Assessing Renewable Technologies at Wild Mountain Cooperative

This report is a renewable energy analysis for an intentional community, Wild Mountain, who would like to decrease their dependence on fossil fuel sources for energy. The homestead’s goal is to further move toward targets of environmental sustainability and eco-justice. Our methods involved a partial energy audit recording the energy usage at the homestead, focusing on the electricity usage, and energy consumption used for heating. Three renewable energy sources were researched and evaluated to assess their viability for offsetting estimated fossil-fuel based energy usage. These three technologies are solar electricity production, methane digestion, and compost heap heating. Calculations and data synthesis were conducted to determine the best energy options for Wild Mountain. These calculations mainly centered around total energy usage, the corresponding greenhouse house emission equivalents, and inputs available at the homestead for the renewable technologies. Synthesis involved taking the calculations to construct energy production scenarios and other determinants of the data; from this recommendations are given on the viability of the renewable technologies being implemented at Wild Mountain. Significant assumptions for data, calculations, and other parts of the project are outlined in the appendices, in order to make the report’s main body more concise. Overall energy usage was found to be 145.41 mmBTUs/year of the parts of the energy usage studied. Attached to this number is the greenhouse emissions equivalents 24319.3 kg CO 2 equivalents. For organic inputs available at the homestead 35295 pounds per year is computed. Solar energy calculations focused on the number of panels necessary to produce electrical energy at certain levels of the homestead’s electrical usage. A 9-panel system that would offsetting a minimum portion of the electrical use that the co-operative wanted to focus on, and a 19-panel system that covers all the known electrical usage. The methane digester depending on design could produce substantial amount of energy. Compost Heap Heating was found to have a theoretical maximum energy production of 163.8 mmBTU per year using the organic inputs available from the homestead. To help conceptualize the results, scenarios involving the implementation of the renewable technologies were constructed to further analyze which renewable technologies would be more ideal in energy production and offsetting the current sources of energy. Five scenarios combined different partnerships of renewable energy and spatial heating in order to compare costs, energy production, and offsetings of current fossil fuel sources across technologies. Recommendations out of the scenario model put forth results for Wild Mountain to consider rather than ranking one scenario more ideal than the others. Other recommendations are made based on the research and results in general, from specific consideration for the technologies to energy conservation

Senior Recital: Ethan Machamer, Trombone; Lu Witzig, Piano; Joseph Buczko, Trombone; Connor Franke, Trombone; Peyton Gray, Trombone; Nick Sisson, Trombone; Charlie Machamer, Piano; Jack O\u27Mahony, Bass; Sean Duffy, Drums; April 6, 2024

Kemp Recital HallApril 6, 2024Saturday Evening4:00 p.m

The Treatment of People with Mental Illness in the Criminal Justice System: The Example of Oneida County, New York

This publication is two-fold: an executive summary and the report itself. The executive summary provides a general overview of the larger report, on the criminalization of the mentally ill. It begins by summarizing three case studies from the report that concern the intersection of mental health issues and the criminal justice system in Oneida County in New York State. It then provides a brief historical overview of mental health issues and the criminal justice system before going on to discuss the current best practices in addressing the criminalization of the mentally ill, including law-enforcement mechanisms, mental health courts, and reintegration programs. Next, the paper identifies the shortcomings of these practices and the lack of organizational and financial capacity that hobbles concerned stakeholders from effectively tackling the issue. The paper concludes by proposing a general program for immediate action on local and national scales

Wolbachia wStri blocks Zika virus growth at two independent stages of viral replication

Mosquito-transmitted viruses are spread globally and present a great risk to human health. Among the many approaches investigated to limit the diseases caused by these viruses are attempts to make mosquitos resistant to virus infection. Coinfection of mosquitos with the bacterium Wolbachia pipientis from supergroup A is a recent strategy employed to reduce the capacity for major vectors in the Aedes mosquito genus to transmit viruses, including dengue virus (DENV), Chikungunya virus (CHIKV), and Zika virus (ZIKV). Recently, a supergroup B Wolbachia wStri, isolated from Laodelphax striatellus, was shown to inhibit multiple lineages of ZIKV in Aedes albopictus cells. Here, we show that wStri blocks the growth of positive-sense RNA viruses DENV, CHIKV, ZIKV, and yellow fever virus by greater than 99.9%. wStri presence did not affect the growth of the negative-sense RNA viruses LaCrosse virus or vesicular stomatitis virus. Investigation of the stages of the ZIKV life cycle inhibited by wStri identified two distinct blocks in viral replication. We found a reduction of ZIKV entry into wStri-infected cells. This was partially rescued by the addition of a cholesterol-lipid supplement. Independent of entry, transfected viral genome was unable to replicate in Wolbachia-infected cells. RNA transfection and metabolic labeling studies suggested that this replication defect is at the level of RNA translation, where we saw a 66% reduction in mosquito protein synthesis in wStri-infected cells. This study’s findings increase the potential for application of wStri to block additional arboviruses and also identify specific blocks in viral infection caused by Wolbachia coinfection.R01 AI099210 - NIAID NIH HHSPublished versio

