Brain metastases from breast cancer:Management approach

Brain metastases are a significant cause of morbidity and mortality in patients with breast cancer. HER-2 positivity is an increasingly recognized risk factor for the development of brain metastases. Although considerable progress has been made in the treatment of this complication, supportive measures like steroids, anti-seizure medication and whole-brain radiation remain the cornerstones of management in the majority of patients. The current review discusses the above and other issues like surgical excision, stereotactic radiotherapy, adjuvant radiation, radiosensitization and chemotherapy. A brief discussion of the recent evidence for the use of \u2032HER-1/ HER-2\u2032-targeted therapy is also present

Brain metastases from breast cancer:Management approach

Brain metastases are a significant cause of morbidity and mortality in patients with breast cancer. HER-2 positivity is an increasingly recognized risk factor for the development of brain metastases. Although considerable progress has been made in the treatment of this complication, supportive measures like steroids, anti-seizure medication and whole-brain radiation remain the cornerstones of management in the majority of patients. The current review discusses the above and other issues like surgical excision, stereotactic radiotherapy, adjuvant radiation, radiosensitization and chemotherapy. A brief discussion of the recent evidence for the use of ′HER-1/ HER-2′-targeted therapy is also present

Brain metastases from breast cancer:Management approach

Brain metastases are a significant cause of morbidity and mortality in patients with breast cancer. HER-2 positivity is an increasingly recognized risk factor for the development of brain metastases. Although considerable progress has been made in the treatment of this complication, supportive measures like steroids, anti-seizure medication and whole-brain radiation remain the cornerstones of management in the majority of patients. The current review discusses the above and other issues like surgical excision, stereotactic radiotherapy, adjuvant radiation, radiosensitization and chemotherapy. A brief discussion of the recent evidence for the use of ′HER-1/ HER-2′-targeted therapy is also present

LANGUAGE IN INDIA Strength for Today and Bright Hope for Tomorrow Questioning the Motherhood in Mother: Dalit Identity against the Emotions of a Dalit Woman

Abstract The Constitution and laws in India prohibit untouchability. But Dalits still have no better alternative than to perform the traditional occupations, considered to be menial and lowly, in many places. Migration and the obscurity of urban environment have in som