Low frequency radio and X-ray properties of core-collapse supernovae

Radio and X-ray studies of young supernovae probe the interaction between the supernova shock waves and the surrounding medium and give clues to the nature and past of the progenitor star. Here we discuss the early emission from type Ic SN 2002ap and argue that repeated Compton boosting of optical photons by hot electrons presents the most natural explanation of the prompt X-ray emission. We describe the radio spectrum of another type Ic SN 2003dh (GRB030329) obtained with combined GMRT and VLA data. We report on the low frequency radio monitoring of SN 1995N and our objectives of distinguishing between competing models of X-ray emission from this SN and the nature of its progenitor by X-ray spectroscopy. Radio studies on SN 2001gd, SN 2001ig and SN 2002hh are mentioned.Comment: 5 pages, 4 figures. Uses svmult.cls. To appear in proceedings of IAU Colloquium 192 "Supernovae (10 years of SN 1993J)", April 2003, Valencia, Spain, eds. J. M. Marcaide and K. W. Weile

SN 2013ab : A normal type IIP supernova in NGC 5669

We present densely-sampled ultraviolet/optical photometric and low-resolution optical spectroscopic observations of the type IIP supernova 2013ab in the nearby ($\sim$24 Mpc) galaxy NGC 5669, from 2 to 190d after explosion. Continuous photometric observations, with the cadence of typically a day to one week, were acquired with the 1-2m class telescopes in the LCOGT network, ARIES telescopes in India and various other telescopes around the globe. The light curve and spectra suggest that the SN is a normal type IIP event with a plateau duration of $\sim80$ days with mid plateau absolute visual magnitude of -16.7, although with a steeper decline during the plateau (0.92 mag 100 d$^{-1}$ in $V$ band) relative to other archetypal SNe of similar brightness. The velocity profile of SN 2013ab shows striking resemblance with those of SNe 1999em and 2012aw. Following the Rabinak & Waxman (2011) prescription, the initial temperature evolution of the SN emission allows us to estimate the progenitor radius to be $\sim$ 800 R$_{\odot}$, indicating that the SN originated from a red supergiant star. The distance to the SN host galaxy is estimated to be 24.3 Mpc from expanding photosphere method (EPM). From our observations, we estimate that 0.064 M$_{\odot}$ of $^{56}$Ni was synthesized in the explosion. General relativistic, radiation hydrodynamical modeling of the SN infers an explosion energy of $0.35\times10^{51}$ erg, a progenitor mass (at the time of explosion) of $\sim9$ M$_{\odot}$ and an initial radius of $\sim600$ R$_{\odot}$.Comment: 22 pages, 18 figures, 5 tables. Accepted for publication in MNRA

Comparisons of various model fits to the Iron line profile in MCG-6-30-15

The broad Iron line in MCG-6-30-15 is fitted to the Comptonization model where line broadening occurs due to Compton down-scattering in a highly ionized optically thick cloud. These results are compared to the disk line model where the broadening is due to Gravitational/Doppler effects in the vicinity of a black hole. We find that both models fit the data well and it is not possible to differentiate between them by fitting only the ASCA data. The best fit temperature and optical depth of the cloud are found to be kT = 0.54 keV and $\tau = 4.0$ from the Comptonization model. This model further suggests that while the temperature can be assumed to be constant, the optical depth varies during the observation period. We emphasis an earlier conclusion that simultaneous broad band data ($3 - 50$ keV) can rule out (or confirm) the Comptonization model.Comment: 4 figures. uses aasms4.sty, accepted by ApJ, email: [email protected]

Globally increased ultraconserved noncoding RNA expression in pancreatic adenocarcinoma

