Triggered massive-star formation on the borders of Galactic HII regions. III. Star formation at the periphery of Sh2-219

Context. Massive-star formation triggered by the expansion of HII regions. Aims. To understand if sequential star formation is taking place at the periphery of the HII region Sh2-219. Methods. We present 12CO(2-1) line observations of this region, obtained at the IRAM 30-m telescope (Pico Veleta, Spain). Results. In the optical, Sh2-219 is spherically symmetric around its exciting star; furthermore it is surrounded along three quarters of its periphery by a ring of atomic hydrogen. This spherical symmetry breaks down at infrared and millimetre wavelengths. A molecular cloud of about 2000\msol lies at the southwestern border of Sh2-219, in the HI gap. Two molecular condensations, elongated along the ionization front, probably result from the interaction between the expanding HII region and the molecular cloud. In this region of interaction there lies a cluster containing many highly reddened stars, as well as a massive star exciting an ultracompact HII region. More surprisingly, the brightest parts of the molecular cloud form a `chimney', perpendicular to the ionization front. This chimney is closed at its south-west extremity by H-alpha walls, thus forming a cavity. The whole structure is 7.5 pc long. A luminous H-alpha emission-line star, lying at one end of the chimney near the ionization front, may be responsible for this structure. Confrontation of the observations with models of HII region evolution shows that Sh2-219 is probably 10^5 yr old. The age and origin of the near-IR cluster observed on the border of Sh2-219 remain unknown.Comment: 11 pages, 10 figures. To be published in A&

The 3Rs of Cell Therapy

The 3Rs for a good education are “reading, 'riting, and 'rithmetic.” The basis for good health care solutions for the emergent field of cell therapy in the future will also involve 3Rs: regulation, reimbursement, and realization of value. The business models in this new field of cell therapy will involve these 3Rs. This article brings forth realities facing this new industry for its approaches to provide curative health care solutions

High reward makes items easier to remember, but harder to bind to a new temporal context

Learning through reward is central to adaptive behavior. Indeed, items are remembered better if they are experienced while participants expect a reward, and people can deliberately prioritize memory for high- over low-valued items. Do memory advantages for high-valued items only emerge after deliberate prioritization in encoding? Or, do reward-based memory enhancements also apply to unrewarded memory tests and to implicit memory? First, we tested for a high-value memory advantage in unrewarded implicit- and explicit-tests (Experiment 1). Participants first learned high or low-reward values of 36 words, followed by unrewarded lexical decision and free-recall tests. High-value words were judged faster in lexical decision, and more often recalled in free recall. These two memory advantages for high-value words were negatively correlated suggesting at least two mechanisms by which reward value can influence later item-memorability. The ease with which the values were originally acquired explained the negative correlation: people who learned values earlier showed reward effects in implicit memory whereas people who learned values later showed reward effects in explicit memory. We then asked whether a high-value advantage would persist if trained items were linked to a new context (Experiments 2a and 2b). Following the same value training as in Experiment 1, participants learned lists composed of previously trained words mixed with new words, each followed by free recall. Thus, participants had to retrieve words only from the most recent list, irrespective of their values. High- and low-value words were recalled equally, but low-value words were recalled earlier than high-value words and high-value words were more often intruded (proactive interference). Thus, the high-value advantage holds for implicit- and explicit-memory, but comes with a side effect: High-value items are more difficult to relearn in a new context. Similar to emotional arousal, reward value can both enhance and impair memory

Emotional arousal impairs association-memory: roles of amygdala and hippocampus

Emotional arousal is well-known to enhance memory for individual items or events, whereas it can impair association memory. The neural mechanism of this association memory impairment by emotion is not known: In response to emotionally arousing information, amygdala activity may interfere with hippocampal associative encoding (e.g., via prefrontal cortex). Alternatively, emotional information may be harder to unitize, resulting in reduced availability of extra-hippocampal medial temporal lobe support for emotional than neutral associations. To test these opposing hypotheses, we compared neural processes underlying successful and unsuccessful encoding of emotional and neutral associations. Participants intentionally studied pairs of neutral and negative pictures (Experiments 1–3). We found reduced association-memory for negative pictures in all experiments, accompanied by item-memory increases in Experiment 2. High-resolution fMRI (Experiment 3) indicated that reductions in associative encoding of emotional information are localizable to an area in ventral-lateral amygdala, driven by attentional/salience effects in the central amygdala. Hippocampal activity was similar during both pair types, but a left hippocampal cluster related to successful encoding was observed only for negative pairs. Extra-hippocampal associative memory processes (e.g., unitization) were more effective for neutral than emotional materials. Our findings suggest that reduced emotional association memory is accompanied by increases in activity and functional coupling within the amygdala. This did not disrupt hippocampal association-memory processes, which indeed were critical for successful emotional association memory formation

Diffuse Ionized Gas in the Dwarf Irregular Galaxy DDO 53

The spectral characteristics throughout the dwarf irregular galaxy DDO 53 are studied. The results are very similar to those for other irregular galaxies: high excitation and low values of the [SII]/Halpha ratio. The most likely ionization source is photon leakage from the classical HII regions, without any other source, although the interstellar medium of the galaxy is quite perturbed. Moreover, the physical conditions throughout the galaxy do not change very much because both the photon leakage percentage and the ionization temperature are very similar. In addition, the determined metal content for two HII regions indicates that DDO 53 is a low-metallicity galaxy.Comment: 32 pages, 9 figures, 7 tables. AJ, in pres

