analgesics should focus on creating public awareness and restricting the sale of OTC analgesics to licensed dealers.Keywords: Self-Medication, Over-The-Counter, Analgesics,Student

The Moderating Role of Innovativeness on the Relationship between Entrepreneurship Educations And Student Entrepreneurial Intention

This study examined the moderating role of innovativeness on the relationship between entrepreneurship education and students' entrepreneurial intention among FUD final year students as at 2017/2018 academic session. The study used a cross-sectional research design with a quantitative questionnaire approach to collect the data. To validate the model, data from 282 final year students were analyzed using the Partial Least Squares Structural Equation Modelling (PLS-SEM). Overall, the survey discovered that both entrepreneurship education and innovativeness are significantly and positively connected to entrepreneurial intention. This report also discovered that innovativeness play a part in moderating the entrepreneurship education and entrepreneurial intention relationship. The study used Human Capital Theory HCT as a theoretical basis of the subject. This survey served as one of the pioneering study with regard to HCT in a testing relationship of this nature. This study recommended that other researchers should employ this hypothesis with other antecedent of entrepreneurial intention for further proof. As a repercussion to policy, the government ought to guarantee not only inspiring students with entrepreneurship education, but also the robust spirit of innovativeness among students as it delivers a direct effect as well as strong interaction with entrepreneurship education in influencing students' entrepreneurial intention

Relationship between Housing Condition, Soldiers' Social Life and Morale in Coral Barracks, Nigeria

Despite the numerous empirical studies that have been conducted on housing conditions, there is still very little research work carried out on military barracks life, the impact of the condition of the barracks' accommodation on the soldiers' social life and morale. Thus, this paper presents a study on the relationship between housing conditions, soldiers' social life, and morale in Coral Barracks Nigeria and covers only the non-commissioned officers' quarters. A quantitative method using a questionnaire survey was used with a sample size of 260. The data were analysed using descriptive statistics as well as parametric measurements. A total number of 194 questionnaires retrieved from the respondents were used in the analyses. Building services attributes had a strong and significant positive correlation. Moreover, neighbourhood and soldiers' life correlate significantly, negative but weak, while physical housing attributes and neighbourhood attributes correlate significantly but negatively and weak with children's life. Neighbourhood attributes and soldiers' morale recorded a significant, negative but weak correlation. In light of these findings, this study recommends that a standard strategic plan for efficient barrack housing construction, management, and maintenance is designed

Knowledge, Perception, and Consumption of Food Additives among Female Lecturers in Zaria, Nigeria

Background: Food additives are being utilized for both small‑ and large‑scale food production but often find more applicability in mass food production. Food additive consumption over a long period could pose adverse health outcomes. The study determined knowledge, perception, and consumption of food additives among female lecturers in Zaria. Methodology: It was a cross‑sectional study conducted among 180 full‑time female lecturers of the three tertiary institutions, selected through a multistage sampling technique. Data were collected using a pretested self‑administered questionnaire. The data were entered into IBM SPSS Statistics 20 and analyzed. Univariate analysis for categorical variables was done using simple proportions. Results: A total of 167 female lecturers responded giving a response rate of 92.8%. Their mean age was 42.7 ± 8.2 years. Majority (109, 65.3%) had good knowledge of food additives, less than half (77, 46.3%) had a good perception of them, and the overall consumption rate for food additives was 97.1%. Majority (77.8%) felt that the risks associated with food additives must never be ignored, about half (47.3%) felt that foods consumed by Nigerians were now generally more harmful. However, only about one‑fifth felt that most fast foods do contain food additives (28.1%). Consumption rates were high for both natural and synthetic food additives (61.7%–92.2%), except for Ajinomoto and Vedan which were consumed by only 38 (22.8%). Conclusion: Knowledge of food additives was good, but their perception was poor and consumption was high. Stakeholders must begin to organize and sustain periodic sensitization campaigns on risks associated with the consumption of food additives. Futures studies should identify the reasons for poor perception and high level of consumption despite good knowledge among the study population. Keywords: Consumption, female lecturers, food additives, Zari