This is the final version of the article. Available from the publisher via the DOI in this record.Transcribed ultraconserved regions (T-UCRs) are a class of non-coding RNAs with 100% sequence conservation among human, rat and mouse genomes. T-UCRs are differentially expressed in several cancers, however their expression in pancreatic adenocarcinoma (PDAC) has not been studied. We used a qPCR array to profile all 481 T-UCRs in pancreatic cancer specimens, pancreatic cancer cell lines, during experimental pancreatic desmoplasia and in the pancreases of P48Cre/wt; KrasLSL-G12D/wt mice. Fourteen, 57 and 29% of the detectable T-UCRs were differentially expressed in the cell lines, human tumors and transgenic mouse pancreases, respectively. The vast majority of the differentially expressed T-UCRs had increased expression in the cancer. T-UCRs were monitored using an in vitro model of the desmoplastic reaction. Twenty-five % of the expressed T-UCRs were increased in the HPDE cells cultured on PANC-1 cellular matrix. UC.190, UC.233 and UC.270 were increased in all three human data sets. siRNA knockdown of each of these three T-UCRs reduced the proliferation of MIA PaCa-2 cells up to 60%. The expression pattern among many T-UCRs in the human and mouse pancreases closely correlated with one another, suggesting that groups of T-UCRs are co-activated in PDAC. Successful knockout of the transcription factor EGR1 in PANC-1 cells caused a reduction in the expression of a subset of T-UCRs suggesting that EGR1 may control T-UCR expression in PDAC. We report a global increase in expression of T-UCRs in both human and mouse PDAC. Commonalties in their expression pattern suggest a similar mechanism of transcriptional upregulation for T-UCRs in PDAC.Supported by grants R21/R33CA114304 and U01CA111294. G.A.C. is supported as a Fellow at The University of Texas MD Anderson Research Trust, as a University of Texas System Regents Research Scholar and by the CLL Global Research Foundation. Work in Dr. Calin’s laboratory is supported in part by a 2009 Seena Magowitz–Pancreatic Cancer Action Network AACR Pilot Grant, the Laura and John Arnold Foundation, the RGK Foundation and the Estate of C. G. Johnson, Jr. A.C.P.A.P. was supported by NIH fellowship 5F31CA142238

A flattening in the Optical Light Curve of SN 2002ap

We present the $UBVR_cI_c$ broad band optical photometry of the Type Ic supernova SN 2002ap obtained during 2002 February 06 -- March 23 in the early decline phases and also later on 2002 15 August. Combining these data with the published ones, the general light curve development is studied. The time and luminosity of the peak brightness and the peak width are estimated. There is a flattening in the optical light curve about 30 days after the $B$ maximum. The flux decline rates before flattening are 0.127$\pm$0.005, 0.082$\pm$0.001, 0.074$\pm$0.001, 0.062$\pm$0.001 and 0.040$\pm$0.001 mag day$^{-1}$ in $U$, $B$, $V$, $R_c$ and $I_c$ passbands respectively, while the corresponding values after flattening are about 0.02 mag day$^{-1}$ in all the passbands. The maximum brightness of SN 2002ap $M_V = - 17.2$ mag, is comparable to that of the type Ic 1997ef, but fainter than that of the type Ic hypernova SN 1998bw. The peak luminosity indicates an ejection of $\sim$ 0.06 M$_{\odot}$ ${}^{56}$Ni mass. We also present low-resolution optical spectra obtained during the early phases. The SiII absorption minimum indicates that the photospheric velocity decreased from $\sim$ 21,360 km s$^{-1}$ to $\sim$ 10,740 km s$^{-1}$ during a period of $\sim$ 6 days.Comment: 7 pages, 5 figures, Submitted to MNRA

Massive stars as thermonuclear reactors and their explosions following core collapse

