7 research outputs found
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Abadia M
- Abassy J
- Abate E
- Abbott Tom EF
- Abdelaal Samir A
- Abdeldayem H
- Abdelkabir M
- Abdelsamed A
- Abdulwahed E
- Abiyere H
- Abou Chaar MK
- Abukhalaf SA
- Abukhalaf Sadi
- Adamina Michel
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adeyeye A
- Adisa Adewale
- Afzal MF
- Agarwal Arnav
- Aggarwal M
- Agnes A
- Agostini C
- Agrawal A
- Agrawal N
- Agresta F
- Aguiar Junior S
- Ahmed A
- Ahmed K
- Ahmed Nafees R
- Ahmed Z
- Ahn JH
- Aime A
- Akhtar N
- Akkulak Murat
- Akrivou D
- Al Abdallah M
- Al Riyami S
- Al Sayed M
- Al-Masri M
- Al-Najjar H
- Al-Slaibi I
- Alaa S
- Alakaloko Felix
- Alameer Ehab
- Alamri Alex
- Alawneh F
- Albertsmeier M
- Albertsmeier Markus
- Alderson Derek
- Aldokali N
- Alemanno G
- Alfieri S
- Algallai M
- Ali AA
- Alkadiki Ghadah Z
- Almaadany Faraj S
- Almeida AC
- Almeida-Reis R
- Almezghwi H
- Almond Max
- Alrahawy M
- Alser Osaid
- Alshaar Muhammad
- Alshareea E
- Alshareef K
- Alshryda Sattar
- Alsoufi A
- Altamirano Riquoir C
- Altomare DF
- Altomi I
- Alurralde C
- Alvarez MR
- Alvi A
- Alwarfly S
- AlZAEDE S
- Alzeerelhouseini IAH
- Amaral MJ
- Amira G
- Amorim E
- Amrani L
- Anania G
- Anastasi A
- Andrade Kam da Silva A
- Andrade R
- Annessi V
- Annicchiarico A
- Antonakis P
- Antonopoulou M
- Aprile A
- Aremu M
- Arias-Amezquita F
- Aribi N
- Aribi S
- Arkadopoulos N
- Armao T
- Armatura G
- Arminio A
- Arnaud Alexis P
- Arora A
- Arslan K
- Ashoush F
- Athanasakis E
- Attia D
- Augestad Knut Magne
- Aversano A
- Avlund T
- Awada Barakat J
- Ayasra F
- Ayasra Faris
- Ayasra Y
- Ayub B
- Ayubi A
- Ayyaz M
- Azevedo C
- Azevedo J
- Azevedo Jose
- Azevedo P
- Azman Mohd ZA
- Azzam AY
- Babalola O
- Badra R
- Bagraith K
- Baili E
- Balabel M
- Balconi A
- Baldari L
- Baldi C
- Baldini E
- Bali K
- Ballabio M
- Ballouhey Q
- Baloyiannis I
- Bandovas JP
- Bankhead-Kendall Brittany K
- Banky B
- Banuelos Romero E
- Baptista VH
- Barker D
- Barlow Emma
- Barod Ravi
- Barone R
- Baronio G
- Barrat B
- Barros Vieira A
- Bartalucci B
- Bartolini I
- Bashir Y
- Bass G
- Batistotti P
- Batstone Martin
- Baxevanidou K
- Beard David
- Becker R
- Bekele K
- Belia F
- Belkhadir ZH
- Bellacci A
- Belli A
- Bellolio F
- Bellora P
- Belluco C
- Belvedere A
- Bendjemar L
- Benkabbou A
- Benson Ruth A
- Bergamini C
- Bergeat D
- Bernante P
- Berselli M
- Bertelli G
- Bertolani E
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- Beyer K
- Beyrne C
- Bezerra Santos T
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- Bhat GA
- Bhat MA
- Biala M
- Bianchini M
- Bianco F
- Biel Juan Rey
- Bigam D
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- Boeker C
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- Bong C
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- Bonilla A
- Bonnet S
- Bordoni P
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- Bouchagier K
- Bouche PA
- Bouliaris K
- Boutros M
- Bowman S
- Boyce R
- Brachini G
- Bradulskis S
- Braham H
- Brar Amanpreet
- Bravo Ana Minaya
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- Bretherton Chris
- Bristow Rob
- Bromage Steve
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- Brunelli Alessandro
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- Burgan D
- Burke Joshua
- Butt U
- Bywater Edward
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- Calabro M
- Camacho C
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- Camarneiro R
- Caminsky N
- Campagnaro T
- Canas-Martinez A
- Canonico G
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- Capezzuoli L
- Capolupo GT
- Capunge I
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- Carissimi F
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- Carvello MM
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- Cassinotti E
- Catena F
- Cecire J
- Ceelen W
- Ceretti Pisani A
- Cervellera M
- Cetares C
- Chaar Mohammad
- Chakrabortee Sohini
- Chan E
- Charalabopoulos A
- Charre L
- Chaturvedi A
- Chaturvedi H
- Chatzikomnitsa P
- Chaudhry Daoud
- Chebaro A
- Chen S
- Chessa A
- Chiappini A
- Chiarugi M
- Chinda J
- Chiozza M
- Chisthi M
- Chiva Luis
- Choong E
- Chowdri N
- Christensen P
- Christensen Peter
- Christidis P
- Christou C
- Chrysos E
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- Cianflocca D
- Cicerchia PM
- Cirillo B
- Clarizia G
- Claro M
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- Cocozza E
- Coelho Nunes M
- Coffey JC
- Cohen Paul
- Colletti G
- Colombo F
- Colquhoun Alexandra
- Confalonieri M
- Connelly T
- Conti L
- Contis I
- Coonar Aman S
- Corbellini C
- Cordera F
- Corless K
- Corrigan M
- Cosentino Marino L
- Cosimelli M
- Costa M
- Costa Matos P
- Costa MJMA
- Costanzi A
- Costeira B
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- Cotte E
- Cox Daniel
- Cozza V
- Creavin B
- Cremonini C
- Crespo A
- Cuasquen Velasquez BG
- Cukier M
- Cukier Moises
- Cullivan O
- Cunha C
- Cunha MF
- Cunha Miguel F
- Cunha R
- Cunningham RM
- D'Aloisio G
- D'Ugo D
- D'Ugo S
- D'Urso A
- da Cruz Lima L
- da Silva Abreu A
- da Silva Lima C
- Dainius E
- Dajani K
- Daly A
- Danias N
- Davidson Giana H
- Dawson AC
- Dawson Brett E
- de Almeida Ramalho F
- de Barros Figueiredo
- De Lima RK
- De Lucia F
- De Nardi P
- De Palma G
- de Sa Correia T
- de Sampaio Regina L
- De Simone V
- De Sousa X
- De Toma G
- De Troia A
- De Vincenti R
- Deirino A
- Delinasios G
- Dell A
- Della Giustina E
- Dellaportas D
- Delrio P
- Demetriades Andreas K
- Demyttenaere S
- Denet C
- Depalma N
- Derksen T
- Desai Anant
- Desio M
- Desoouza A
- Deus AC
- Devarakonda S
- Devezas V
- Devine M
- Dhamija P
- Dharanipragada K
- Di Bella A
- Di Franco G
- Di Lauro K
- Di Martino C
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- Domingues J
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- dos Santos Martins G
- Doudakmanis C
- Dowdy Sean
- Doyle A
- Drake Thomas M
- Drane A
- Droghetti M
- Duchalais E
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- Earley H
- Eastmond A
- Ebbehoj AL
- Ebben L
- Economopoulou P
- Edwards John
- Edwards John G
- Efthimiou M
- Egoroff N
- El Ahmadi B
- El Amrani M
- El Arbi N
- El Bouazizi Y
- El Kassas M
- Elazzazy E
- Eldaly A
- Elghazaly MS
- Elhadi Muhammed
- Elliott JA
- Ellojli I
- Elmorsi R
- Emile Sameh
- Emmanuel K
- Enoch E
- Esene Ignatius
- Eskinazi DG
- Esposito G
- Esquide Ruiz M
- Essam E
- Evans Jonathan P
- Evans Richard PT
- Eveno C
- Ewedah M
- Ezanno AC
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- Facundo H
- Fagotti Anna
- Fahey BA
- Fahmawee T
- Farik Shebani
- Farnesi F
- Farooka MW
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- Faustino A
- Fayed Y
- Federico P
- Federico Pipitone NS
- Feo C
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- Fernandes U
- Fernandes V
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- Ferrario L
- Ferraz I
- Ferreira C
- Ferreira Peralta M
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- Ferro Rey M
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- Fiore M
- Fiore Marco
- Fiori E
- Fiorini A
- Fitzgerald J Edward
- Flamey N
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- Franken J
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- Fujiwar Keiichi
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- Griffiths Ewen A
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- Grotenhuis BA
- Gruber R
- Gruendl Magdalena
- Guadagni S
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- Guerci C
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- Guevara O
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- Gutelkin Murat
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- Hamdan KH
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- Impellizzeri H
- Inama M
