8 research outputs found
Novel antiangiogenic peptide agents and their therapeutic and diagnostic use
Full text linkpublication date: 2008-04-17; filing date: 2007-10-19The current invention concerns novel antiangiogenic peptides which correspond to about 10 to about 150 consecutive amino acids of N-terminal sequences of human growth hormones, human placental lactogen, human growth hormone variant hGH-V, and prolactin, and their use in inhibiting angiogenesis and in the diagnosis of diseases of human pregnancy involving abnormalities of placental vascularization
Antagonistic regulation by intact and N-terminal fragment of the human Prolactin/Growth Hormone family members : a novel mechanism for regulation of angiogenesis
Full text linkThe 16 kDa fragments of the PRL/GH family inhibit angiogenesis whereas the full-length hormones stimulate blood vessel formation
Full text linkEfficacy, safety, pharmacokinetics and pharmacodynamics of SAR245409 (voxtalisib, XL765), an orally administered phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor: a phase 1 expansion cohort in patients with relapsed or refractory lymphoma
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