38,053 research outputs found
Gravitational vacuum polarization III: Energy conditions in the (1+1) Schwarzschild spacetime
Building on a pair of earlier papers, I investigate the various point-wise
and averaged energy conditions for the quantum stress-energy tensor
corresponding to a conformally-coupled massless scalar field in the in the
(1+1)-dimensional Schwarzschild spacetime. Because the stress-energy tensors
are analytically known, I can get exact results for the Hartle--Hawking,
Boulware, and Unruh vacua. This exactly solvable model serves as a useful
sanity check on my (3+1)-dimensional investigations wherein I had to resort to
a mixture of analytic approximations and numerical techniques. Key results in
(1+1) dimensions are: (1) NEC is satisfied outside the event horizon for the
Hartle--Hawking vacuum, and violated for the Boulware and Unruh vacua. (2) DEC
is violated everywhere in the spacetime (for any quantum state, not just the
standard vacuum states).Comment: 7 pages, ReV_Te
Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR)
<p><b>Background and Purpose:</b> The optimal management of blood pressure (BP) in acute stroke remains unclear. For ischemic stroke treated with intravenous thrombolysis, current guidelines suggest pharmacological intervention if systolic BP exceeds 180 mm Hg. We determined retrospectively the association of BP and antihypertensive therapy with clinical outcomes after stroke thrombolysis.</p>
<p><b>Methods:</b> The SITS thrombolysis register prospectively recorded 11 080 treatments from 2002 to 2006. BP values were recorded at baseline, 2 hours, and 24 hours after thrombolysis. Outcomes were symptomatic (National Institutes of Health Stroke Scale score deterioration ≥4) intracerebral hemorrhage Type 2, mortality, and independence at (modified Rankin Score 0 to 2) 3 months. Patients were categorized by history of hypertension and antihypertensive therapy within 7 days after thrombolysis: Group 1, hypertensive treated with antihypertensives (n=5612); Group 2, hypertensive withholding antihypertensives (n=1573); Group 3, without history of hypertension treated with antihypertensives (n=995); and Group 4, without history of hypertension not treated with antihypertensives (n=2632). For 268 (2.4%) patients, these data were missing. Average systolic BP 2 to 24 hours after thrombolysis was categorized by 10-mm Hg intervals with 100 to 140 used as a reference.</p>
<p><b>Results:</b> In multivariable analysis, high systolic BP 2 to 24 hours after thrombolysis as a continuous variable was associated with worse outcome (P<0.001) and as a categorical variable had a linear association with symptomatic hemorrhage and a U-shaped association with mortality and independence with systolic BP 141 to 150 mm Hg associated with most favorable outcomes. OR (95% CI) from multivariable analysis showed no difference in symptomatic hemorrhage (1.09 [0.83 to 1.51]; P=0.58) and independence (1.03 [0.93 to 1.10]; P=0.80) but lower mortality (0.82 [0.73 to 0.92]; P=0.0007) for Group 1 compared with Group 4. Group 2 had a higher symptomatic hemorrhage (1.86 [1.34 to 2.68]; P=0.0004) and mortality (1.62 [1.41 to 1.85]; P<0.0001) and lower independence (0.89 [0.80 to 0.99]; P=0.04) compared with Group 4. Group 3 had similar results as Group 1.</p>
<p><b>Conclusions:</b> There is a strong association of high systolic BP after thrombolysis with poor outcome. Withholding antihypertensive therapy up to 7 days in patients with a history of hypertension was associated with worse outcome, whereas initiation of antihypertensive therapy in newly recognized moderate hypertension was associated with a favorable outcome.</p>
Scalar Field Quantum Inequalities in Static Spacetimes
We discuss quantum inequalities for minimally coupled scalar fields in static
spacetimes. These are inequalities which place limits on the magnitude and
duration of negative energy densities. We derive a general expression for the
quantum inequality for a static observer in terms of a Euclidean two-point
function. In a short sampling time limit, the quantum inequality can be written
as the flat space form plus subdominant correction terms dependent upon the
geometric properties of the spacetime. This supports the use of flat space
quantum inequalities to constrain negative energy effects in curved spacetime.
