Negative and Nonlinear Response in an Exactly Solved Dynamical Model of Particle Transport

We consider a simple model of particle transport on the line defined by a dynamical map F satisfying F(x+1) = 1 + F(x) for all x in R and F(x) = ax + b for |x| < 0.5. Its two parameters a (`slope') and b (`bias') are respectively symmetric and antisymmetric under reflection x -> R(x) = -x. Restricting ourselves to the chaotic regime |a| > 1 and therein mainly to the part a>1 we study not only the `diffusion coefficient' D(a,b), but also the `current' J(a,b). An important tool for such a study are the exact expressions for J and D as obtained recently by one of the authors. These expressions allow for a quite efficient numerical implementation, which is important, because the functions encountered typically have a fractal character. The main results are presented in several plots of these functions J(a,b) and D(a,b) and in an over-all `chart' displaying, in the parameter plane, all possibly relevant information on the system including, e.g., the dynamical phase diagram as well as invariants such as the values of topological invariants (kneading numbers) which, according to the formulas, determine the singularity structure of J and D. Our most significant findings are: 1) `Nonlinear Response': The parameter dependence of these transport properties is, throughout the `ergodic' part of the parameter plane (i.e. outside the infinitely many Arnol'd tongues) fractally nonlinear. 2) `Negative Response': Inside certain regions with an apparently fractal boundary the current J and the bias b have opposite signs.Comment: corrected typos and minor reformulations; 28 pages (revtex) with 7 figures (postscript); accepted for publication in JS

Literature review on pickling inhibitors and cadmium electroplating processes

Because introduction of hydrogen during bright-cadmium electroplating of high strength steels causes hydrogen-stress cracking, a program was undertaken to evaluate various processes and materials. Report describes effectiveness of inhibitors for reducing hydrogen absorption by steels

A review of the literature on cleaning, pickling, and electroplating processes and relief treatments to minimize hydrogen embrittlement of ultrahigh-strength steels Special report

Cleaning, pickling, and electroplating processes to minimize hydrogen embrittlement of ultrahigh strength steel

A review of the literature on pickling inhibitors and cadmium electroplating processes to minimize hydrogen absorption by ultrahigh-strength steels

Literature review on pickling inhibitors and cadmium electroplating processes to minimize hydrogen absorption by ultrahigh strength steel

A study of hydrogen embrittlement of various alloys Annual summary report, 24 Jun. 1965 - 23 Jun. 1966

Hydrogen embrittlement of alloy cathodically charged and notched tensile metal

Review of literature on hydrogen embrittlement

Hydrogen embrittlement in high strength iron-base and nickel-base alloys and titaniu

Global end-diastolic volume increases to maintain fluid responsiveness in sepsis-induced systolic dysfunction

Background: Sepsis-induced cardiac dysfunction may limit fluid responsiveness and the mechanism thereof remains unclear. Since cardiac function may affect the relative value of cardiac filling pressures, such as the recommended central venous pressure (CVP), versus filling volumes in guiding fluid loading, we studied these parameters as determinants of fluid responsiveness, according to cardiac function.Methods: A delta CVP-guided, 90 min colloid fluid loading protocol was performed in 16 mechanically ventilated patients with sepsis-induced hypotension and three 30 min consecutive fluid loading steps of about 450 mL per patient were evaluated. Global end-diastolic volume index (GEDVI), cardiac index (CI) and global ejection fraction (GEF) were assessed from transpulmonary dilution. Baseline and changes in CVP and GEDVI were compared among responding (CI increase ≥10% and ≥15%) and non-responding fluid loading steps, in patient with low (<20%, n = 9) and near-normal (≥20%) GEF (n = 7) at baseline.Results: A low GEF was in line with other indices of impaired cardiac (left ventricular) function, prior to and after fluid loading. Of 48 fluid loading steps, 9 (of 27) were responding when GEF <20% and 6 (of 21) when GEF ≥20. Prior to fluid loading, CVP did not differ between responding and non-responding steps and levels attained were 23 higher in the latter, regardless of GEF (P = 0.004). Prior to fluid loading, GEDVI (and CI) was higher in responding (1007 ± 306 mL/m2) than non-responding steps (870 ± 236 mL/m2) when GEF was low (P = 0.002), but did not differ when GEF was near-normal. Increases in GEDVI were associated with increases in CI and fluid responsiveness, regardless of GEF (P < 0.001).Conclusions: As estimated from transpulmonary dilution, about half of patients with sepsis-induced hypotension have systolic cardiac dysfunction. During dysfunction, cardiac dilation with a relatively high baseline GEDVI maintains fluid responsiveness by further dilatation (increase in GEDVI rather than of CVP) as in patients without dysfunction. Absence of fluid responsiveness during systolic cardiac dysfunction may be caused by diastolic dysfunction and/or right ventricular dysfunction

Detection and mapping of illicit drugs and their metabolites in fingermarks by MALDI MS and compatibility with forensic techniques

Despite the proven capabilities of Matrix Assisted Laser Desorption Ionisation Mass Spectrometry (MALDI MS) in laboratory settings, research is still needed to integrate this technique into current forensic fingerprinting practice. Optimised protocols enabling the compatible application of MALDI to developed fingermarks will allow additional intelligence to be gathered around a suspect’s lifestyle and activities prior to the deposition of their fingermarks while committing a crime. The detection and mapping of illicit drugs and metabolites in latent fingermarks would provide intelligence that is beneficial for both police investigations and court cases. This study investigated MALDI MS detection and mapping capabilities for a large range of drugs of abuse and their metabolites in fingermarks; the detection and mapping of a mixture of these drugs in marks, with and without prior development with cyanoacrylate fuming or Vacuum Metal Deposition, was also examined. Our findings indicate the versatility of MALDI technology and its ability to retrieve chemical intelligence either by detecting the compounds investigated or by using their ion signals to reconstruct 2D maps of fingermark ridge details