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- Inzunza M
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- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/06/2022
- Field of study
AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4âweeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4âweeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, PÂ =Â 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, Pâ<â0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, PÂ =Â 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, PÂ =Â 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
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- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Aawsaj Y
- Abadia M
- AbadâGurumeta A
- AbadâMotos A
- Abassy J
- Abate E
- Abbasov A
- Abbott D
- Abbott Tom EF
- Abdalla M
- Abdeldayem H
- Abdelkabir M
- Abdelkader Salama I
- Abdelkarim M
- Abdelsamed A
- Abdulfattah F
- Abdulwahed E
- AbdurâRahman LO
- Abel MK
- Abelevich A
- Abiyere H
- Aboelkassem Ibrahim A
- Aboharp Hasan Z
- Abou Chaar MK
- Abreu da Silva A
- Abubakar A
- Abukhalaf SA
- Abukhalaf Sadi
- Acebes GarcĂa F
- Achalandabaso Boira M
- Acher A
- Acosta MĂ©rida MA
- Acrich E
- Adam Essa Adam ME
- Adamina M
- Adamina Michel
- Adamina Michel
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Aderombi A
- Adeyeye A
- Adeyeye A
- Adi H
- Adiamah A
- Adisa Adewale
- Afzal MF
- Agapov M
- Agarwal Arnav
- Aggarwal M
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agrawal A
- Agrawal N
- Agresta F
- Aguado LĂłpez H
- Aguiar JĂșnior S
- Aguilar Gonzalez M
- Ahmed A
- Ahmed A
- Ahmed K
- Ahmed ME
- Ahmed Z
- Ahmeidat A
- Ahn JH
- Aiken T
- Aimé A
- Akalin M
- Akaydin E
- Akbas A
- Akhtar MA
- Akhtar N
- Akhter Rahman MM
- Akin E
- Akkulak Murat
- Akrivou D
- Al Abdallah M
- Al ahmad F
- Al Asadi T
- Al Awwad S
- Al Ayed A
- Al Habes H
- Al Riyami S
- AL Sayed M
- Alaa S
- AlAamer O
- Aladeojebi A
- Alagoa Joao A
- Alakaloko Felix
- Alam F
- Alameer Ehab
- Alamri Alex
- Alanazi F
- Alawneh F
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- Kamel F
- Kamera BS
- Kamoka E
- Kamphues C
- Kanemitsu Y
- Kannummal Veetil S
- Kanthasamy S
- Kapoor S
- Kappenberger A
- Kara H
- Kara Y
- Karahasanoglu T
- Karaitianos IG
- Karamarkovic A
- Karandikar S
- Karim A
- Karimuddin A
- KarloviÄ D
- Kashif M
- Kasivisvanathan Veeru
- Kassir R
- Katory M
- Kattakayam A
- Katusic Z
- Kaul S
- Kauppila JH
- Kauppila JH
- Kaushal M
- Kavanagh D
- Kaya T
- Kayyal MY
- Kazachenko E
- Keatley James M
- Kebabçı E
- KecmanoviÄ D
- Keeler BD
- Keller Debby
- Keller Debby
- Kembuan G
- Kenic M
- Kennelly R
- Kent A
- Kerawala AA
- Khajuria A
- Khan A
- Khan AH
- Khan F
- Khan J
- Khan K
- Khan S
- Khan Tabassum
- Khatri Chetan
- Khaw Rachel A
- Khokhar MI
- Kiconco H
- Kilani AI
- Kilinc Tuncer G
- Killeen S
- Kim NJ
- Kirmizi Y
- Kjaer DW
- Klaristenfeld D
- Klatte Tobias
- Kleeff J
- Kler A
- Klimopoulos S
- Kloppers C
- KmeziÄ S
- Knezevic D
- Knight Andrew
- Knights E
- Knowles C
- Knowles J
- Kocatas A
- Koh A
- Kokkinos G
- Kokobelyan AK
- Kokoropoulos P
- Koleva Radica M
- Kolias Angelos
- Kolias Angelos
- Kolla C
- Kollengode VV
- Kolli VS
- Konney Thomas
- Konstadoulakis M
- Konstantinou C
- Konsten J
- Kontovounisios C
- Kornblith LZ
- Kottayasamy Seenivasagam R
- Koukoulis G
- Kourdouli A
- Kovacevic B
- Kowalewski P
- Krarup P
- Krdzic I
- Kredan A
- Kretzmer L
- Krishnan E
- Kristensen HĂ
- Krivokapic Z
- Kroon HM
- Kruijff Schelto
- KrĆĄul D
- Kubiliute E
- Kubyshkin V
- Kucuk GO
- Kudchadkar S
- Kuiper S
- Kulkarni N
- Kulkarni R
- Kulle CB
- Kumar A
- Kumar L
- Kumar S
- Kumar V
- KutkeviÄius J
- Kuttanchettiyar KG
- KwanâFeinberg R
- Kwiatkowski A
- Kyriacou H
- KÀlviÀinen H
- Königsrainer A
- KĂŒĂ§ĂŒk IF
- La Regina D
- La Torre F
- Labib PL
- Lacy AM
- Ladd MR
- Laface L
- Laforest A
- Laharwal A
- Lakkis Z
- Lala AK
- Lalou L
- Lamb Benjamin
- Landaluceâolavarria A
- Lapolla P
- Laporte G
- Larentzakis A
- Larkin J
- Laskar N
- Lasses MartĂnez B
- LatinÄiÄ S
- Lauretta A
- Lauscher J
- Lavy R
- Law J
- Lawani Ismail
- Lawday S
- Lawday Samuel
- Lawday Samuel
- Layton Georgia R
- Le Roy B
- Lecolle K
- Lederhuber Hans
- Lederhuber Hans
- Ledesma FS
- Lee M
- Lee N
- Leede E
- Lenzi E
- Leon R
- Leung Elaine YL
- Leventoglu Sezai
- Leventoglu Sezai
- LewisâLloyd C
- Li Elizabeth
- Li Elizabeth
- Li M
- Li Z
- Liakakos T
- Liao CCL
- Lieske B
- Lim M
- Lim RZM
- Lima Buarque I
- Lima da Cruz L
- Lima da Silva C
- Lima MJ
- Linari C
- Lippa Laura
- Lira dos Santos Leite A
- Litta F
- Litvin A
- Litvin Andrey
- Litvina Y
- Liu J
- Liu T
- Lizzi V
- Locatelli A
- Loch FN
- Loehrer A
- Loehrer Andrew
- Loncar Z
- Long C
- Longhi M
- Longhini A
- Longstaff L
- Lopes L
- Lopez Abad A
- LoraâCumplido P
- Lorena Maria Aguilera
- Lorenzon L
- Losada M
- Lott N
- Loubani M
- Loutzidou L
- Lowery A
- Lozano Lominchar P
- Lucchini SM
- Luglio G
- Lule H
- Lun EWY
- Lunevicius R
- Lunghi EG
- Lynch N
- Lyons A
- LĂĄzaro A
- López Antoñanzas L
- Löffler Markus W
- Löffler MW
- Löfgren N
- M. elghazaly S
- Maa Albared S
- Maccabe TA
- MacDonald L
- Machado D
- Machado N
- Macina S
- Madani Kia T
- Madani R
- Madonini M
- Maffioli A
- Magee C
- Maghrebi H
- Magowan D
- Mahajan A
- Mahendran V
- Mahmood M
- Mahmoud Ali F
- Mahvi D
- Maida P
- Maiga A
- Maimbo Mayaba
- Majbar AM
- Majkowska A
- Major P
- Major Piotr
- Majrashi S
- Majumdar KS
- Mak TWC
- Malapati H
- Malcolm FL
- Malgras B
- Malibary N
- Mall JW
- Maltinti G
- Manatakis DK
- Manfredelli S
- Manku B
- Mann Harvinder S
- Manrique E
- Manso I
- Manson J
- Mantoglu B
- Manu N
- Maqueda GonzĂĄlez R
- Marafante C
- Marano A
- Marchbank Adrian
- MarcosâSantos P
- Marcus Hani J
- Mardare M
- Margalit A
- Mari G
- Marialva J
- Mariani NM
- MarieâMacron L
- Marinello P
- Marino Cosentino L
- Marino M
- Marino MV
- Markaryan D
- Markovic I
- Markovic V
- Marques R
- Marques T
- Marqueta De Salas M
- Marra AA
- Marra E
- Marreiro A
- Marson Ella J
- Marte G
- Martel A
- Martin E
- Martin E
- Martin Janet
- Martin ST
- Martinek L
- Martinez German A
- Martins dos Santos G
- Martins JordĂŁo D
- Martins A
- Martins D
- Martins R
- MartinâPerez B
- MartinâPerez E
- MartĂn Anoro LF
- MartĂn L
- MartĂnez Chicote C
- MartĂnezâHurtado E
- MartĂnezâPinedo C
- MartĂnezâPĂ©rez P
- MartĂnâArĂ©valo J
- Marx W
- Marzi F
- Marçal A
- MarĂn H
- Masciandaro A
- Mashat A
- Mashbari Hassan N
- Massey LH
- Massie E
- Massobrio A
- Mastoridis S
- Math S
- Mathew S
- MatiÄ S
- Matos Costa P
- Matute M
- Maté Mate P
- MatĂasâGarcĂa B
- Maw A
- Mazingi Dennis
- Mazzotta E
- Mazzotti F
- McAleer J
- McAree B
- McCanny A
- Mccluney S
- Mccormick P
- McDermott FD
- McElhinney K
- McEwen R
- McGivern K
- McGrath John S
- McIlmunn C
- McIntosh S
- McIntyre J
- McKay Siobhan
- Mckay Siobhan C
- McKevitt K
- McLean Kenneth A
- McNaught C
- McNeill Alan
- McNicol F
- MdRazali. I null
- Mehigan BJ
- Mehraj A
- Meimaâvan Praag EM
- Mekhael M
- MelchorâRuan J
- Melenhorst J
- Melhem S
- Memon AS
- Memos N
- Mendes F
- Mendes JR
- MendozaâMoreno F
- Meneghini S
- Mercado MĂ
- Merdrignac A
- Merh R
- Meriç S
- Messner F
- Metallidis Symeon
- Metwalli M
- Metzger J
- Michalopoulos N
- Michalski C
- Michel M
- Micic D
- Migliore M
- Mignot G
- Miguel T
- Mihanovic J
- Mihmanli M
- Miladinov M
- MilanoviÄ M
- Milic LJ
- Mills Emily C
- Mills SJ
- Milne K
- Minaya Bravo AM
- MinayaâBravo Ana
- MinayaâBravo Ana
- MinayaâBravo Ana
- Mingoli A
- Minicozzi A
- Minto G
- Mir I
- Mirabella A
- Miranda P
- Mirica RM
- Mirnezami R
- Mishra N
- Mishra S
- Mishra T
- Misra S
- Mitchell D
- Mitchell S
- Mithany R
- Mitra JK
- Mitrofan C
- Mittal R
- Mittal Rohin
- Miu V
- Mochet S
- Modolo Maria Marta
- Modolo Maria Marta
- Moftah M
- Moggia E
- Mohamed Sidek AS
- Mohammad Z
- Mohammed MM
- MohammedJibreel M
- Mohan H
- Mohan Helen M
- Mohan Helen M