Optical Spectral Signatures of Dusty Starburst Galaxies

We analyse the optical spectral properties of the complete sample of Very Luminous Infrared Galaxies presented by Wu et al. (1998a,b) and we find a high fraction (~50 %) of spectra showing both a strong H_delta line in absorption and relatively modest [OII] emission (e(a) spectra). The e(a) signature has been proposed as an efficient method to identify dusty starburst galaxies and we study the star formation activity and the nature of these galaxies, as well as the effects of dust on their observed properties. We examine their emission line characteristics, in particular their [OII]/H_alpha ratio, and we find this to be greatly affected by reddening. A search for AGN spectral signatures reveals that the e(a)'s are typically HII/LINER galaxies. We compare the star formation rates derived from the FIR luminosities with the estimates based on the H_alpha line and find that the values obtained from the optical emission lines are a factor of 10-70 (H_alpha) and 20-140 ([OII]) lower than the FIR estimates (50-300 M_sun yr^-1). We then study the morphological properties of the e(a) galaxies, looking for a near companion or signs of a merger/interaction. In order to explore the evolution of the e(a) population, we present an overview of the available observations of e(a)'s in different environments both at low and high redshift. Finally, we discuss the role of dust in determining the e(a) spectral properties and we propose a scenario of selective obscuration in which the extinction decreases with the stellar age.Comment: 26 pages, Latex, including 7 postscript figures, accepted for publication in the Astrophysical Journa

The Radio Continuum of the Metal-Deficient Blue Compact Dwarf Galaxy SBS0335-052

We present new Very Large Array observations at five frequencies, from 1.4 to 22GHz, of the extremely low-metallicity blue compact dwarf SBS0335-052. The radio spectrum shows considerable absorption at 1.49GHz, and a composite thermal+non-thermal slope. After fitting the data with a variety of models, we find the best-fitting geometry to be one with free-free absorption homogeneously intermixed with the emission of both thermal and non-thermal components. The best-fitting model gives an an emission measure EM ~ 8x10^7pc cm^{-6} and a diameter of the radio-emitting region D ~17pc. The inferred density is n_e ~ 2000 cm^{-3}. The thermal emission comes from an ensemble of \~9000 O7 stars, with a massive star-formation rate (>=5Msun) of 0.13-0.15 yr^{-1}, and a supernova rate of 0.006 yr^{-1}. We find evidence for ionized gas emission from stellar winds, since the observed Bralpha line flux significantly exceeds that inferred from the thermal radio emission. The non-thermal fraction at 5GHz is ~0.7, corresponding to a non-thermal luminosity of ~2x10^{20} W Hz^{-1}. We attribute the non-thermal radio emission to an ensemble of compact SN remnants expanding in a dense interstellar medium, and derive an equipartition magnetic field of ~0.6-1 mG, and a pressure of \~3x10^{-8}-1x10^{-7} dyne cm^{-2}. If the radio properties of SBS0335-052 are representative of star formation in extremely low-metallicity environments, derivations of the star formation rate from the radio continuum in high redshift primordial galaxies need to be reconsidered. Moreover, photometric redshifts inferred from ``standard'' spectral energy distributions could be incorrect.Comment: 25 pages, including 3 figures, accepted for publication in Ap

ROSAT and ASCA observations of the Crab-Like Supernova Remnant N157B in the Large Magellanic Cloud

We report the results of ROSAT and ASCA X-ray observations of the supernova remnant N157B (or 30 Dor B, SNR 0539-69.1) in the Large Magellanic Cloud. For comparison, we also briefly describe the results on SNR 0540-69.3, the only confirmed Crab-like remnant in the Cloud. The X-ray emission from N157B can be decomposed into a bright comet-shaped feature, superimposed on a diffuse emission region of a dimension $\sim 20$ pc. The flat and nearly featureless spectrum of the remnant is distinctly different from those of young shell-like remnants, suggesting a predominantly Crab-like nature of N157B. Characterized by a power law with an energy slope $\sim 1.5$, the spectrum of N157B above $\sim 2$ keV is, however, considerably steeper than that of SNR 0540-69.3, which has a slope of $\sim 1.0$. At lower energies, the spectrum of N157B presents marginal evidence for emission lines, which if real most likely arise in hot gas of the diffuse emission region. The hot gas has a characteristic thermal temperature of 0.4-0.7 keV. No significant periodic signal is detected from N157B in the period range of $3 \times 10^{-3}-2000$ s. The pulsed fraction is $\lesssim 9$ (99% confidence) in the $2-7$ keV range. We discuss the nature of the individual X-ray components. In particular, we suggest that the synchrotron radiation of relativistic particles from a fast-moving ($\sim 10^3 km s^{-1}$) pulsar explains the size, morphology, spectrum, and energetics of the comet-shaped X-ray feature. We infer the age of the remnant as $\sim 5 \times 10^3$ yrs. The lack of radio polarization of the remnant may be due to Faraday dispersion by foreground \ion{H}{2} gas.Comment: To be published in The Astrophysical Journal, 21 pages, plus 11 images in the PS, GIF, or jpeg format. Postscript files of images are available at http://www.astro.nwu.edu/astro/wqd/paper/n157b