Nuclear reactions transform atomic nuclei inside stars. This is the process of stellar nucleosynthesis. The basic concepts of determining nuclear reaction rates inside stars are reviewed. How stars manage to burn their fuel so slowly most of the time are also considered. Stellar thermonuclear reactions involving protons in hydrostatic burning are discussed first. Then I discuss triple alpha reactions in the helium burning stage. Carbon and oxygen survive in red giant stars because of the nuclear structure of oxygen and neon. Further nuclear burning of carbon, neon, oxygen and silicon in quiescent conditions are discussed next. In the subsequent core-collapse phase, neutronization due to electron capture from the top of the Fermi sea in a degenerate core takes place. The expected signal of neutrinos from a nearby supernova is calculated. The supernova often explodes inside a dense circumstellar medium, which is established due to the progenitor star losing its outermost envelope in a stellar wind or mass transfer in a binary system. The nature of the circumstellar medium and the ejecta of the supernova and their dynamics are revealed by observations in the optical, IR, radio, and X-ray bands, and I discuss some of these observations and their interpretations.Comment: To be published in " Principles and Perspectives in Cosmochemistry" Lecture Notes on Kodai School on Synthesis of Elements in Stars; ed. by Aruna Goswami & Eswar Reddy, Springer Verlag, 2009. Contains 21 figure

Gamow-Teller strength distributions for nuclei in pre-supernova stellar cores

Electron-capture and $\beta$-decay of nuclei in the core of massive stars play an important role in the stages leading to a type II supernova explosion. Nuclei in the f-p shell are particularly important for these reactions in the post Silicon-burning stage of a presupernova star. In this paper, we characterise the energy distribution of the Gamow-Teller Giant Resonance (GTGR) for mid-fp-shell nuclei in terms of a few shape parameters, using data obtained from high energy, forward scattering (p,n) and (n,p) reactions. The energy of the GTGR centroid $E_{GT}$ is further generalised as function of nuclear properties like mass number, isospin and other shell model properties of the nucleus. Since a large fraction of the GT strength lies in the GTGR region, and the GTGR is accessible for weak transitions taking place at energies relevant to the cores of presupernova and collapsing stars, our results are relevant to the study of important $e^-$-capture and $\beta$-decay rates of arbitrary, neutron-rich, f-p shell nuclei in stellar cores. Using the observed GTGR and Isobaric Analog States (IAS) energy systematics we compare the coupling coefficients in the Bohr-Mottelson two particle interaction Hamiltonian for different regions of the Isotope Table.Comment: Revtex, 28 pages +7 figures (PostScript Figures, uuencoded, filename: Sutfigs.uu). If you have difficulty printing the figures, please contact [email protected]. Accepted for publication in Phys. Rev. C, Nov 01, 199

Oestrogen increases S-phase fraction and oestrogen and progesterone receptors in human cervical cancer in vivo.

Although cancer of the cervix is traditionally considered not to be responsive to steroid hormones, an in vitro study has reported that the addition of oestrogen increased cellular proliferation in a cervix cancer cell line that was inhibited by progesterone. We investigated whether the reported in vitro effects of oestrogen and progesterone on cellular proliferation can be replicated in locally advanced cervical cancer in vivo and whether these effects, if any, are related to oestrogen and progesterone receptor (ER and PgR) content of the tumour. One hundred post-menopausal patients with locally advanced cervical cancer were systematically allocated by rotation to the four treatment groups: (1) control group receiving no treatment; (2) ethinyl oestradiol 50 micrograms: (3) norethisterone 5 mg: (4) a combination of ethinyl oestradiol and norethisterone. Hormone treatment (five doses) was given orally every 12 h. Tissue biopsies were taken before and 12 h after the last hormone treatment. S-phase fraction (SpF) was measured by flow cytometry, and ER and PgR were measured by enzyme immunoassay. Results were analysed using two-factor analysis of variance, the factors being oestrogen-absent or present- and progesterone-absent or present. The main effects of oestrogen were increases in SpF, ER and PgR, which were statistically significant (P = 0.0056, 0.0009 and 0.01 respectively), indicating that there is much greater change in these three parameters in the presence of oestrogen (mean changes 7.808%, 6.258 fmol mg-1 and 12.716 fmol mg-1 for SpF, ER and PgR respectively) than in its absence (mean change -1.986%,-3.041 fmol mg-1 and 1.736 fmol mg-1 respectively). The progestogen main effect and the oestrogen-progestogen interaction were not significant. The rise in SpF, ER and PgR in the presence of oestrogen had a correlation coefficient with the initial ER values of -0.0565, -0.2863 and -0.1230 respectively, none being statistically significant, suggesting that the oestrogen actions were not strictly related to baseline ER concentrations. The combined median baseline ER and PgR values of the four groups were 1.48 fmol mg-1 and 0.80 fmol mg-1 respectively. Our results show that oestrogen is capable of increasing SpF in locally advanced cervical cancer in vivo and may help to revive interest in the use of oestrogen as a radiosensitizing agent in the treatment of this disease