- Mohd Azman ZA
- Mohd Yunus MF
- Mohsine R
- Mongelli F
- Montauban P
- Montelatici M
- Monteleone M
- Montella MT
- Montori G
- Montuori M
- Moore Rachel
- Moorthy M
- Morais H
- Moras L
- MoraâGuzmĂĄn I
- Morelli L
- Moretto G
- Morgan R
- Moritani K
- MoroâValdezate D
- Morris A
- Morsi A
- Mosley F
- Moss J
- Moszkowicz David
- Moug S
- Moug Susan
- Moug Susan
- Moura F
- Mourad M
- Mshelbwala P
- Msherghi A
- Mudawi I
- Muduly D
- Muguerza JM
- Muiesan P
- Mukherjee S
- Muller B
- Mulligan CS
- Mungo S
- Muratore A
- Murawa D
- Murgese A
- Murphy C
- Musetti S
- Mustafa A
- Mutter D
- Muzamil J
- Muñoz Camarena JM
- MuñozâAtienza V
- MuñozâBellvis L
- Naar L
- Nacif L
- Nafees Ahmed R
- Nageh MA
- Nahm C
- Najarian M
- Nally D
- Namazov Ä°
- Nankivell Paul
- Narahari Krishna
- Nassa H
- Nassif M
- Natale J
- Naumann D
- Navaratne L
- Nazir S
- Neary P
- Neary PM
- Neely D
- Negoi I
- Negoi Ionut
- Negoita VM
- Nel D
- Nelli T
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Neri J
- Nespoli LC
- Nessim C
- Neville Iuri
- Newman S
- Newman T
- Newton C
- Newton K
- Ng HJ
- Ng Joe
- Ng S
- Ng V
- Ng V
- Ngo CW
- NgâKamstra Joshua S
- NicolĂĄsâLĂłpez T
- Nikaj H
- Nikolaou S
- Nikolic S
- Niquen Milagros
- Nisar P
- Nitschke C
- Nogueira O
- Nogueiro J
- Nogués A
- Noiret B
- Nolan GJ
- Norcini C
- Nordberg M
- Notte F
- Nouh T
- Novello S
- Novikova A
- Nowak K
- Ntirenganya Faustin
- Nugent E
- Nunes Coelho M
- Nunes R
- NunezâGarcia B
- NunooâMensah JW
- Nuñez Del Barrio H
- Nwabuoku SE
- NĂșñez J
- Obeidat K
- Ocaña J
- OchagavĂa S
- Oguttu B
- Okafor B
- Okunlola A
- Olaogun J
- Olasehinde O
- Oldfield F
- Oliva Mompean F
- Oliveira A
- Olivier J
- Olivieri M
- Olivos Maricarmen
- Olori S
- Olson KA
- Olute A
- Omar W
- Omeroglu S
- Ong SL
- Onos L
- Oosterlinck W
- Oosterling S
- Opocher E
- Ortega VĂĄzquez I
- Ortiz de SolĂłrzano Aurusa FJ
- Ortiz LĂłpez D
- Osagie O
- Oseira A
- Osman N
- Osorio Ramos A
- Otero A
- Otoniel LR
- Oussama Kacimi
- Outani Oumaima
- Ovejero Merino E
- Owen H
- Owens P
- Oyende O
- Ozben V
- Ozcelık MF
- Ozgediz D
- Ozmen BB
- OâBrien H
- OâBrien S
- OâDonnell S
- OâMalley S
- OâRiordan J
- OâShea M
- P Delrio
- Pacheco SĂĄnchez D
- PadillaâValverde D
- Padmore G
- Pagano G
- Pajan H
- Palagi S
- Palma P
- Palmeri M
- Panahi P
- Pandey D
- Paniagua GarcĂa Señorans M
- Papaconstantinou I
- Papadopoulos V
- Papagni V
- Papatheodorou P
- Paquette N
- Parasyris S
- Pareek P
- Pareja Rene
- Parello A
- Parente A
- Parini S
- Parise P
- Park J
- Parkin E
- Parkins K
- Parlanti D
- Parmar C
- Parra Baños PA
- Parray FQ
- Parreira R
- ParreñoâSacdalan Marie Dione
- ParreñoâSacdalan Marie Dione
- Parseliunas A
- Parwaiz I
- Pasini F
- Paspaliari D
- Pata Francesco
- Pata Francesco
- Pata Francesco
- Patel Akshay
- Patel K
- Patel M
- Patel P
- Patil S
- Patrone R
- PatrĂcio B
- Pattyn P
- Pattyn P
- Pavlov M
- Pedrazzani C
- Pedro J
- Pedro V
- Peirce C
- Pejnovic L
- Pejovic I
- Pellegrino L
- Pellino G
- Pellino Gianluca
- Peluso C
- Penumadu P
- Pera R
- Peralta Ferreira M
- Pereca J
- Pereira Rodrigues A
- Pereira A
- Pereira C
- Pereira I
- Pereira R
- Perez Gonzalez M
- Perez D
- Pergolini I
- Perivoliotis K
- Peros G
- Perotto LO
- Perra T
- Perrone G
- Persad A
- Persiani R
- Pertile D
- Peteja M
- Petrillo A
- Peyroteo M
- Pezzuto AP
- Peña Ros E
- Peña Soria MJ
- Pham H
- Phan D
- Phang PT
- Phillips E
- Picardo AL
- Picciariello A
- Picciochi Maria
- Pickett L
- PicĂłn RodrĂguez R
- Pieniowski E
- Piessen G
- Pina S
- Pinilla Morales RE
- Pinkney Thomas D
- Pinotti E
- Pinto J
- Pipara A
- Piper Rory J
- Pipitone Federico NS
- Pirozzolo G
- Pirzada A
- Pisani Ceretti A
- Pisanu A
- Pius Ogolekwu I
- PlaâMarti V
- Pockney P
- Pockney Peter
- Pockney Peter
- Pockney Peter
- Podda M
- Poeze M
- Poggioli G
- Police A
- Polydorou A
- PolâFachin L
- Ponchietti L
- Popoola AA
- Porcu A
- Portinari M
- PosadasâTrujillo OE
- PosmaâBouman L
- Potter R
- Pourcher G
- Powell S
- Pozotou I
- Praetorius C
- Pramesh CS
- Prando D
- Presl J
- Price C
- Price Stephen J
- Prieto Calvo M
- Prieto Nieto MI
- Pronk AJM
- Prosperi P
- Provozina A
- Pruvot FR
- Pujari R
- Pujol Cano N
- PĂ©rez SĂĄnchez MA
- PĂ©rezâSaborido B
- Qadan M
- Qasem A
- Qatora MS
- Quante M
- Quintana Martinic M
- QuirogaâValcĂĄrcel A
- Qureshi Ahmad
- Qureshi AU
- RabyâSmith W
- Radenkovic Dejan
- Raggio E
- Rai L
- Rajan S
- Rajaretnam N
- Rakvin I
- Ramachandran A
- Ramalho de Almeida F
- Ramamoorthy R
- Ramasamy S
- Ramcharan S
- Ramesh P
- Ramirez Faraco M
- Ramirez Romero P
- Ramos Bonilla A
- Ramos D
- RamosâDe la Medina Antonio
- RamosâMartĂn P
- Ramwell A
- Rao S
- Rapaport S
- Rashid A
- Rashid MM
- Rasoaherinomenjanahary F
- Rattizzato S
- Ratto C
- Raval M
- Ravindrakumar S
- Ravindran S
- Rayamajhi S
- Raymond T
- Razafindrahita JB
- Recordare A
- Reddy P
- Redfern J
- Refky B
- Rega D
- Rega D
- Regina de Sampaio L
- Reilly J
- Reim D
- Reinhard T
- Revez T
- Rey Ferro M
- Rey Valcarcel C
- Reynolds IS
- Ribeiro A
- Ribeiro CG
- Ribeiro R
- Ribolla M
- Rice D
- Richards S
- Richards T
- Richards Toby
- Riddell A
- Ridgway PF
- Righini E
- Riley C
- Rimonda R
- Ringressi MN
- RipollĂ©sâMelchor J
- Riquoir Altamirano C
- Risaliti M
- Riva C
- Rivas R
- Rivera Carlos Jose Perez
- RiveraâAlonso D
- Rizk M
- Rizzi A
- Roberts Keith
- Roberts Keith
- Robertson Faith
- Robinson A
- Roca Calvo MJ
- Rodrigo VSD
- Rodrigues K
- Rodriguez Artigas JM
- Rodriguez JL
- RodrĂguez GĂłmez L
- Rodwell H
- Rogers LJ
- Rogers M
- Rojo LĂłpez JA
- RoldĂłn Golet M
- Romano M
- Romero Bañuelos E
- Romero de Diego A
- Ronellenfitsch U
- Rooney SM
- Rosa F
- Rose J
- Roslani AC
- Roslani April C
- Rosseau Gail
- Rossi S
- Roszkowski R
- Rottoli M
- Roux A
- Roxo V
- Roy Mahapatra S
- Royle T
- RubioâPerez I
- Ruivo A
- Ruiz Esquide M
- Ruiz Manzanera JJ
- Ruiz Soriano M
- RuizâEscobar A
- RuizâMarĂn M
- Russ J
- Russo IS
- RutegÄrd M
- RutegÄrd Martin
- RutegÄrd Martin
- Rutherford D
- Ruzgar NM
- Ruzzenente A
- Ryan M
- Ryan ĂJ
- Ryska O
- RĂo Lafuente FD
- S RRR
- Saad MM
- Saafan T
- Saavedra J
- Sabry A
- Saeed S
- Saez Carlin P
- Sagar J
- Sagnotta A
- Sahid Nik Amin
- Sahin I
- Sahnan K
- Saklani A
- Sakr A
- Saksena AR
- Salazar A
- Saleem A
- Saleem A
- Saleh M
- Salem H
- Salem H
- Salem M
- Salerno G
- Sales Mallafré R
- SalgadoâNesme N
- Salim A
- SalimoÄlu S
- Salindera S
- Sallam I
- Samadov E
- Samih A
- Samir Abdelaal A
- Samison LH
- Samkari A
- Sammarco G
- Sammour T
- Sampaio da NĂłvoa Gomes Miguel II
- Sampaio Soares A
- Sampietro GM
- San Miguel C
- Sanchez Cabezudo Noguera F
- Sanchez Gonzalez J
- Sanchez Jimenez R
- SanchezâCasado AB
- SanchezâPelaez D
- Sanchon L
- SanchoâMuriel J
- Sanli AN
- Santanach C
- Santarrufina Martinez S
- SanteroâRamirez MS
- Santos Bezerra T
- Santos IrĂšne
- Santos PMDD
- Santos R
- SantosâSousa H
- Sanz Larrainzar A
- Sanz Ortega G
- SanzâLĂłpez R
- Sapienza P
- Sapre D
- Saraiva P
- Sarantitis I
- Sarigul M
- Sarin A
- Sarjanoja E
- Sarma DR
- Sarpel U
- Sarre C
- Sartarelli L
- Sarveswaran J
- Sasapu K
- Sasia D
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- Satoi Sohei
- SaudĂ S
- Sauvain M
- Sauvat F
- Saverio Salomone Di
- Saverio Salomone Di
- SavkoviÄ N
- Sayyed R
- Sayyed Raza
- Scabini S
- Scalabre A
- Scanu AM
- Schache Andrew
- Schache Andrew G
- Schaller Karl
- Scheiwiller A
- Schiavo M
- Schiergens T
- Schineis C
- Schizas D
- Schlesinger N
- Schnitzbauer Andreas A
- Schwartz PB
- Scott L
- Scotton G
- Scrima O
- Sebai A
- Seebah K
- Seeliger B
- Seenivasagam Rajkumar Kottayasamy
- Seguinâgivelet A
- SeguraâSampedro JJ
- SeguraâSampedro Juan JosĂ©
- Sehgal T
- Sehouli Jalid
- Seleim A
- Selmani J
- Semina E
- Sena G
- Senossi O
- Serevina OL
- Serralta de Colsa D
- Serrano GonzĂĄlez J
- SerranoâNavidad M
- Sert Ä°
- Servadei Franco
- SeyiâOlajide Justina O.
