Husserl, Dummett, and the linguistic turn

Michael Dummett famously holds that the “philosophy of thought” must proceed via the philosophy of language, since that is the only way to preserve the objectivity of thoughts while avoiding commitments to “mythological,” Platonic entities. Central to Dummett’s case is his thesis that all thought contents are linguistically expressible. In this paper, I will (a) argue that making the linguistic turn is neither necessary nor sufficient to avoid the problems of psychologism, (b) discuss Wayne Martin’s argument that not all thought-contents are linguistically communicable, and (c) present another, stronger argument, derived from Husserl’s early account of fulfillment, that establishes the same conclusion

Efficient KEX2-like processing of a glucoamylase-interleukin-6 fusion protein by Aspergillus nidulans and secretion of mature interleukin-6

We have designed an expression vector for the secretion of human interleukin-6 (hIL-6) in which the mature protein is fused through a spacer peptide, containing a KEX-2 like protein processing signal, to the entire Aspergillus niger glucoamylase (glaA) gene. Transformation of Aspergillus nidulans with this vector results in fungal strains secreting equimolar amounts of the glucoamylase and IL-6 proteins. The KEX2-type processing signal, Lys-Arg, is recognized and cleaved efficiently by an enzyme present in A. nidulans resulting in the secretion of an authentic mature hIL-6 protein at levels of up to 5 mg/l