230 research outputs found
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Current trends in the packaging of photonic devices
Optoelectronic and photonic devices hold great promise for high data-rate communication and computing. Their wide implementation was limited first by the device technologies and now suffers due to the need for high-precision packaging that is mass-produced. The use of photons as a medium of communication and control implies a unique set of packaging constraints that are highly driven by the need for micron and even sub-micron alignments between photonic devices and their transmission media. Current trends in optoelectronic device packaging are reviewed and future directions are identified both for free-space (3-dimensional) and guided-wave (2-dimensional) photonics. Emphasis will be placed on the special needs generated by increasing levels of device integration
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Smart packaging for photonics
Unlike silicon microelectronics, photonics packaging has proven to be low yield and expensive. One approach to make photonics packaging practical for low cost applications is the use of {open_quotes}smart{close_quotes} packages. {open_quotes}Smart{close_quotes} in this context means the ability of the package to actuate a mechanical change based on either a measurement taken by the package itself or by an input signal based on an external measurement. One avenue of smart photonics packaging, the use of polysilicon micromechanical devices integrated with photonic waveguides, was investigated in this research (LDRD 3505.340). The integration of optical components with polysilicon surface micromechanical actuation mechanisms shows significant promise for signal switching, fiber alignment, and optical sensing applications. The optical and stress properties of the oxides and nitrides considered for optical waveguides and how they are integrated with micromechanical devices were investigated
Differential metabolism of deoxyribonucleosides by leukaemic T cells of immature and mature phenotype
Experimental evidence has indicated that T lymphoblasts are more sensitive to deoxynucleoside toxicity than are B lymphoblasts. These data have led to the use of purine enzyme inhibitors as selective chemotherapeutic drugs in the treatment of T cell malignancies ranging from T cell acute lymphoblastic leukaemia to cutaneous T cell lymphomas. We have compared the toxicities of 2âČ-deoxyadenosine, 2âČ-deoxyguanosine, and thymidine for T cell lines derived from patients with T cell acute lymphoblastic leukaemia with those for mature T cell lines derived from patients with cutaneous T cell leukaemia/lymphoma. We have found that both deoxynucleosides are far less toxic to the mature T cell lies than to T lymphoblasts and that the mature cells accumulate much lower amounts of dATP and dGTP when exposed to deoxyadenosine and deoxyguanosine, respectively. Similar studies performed on peripheral blood cells from patients with T cell leukaemias of mature phenotype and on peripheral blood T cells demonstrate similar low amounts of deoxynucleotide accumulation. Measurements of the activities of several purine metabolizing enzymes that participate in deoxynucleoside phosphorylation or degradation do not reveal differences which would explain the toxicity of deoxynucleosides for immature, as compared to mature, T cells. We conclude that deoxynucleoside metabolism in leukaemic T cells varies with their degree of differentiation. These observations may be relevant to the design of chemotherapeutic regimes for T cell malignancies.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72479/1/j.1365-2141.1985.tb04067.x.pd
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An entomocentric view of the Janzen-Connell hypothesis
In 1987, in the first issue of Conservation Biology, Edward O. Wilson wrote about the âlittle things that run the worldâ â the importance and conservation of insects (Wilson, 1987). Readers of Insect Conservation and Diversity will no doubt be very familiar with the concept. Sadly, however, this perception is not as widely shared among the rest of the scientific community as it should be, and insects are still comparatively neglected as a prime focus of scientific investigations
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Low-power multi-chip module and board-level links for data transfer
Advanced device technologies such as Vertical Cavity Surface-Emitting Lasers (VCSELs) and diffractive micro lenses can be obtained with novel packaging techniques to allow low-power interconnection of parallel optical signals. These interconnections can be realized directly on circuit boards, in a multi-chip module format, or in packages that emulate electrical connectors. For applications such as stacking of Multi-Chip Module (MCM) layers, the links may be realized in bi-directional form using integrated diffractive microlenses. In the stacked MCM design, consumed electrical power is minimized by use of a relatively high laser output from high efficiency VCSELs, and a receiver design that is optimized for low power, at the expense of dynamic range. Within certain constraints, the design may be extended to other forms such as board-level interconnects
A Way to Reopen the Window for Electroweak Baryogenesis
We reanalyse the sphaleron bound of electroweak baryogenesis when allowing
deviations to the Friedmann equation. These modifications are well motivated in
the context of brane cosmology where they appear without being in conflict with
major experimental constraints on four-dimensional gravity. While suppressed at
the time of nucleosynthesis, these corrections can dominate at the time of the
electroweak phase transition and in certain cases provide the amount of
expansion needed to freeze out the baryon asymmetry without requiring a
strongly first order phase transition. The sphaleron bound is substantially
weakened and can even disappear so that the constraints on the higgs and stop
masses do not apply anymore. Such modification of cosmology at early times
therefore reopens the parameter space allowing electroweak baryogenesis which
had been reduced substantially given the new bound on the higgs mass imposed by
LEP. In contrast with previous attempts to turn around the sphaleron bound
using alternative cosmologies, we are still considering that the electroweak
phase transition takes place in a radiation dominated universe. The universe is
expanding fast because of the modification of the Friedmann equation itself
without the need for a scalar field and therefore evading the problem of the
decay of this scalar field after the completion of the phase transition and the
risk that its release of entropy dilutes the baryon asymmetry produced at the
transition.Comment: 19 pages, 3 figures; v2: minor changes, remark added at end of
section 5 and in caption of figure 1; v3: references added, version to be
publishe
One-loop corrections to the metastable vacuum decay
We evaluate the one-loop prefactor in the false vacuum decay rate in a theory
of a self interacting scalar field in 3+1 dimensions. We use a numerical
method, established some time ago, which is based on a well-known theorem on
functional determinants. The proper handling of zero modes and of
renormalization is discussed. The numerical results in particular show that
quantum corrections become smaller away from the thin-wall case. In the
thin-wall limit the numerical results are found to join into those obtained by
a gradient expansion.Comment: 31 pages, 7 figure
Measurement of the branching fraction
The branching fraction is measured in a data sample
corresponding to 0.41 of integrated luminosity collected with the LHCb
detector at the LHC. This channel is sensitive to the penguin contributions
affecting the sin2 measurement from The
time-integrated branching fraction is measured to be . This is the most precise measurement to
date
Model-independent search for CP violation in D0âKâK+ÏâÏ+ and D0âÏâÏ+Ï+Ïâ decays
A search for CP violation in the phase-space structures of D0 and View the MathML source decays to the final states KâK+ÏâÏ+ and ÏâÏ+Ï+Ïâ is presented. The search is carried out with a data set corresponding to an integrated luminosity of 1.0 fbâ1 collected in 2011 by the LHCb experiment in pp collisions at a centre-of-mass energy of 7 TeV. For the KâK+ÏâÏ+ final state, the four-body phase space is divided into 32 bins, each bin with approximately 1800 decays. The p-value under the hypothesis of no CP violation is 9.1%, and in no bin is a CP asymmetry greater than 6.5% observed. The phase space of the ÏâÏ+Ï+Ïâ final state is partitioned into 128 bins, each bin with approximately 2500 decays. The p-value under the hypothesis of no CP violation is 41%, and in no bin is a CP asymmetry greater than 5.5% observed. All results are consistent with the hypothesis of no CP violation at the current sensitivity
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