- Seymour Z
- Sganga G
- SgrĂČ A
- Shah J
- Shah S
- Shah ZA
- Shaikh I
- Shaikh S
- Shakoor Z
- Shanthakunalan K
- Sharabiany S
- Sharma Neil
- Sharma P
- Shaw Catherine A
- Shaw Richard
- Shaw Richard
- Sheel A
- Shehata S
- Shenit K
- Sheridan K
- Sherief M
- Sherif A
- Sherif Ahmed Elshawadfy
- Sherif G
- Shokuhi P
- Sholadoye TT
- Shortland T
- Shream S
- Shrestha A
- Shu Sebastian
- Shylasree TS
- Sian T
- SiawâAcheampong Kwabena
- Sibilla MG
- Siddiqui MT
- Sidiropoulos T
- Silva A
- Silva M
- Silva N
- Silva R
- Silveira Nunes I
- Silvestre D
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- Singh AA
- Singh Jagdeep K
- Singh MP
- Singh R
- Singh S
- Singh S
- Sion M
- Skrovina M
- Smart Neil
- Smart Neil J
- Smith C
- Smith H
- Smith J
- Smith L
- Soh JY
- Sohrabi C
- Sokolov M
- Solari F
- Soldevila Verdeguer C
- Soliman H
- Soltan H
- Soreide Kjetil
- Soriano AI
- Soriero D
- Sorrentino L
- Sorribas Grifell M
- Sosa Duran EE
- SosaâRodrĂguez MV
- Soto Montesinos C
- Souadka A
- SoulĂ© MartĂnez CE
- Sousa Fernandes M
- Sousa R
- Sousa S
- Spagni G
- Spampinato MG
- Spanu A
- Spartalis E
- Spencer N
- Spiezio G
- Spinelli A
- Spinelli Antonino
- Spolini A
- Sreedharan L
- Srikumar B
- Sriram RK
- Srishankar S
- SroczyĆski P
- St John S
- Stafford J
- Stavrinidou O
- Stebbing J
- Steele C
- Steidle C
- Steinke J
- Stevens K
- Stevenson J
- Stevic D
- Stewart Grant D
- Stewart Grant D
- Stewart KE
- Stockdale T
- Stoica B
- Strate T
- Stylianides N
- Stylianidis G
- Subhi MT
- Subocius A
- Subramaniam S
- Sud A
- Sund Malin
- Sundar Sudha
- Sundar Sudha
- Sundaram Venkatesan G
- Sundhu M
- SusztĂĄk N
- Sutherland A
- Swinson B
- Syed WAS
- Syllaios A
- Szatmary P
- Szubota I
- SĂĄnchez del Pueblo C
- SĂĄnchez Fuentes N
- SĂĄnchez Tocino JM
- SĂĄnchezâGarcĂa S
- SĂĄnchezâGuillĂ©n L
- Tabiri Stephen
- Tactuk N
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- ĂÄĂŒcĂŒ H
- ĂberrĂŒck L
- Äoza I
- Ćawnicka A
- ĆœateckĂœ J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4âweeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4âweeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, PÂ =Â 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, PâConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Global Incidence and Risk Factors Associated With Postoperative Urinary Retention Following Elective Inguinal Hernia Repair
- Author
- Ali
- A. Rady Ahmed Hassan
- Aamir Faiqa B.
- Ababneh Hazim Sameer Mohammad
- Abaidalla Ahmed Faraj
- Abd Al-Fattah Mohammed
- Abd El-razik Sally Ahmed
- Abdelfattah Mohamed S.
- Abdelgalil Mahmoud Shaban
- Abdelhaleem Ibrahim A.
- Abdelmageed Abdelfatah A.
- Abdelwahid Elharith H.
- Abdulhamid Salaheddin M.
- Abdullah Areeba
- Abdullah Mohammad A.
- Abdullah Weaam M.
- Abdulmonem Aya Abdulilah
- Abdulwahed Eman A.
- Abelevich Alexander
- Abo Ghanima Shymaa M.
- Abotaleb Khadega
- Abozid Anwaar
- Abu Jayyab Mustafa A.
- Abu Reyash Tamara K.
- Abu-Arish Hamdoon
- Abu-Ismail Luai
- Abubakr Muhammad
- Abufaraj Mohammad
- Abuleil Amro
- Abuzeid Issa A.
- Adesunkanmi Abdul Hafiz O.
- Adeyeye Ademola Adetoyese
- Adinolfi Elvira
- Adwin Zainal Z.
- Afeikhena Ehis
- Agalianos Christos
- Ahmad Abrar
- Ahmad Hasan Y.
- Ahmad Shahzaib
- Ahmad Sharifa
- Ahmed Fathil Ida Nadiah
- Ahmed Samar G.
- Ahmed Shaheer
- Ahonkhai Irele Ifijeh
- Aimon Sibgha
- Aiolfi Alberto
- Ajekwu Samuel Chibuzo
- Aketch Martin Safari
- Akhtar Aamena
- Akhtar Hamza
- Akram Muhammad U.
- Aktas Ahmed
- Al Bastaki Aysha
- AL Hamoud Mohammad A.
- Al Sagheir Eman
- Al Shareeda Mohamad
- Al-Aydi Tala
- Al-Dhaheri Manal Jamal
- Al-Eryani Fatima
- Al-Eryani Salwa
- Al-Hajj Al-Fakih Wadhah Ahmed
- Al-Juaifari Maytham A.
- Al-Kubaisy Manolia
- Al-Nagdy Mohamed
- Al-Naggar Hamza
- Al-Saba'a Yousef K.
- Al-Shami Khayry
- Al-Shehari Mohammed
- AL-Wajeeh Ghadeer
- Alaa Sherif
- Alabad Madian
- Alabd Husayn M.
- Alahmad Ziad
- Alam Mansoor
- Alameen Hind
- Alaniz Alday Maria Jimena
- Alannaz Omar
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- Alberich Prats Marta
- Aldawoody Hogir I. R.
- Aldressi Wafa
- Alemad Shada
- Alfa Yakubu
- Alghareeb Rafah
- Alhaj Ahmad
- Alharazin Mohammed
- Alhasan Hasan
- Ali Ali
- Ali Ebrahim M.
- Ali Farjad
- Ali Wasaq
- Aliskander Fater
- Aljaber Ahmad
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- Allen-Brough Chelsea
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- Alozai Muhammad Ilyas
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- Alshareea Entisar
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- Alvarez-Lozada Luis Adrian
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- Aprea Giovanni
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- Attiya Omar
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- Charalabopoulos Alexandros
- Chatzimavroudis Grigorios
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- Chawla Tabish
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- Guevara MartiÌnez Jenny
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- Hussain Akbar
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- Iruthayanathar Andru Nitharasan
- Isik Arda
- Ismail Ruba S.
- Jabbar Naveed
- Jacob Prem Thomas
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- Koukoulis Georgios
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- Robb William B.
- Rodrigo Vitharanage Srimantha Dewsiri
- Rodriguez-Leon Gerardo
- RodriÌguez Cano MariÌa A.
- RodriÌguez GoÌmez Lorena
- Romanzi Andrea
- Rossi Stefano
- Rostum Zuhair
- Roy Dorina
- RuiÌz FriÌas Piedad
- Ryabkov Maxim
- Ryan Eanna
- Ryan Jessica M.
- Ryan Odhran K.
- Saad Aalaa
- Saad Ahmad
- Saad Reem J.
- Sadek Kareem
- Saeed Abdullah B.
- Saeed Reham J. M.
- Sainz-Lete Aitor
- Sakr Ahmad
- Sakr Yara
- Salih Mugahid A.
- Salih Saniye
- Saracoglu Kemal Tolga
- Sarwar Muhammad Zeeshan
- Sasia Diego
- Sawas Fatima
- Sayed Hafez Somaya Z. E
- SaÌnchez-Rubio MariÌa
- Scabini Stefano
- Schimera Antonio
- Schizas Dimitrios
- Scolaro Roberta
- Scorsi Alessandro
- Selvaggi Francesco
- Selvaggi Lucio
- Senhuri Alrayah E.
- Serrano-Navidad Monica
- Shaaban Abdelrahman
- Shafi Mahnoor
- Shah Syed Faraz Ali
- Shahab Tooba
- Shahbaz Usama
- Shaheen Ahmed
- Shalaby Mostafa
- Shami Sarah M.
- Shams Marvi
- Shanahan Ben
- Sharifa Mohammad
- Shehata Eslam S. A. M.
- Shetiwy Mohamed
- Shream Sarah
- Shuayb Ahlam M.
- Shulman Natassia
- Shumrakh Saeed K.
- Siggins Lauren
- Silva ClaÌudio
- Skroubis Georgios
- Soeda Seminario Isami
- Solaini Leonardo
- Soldevila-Verdeguer Carla
- Soriero Domenico
- Soto-SchuÌtte Sonia
- Sountoulides Petros
- Spoletini Domenico
- Srinivasan Madhu
- Stafford Anthony T.
- Sueiras Gil Albert
- Swindon Daisy
- Syllaios Athanasios
- Şahin Enes
- Şimşek Turgay
- Taha Sandy A.
- Tahir Izza
- Taktuk Salah S.
- Talpai TamaÌs
- Tammo Shergal
- Tanas Yousef
- Tarky Alhashash Ahmad
- Tasis Nikolaos
- Tatar Ozan Can
- Teker Kenan
- Telha Ghassan K.
- Telha Khaled A.
- Teng Roy
- Teoh Jeremy Y. C.
- Thompson-Fawcett Mark W.
- Tolani Musliu Adetola
- Toomey Desmond
- Torchiaro Marco
- Toubasi Ahmad A.
- Toum Fthelrahman M.
- Ukrani Ronika Devi
- ul Haq Syed Atif
- Umer Farooq
- Uprak Tevfik Kıvılcım
- Ur Rehman Sheeraz
- Vailas Michail
- Valderrabano Gonzalez Santiago
- Vallet Fernandez Josep
- Vannelli Alberto
- Varghese Chris
- VaÌzquez-Melero Alba
- Vignati Barbara
- Vigutto Gabriele
- Wang Huaxi
- Waqar Usama
- Weeratunga George
- Winter Des C.
- Winter Des C.
- Wong Benjamin Ngie Xiong
- Xenaki Sofia
- Xu William
- Y. Aljabarein Osama
- Yaghoub Ali Abdulhafiz
- Yang Wah
- Yanishev Alexey
- Yaqoob Sadia
- Yaqub Aimen
- Yasin Fawzi Hesham
- Younes Eman
- Youssef Hadeer M. S.
- Zahid Muhammad
- Zahid Sufian M.
- Zahran Ahmed A. A. A
- Zalf Kamal
- Zarin Mohammad
- Zawahra Aya
- Zayat Hussein
- Zayat Mohammed A.
- Zevallos-Quiroz Julio
- Zheng Helen
- Zivanovic Marko
- Zwain Yasir A.