Using the exact Euclidean two-point function method, we develop the quantum
inequalities for perfectly reflecting planar mirrors in flat spacetime. We then
look at the quantum inequalities in static de~Sitter spacetime, Rindler
spacetime and two- and four-dimensional black holes. In the case of a
four-dimensional Schwarzschild black hole, explicit forms of the inequality are
found for static observers near the horizon and at large distances. It is show
that there is a quantum averaged weak energy condition (QAWEC), which states
that the energy density averaged over the entire worldline of a static observer
is bounded below by the vacuum energy of the spacetime. In particular, for an
observer at a fixed radial distance away from a black hole, the QAWEC says that
the averaged energy density can never be less than the Boulware vacuum energy
density.Comment: 27 pages, 2 Encapsulated Postscript figures, uses epsf.tex, typeset
in RevTe
A New Generation Gap? Some thoughts on the consequences of increasingly early ICT first contact
One possible consequence of ICT’s rapid rise will be a new ‘generation gap’ arising from differing perceptions of the learning technologies. The nature, causes and consequences of this gap are of interest to educational practitioners and policymakers.
This paper uses data from an ongoing project together with a synopsis of research to describe the ICT-based generation gap that currently exists between students and their teachers and parents. It is argued that this gap may exist between students differing in age by as little as five years.
Results from a related project exploring Networked Information and Communication Literacy Skills (NICLS), are used to introduce a discussion on the nature of any skills gap that must be addressed in the light of this generation gap
A quantum violation of the second law?
An apparent violation of the second law of thermodynamics occurs when an atom
coupled to a zero-temperature bath, being necessarily in an excited state, is
used to extract work from the bath. Here the fallacy is that it takes work to
couple the atom to the bath and this work must exceed that obtained from the
atom. For the example of an oscillator coupled to a bath described by the
single relaxation time model, the mean oscillator energy and the minimum work
required to couple the oscillator to the bath are both calculated explicitly
and in closed form. It is shown that the minimum work always exceeds the mean
oscillator energy, so there is no violation of the second law
Gravitons and Lightcone Fluctuations II: Correlation Functions
A model of a fluctuating lightcone due to a bath of gravitons is further
investigated. The flight times of photons between a source and a detector may
be either longer or shorter than the light propagation time in the background
classical spacetime, and will form a Gaussian distribution centered around the
classical flight time. However, a pair of photons emitted in rapid succession
will tend to have correlated flight times. We derive and discuss a correlation
function which describes this effect. This enables us to understand more fully
the operational significance of a fluctuating lightcone. Our results may be
combined with observational data on pulsar timing to place some constraints on
the quantum state of cosmological gravitons.Comment: 16 pages and two figures, uses eps
A `warp drive' with more reasonable total energy requirements
I show how a minor modification of the Alcubierre geometry can dramatically
improve the total energy requirements for a `warp bubble' that can be used to
transport macroscopic objects. A spacetime is presented for which the total
negative mass needed is of the order of a few solar masses, accompanied by a
comparable amount of positive energy. This puts the warp drive in the mass
scale of large traversable wormholes. The new geometry satisfies the quantum
inequality concerning WEC violations and has the same advantages as the
original Alcubierre spacetime.Comment: 9 pages, 1 figure; error in calculation correcte
Quantum Inequalities on the Energy Density in Static Robertson-Walker Spacetimes
Quantum inequality restrictions on the stress-energy tensor for negative
energy are developed for three and four-dimensional static spacetimes. We
derive a general inequality in terms of a sum of mode functions which
constrains the magnitude and duration of negative energy seen by an observer at
rest in a static spacetime. This inequality is evaluated explicitly for a
minimally coupled scalar field in three and four-dimensional static
Robertson-Walker universes. In the limit of vanishing curvature, the flat
spacetime inequalities are recovered. More generally, these inequalities
contain the effects of spacetime curvature. In the limit of short sampling
times, they take the flat space form plus subdominant curvature-dependent
corrections.Comment: 18 pages, plain LATEX, with 3 figures, uses eps
The Health of Aging Lesbian, Gay and Bisexual Adults in California
Examines rates of diabetes, hypertension, poor mental health, physical disability, and fair or poor self-reported health status among homosexual adults ages 50 to 70 compared with their heterosexual peers. Recommends enhancing policies and practices
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