1,895 research outputs found
Incidence of anthelmintic resistance in cattle farms in Northern Germany – first results
Anthelmintic resistance (AR) is an increasing problem worldwide especially for small ruminants and it is also rising in cattle. To maintain the efficacy of anthelmintics is an important objective. The current project aims at the investigation of the current efficacy of macrocyclic lactone anthelmintics for strongylid nematodes in first season grazing (FSG) calves in Northern Germany. On 8 participating farms in Northern Germany faecal egg count reduction tests (FECRT) with ivermectin (IVM) were performed. On 3 farms the efficacy of IVM was found to be ≤90% and on only 4 farms it was > 95% at 14 days post treatment (d.p.t.). Only 2 farms showed a reduction ≥ 95% at 21 d.p.t.. This survey reveals a rising problem of AR. The problem of drug resistance places the welfare of animals at risk. In organic farming, without a preventive treatment, livestock may harbour high worm counts. Therefore it is necessary to maintain powerful anthelmintic drugs to guarantee the welfare of animals that need salvage treatment. To investigate the AR problem in cattle more surveys with different anthelmintic drug classes are urgently needed
Remarks on E11 approach
We consider a few topics in approach to superstring/M-theory: even
subgroups ( orbifolds) of , n=11,10,9 and their connection to
Kac-Moody algebras; subgroup of and coincidence of one of
its weights with the weight of , known to contain brane charges;
possible form of supersymmetry relation in ; decomposition of
w.r.t. the and its square root at first few levels; particle orbit
of . Possible relevance of coadjoint orbits method is
noticed, based on a self-duality form of equations of motion in .Comment: Two references adde
A group model for stable multi-subject ICA on fMRI datasets
Spatial Independent Component Analysis (ICA) is an increasingly used
data-driven method to analyze functional Magnetic Resonance Imaging (fMRI)
data. To date, it has been used to extract sets of mutually correlated brain
regions without prior information on the time course of these regions. Some of
these sets of regions, interpreted as functional networks, have recently been
used to provide markers of brain diseases and open the road to paradigm-free
population comparisons. Such group studies raise the question of modeling
subject variability within ICA: how can the patterns representative of a group
be modeled and estimated via ICA for reliable inter-group comparisons? In this
paper, we propose a hierarchical model for patterns in multi-subject fMRI
datasets, akin to mixed-effect group models used in linear-model-based
analysis. We introduce an estimation procedure, CanICA (Canonical ICA), based
on i) probabilistic dimension reduction of the individual data, ii) canonical
correlation analysis to identify a data subspace common to the group iii)
ICA-based pattern extraction. In addition, we introduce a procedure based on
cross-validation to quantify the stability of ICA patterns at the level of the
group. We compare our method with state-of-the-art multi-subject fMRI ICA
methods and show that the features extracted using our procedure are more
reproducible at the group level on two datasets of 12 healthy controls: a
resting-state and a functional localizer study
Dynamik der Radonfolgeprodukt-Aktivität imSpeichel nach therapeutischer Radon-Exposition
Radon decay product activity was measured in saliva of 10 male patients 20-30 min after a 1-hour radon exposure in the gallery of the Gasteiner Heilstollen (radon activity 36.2 kBq/m(3), radon progeny activity 20.3 kBq/m(3)), in 1 patient showing relatively high activity (75th percentile) measurements were continued until 65 min after exposure. Patients were asked to collect about 2 mi of saliva in the mouth and produce it on a filter. After drying the filter at 300 degrees C, radon progeny activity was measured. Activity (median) at 20-30 min after leaving the treatment area was 4.5 Bq (25th percentile 1 Bq; 75th percentile 21 Bq). In the patient who underwent additional measurements the activity showed a further increase up to 29 Bq (35 min after radon exposure) before it continuously decreased to a very low activity (1-3 Bq) at 65 min after exposure. The results show that a significantly increased radon decay product activity is found in saliva after speleotherapeutic radon exposure. Maximum values were observed 35 min after radon exposure. Radon decay product activity almost disappeared after about 1 h
The attentional blink modulates activity in the early visual cortex
The attentional blink (AB) documents a particularly strong case of visual attentional competition, in which subjects' ability to identify a second target (T2) is significantly impaired when it is presented with a short SOA after a first target (T1). We used functional magnetic resonance imaging to investigate the impact of the AB on visual activity in individually defined retinotopic representations of the target stimuli. Our results show reduction of neural response in V3 and marginally in V2 and V1, paralleling the behavioral AB effect. Reduction of visual activity was accompanied by reduced neural response in the inferior parietal cortex. This indicates that attentional competition modulates activity in higher-order parietal regions and the early visual cortex, providing a plausible neural basis of the behavioral AB effect
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