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Importance Postoperative urinary retention (POUR) is a well-recognized complication of inguinal hernia repair (IHR). A variable incidence of POUR has previously been reported in this context, and contradictory evidence surrounds potential risk factors.Objective To ascertain the incidence of, explore risk factors for, and determine the health service outcomes of POUR following elective IHR.Design, Setting, and Participants The Retention of Urine After Inguinal Hernia Elective Repair (RETAINER I) study, an international, prospective cohort study, recruited participants between March 1 and October 31, 2021. This study was conducted across 209 centers in 32 countries in a consecutive sample of adult patients undergoing elective IHR.Exposure Open or minimally invasive IHR by any surgical technique, under local, neuraxial regional, or general anesthesia.Main Outcomes and Measures The primary outcome was the incidence of POUR following elective IHR. Secondary outcomes were perioperative risk factors, management, clinical consequences, and health service outcomes of POUR. A preoperative International Prostate Symptom Score was measured in male patients.Results In total, 4151 patients (3882 male and 269 female; median [IQR] age, 56 [43-68] years) were studied. Inguinal hernia repair was commenced via an open surgical approach in 82.2% of patients (n = 3414) and minimally invasive surgery in 17.8% (n = 737). The primary form of anesthesia was general in 40.9% of patients (n = 1696), neuraxial regional in 45.8% (n = 1902), and local in 10.7% (n = 446). Postoperative urinary retention occurred in 5.8% of male patients (n = 224), 2.97% of female patients (n = 8), and 9.5% (119 of 1252) of male patients aged 65 years or older. Risk factors for POUR after adjusted analyses included increasing age, anticholinergic medication, history of urinary retention, constipation, out-of-hours surgery, involvement of urinary bladder within the hernia, temporary intraoperative urethral catheterization, and increasing operative duration. Postoperative urinary retention was the primary reason for 27.8% of unplanned day-case surgery admissions (n = 74) and 51.8% of 30-day readmissions (n = 72).Conclusions The findings of this cohort study suggest that 1 in 17 male patients, 1 in 11 male patients aged 65 years or older, and 1 in 34 female patients may develop POUR following IHR. These findings could inform preoperative patient counseling. In addition, awareness of modifiable risk factors may help to identify patients at increased risk of POUR who may benefit from perioperative risk mitigation strategies
Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
- Author
- Abbas Ayman
- Abbood Ali Hashim
- Abdeen Basel
- Abdelaal Ahmed Samir
- Abdullah Nik A N
- Abdulwahed Eman
- Abelevich Alexander
- Abu Elnga Ahmed Nagm Eldin
- Abujamra Saleh
- Acar Nihan CoĆgun
- Afzal Asma
- Agalianos Christos
- Agapov Mikhail N
- Agostinelli Laura
- Ahmed Safia
- Aigner Felix
- Akyol Cihangir
- Al-Eryani Fatima
- Al-Juaifari Maytham A
- Al-Najami Issam
- Alanez-Saavedra Javier
- Albakry Rudaina
- Alcåzar Montero José A
- Alhardan Anas
- Alhisi Ahmed Jehad
- Ali Ahmed K
- Alkady Eithar
- Allmer Caterina
- Alonso Alfredo
- Alrayes Bourhan M H
- Alshareea Entisar
- Altomare Donato F
- Altrabulsi Amani
- Alvarez-Bautista Francisco E
- Amano Takahiro
- Amelung Femke J
- Anderin Kajsa
- Annicchiarico Alfredo
- Ansorena Yolanda Saralegui
- Antona Francisco Blanco
- Antonopoulou Maria-Ioanna
- Aprile Alessandra
- Armao Francesca T
- Arroyo Antonio
- Ashmore Daniel
- Atak Ä°brahim
- Atanasov Boyko
- Atici Semra Demirli
- Atienza Paula GonzĂĄlez
- Avanagh Dara O
- Avellaneda Nicolas
- Aversano Alessia
- Aydın Oguzhan
- Ayoub Kusay
- Azevedo Constança
- Baatrup Gunnar
- Baban Bayar
- Badiani Sarit
- Baili Efstratia
- Balalis Dimitrios
- Balci Bengi
- Balık Emre
- Ballabio Michele
- Baloyiannis Ioannis
- Barbero-Valenzuela Alejandro
- Bassyouni Ashoush Fouad M
- Bavikatte Akshay
- Bazaev Andrey
- Belev Nikolay
- Bellato Vittoria
- BeltrĂĄn de Heredia Juan P
- Belvedere Angela
- Benkabbou Amine
- BenÄurik Vladimir
- Bernal-Sprekelsen Juan C
- Berney Christophe
- Bethune Rob M
- Bhandari Santosh
- Bhat Sameer
- Binder Alf-Dorian
- Biondi Alberto
- Bisagni Pietro
- Bislenghi Gabriele
- Bissett Ian
- BiĆgin TAYFUN
- BjĂžrsum-Meyer Thomas
- Blas Juan L
- Bloemen Johanne G
- Boerma Evert-Jan G
- Bonito Alba Correa
- Borda Francisco Javier GarcĂa
- Borda-Arrizabalaga Nerea
- Bottazzoli Elisa I
- Boutall Adam
- Bouvy Nicole D
- BoĆŸiÄ Tajda KoĆĄir
- Brachini Gioia
- Bradley Nicholas
- Bremers Andreas J A
- Buchs Nicolas
- Buchwald Pamela
- Bulut Mehmet TĂŒrker
- Burger Jacobus W A
- Burghgraef Thijs A
- Busund Sondre
- Buzzi Gianluca
- BuÄra Dursun
- CalabrĂČ Marcello
- Calero-Lillo ArĂĄnzazu
- Calik Bulent
- Carbone Fabio
- Carreño-Villarreal Guillermo
- Carrie Augusto
- Carvello Michele
- Carvello Michele
- Catena Fausto
- Cengiz Fevzi
- Cerbo Daniele
- Ceretti Andrea P
- Chandio Ashfaq
- Chaoui Ahmed
- Charalabopoulos Alexandros
- Chaudhri Sanjay
- Chautems Roland
- Chawla Tabish
- Chawla Tabish
- Cholewa Hannia
- Christodoulidis Grigorios
- Chrysos Emmanuel
- CiftciEngin Aybar Ahmet B
- Cifuentes-Ródenas José A
- Cirillo Bruno
- Ciubotaru Cezar
- Ciubotaru Cezar
- Clerici Federico
- Coco Claudio
- Coetzee Emile
- Colak Elif
- Collard Maxime K
- Colucci Nicola
- ColĂĄs-Ruiz Enrique
- Connelly Tara M
- Consten Esther C J
- Consten Esther C J
- Corbellini Carlo
- Cotte Eddy
- Creemers Davy M J
- Crescentini Giacomo
- D'Agostino Luca
- D'Alimonte Lucrezia
- D'Hoore André
- da Costa Devesa Helena M
- da Silva Nigel
- Daester Silvio
- Darias IvĂĄn Soto
- Darlin Lotten
- Darwich Haitham
- Dattani Mit
- de Andrés Beatriz
- de Gheldere Charles
- de Graaf Eelco J R
- de Groot-van Veen Irene
- de Haan Jael
- de La Cruz Cuadrado Cristina
- de Lacy Francisco B
- de Manzoni Giovanni
- de Nes Lindsey C F
- de Paola Gilda
- de Pasqual Carlo A
- de Simone Belinda D
- de Vriendt Stefanie
- de Wilt Johannes H W
- Deeknah Abdulqudus
- Defoort Barbara
- deGiuli Maurizio
- Dekker Jan-Willem T
- Del Hoyo Aretxabala Izaskun
- Delrio Paolo
- Demirkiran Ahmet
- den Boer Frank
- Denost Quentin
- Dewulf Maxime
- deĂngelis Nicola
- di Cosmo Maria A
- Di Saverio Salomone
- Dimofte Gabriel-Mihail
- Dinaux Anne M
- Dittrich Luca S
- Diéguez Beatriz
- Docampo Iria Losada
- Dogan LĂŒtfi
- Doornebosch Pascal G
- Drozdov EvgeniyS
- Dudi-Venkata Nagendra N
- Dursun Ayberk
- Dziakova Jana
- DĂŒzgĂŒn ĂzgĂŒl
- Echaniz Garazi Elorza
- Echiguer Sabrillah
- Eduard Galliamov
- Egea Jorge GarcĂa
- El Muhtaseb Mohammad S
- El-Massoudi Youssef
- Elhadi Muhammed
- Elshennawy Eslam M
- Enriquez-Navascués José M
- Erdinc Kemal
- Eriksen Jacob D
- Ersryd Amanda L
- EscartĂn Jorge
- EspĂn-Basany Eloy
- Estaire-GĂłmez Mercedes
- EstefanĂa Diego
- Ewedah Moataz
- Fabbri NicolĂČ
- Fares Hala
- Farguell Jordi
- Faria Luis Queiroz
- Farnesi Francesca
- Fazzin Marta
- Feo Carlo V
- Ferenschild Floris T
- FernĂĄndez Cristina LĂłpez
- FernĂĄndez-Hevia MarĂa
- FernĂĄndez-Hevia MarĂa
- FernĂĄndez-Hurtado Ignacio
- FernĂĄndez-MartĂnez Daniel
- FernĂĄndez-MartĂnez Daniel
- Ferreira CĂĄtia
- Ferreira Rita Marques
- Ferrer RocĂo
- Filimonov Victor B
- Filipov Emil
- Fioravanti Emanuela
- Flamey Nicolas
- Florea Sabrina
- Folkesson Joakim
- Foppa Caterina
- Foppa Caterina
- Forgan Tim
- Fowler George E
- Frasson Matteo
- Frivold Tone
- Frontali Alice
- Fujiwara Hajime
- Futaba Kaori
- Gaard Maria
- Gadan Soran
- Galleano Raffaele
- Gallo Gaetano
- GarcĂa-FlĂłrez Luis J
- GarcĂa-FlĂłrez Luis J
- Gareb Fahed
- Garmanova Tatiana
- Garulli Gianluca
- Gecim Ibrahim E
- Geitenbeek Ritch
- George Sarah
- Ghazouani Omar
- Ghignone Federico
- Ghmagh Reem
- Gialamas Eleftherios
- Gielis Manuel
- Gil Lopez Jose M
- Giuffrida Mario
- Golshani Parisa
- Gonzalez Ricardo
- GonzĂĄlvez Paula
- Goutard Claire-Angéline
- Grass Julia-Kristin
- Graure Giorgiana M
- Gregussen Hilde
- Greijdanus Nynke G
- Gribnev Petar
- Grosek Jan
- Grossi Ugo
- Grotenhuis Brechtje A
- GrĂŒter Alexander A J
- Guel-Klein Safak
- Guenin Marc-Olivier
- Gurjar Shashank
- GĂłmez Tania
- GĂłmez-Abril Segundo Ă
- GĂłmez-Jurado MarĂa J
- GöbĂŒt HĂŒseyin
- GĂŒnenç ErĆan
- GĂŒrtler Thomas
- GĂŒzel Melek
- Haberal Elifcan
- Haddad Anis
- Hajjaj Baraa Nabil
- Hamdan Alaa
- Hamid Hytham K S
- Hammoodi Hayder
- Hani Mohammad Bani
- Hannink Gerjon
- Hasan Bassam
- Hassan Naya
- Hassan Soha Y
- Havenga Klaas
- Hazen Sanne J A
- Heemskerk Jeroen
- Heesink Vera
- Heidsma Charlotte M
- Heijnen Bob H M
- Herman Ayesiga
- HernĂĄndez Miguel
- Herrero Eduardo Ferrero
- Hess Gabriel F
- Ho Man-Fung
- Ho Yiu M
- Hoff Christiaan
- Hol Jeroen C
- Hollington Paul
- Holman Fabian A
- Hompes Roel
- Hoogteijling Tijs J