A deeper search for the progenitor of the Type Ic Supernova 2002ap

(Abridged) We present a search for the progenitor star of the Type Ic Supernova 2002ap in deep, high quality pre-explosion observations taken with the Canada-France-Hawaii Telescope (CFHT). Aligning high-resolution Hubble Space Telescope (HST) observations of the supernova itself with the archival CFHT images allowed us to pinpoint the location of the progenitor site on the ground based observations. We find that a source visible in the B and R band pre-explosion images close to the position of the SN is (1) not coincident with the SN position within the uncertainties of our relative astrometry, and (2) is still visible ~ 4.7 yrs post-explosion in late-time observations taken with the William Herschel Telescope. We therefore conclude that it is not the progenitor of SN 2002ap. Comparing our luminosity limits with stellar models of single stars at appropriate metallicity (Z=0.008) we conclude that any single star progenitor must have experienced at least twice the standard mass loss rates during pre-Wolf-Rayet evolution, been initially > 30-40M(Sun) and exploded as a Wolf-Rayet star of final mass 10-12M(Sun). Alternatively an initially less massive progenitor may have evolved in an interacting binary system. We constrain any possible binary companion to a main sequence star of < 20M(Sun), a neutron star or a black hole. By combining the pre-explosion limits with the ejecta mass estimates and constraints from X-ray and radio observations we conclude that any binary interaction most likely occurred as Case B mass transfer, either with or without a subsequent common envelope evolution phase.Comment: 20 pages, 11 figures (resolution of images reduced), 6 tables. Accepted for publication in MNRAS 2007 July 27 (received 2007 July 23; in original form 2007 June 04

High-energy spectral and temporal characteristics of GRO J1008-57

A transient X-ray source, GRO J1008-57, was discovered by the Burst and Transient Source Experiment (BATSE) on board the Compton Gamma Ray Observatory (CGRO) in 1993 July. It reached a maximum intensity of about 1.4 times that of the Crab, in the 20-60 keV energy band. Pulsations in the X-ray intensity were detected at a period of 93.5 s. It has subsequently been determined to be a member of the Be star subclass of X-ray transients. In addition to BATSE, GRO J1008-57 was observed during its outburst by several pointed high-energy experiments: ROSAT, ASCA, and CGRO/OSSE. These nonsimultaneous but contemporaneous observations took place near and shortly after the peak of the outburst light curve. We report for the first time on a combined analysis of the CGRO and ASCA data sets. We have attempted to model the broadband high-energy continuum distribution and phase-resolved spectra. The broadband, phase-averaged continuum is well approximated by a power law with an exponential cutoff. Evidence for 6.4 keV line emission due to Fe is presented based on our spectral analysis. The energy dependence of the pulse profiles is examined in order to determine the energy at which the low-energy double-peaked profile detected by ASCA evolves into single-peaked pulse profile detected by BATSE. We discuss the implications of this pulse profile for the magnetic field and beam distribution for GRO J1008-57. Analysis of the BATSE and Rossi X-Ray Timing Explorer/ASM flux histories suggests that Porbital~135 days. We further suggest that a transient disk is likely to form during episodes of outbursts