Cryoglobulinemia and hepatitis C virus

The review presents recent data on cryoglobulinemiaassociated with a hepatitis C virus: prevalence, pathogenesis, clinical manifestations, laboratory diagnostics, approaches to therapy

New trophic classification of wood-destroying fungi the case of community of pathogenic polypore fungi types on Pedunculate oak

Based on the generalization of experimental data obtained during the practical study of the trophic specialization of wood-destroying fungi from the commonness of PTH on oak in the oak forests of the south-west of the Central Russian Upland, a new ecotrophic classification has been developed, including the following groups of wood-destroying fungi: biotrophic pathogens, saprotrophic pathogens, pathogenic saprotrophs, non-pathogenic saprotroph

Trans-species relation in communities of pathogenic Polyporaceae on pedunculate oak Quercus robur L

In the process of research phytopathological and mycocenological methods were used As a result of the research, real trans-species relation were revealed in the most common and frequently occurring types of PPF on oak within various communities: Mutually positive type relationships based on the proto-operation were found between Laetiporus sulphureus and Fistulina hepatica. Neutral type relationships were found in between Fistulina hepatica and Fomitiporia robusta, Laetiporus sulphureus and Fomitiporia robust

Opportunities for the analysis of the spatial ecological structure of the mycobiota of macromycetes of a natural-territorial entity (the case of the Botanical Garden of Belgorod University, Belgorod, Russia)

On the basis of direct observations, the general principles of the organization of the mycobiota of the macromycetes of the natural-territorial formation "Botanical Garden" of Belgorod State University (Belgorod, Russian Federation) have been clarified. Based on the clarified principles, a scheme of their spatial ecological organization has been constructed: mycobiota - mycohore (mycocenosis, mycoaggregation) - mycosinium-3 - mycocenocells - mycocell. The obtained results can be used to study the spatial ecological organization of mycobiota macromycetes of other natural-territorial formation

Cryopreservation of raspberry cultivar accessions bred in Russia from the VIR <i>in vitro</i> collection

Cryobanks use plant cryocollections for long-term preservation of crops which cannot be preserved in seed collections. These are vegetatively propagated crops, accessions of species which form either a small amount of seeds, or recalcitrant seeds. Shoot tips (apexes) of in vitro plants are used for cryopreservation for most berry crops, therefore maintenance of in vitro collections is very important. The VIR in vitro collection includes 150 accessions of Rubus L. species, 85 of them are raspberry cultivars, 59 of which were bred in Russia. These cultivars reflect a wide ecogeographic diversity. Among them, there are raspberry cultivars created at the end of the 19th – first half of the 20th centuries, including cultivars bred by I.V. Michurin and by the pioneer of northern horticulture V.V. Spirin. More than half of national raspberry varieties (33) are listed in the State Register for Selection Achievements Admitted for Usage. Raspberry cultivars from Russian breeding programs have a very limited representation in foreign genebanks. The first aim of the present work was cryopreservation of mostly folk and old Russian raspberry cultivars received by VIR from 1925 till 1950 and their transfer into the cryobank. The second aim of the work was to monitor post-cryogenic regeneration of raspberry cultivars transferred to the cryobank earlier. A modified protocol of the droplet vitrification method by “DV-biotech” was used for cryopreservation of shoot tips of in vitro plants of 10 raspberry cultivars (7 of which are folk and old Russian ones) from the VIR in vitro collection. Post-cryogenic regeneration was evaluated for 17 raspberry cultivars preserved in the cryobank from one to five years. Ten raspberry cultivars (900 apexes) with an average mean post-cryoregenic regeneration value of 38.2±3.0% determined in control tests, were placed in the cryobank for long-term storage. A statistically significant effect of the genotype on the viability of explants after cryopreservation was noted, while the post-cryogenic regeneration was genotype insensitive. Additionally, levels of post-cryogenic regeneration were evaluated for 17 raspberry cultivars (296 apexes) preserved in the cryobank from one to five years. Post-cryogenic regeneration within the 20-70% range was displayed by four raspberry cultivars preserved in the cryobank for one year, and for 8 cultivars conserved there from three to five years post-cryogenic regeneration was within the 10-50% range. According to the results of monitoring, regeneration displayed by 12 raspberry cultivars was within the 10-70% range, which can be considered as a reliable rate of apex preservation in liquid nitrogen vapors in the VIR cryobank. Monitoring of the post-cryogenic regeneration of the raspberry accessions preserved in the VIR cryobank and cryopreservation of new raspberry cultivars will be continued

Hierarchical structure of pathogenic polypore fungi community on pedunculate oak in the oak forests of the southwest of the Central russian upland

The article deals with the possibilities of typological classification and hierarchical subordination of the communities of pathogenic polypore fungi Polyporaceae s. l., associated with Pedunculate oak Quercus robur L. They allow to propose a schematic-model of the hierarchical structure of the regional community of pathogenic polypore fungi on Pedunculate oak (communities of pathogenic polypore fungi on Pedunculate oak) in the oak forests of the southwest of the Central Russian uplan

КРИОГЛОБУЛИНЕМИЯ И ВИРУС ГЕПАТИТА С

The review presents recent data on cryoglobulinemiaassociated with a hepatitis C virus: prevalence, pathogenesis, clinical manifestations, laboratory diagnostics, approaches to therapy.В обзоре представлены последние данные о криоглобулинемии, ассоциированной с вирусом гепатита С: частота встречаемости, патогенез, клинические проявления, лабораторная диагностика, подходы к терапии

Simplified assessment of the regional category of rarity of macrofungi (on the example of morchella steppicola and hemileccinum impolitum in the Belgorod region of the Russian Federation)

The article is devoted to the development of a simplified scheme for assessing the regional category of rarity of macrofungi on the example of Morchella steppicola and Hemileccinum impolitum, which live in the Belgorod region of the Russian Federatio

Features of the formation of communities of microorganisms adapting to the existing conditions in different types of agrophytocenoses

The article is devoted to studying the features of the formation of communities of microorganisms, adapting to the conditions of existence in various types of agrophytocenose

ОПЫТ ПРИМЕНЕНИЯ УРСОДЕОКСИХОЛЕВОЙ КИСЛОТЫ («УРДОКСА») В КОМПЛЕКСНОЙ ТЕРАПИИ ХРОНИЧЕСКОГО ВИРУСНОГО ГЕПАТИТА

Patients with chronic virus hepatitis (32 patients, 13 with chronic hepatitis B and 19 with chronic hepatitis C) ages from 20 to 72 with elevated levels of bilirubin and active alanine aminotransferase, aspartate aminotransferase, gamma- glutamyl transpeptidase, received ursodeoxycholic acid (Urdoxa) over the course of 12 weeks. During therapy alanine aminotransferase, aspartate aminotransferase, bilirubin and gamma-glutamyl transpeptidase levels decreased. Urdoxa demonstrated good tolerance, efficacy and no visible side effects. Thus, Urdoxa could be used in treatment of chronic viral hepatitis with cytolytic and cholestatic syndromes.32 больных с диагнозом «Хронический вирусный гепатит В или С» (13 больных хроническим гепатитом В, 19 больных хроническим гепатитом С) в возрасте от 20 до 72 лет, имеющие повышение уровнябилирубина выше нормальных величин ± повышение уровня гаммаглутамилтранспептидазы (ГГТП), получали урсодеоксихолевую кислоту (препарат «Урдокса») в течение 12 недель. На фоне терапии произошло снижение трансаминаз, билирубина и ГГТП при хорошем уровне переносимости и отсутствии побочных эффектов. Таким образом, препарат «Урдокса» может быть использован в терапии хронических вирусных гепатитов с цитолитическим и холестатическим компонентом