- Hulshof Lorenzo G W L
- Hussein Mohamed
- Iacomino Alessandro
- Ibrahim Aini F
- Ismail Razif
- Ivanov Tsvetomir
- Iversen Lene H
- Jadid Kaveh Dehlaghi
- Jakubauskas Matas
- Jakubauskiene Lina
- Jangmalm Staffan
- Janssen Paul T J
- Jou-Valencia Daniela
- Julaihi Rokayah
- Jutesten Henrik
- Kacem Montasser
- Kader Rawaz
- Kamer Erdinc
- Kapadia Raj
- Kara Yasin
- Karamanliev Martin
- Karavokyros Ioannis
- Karmi Fahed
- Karsten Tom
- Karydakis Lysandros
- Kaya Tayfun
- Kelly Michael E
- Keskin Metin
- Ketelaers Stijn H J
- Khader Ahmed A E
- Khedr Gehan Abd Elatti
- Koc Mehmet A
- Koemans Willem J
- Konishi Tsuyoshi
- Korkolis Dimitrios
- Kostromitskiy Dmitriy N
- Kozan Ramazan
- KoĆĄir Jurij A
- Kraft Miquel
- Krastev Panche
- Krohn Nina
- Kroon Hidde M
- Kryzauskas Marius
- Kulle Cemil B
- Kulle Cemil B
- Kusters Miranda
- Kynaston James
- Lacy Antonio M
- Lambrechts Anton
- Lamme Bas
- Lamparelli Michael
- Lantone Giuliano
- Lapolla Pierfrancesco
- Larcinese Antonella
- Larkin John O
- Larkin John O
- Larsson Per-Anders
- Latkauskas Tadas
- Lauka Lelde
- Leeuwenburgh Marjolein M
- Lefevre Jérémie H
- Leijtens Jeroen W A
- Leung Edmund
- LeventoÄlu Sezai
- Lindqvist Ebba
- Liu Jianliang
- Longhi Marco
- Lorenzon Laura
- Lorusso Leonardo
- Losada Manuel
- Lucchi Andrea
- LuncÄ Sorinel
- Lutfi Hamid
- Lydrup Marie-Louise
- LĂłpez-Lara Manuel
- LĂłpez-RodrĂguez-Arias Francisco
- Macau Florin
- Machackova Maria
- Maghrebi Houcine
- Majbar Mohammed A
- Mak Tony Wing-Chung
- Manatakis Dimitrios
- Mansour Ali
- Manzo Carlo A
- Marchegiani Francesco
- Marcos Elena Bermejo
- Mariani NicolĂČ M
- Marinelli Andreas
- Markaryan Daniil G
- Maroli Annalisa
- Martins SĂłnia Fortuna
- MartĂnek LubomĂr
- MartĂnez MarĂa Labalde
- MartĂnez-Pinedo Carlos
- Maslyankov Svilen
- Massey Lisa
- Matthiessen Peter
- Mattioni Laura A
- McCormick Paul H
- McCullough Peter
- Medina Quintana Rita E
- Mehigan Brian J
- Melling Nathaniel
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- Mendes Ana Filipa Dias
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- Mikalauskas Saulius
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- Mitteregger Martin
- Miu Victor
- Moctezuma-VelĂĄzquez Paulina
- Mohamed Abudi
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- Monib Fatma A
- Monson John
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- Morales Bernaldo de QuirĂłs Javier T
- Morgan Matthew
- Msherghi Ahmed A
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- Muratore Andrea
- Muriel Jorge Sancho
- Musters Gijsbert D
- Muñoz-Collado Salvador
- MuÈinÄ Ana-Maria
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- Nespoli Luca
- Ng Simon Siu-Man
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- Nichita Vladimir-Ion
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- Pantoja Pachajoa Diana A
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- Petropolou Thalia
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- Picciariello Arcangelo
- Picone Emanuele
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- Pire-Abaitua Gerardo
- Pirozzolo Giovanni
- PiyadeoÄlu Deniz
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- Rosman Camiel
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- Scabini Stefano
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- Schultz Johannes K
- Sebai Amine
- Sebastian Boby
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- Seitinger Gerald
- SemiĂŁo Miguel
- Septiem Javier GarcĂa
- Serralta Daniel
- Shaban Mohamed
- Shaikh Shafaque
- Shapiro Joël
- Siaw Oliver
- Sıbıç Osman
- Sica Giuseppe
- Sietses Colin
- Singh Baljit
- Singh Nirbhaibir
- Singh-Ranger Deepak
- Sinibaldi Giovanni
- Siragusa Leandro
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- Syllaios Athanasios
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- SĂĄnchez Teresa Rubio
- Sånchez-Guillén Luis
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- Tababa Osama W E
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- Tejedor Patricia
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- Toorenvliet Boudewijn R
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- Toso Christian
- Tsimogiannis Konstantinos
- Tuynmann Jurriaan B
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- Ugolini Giampaolo
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- van den Hengel Berber
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- Verdaasdonk Emiel G G
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- Villar Ăscar GarcĂa
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- von FlĂŒe Markus
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- Vosbeek Noortje
- Vuagniaux Aurélie
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- Waqar Usama
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- Wong Michael P K
- Woods Kayla
- Xenaki Sofia
- Xynos Evangelos
- Yalkın Ămer
- Yanishev Alexey
- YĂŒksel Osman
- Zabala JesĂșs GĂłmez
- Zakaria Andee D
- Zakaria Zaidi
- Zanini Nicola
- Zanus Giacomo
- Zazo Aya
- Zazo Rama
- Zucchella Martino
- ZukanoviÄ Goran
- Zwakman Marije
- Ăakır Murat
- Ăzata Ä°brahim H
- ĂzgĂŒr Ä°lker
- Ăzkan Ămer Faruk
- ĂlgĂŒr Hanife Ćeyda
- Ć antak Goran
- Ć imleĆĄa Damir
- Ć lenfuktas Vygintas
- Ćœilinskas Justas
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Objective:To develop and validate a prediction model (STOMA score) for 1-year stoma-free survival in patients with rectal cancer (RC) with anastomotic leakage (AL).Background:AL after RC resection often results in a permanent stoma.Methods:This international retrospective cohort study (TENTACLE-Rectum) encompassed 216 participating centres and included patients who developed AL after RC surgery between 2014 and 2018. Clinically relevant predictors for 1-year stoma-free survival were included in uni and multivariable logistic regression models. The STOMA score was developed and internally validated in a cohort of patients operated between 2014 and 2017, with subsequent temporal validation in a 2018 cohort. The discriminative power and calibration of the models' performance were evaluated.Results:This study included 2499 patients with AL, 1954 in the development cohort and 545 in the validation cohort. Baseline characteristics were comparable. One-year stoma-free survival was 45.0% in the development cohort and 43.7% in the validation cohort. The following predictors were included in the STOMA score: sex, age, American Society of Anestesiologist classification, body mass index, clinical M-disease, neoadjuvant therapy, abdominal and transanal approach, primary defunctioning stoma, multivisceral resection, clinical setting in which AL was diagnosed, postoperative day of AL diagnosis, abdominal contamination, anastomotic defect circumference, bowel wall ischemia, anastomotic fistula, retraction, and reactivation leakage. The STOMA score showed good discrimination and calibration (c-index: 0.71, 95% CI: 0.66-0.76).Conclusions:The STOMA score consists of 18 clinically relevant factors and estimates the individual risk for 1-year stoma-free survival in patients with AL after RC surgery, which may improve patient counseling and give guidance when analyzing the efficacy of different treatment strategies in future studies
Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients
- Author
- Aalbers Arend G.J.
- Abbas Ayman
- Abbood Ali Hashim
- Abdeen Basel
- Abdelaal Ahmed Samir
- Abdullah Nik A.N.
- Abdulwahed Eman
- Abelevich Alexander
- Abujamra Saleh
- Acar Nihan CoĆgun
- Afzal Asma
- Agalianos Christos
- Agapov Mikhail N.
- Agostinelli Laura
- Ahmed Nagm Eldin Abu Elnga
- Ahmed Safia
- Aigner Felix
- Akyol Cihangir
- Al-Eryani Fatima
- Al-Juaifari Maytham A.
- Al-Najami Issam
- Alanez-Saavedra Javier
- Albakry Rudaina
- Alhardan Anas
- Alhisi Ahmed Jehad
- Ali Ahmed K.
- Alkady Eithar
- Allmer Caterina
- Alonso Alfredo
- Alrayes Bourhan M.H.
- Alshareea Entisar
- Altomare Donato F.
- Altrabulsi Amani
- Alvarez-Bautista Francisco E.
- Amano Takahiro
- Amelung Femke J.
- Anderin Kajsa
- Annicchiarico Alfredo
- Ansorena Yolanda Saralegui
- Antona Francisco Blanco
- Antonopoulou Maria-Ioanna
- Aprile Alessandra
- Aranda MarĂa J. Pizarro
- Aretxabala Izaskun del Hoyo
- Armao Francesca T.
- Arroyo Antonio
- Ashmore Daniel
- Ashoush Fouad M. Bassyouni
- Atak Ä°brahim
- Atanasov Boyko
- Atici Semra Demirli
- Atienza Paula GonzĂĄlez
- Avanagh Dara O.
- Avellaneda Nicolas
- Aversano Alessia
- Aybar Ahmet B. CiftciEngin
- Aydin Oguzhan
- Ayoub Kusay
- Azevedo Constanca
- Baatrup Gunnar
- Baban Bayar
- Badiani Sarit
- Bahadoer Renu R.
- Baili Efstratia
- Balalis Dimitrios
- Balci Bengi
- Balik Emre
- Ballabio Michele
- Baloyiannis Ioannis
- Barbero-Valenzuela Alejandro
- Bavikatte Akshay
- Bazaev Andrey
- Belev Nikolay
- Bellato Vittoria
- BeltrĂĄn de Heredia Juan P.