Systematic Review of the Relationships Between Objectively Measured Physical Activity and Health Indicators in School-Aged Children and Youth

Moderate-to-vigorous physical activity (MVPA) is essential for disease prevention and health promotion. Emerging evidence suggests other intensities of physical activity (PA), including light-intensity activity (LPA), may also be important, but there has been no rigorous evaluation of the evidence. The purpose of this systematic review was to examine the relationships between objectively measured PA (total and all intensities) and health indicators in school-aged children and youth. Online databases were searched for peer-reviewed studies that met the a priori inclusion criteria: population (apparently healthy, aged 5–17 years), intervention/exposure/comparator (volumes, durations, frequencies, intensities, and patterns of objectively measured PA), and outcome (body composition, cardiometabolic biomarkers, physical fitness, behavioural conduct/pro-social behaviour, cognition/academic achievement, quality of life/well-being, harms, bone health, motor skill development, psychological distress, self-esteem). Heterogeneity among studies precluded meta-analyses; narrative synthesis was conducted. A total of 162 studies were included (204 171 participants from 31 countries). Overall, total PA was favourably associated with physical, psychological/social, and cognitive health indicators. Relationships were more consistent and robust for higher (e.g., MVPA) versus lower (e.g., LPA) intensity PA. All patterns of activity (sporadic, bouts, continuous) provided benefit. LPA was favourably associated with cardiometabolic biomarkers; data were scarce for other outcomes. These findings continue to support the importance of at least 60 min/day of MVPA for disease prevention and health promotion in children and youth, but also highlight the potential benefits of LPA and total PA. All intensities of PA should be considered in future work aimed at better elucidating the health benefits of PA in children and youth

HIV treatment for prevention

"No virus, no transmission." Studies have repeatedly shown that viral load (the quantity of virus present in blood and sexual secretions) is the strongest predictor of HIV transmission during unprotected sex or transmission from infected mother to child

Can We Predict Burnout among Student Nurses? An Exploration of the ICWR-1 Model of Individual Psychological Resilience

The nature of nursing work is demanding and can be stressful. Previous studies have shown a high rate of burnout among employed nurses. Recently, efforts have been made to understand the role of resilience in determining the psychological adjustment of employed nurses. A theoretical model of resilience was proposed recently that includes several constructs identified in the literature related to resilience and to psychological functioning. As nursing students are the future of the nursing workforce it is important to advance our understanding of the determinants of resilience in this population. Student nurses who had completed their final practicum were invited to participate in an online survey measuring the key constructs of the ICWR-1 model. 422 students from across Australia and Canada completed the survey between July 2014 and July 2015. As well as several key demographics, trait negative affect, mindfulness, self-efficacy, coping, resilience, and burnout were measured. We used structural equation modeling and found support for the major pathways of the model; namely that resilience had a significant influence on the relationship between mindfulness, self-efficacy and coping, and psychological adjustment (burnout scores). Furthermore, as predicted, Neuroticism moderated the relationship between coping and burnout. Results are discussed in terms of potential approaches to supporting nursing students who may be at risk of burnout

Cross-Sample Validation Provides Enhanced Proteome Coverage in Rat Vocal Fold Mucosa

The vocal fold mucosa is a biomechanically unique tissue comprised of a densely cellular epithelium, superficial to an extracellular matrix (ECM)-rich lamina propria. Such ECM-rich tissues are challenging to analyze using proteomic assays, primarily due to extensive crosslinking and glycosylation of the majority of high Mr ECM proteins. In this study, we implemented an LC-MS/MS-based strategy to characterize the rat vocal fold mucosa proteome. Our sample preparation protocol successfully solubilized both proteins and certain high Mr glycoconjugates and resulted in the identification of hundreds of mucosal proteins. A straightforward approach to the treatment of protein identifications attributed to single peptide hits allowed the retention of potentially important low abundance identifications (validated by a cross-sample match and de novo interpretation of relevant spectra) while still eliminating potentially spurious identifications (global single peptide hits with no cross-sample match). The resulting vocal fold mucosa proteome was characterized by a wide range of cellular and extracellular proteins spanning 12 functional categories

Iron loading and disease surveillance.

Iron is an oxidant as well as a nutrient for invading microbial and neoplastic cells. Excessive iron in specific tissues and cells (iron loading) promotes development of infection, neoplasia, cardiomyopathy, arthropathy, and various endocrine and possibly neurodegenerative disorders. To contain and detoxify the metal, hosts have evolved an iron withholding defense system, but the system can be compromised by numerous factors. An array of behavioral, medical, and immunologic methods are in place or in development to strengthen iron withholding. Routine screening for iron loading could provide valuable information in epidemiologic, diagnostic, prophylactic, and therapeutic studies of emerging infectious diseases