Pattern of Cancer in Bauchi: Report from a Departmental Cancer Registry

Context: Cancer ranks second among the major causes of death globally. A projection by 2020 indicated that developing countries wouldaccount for about 70% of total cancer‑related death worldwide. Despite the great threat posed by cancer to this region of the world,  reliable statistics on the trends and patterns of cancer are rare. Aims: The aim of the study is to review the cases of cancer recorded in Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH), Bauchi, from January 1, 2011 to December 31, 2019 Materials and Methods: This is a retrospective, descriptive study. Nine years records of all pathologically diagnosed cancer cases in the ATBUTH, Bauchi were retrieved, reviewed, and grouped in accordance with the International Classification of Diseases for Oncology. The results were presented as simple frequency tables and charts. Results: A total of 1284 cancer cases were diagnosed during the period, an average of 142.7 cases per annum. There was a female predominance of cancer cases (male: female ratio ‑ 1:1.53. The age range was from seven months to 95 years, with mean and medianages of 49.6 and 50 years, respectively. More than half of the cases were reported in the fifth to seventh decades of life. Prostate (14.6%)and non melanoma skin cancer (11.2%) were the most common cancers seen in males. In females, cancers of the cervix (37.9%) and thebreast (22.9%) were the most common. Conclusions: Breast cancer and cancer of the uterine cervix were the most common cancers in women in this review while prostate cancer was the most common cancer in men. The need to establish a hospital‑based and/or population‑based cancer registry that will generate reliable cancer data in our environment cannot be overemphasized. Keywords: Bauchi, breast, cancer, cervix, prostate, registr

Epidemiology of COVID-19 and Predictors of Outcome in Nigeria: A Single-Center Study.

There is a paucity of information regarding the epidemiology and outcome of COVID-19 from low/middle-income countries, including from Nigeria. This single-center study described the clinical features, laboratory findings, and predictors of in-hospital mortality of COVID-19 patients. Patients admitted between April 10, 2020 and June 10, 2020 were included. Forty-five patients with a mean age of 43 (16) years, predominantly male (87%), presented with fever (38%), cough (29%), or dyspnea (24%). In-hospital mortality was 16%. The independent predictors of mortality were hypoxemia (adjusted odds ratio [aOR]: 2.5; 95% CI: 1.3-5.1) and creatinine \u3e 1.5 mg/dL (aOR: 4.3; 95% CI: 1.9-9.8)

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension

Aims Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those with hypertension are aware of it. May Measurement Month (MMM) is a global campaign set up in 2017, to raise awareness of high BP and as a pragmatic solution to a lack of formal screening worldwide. The 2018 campaign was expanded, aiming to include more participants and countries. Methods and results Eighty-nine countries participated in MMM 2018. Volunteers (≥18 years) were recruited through opportunistic sampling at a variety of screening sites. Each participant had three BP measurements and completed a questionnaire on demographic, lifestyle, and environmental factors. Hypertension was defined as a systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or taking antihypertensive medication. In total, 74.9% of screenees provided three BP readings. Multiple imputation using chained equations was used to impute missing readings. 1 504 963 individuals (mean age 45.3 years; 52.4% female) were screened. After multiple imputation, 502 079 (33.4%) individuals had hypertension, of whom 59.5% were aware of their diagnosis and 55.3% were taking antihypertensive medication. Of those on medication, 60.0% were controlled and of all hypertensives, 33.2% were controlled. We detected 224 285 individuals with untreated hypertension and 111 214 individuals with inadequately treated (systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg) hypertension. Conclusion May Measurement Month expanded significantly compared with 2017, including more participants in more countries. The campaign identified over 335 000 adults with untreated or inadequately treated hypertension. In the absence of systematic screening programmes, MMM was effective at raising awareness at least among these individuals at risk

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication