1,480 research outputs found
The Recent Rise of Southern Banking
Between 1984 and 1986 the legislatures of several southern states enacted changes to their banking laws that enabled banking companies in Southern Region states to acquire and be acquired by banking companies in other Southern Region states, as long as these companies qualified as âSouthern.â The purpose of the compact was to allow some southern banking companies an opportunity to grow and gain financial strength before full interstate banking was permitted. This study shows that the compact was successful. In 1985 no southern banking companies were among the top ten banks in the country, but by 2005 four were. Furthermore, no major southern bank has been acquired by a U.S. banking company outside of the South, although several southern banking companies have bought banks in other regions. The southern economy and its banking industry have benefited, although the benefits have been unevenly spread among states
UAV mapping of rhizoctonia bare patch for targeted treatment
Rhizoctonia patches can be easily identified on both normal (RGB) and NDVI images captured by UAV. Mapping shows the pattern of patch distribution across a paddock, highlighting areas of crop with high and low levels of rhizoctonia patches
Adaptive LĂŠvy processes and area-restricted search in human foraging
A considerable amount of research has claimed that animalsâ foraging behaviors display movement lengths with power-law distributed tails, characteristic of LĂŠvy flights and LĂŠvy walks. Though these claims have recently come into question, the proposal that many animals forage using LĂŠvy processes nonetheless remains. A LĂŠvy process does not consider when or where resources are encountered, and samples movement lengths independently of past experience. However, LĂŠvy processes too have come into question based on the observation that in patchy resource environments resource-sensitive foraging strategies, like area-restricted search, perform better than LĂŠvy flights yet can still generate heavy-tailed distributions of movement lengths. To investigate these questions further, we tracked humans as they searched for hidden resources in an open-field virtual environment, with either patchy or dispersed resource distributions. Supporting previous research, for both conditions logarithmic binning methods were consistent with LĂŠvy flights and rank-frequency methodsâcomparing alternative distributions using maximum likelihood methodsâshowed the strongest support for bounded power-law distributions (truncated LĂŠvy flights). However, goodness-of-fit tests found that even bounded power-law distributions only accurately characterized movement behavior for 4 (out of 32) participants. Moreover, paths in the patchy environment (but not the dispersed environment) showed a transition to intensive search following resource encounters, characteristic of area-restricted search. Transferring paths between environments revealed that paths generated in the patchy environment were adapted to that environment. Our results suggest that though power-law distributions do not accurately reflect human search, LĂŠvy processes may still describe movement in dispersed environments, but not in patchy environmentsâwhere search was area-restricted. Furthermore, our results indicate that search strategies cannot be inferred without knowing how organisms respond to resourcesâas both patched and dispersed conditions led to similar LĂŠvy-like movement distributions
A randomized assessment of adding the kinase inhibitor lestaurtinib to first-line chemotherapy for FLT3-mutated AML
The clinical benefit of adding FMS-like tyrosine kinase-3 (FLT3)-directed small molecule therapy to standard first-line treatment of acute myeloid leukemia (AML) has not yet been established. As part of the UK AML15 and AML17 trials, patients with previously untreated AML and confirmed FLT3-activating mutations, mostly younger than 60 years, were randomly assigned either to receive oral lestaurtinib (CEP701) or not after each of 4 cycles of induction and consolidation chemotherapy. Lestaurtinib was commenced 2 days after completing chemotherapy and administered in cycles of up to 28 days. The trials ran consecutively. Primary endpoints were overall survival in AML15 and relapse-free survival in AML17; outcome data were meta-analyzed. Five hundred patients were randomly assigned between lestaurtinib and control: 74% had FLT3-internal tandem duplication mutations, 23% FLT3âtyrosine kinase domain point mutations, and 2% both types. No significant differences were seen in either 5-year overall survival (lestaurtinib 46% vs control 45%; hazard ratio, 0.90; 95% CI 0.70-1.15; P = .3) or 5-year relapse-free survival (40% vs 36%; hazard ratio, 0.88; 95% CI 0.69-1.12; P = .3). Exploratory subgroup analysis suggested survival benefit with lestaurtinib in patients receiving concomitant azole antifungal prophylaxis and gemtuzumab ozogamicin with the first course of chemotherapy. Correlative studies included analysis of in vivo FLT3 inhibition by plasma inhibitory activity assay and indicated improved overall survival and significantly reduced rates of relapse in lestaurtinib-treated patients who achieved sustained greater than 85% FLT3 inhibition. In conclusion, combining lestaurtinib with intensive chemotherapy proved feasible in younger patients with newly diagnosed FLT3-mutated AML, but yielded no overall clinical benefit. The improved clinical outcomes seen in patients achieving sustained FLT3 inhibition encourage continued evaluation of FLT3-directed therapy alongside front-line AML treatment. The UK AML15 and AML17 trials are registered at www.isrctn.com/ISRCTN17161961 and www.isrctn.com/ISRCTN55675535 respectively
A Derivation of Three-Dimensional Inertial Transformations
The derivation of the transformations between inertial frames made by
Mansouri and Sexl is generalised to three dimensions for an arbitrary direction
of the velocity. Assuming lenght contraction and time dilation to have their
relativistic values, a set of transformations kinematically equivalent to
special relativity is obtained. The ``clock hypothesis'' allows the derivation
to be extended to accelerated systems. A theory of inertial transformations
maintaining an absolute simultaneity is shown to be the only one logically
consistent with accelerated movements. Algebraic properties of these
transformations are discussed. Keywords: special relativity, synchronization,
one-way velocity of light, ether, clock hypothesis.Comment: 16 pages (A5), Latex, one figure, to be published in Found. Phys.
Lett. (1997
CCAT-prime: a novel telescope for submillimeter astronomy
The CCAT-prime telescope is a 6-meter aperture, crossed-Dragone telescope,
designed for millimeter and sub-millimeter wavelength observations. It will be
located at an altitude of 5600 meters, just below the summit of Cerro
Chajnantor in the high Atacama region of Chile. The telescope's unobscured
optics deliver a field of view of almost 8 degrees over a large, flat focal
plane, enabling it to accommodate current and future instrumentation fielding
>100k diffraction-limited beams for wavelengths less than a millimeter. The
mount is a novel design with the aluminum-tiled mirrors nested inside the
telescope structure. The elevation housing has an integrated shutter that can
enclose the mirrors, protecting them from inclement weather. The telescope is
designed to co-host multiple instruments over its nominal 15 year lifetime. It
will be operated remotely, requiring minimum maintenance and on-site activities
due to the harsh working conditions on the mountain. The design utilizes
nickel-iron alloy (Invar) and carbon-fiber-reinforced polymer (CFRP) materials
in the mirror support structure, achieving a relatively temperature-insensitive
mount. We discuss requirements, specifications, critical design elements, and
the expected performance of the CCAT-prime telescope. The telescope is being
built by CCAT Observatory, Inc., a corporation formed by an international
partnership of universities. More information about CCAT and the CCAT-prime
telescope can be found at www.ccatobservatory.org.Comment: Event: SPIE Astronomical Telescope + Instrumentation, 2018, Austin,
Texas, USA; Proceedings Volume 10700, Ground-based and Airborne Telescopes
VII; 107005X (2018
The political process of constructing a sustainable London Olympics sports development legacy
This study attempts to develop a research agenda for understanding the process of constructing a sustainable Olympic sports development legacy. The research uses a social constructivist perspective to examine the link between the 2012 London Olympic Games and sustainable sports development. The first part of the paper provides justification for the study of sport policy processes using a constructivist lens. This is followed by a section which critically unpacks sustainable sports development drawing on Mosseâs (1998) ideas of process-oriented research and Searleâs conceptualisation of the construction of social reality. Searleâs (1995) concepts of the assignment of function, collective intentionality, collective rules, and human capacity to cope with the environment are considered in relation to the events and discourses emerging from the legacy vision(s) associated with the 2012 London Olympic Games. The paper concludes by proposing a framework for engaging in process oriented research and highlights key elements, research questions, and methodological issues. The proposed constructivist approach can be used to inform policy, practice, and research on sustainable Olympic sports development legacy
Atmospheric Acetaldehyde: Importance of Air-Sea Exchange and a Missing Source in the Remote Troposphere.
We report airborne measurements of acetaldehyde (CH3CHO) during the first and second deployments of the National Aeronautics and Space Administration (NASA) Atmospheric Tomography Mission (ATom). The budget of CH3CHO is examined using the Community Atmospheric Model with chemistry (CAM-chem), with a newly-developed online air-sea exchange module. The upper limit of the global ocean net emission of CH3CHO is estimated to be 34 Tg a-1 (42 Tg a-1 if considering bubble-mediated transfer), and the ocean impacts on tropospheric CH3CHO are mostly confined to the marine boundary layer. Our analysis suggests that there is an unaccounted CH3CHO source in the remote troposphere and that organic aerosols can only provide a fraction of this missing source. We propose that peroxyacetic acid (PAA) is an ideal indicator of the rapid CH3CHO production in the remote troposphere. The higher-than-expected CH3CHO measurements represent a missing sink of hydroxyl radicals (and halogen radical) in current chemistry-climate models
Confirmatory Factor Analysis of Warr, Cook, and Wall's (1979) Job Satisfaction Scale
Warr, Cook, and Wall's Job Satisfaction Scale (JSS) is a widely used measure of job satisfaction in industrial/organisational (I/O) psychology research and practice. However, the factor structure has not been adequately explored, with two-factor and three-factor solutions previously proposed. This study tested the factor structure of the JSS using robust analysis methods on data gathered from a convenience sample of 381 (females=264, males=116) Australian employees. Confirmatory factor analyses supported a hierarchical three-factor model of job satisfaction in terms of model adequacy coefficients; however, the three factors were highly correlated, thereby rendering a multifactorial approach to the JSS untenable. The results support the continued use of an overall score of job satisfaction when using this measure in I/O psychology research and practice. Further testing of the structure is recommended within a range of employment sectors, as the assumed multifactorial structure of the JSS common in the literature was not supported by the current study
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