- Belvedere Angela
- Benkabbou Amine
- BenÄurik Vladimir
- Bernal-Sprekelsen Juan C.
- Berney Christophe
- Bethune Rob M.
- Bhandari Santosh
- Bhat Sameer
- Binder Alf-Dorian
- Biondi Alberto
- Bisagni Pietro
- Bislenghi Gabriele
- Bissett Ian
- BiĆgin Tayfun
- Bjorsum-Meyer Thomas
- Blas Juan L.
- Bloemen Johanne G.
- Boerma Evert-Jan G.
- Bonito Alba Correa
- Borda Francisco Javier GarcĂa
- Borda-Arrizabalaga Nerea
- Bottazzoli Elisa I.
- Boutall Adam
- Bouvy Nicole D.
- BoĆŸiÄ Tajda KoĆĄir
- Brachini Gioia
- Bradley Nicholas
- Bremers Andreas J.A.
- Buchs Nicolas
- Buchwald Pamela
- Bulut Mehmet Turker
- Burger Jacobus W.A.
- Burghgraef Thijs A.
- Busund Sondre
- Buzzi Gianluca
- BuÄra Dursun
- Calabro Marcello
- Calero-Lillo ArĂĄnzazu
- Calik Bulent
- Carbone Fabio
- Carreño-Villarreal Guillermo
- Carrie Augusto
- Carvello Michele
- Carvello Michele
- Catena Fausto
- Cengiz Fevzi
- Cerbo Daniele
- Ceretti Andrea P.
- Chandio Ashfaq
- Chaoui Ahmed
- Charalabopoulos Alexandros
- Chaudhri Sanjay
- Chautems Roland
- Chawla Tabish
- Chawla Tabish
- Cholewa Hannia
- Christodoulidis Grigorios
- Chrysos Emmanuel
- Cifuentes-Ródenas José A.
- Cirillo Bruno
- Ciubotaru Cezar
- Ciubotaru Cezar
- Clerici Federico
- Coco Claudio
- Coetzee Emile
- Colak Elif
- Collard Maxime K.
- Colucci Nicola
- ColĂĄs-Ruiz Enrique
- Connelly Tara M.
- Consten Esther C.J.
- Consten Esther C.J.
- Corbellini Carlo
- Cotte Eddy
- Creemers Davy M.J.
- Crescentini Giacomo
- D'Agostino Luca
- D'Alimonte Lucrezia
- D'Hoore André
- da Costa Devesa Helena M.
- da Silva Nigel
- Daester Silvio
- Darias IvĂĄn Soto
- Darlin Lotten
- Darwich Haitham
- Dattani Mit
- de Andrés Beatriz
- de Gheldere Charles
- de Graaf Eelco J.R.
- de Groot-Van Veen Irene
- de Haan Jael
- de La Cruz Cuadrado Cristina
- de Lacy F. Borja
- de Manzoni Giovanni
- de Nes Lindsey C.F.
- de Paola Gilda
- de Pasqual Carlo A.
- de Simone Belinda D.
- de Vriendt Stefanie
- de Wilt Johannes H.W.
- de Ăngelis Nicola
- Deeknah Abdulqudus
- Defoort Barbara
- deGiuli Maurizio
- Dekker Jan-Willem T.
- Delrio Paolo
- Demirkiran Ahmet
- den Boer Frank
- Denost Quentin
- Dewulf Maxime
- di Cosmo Maria A.
- Di Saverio Salomone
- Dimofte Gabriel-Mihail
- Dinaux Anne M.
- Dittrich Luca S.
- Diéguez Beatriz
- Docampo Iria Losada
- Dogan Lutfi
- Doornebosch Pascal G.
- Drozdov Evgeniy S.
- Dudi-Venkata Nagendra N.
- Dursun Ayberk
- Duzgun Ozgul
- Dziakova Jana
- DĂez-Alonso Manuel
- Echaniz Garazi Elorza
- Echiguer Sabrillah
- Eduard Galliamov
- Egea Jorge GarcĂa
- el Muhtaseb Mohammad S.
- El-Massoudi Youssef
- Elhadi Muhammed
- Elshennawy Eslam M.
- Enriquez-Navascués José M.
- Erdinc Kemal
- Eriksen Jacob D.
- Ersryd Amanda L.
- EscartĂn Jorge
- EspĂn-Basany Eloy
- Estaire-GĂłmez Mercedes
- Estefania Diego
- Ewedah Moataz
- Fabbri Nicolo
- Fares Hala
- Farguell Jordi
- Faria Luis Queiroz
- Farnesi Francesca
- Fazzin Marta
- Feo Carlo V.
- Ferenschild Floris T.
- FernĂĄndez C.L.
- FernĂĄndez-Hevia MarĂa
- FernĂĄndez-Hurtado Ignacio
- FernĂĄndez-MartĂnez Daniel
- Ferreira Catia
- Ferreira Rita Marques
- Ferrer RocĂo
- Filimonov Victor B.
- Filipov Emil
- Fioravanti Emanuela
- Flamey Nicolas
- Florea Sabrina
- Folkesson Joakim
- Foppa Caterina
- Foppa Caterina
- Forgan Tim
- Fowler George E.
- Frasson Matteo
- Frivold Tone
- Frontali Alice
- Fujiwara Hajime
- Futaba Kaori
- Gaard Maria
- Gadan Soran
- Galleano Raffaele
- Gallo Gaetano
- GarcĂa-FlĂłrez Luis J.
- Gareb Fahed
- Garmanova Tatiana
- Garulli Gianluca
- Gecim Ibrahim E.
- Geitenbeek Ritch
- George Sarah
- Ghazouani Omar
- Ghignone Federico
- Ghmagh Reem
- Gialamas Eleftherios
- Gielis Manuel
- Giuffrida Mario
- Gobut Huseyin
- Golshani Parisa
- Gonzalez Ricardo
- GonzĂĄlvez Paula
- Goutard Claire-Angéline
- Grass Julia-Kristin
- Graure Giorgiana M.
- Gregussen Hilde
- Greijdanus Nynke G.
- Gribnev Petar
- Grosek Jan
- Grossi Ugo
- Grotenhuis Brechtje A.
- Gruter Alexander A.J.
- Guel-Klein Safak
- Guenin Marc-Olivier
- Gunenc ErĆan
- Gurjar Shashank
- Gurtler Thomas
- Guzel Melek
- GĂłmez Tania
- GĂłmez-Abril Segundo Ă.
- GĂłmez-Jurado MarĂa J.
- Haberal Elifcan
- Haddad Anis
- Hajjaj Baraa Nabil
- Hamdan Alaa
- Hamid Hytham K.S.
- Hammoodi Hayder
- Hani Mohammad Bani
- Hannink Gerjon
- Hasan Bassam
- Hassan Naya
- Hassan Soha Y.
- Havenga Klaas
- Hazen Sanne J.A.
- Heemskerk Jeroen
- Heesink Vera
- Heidsma Charlotte M.
- Heijnen Bob H.M.
- Herman Ayesiga
- HernĂĄndez Miguel
- Herrero Eduardo Ferrero
- Hess Gabriel F.
- Ho Man-Fung
- Ho Yiu M.
- Hoff Christiaan
- Hol Jeroen C.
- Hollington Paul
- Holman Fabian A.
- Hompes Roel
- Hoogteijling Tijs J.
- Huguet José M. Muguerza
- Hulshof Lorenzo G.W.L.
- Hussein Mohamed
- Iacomino Alessandro
- Ibrahim Aini F.
- Ismail Razif
- Ivanov Tsvetomir
- Iversen Lene H.
- Jadid Kaveh Dehlaghi
- Jakubauskas Matas
- Jakubauskiene Lina
- Jangmalm Staffan
- Janssen Paul T.J.
- Jarimba Aldo M. Rodrigues
- Jou-Valencia Daniela
- Julaihi Rokayah
- Jutesten Henrik
- Kacem Montasser
- Kader Rawaz
- Kamer Erdinc
- Kapadia Raj
- Kara Yasin
- Karamanliev Martin
- Karavokyros Ioannis
- Karmi Fahed
- Karsten Tom
- Karydakis Lysandros
- Kaya Tayfun
- Kelly Michael E.
- Keskin Metin
- Ketelaers Stijn H.J.
- Khader Ahmed A.E.
- Khedr Gehan Abd Elatti
- Koc Mehmet A.
- Koemans Willem J.
- Konishi Tsuyoshi
- Korkolis Dimitrios
- Kostromitskiy Dmitriy N.
- Kozan Ramazan
- KoĆĄir Jurij A.
- Kraft Miquel
- Krastev Panche
- Krohn Nina
- Kroon Hidde M.
- Kryzauskas Marius
- Kulle Cemil B.
- Kulle Cemil B.
- Kusters Miranda
- Kynaston James
- La Terra Antonio
- Lacy Antonio M.
- Lambrechts Anton
- Lamme Bas
- Lamparelli Michael
- Lantone Giuliano
- Lapolla Pierfrancesco
- Lara Juan E. SĂĄnchez
- Larcinese Antonella
- Larkin John O.
- Larkin John O.
- Larsson Per-Anders
- Latkauskas Tadas
- Lauka Lelde
- Leeuwenburgh Marjolein M.
- Lefevre Jérémie H.
- Leijtens Jeroen W.A.
- Leung Edmund
- LeventoÄlu Sezai
- Lindqvist Ebba
- Liu Jianliang
- Longhi Marco
- Lopez Jose M. Gil
- Lorenzon Laura
- Lorusso Leonardo
- Losada Manuel
- Lucchi Andrea
- LuncÄ Sorinel
- Lutfi Hamid
- Lydrup Marie-Louise
- LĂłpez-Lara Manuel
- LĂłpez-RodrĂguez-Arias Francisco
- Macau Florin
- Machackova Maria
- Maghrebi Houcine
- Majbar Mohammed A.
- Mak Tony Wing-Chung
- Manatakis Dimitrios
- Mansour Ali
- Manzo Carlo A.
- Marchegiani Francesco
- Marcos Elena Bermejo
- Mariani NicolĂČ M.
- Marinelli Andreas
- Markaryan Daniil G.
- Maroli Annalisa
- Marques Sonia M. Ribeiro
- Martinek Lubomir
- Martins Sonia Fortuna
- MartĂnez MarĂa Labalde
- MartĂnez-Pinedo Carlos
- Maslyankov Svilen
- Massey Lisa
- Matthiessen Peter
- Mattioni Laura A.
- MatĂas-GarcĂa BelĂ©n
- McCormick Paul H.
- McCullough Peter
- Mehigan Brian J.
- Melling Nathaniel
- Melnikov Andrey A.
