Research Article

Mixed modeling and sample size calculations for identifying housekeeping gene

Spinning up a Daze: TESS Uncovers a Hot Jupiter orbiting the Rapid-Rotator TOI-778

NASA's Transiting Exoplanet Survey Satellite (TESS) mission, has been uncovering a growing number of exoplanets orbiting nearby, bright stars. Most exoplanets that have been discovered by TESS orbit narrow-line, slow-rotating stars, facilitating the confirmation and mass determination of these worlds. We present the discovery of a hot Jupiter orbiting a rapidly rotating (vsin(i)=35.1±1.0km/s) early F3V-dwarf, HD115447 (TOI-778). The transit signal taken from Sectors 10 and 37 of TESS's initial detection of the exoplanet is combined with follow-up ground-based photometry and velocity measurements taken from Minerva-Australis, TRES, CORALIE and CHIRON to confirm and characterise TOI-778b. A joint analysis of the light curves and the radial velocity measurements yield a mass, radius, and orbital period for TOI-778b of 2.76+0.24−0.23Mjup, 1.370±0.043Rjup and ∼4.63 days, respectively. The planet orbits a bright (V=9.1mag) F3-dwarf with M=1.40±0.05Msun, R=1.70±0.05Rsun, and logg=4.05±0.17. We observed a spectroscopic transit of TOI-778b, which allowed us to derive a sky-projected spin-orbit angle of 18∘±11∘, consistent with an aligned planetary system. This discovery demonstrates the capability of smaller aperture telescopes such as Minerva-Australis to detect the radial velocity signals produced by planets orbiting broad-line, rapidly rotating stars

Mild Concussion, but Not Moderate Traumatic Brain Injury, Is Associated with Long-Term Depression-Like Phenotype in Mice

Mild traumatic brain injuries can lead to long-lasting cognitive and motor deficits, increasing the risk of future behavioral, neurological, and affective disorders. Our study focused on long-term behavioral deficits after repeated injury in which mice received either a single mild CHI (mCHI), a repeated mild CHI (rmCHI) consisting of one impact to each hemisphere separated by 3 days, or a moderate controlled cortical impact injury (CCI). Shams received only anesthesia. Behavioral tests were administered at 1, 3, 5, 7, and 90 days post-injury (dpi). CCI animals showed significant motor and sensory deficits in the early (1-7 dpi) and long-term (90 dpi) stages of testing. Interestingly, sensory and subtle motor deficits in rmCHI animals were found at 90 dpi. Most importantly, depression-like behaviors and social passiveness were observed in rmCHI animals at 90 dpi. These data suggest that mild concussive injuries lead to motor and sensory deficits and affective disorders that are not observed after moderate TBI