- Mendes Ana Filipa Dias
- Mendoza-Moreno Fernando
- Meroni Paola
- Mia Imraan
- Mikalauskas Saulius
- Mingoli Andrea
- Mishra Amitabh
- Mitteregger Martin
- Miu Victor
- Moctezuma-VelĂĄzquez Paulina
- Mohamed Abudi
- Mohsine Raouf
- Monib Fatma A.
- Monson John
- Montero José A. Alcåzar
- Montroni Isacco
- Morales Bernaldo de QuirĂłs Javier T.
- Morgan Matthew
- Msherghi Ahmed A.
- Mueller Simone
- Mugla Naser
- Mukherjee Tanmoy
- Muratore Andrea
- Muriel Jorge Sancho
- Musters Gijsbert D.
- Muñoz-Collado Salvador
- MuĆinÄ Ana-Maria
- MĂnguez-Ruiz GermĂĄn
- Nair Gavin
- Navarro-SĂĄnchez Antonio
- Neary Peter
- Negoi Ionut
- Negoita Valentina M.
- Nespoli Luca
- Ng Simon Siuman
- Niazi Ammar
- Nichita Vladimir-Ion
- Niemer Quirine
- Nieto-Moreno Elena
- Nilsson Karl
- Nonner Joost
- Novello Simone
- Nygren Jonas
- O'Grady Greg
- Obihara Ndidi J.
- Oldani Massimo
- Oliveira Antonio
- Oosterling Steven J.
- Opocher Enrico
- Osborne Laura
- Ozata Ä°brahim H.
- Ozgur Ä°lker
- Ozkan Omer Faruk
- Pachajoa Diana A. Pantoja
- Palini Gian M.
- Panel Nathalie
- Panis Yves
- Parc Yann
- Parise Cristiano
- Park Jennifer M.
- Parodi Matias
- Pasini Francesco
- Pasini Franceso
- Passuello Nicola
- Pattyn Paul
- Pavlov Vasil
- Peeters Koen C.M.J.
- Pellino Gianluca
- Pennings Alexander J.
- Pereira Ricardo
- Perez Daniel
- Perez Rodrigo O.
- Perivoliotis Konstantinos
- Perrone Gennaro
- Persiani Roberto
- Pesce Antonio
- Petropolou Thalia
- Pezzuto Roberto
- Picciariello Arcangelo
- Picone Emanuele
- Pikuniene Ingrida
- Pinto Francisca Lima
- Pire-Abaitua Gerardo
- Pirozzolo Giovanni
- PiyadeoÄlu Deniz
- Plastiras Aris
- Pletinckx Pieter
- Polat Fatih
- Polle Sebastiaan W.
- Polydorou Adreas
- Porta Andrea
- Poskus Tomas
- Pratschke Johann
- Pringle Heather C.M.
- Puca Lucia
- Pucciarelli Salvatore
- Qandeel Mahmoud W.M.
- Quintana Rita E. Medina
- Quiroga Ignacio Bodega
- Quiroga-ValcĂĄrcel Ana
- Rabadi Alexander
- Ramboiu Stefan Patrascu Sandu D.
- Ramsay George
- Rani Pallavi
- Rani Pallavi
- Rauf Hareem
- Rauf Hareem
- Recordare Alfonso
- Reddavid Rossella
- Rega Daniela
- Reudink Muriël
- Riedl Peter
- Riis Rolf
- Ripoli Maria Cristina
- Ris Frederic
- Rizzo Gianluca
- RoatÄ Cristian-Ene
- Rodimov Sergey V.
- RodrĂguez Carlos SĂĄez-Cazallas
- RodrĂguez-Infante Antonio
- Romano Angela
- Rompou Aliki
- Roos Daphne
- Roscio Francesco
- Rosman Camiel
- Rotholtz Nicolas
- Rottoli Matteo
- Ruiz Hernan
- Runau Francois
- RutegÄrd Martin
- Rutten Harm J.T.
- RuĂz-GarcĂa Pablo
- Ryan Jessica
- Rydbeck Daniel
- Saad Ahmad
- Sacchi Matteo M.
- Sacchi Matteo M.
- Sainz-HernĂĄndez Juan C.
- Salgado-Nesme Noel
- Salomon Mario
- Sambucci Daniele
- Sammarco Giuseppe
- Sammour Tarik
- Sampietro Gianluca M.
- Samsa Mehmet Veysi
- Santacruz Carlos CerdĂĄn
- Santillan Mateo
- Santoro Giulio A.
- Sari Ahmet Can
- Sarmah Panchali
- Sarveswaran Janahan
- Sauvain Marc-Olivier
- Scabini Stefano
- Scheurink Lieke
- Schizas Dimitrios
- Schultz Johannes K.
- Sebai Amine
- Sebastian Boby
- Segelman Josefin
- Seitinger Gerald
- Semiao Miguel
- Septiem Javier GarcĂa
- Serralta Daniel
- Shaban Mohamed
- Shaikh Shafaque
- Shapiro Joël
- Siaw Oliver
- Sibiç Osman
- Sica Giuseppe
- Sietses Colin
- Singh Baljit
- Singh Nirbhaibir
- Singh-Ranger Deepak
- Sinibaldi Giovanni
- Siragusa Leandro
- Sivrikoz Emre
- Sjo Ole H.
- Sjostrom Olle
- Skrovina Matej
- Sköldberg Filip
- Slavchev Mihail
- Slooter Gerrit D.
- Smeeing Diederik P.J.
- Sokmen Selman
- Sokolov Manol
- Soler-Silva Ălvaro
- Solomon Michael
- Soriero Domenico
- Souadka Amine
- Spinelli Antonino
- Spinelli Antonino
- Spolverato Gaya
- Staffan Maria
- Stefanescu Victor
- Steller Ernst J.
- Stienstra Roxane M.
- Stoica Bogdan
- Stoica Bogdan
- Suchkov Igor A.
- Sultan Hytham
- Surlin Valeriu M.
- SuĂĄrez Marta Castro
- SuĂĄrez-SĂĄnchez Aida
- Syllaios Athanasios
- SĂĄnchez Teresa Rubio
- Sånchez-Guillén Luis
- Tababa Osama W.E.
- Taha-Mehlitz Stephanie
- Talboom Kevin
- Talsma Aaldert K.
- Tamelis Algimantas
- Tamini NicolĂČ
- Tanase Ioan
- Tanis Pieter J.
- Tantoura Mohammad
- Tanzanu Marta
- Tasende-Presedo Marta M.
- Tasis Nikolaos
- Taverne Sophie B.M.
- Tejedor Patricia
- Teras Juri
- Teras Roland M.
- Tiefenthal Marit
- Tomasicchio Giovanni
- TomaĆŸiÄ AleĆĄ
- Tonchev Pencho
- Toorenvliet Boudewijn R.
- Torres MarĂa T.
- Toso Christian
- Tsimogiannis Konstantinos
- Tuynmann Jurriaan B.
- Tzovaras George
- Ubels Sander
- Ugolini Giampaolo
- Ulgur Hanife Ćeyda
- Uluk Deniz
- Vailas Michail
- Vailati Bruna B.
- van Dalsen Annette D.
- van den Broek Nathalie E.J.
- van den Hengel Berber
- van der Burg Sjirk
- van der Zijden CharlĂšne J.
- van Gerven Pieter
- van Kessel Charlotte S.
- van Praagh Jasper B.
- van Schaik Ted G.
- van Westreenen Hendrik L.
- van Workum Frans
- Vanclooster Patrick
- Vansteenbrugge Louis
- Vasile Mihai
- Venianaki Maria
- Verdaasdonk Emiel G.G.
- Vergara-FernĂĄndez Omar
- Vermaas Maarten
- Verstappen Sonja
- Vignotto Chiara
- Villar Ăscar GarcĂa
- Vittori Laura
- Vles Wouter J.
- von Flue Markus
- Voron Thibault
- Vosbeek Noortje
- Vuagniaux Aurelie
- VĂĄzquez Andrea
- Waqar Usama
- Waqar Usama
- Ward Nicholas
- Warden Claire
- Westerterp Marinke
- Wienholts Kiedo
- Wiering Bastiaan
- Wijma Allard G.
- Wildeboer Aurelia C.L.
- Wolthuis Albert
- Wong Michael P.K.
- Woods Kayla
- Xenaki Sofia
- Xynos Evangelos
- Yalkin Omer
- Yanishev Alexey
- Yuksel Osman
- Zabala JesĂșs GĂłmez
- Zakaria Andee D.
- Zakaria Zaidi
- Zanini Nicola
- Zanus Giacomo
- Zazo Aya
- Zazo Rama
- Zucchella Martino
- ZukanoviÄ Goran
- Zwakman Marije
- Ăakir Murat
- ÄosiÄ Jurica
- Ć antak Goran
- Ć imleĆĄa Damir
- Ć lenfuktas Vygintas
- Ćœilinskas Justas
- Publication venue
- Publication date
- 01/12/2023
- Field of study
Background: The optimal treatment of anastomotic leak after rectal cancer resection is unclear. This worldwide cohort study aimed to provide an overview of four treatment strategies applied. Methods: Patients from 216 centres and 45 countries with anastomotic leak after rectal cancer resection between 2014 and 2018 were included. Treatment was categorized as salvage surgery, faecal diversion with passive or active (vacuum) drainage, and no primary/secondary faecal diversion. The primary outcome was 1-year stoma-free survival. In addition, passive and active drainage were compared using propensity score matching (2: 1). Results: Of 2470 evaluable patients, 388 (16.0 per cent) underwent salvage surgery, 1524 (62.0 per cent) passive drainage, 278 (11.0 per cent) active drainage, and 280 (11.0 per cent) had no faecal diversion. One-year stoma-free survival rates were 13.7, 48.3, 48.2, and 65.4 per cent respectively. Propensity score matching resulted in 556 patients with passive and 278 with active drainage. There was no statistically significant difference between these groups in 1-year stoma-free survival (OR 0.95, 95 per cent c.i. 0.66 to 1.33), with a risk difference of -1.1 (95 per cent c.i. -9.0 to 7.0) per cent. After active drainage, more patients required secondary salvage surgery (OR 2.32, 1.49 to 3.59), prolonged hospital admission (an additional 6 (95 per cent c.i. 2 to 10) days), and ICU admission (OR 1.41, 1.02 to 1.94). Mean duration of leak healing did not differ significantly (an additional 12 (-28 to 52) days). Conclusion: Primary salvage surgery or omission of faecal diversion likely correspond to the most severe and least severe leaks respectively. In patients with diverted leaks, stoma-free survival did not differ statistically between passive and active drainage, although the increased risk of secondary salvage surgery and ICU admission suggests residual confounding
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- AbellĂĄn Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
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- Hooper Richard L
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- Zayakov Georgi
- Zaycev Andrey
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- Zazo Rama
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- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
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- Ăngelo Miguel Duarte
- ĂSullivan Sara Nuñez
- Ăzçelik Mehmet Faik
- Äoza Ivo
- Ćanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)