29 research outputs found

    Microstructural and Dielectric Properties of Ni-Zn and Li-Ni-Zn Ferrites by Impedance Spectroscopy.

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    The real and imaginary parts of the complex impedances and the loss angle (8) of iO.5Zn05Fe20, and (Lioleo.5)O.5Nio.2ZnO.3 Fe20, ferrites were measured at 300 K in the frequency range of 1 - 10 MHz using a frequency response analyser. The complex - plane impedance spectra of the samples are associated with equivalent circuits composed of resistive and capacitive elements due to the bulk (grain) and the grain boundary components. The measured and simulated impedances were analysed using the complex nonlinear least square (CNLS) fitting method. The simulated components of the circuit are interpreted as the characteristic parameters of the microstructural properties of the materials. Microstructural properties are complemented by a morphological study using a scanning electron microscope. The dielectric properties at low and high frequency regimes are interpreted as mainly due to the interfacial and orientational polarizations respectively. A region of negative capacitances at low frequencies is observed for both samples. Frequency dependence of the characteristic parameters of the microstructural components and the dielectric behaviour of the materials are discussed

    Functional MRI characteristics in visual cortex (BA 17, 18 and 19) corresponding to the visual field of normal, glaucoma suspect (GS) and primary open angle glaucoma (POAG) patients

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    The purpose of this study was to characterize, differentiate and correlate visual field and brain activation in visual cortex for normal, glaucoma suspect (GS) and primary open angle glaucoma (POAG) participants using Standard Automated Perimetry (SAP) and functional Magnetic Resonance Imaging (fMRI) respectively. The fMRI scans and SAP test were both carried out in Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM). Two types of black-and-white checkerboard pattern were displayed to the participants during the fMRI scans. The fMRI data were analyzed using WFU pickatlas toolbox targeting visual cortex area. The results showed that there was no significant difference in number of activated voxel between the three groups in visual cortex (BA 17, 18 and 19) while viewing all the given stimuli (p > 0.05). The pattern standard deviation (PSD) of SAP for visual field also revealed no significant differences (p > 0.05) in all groups of participants. However, negative correlation between PSD and fMRI activation was observed. The PSD values increased with a decrease in fMRI activation. With reference to visual field analysis, the results suggest that glaucomatous neuropathy of POAG patients has led to a gradual decrease in visual cortex activation and a gradual increase in PSD

    Noise and Cognitive Performance in Developing Brain using Functional MRI: A scoping review protocol

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    This protocol aims to guide the process to conduct a scoping review on noise and cognitive performance in developing the brain using functional MRI. This review benefits future research by providing a clear mapping of evidence. This protocol adhered to Arksey and O'Malley's scoping review methodological framework. A Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) extension for Scoping Reviews (PRISMA-ScR) was implemented to report the full scoping review. This protocol facilitated a well-structured mapping of evidence. The findings from scoping review will be made public through conferences and journal publications. Keywords: Scoping review protocol; Adolescents’ cognitive performance; Noise; functional MRI. eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v7i19.325

    Optimization of number of scans for a sparse temporal sampling (STS) functional magnetic resonance imaging (fMRI)

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    High sensitivity signal detection for a sparse temporal sampling (STS) functional magnetic resonance imaging (fMRI) is compensated by the increase in the number of scans (Ns) and consequently the scan time. A long scan time would result in fatigue and restlessness in participants, while a short scan time is undesirable for an STS-fMRI due to insufficient Ns for averaging. The purpose of this study was to determine the Ns practically sufficient for a sparse fMRI study. Eighteen participants were presented with white noise during a sparse fMRI scan. The height extent of activation was determined via t statistics and region of interest (ROI) based percentage of signal change (PSC). The t statistics and PSC for Heschl’s gyrus (HG) and superior temporal gyrus (STG) during which the participants listened to the white noise were calculated for different number of scans which were 6, 12, 18, 24, 30 and 36. The t statistics and PSC values calculated for the bilateral HG and STG qualitatively indicated a minimal change over Ns = 12 to 36. Both ROIs showed a consistent common right lateralization of activation for all Ns, indicating the right-hemispheric dominance of auditory cortex in processing white noise stimulus. It was proposed that for a sparse fMRI study, Ns may practically fall between 12 and 36

    Kesan penuaan ke atas kehubungan berkesan otak semasa pemprosesan persepsi pertuturan daripada perspektif pemodelan sebab dan akibat dinamik: satu kajian fMRI

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    Proses penuaan seringkali dikaitkan dengan kemerosotan pada sistem kognitif. Kemerosotan kognitif bermula seawal usia dua puluhan dan berterusan secara linear. Selain itu, kemerosotan kognitif juga menjadi lebih nyata dengan kehadiran hingar latar. Walau bagaimanapun, kesan penuaan ke atas mekanisme pemprosesan persepsi pertuturan menggunakan tugasan mengulang secara terus (FRT) dalam senyap dan hingar belum difahami dengan jelas. Dalam kajian ini, pengimejan resonans magnet kefungsian (fMRI) digunakan untuk membandingkan kesan penuaan ke atas kehubungan efektif otak yang terhasil daripada tugasan FRT ke atas subjek normal dengan empat kumpulan umur yang berlainan iaitu 20 - 29 tahun (n = 15), 30 - 39 tahun (n = 15), 40 - 49 tahun (n = 10) dan 50 - 65 tahun (n = 14). Satu siri lima perkataan yang diselang-seli dalam keadaan hingar dengan senyap diberikan secara auditori. Pemetaan statistik berparameter (SPM8) dan pemodelan dinamik penyebab (DCM10) digunakan untuk menentukan kehubungan efektif otak. Kawasan yang terlibat dalam pembinaan model kehubungan efektif otak adalah STG, HG dan PCG. Model optimum yang dipilih dalam kajian ini adalah model yang menunjukkan keseimbangan antara ketepatan dan kesukaran. Keputusan fMRI kehubungan efektif menunjukkan bahawa komunikasi antara intrahemisfera tidak berubah dengan menggunakan tugasan FRT ini apabila seseorang semakin berusia, tetapi komunikasi antara interhemisfera menjadi semakin kompleks

    Comparison of Resting-State Brain Activation between Healthy Normal and Low Auditory-Verbal Working Memory Capacity Participants

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    Working memory (WM) capacity is the ability to maintain attention and store information briefly in the mind. However, each individual has a limited WM capacity that varies from one person to another. An individual can be categorized as having either normal or low WM capacity. This study aimed to evaluate and compare brain activations of healthy individuals with low and normal auditory-verbal WM capacity. A total of 39 healthy male young adults were recruited from local universities for this study. They were categorized into the normal and low auditory-verbal WM capacity group based on their score in the Malay Version of Auditory Verbal Learning Test (MVAVLT). All participants underwent resting-state functional magnetic resonance imaging (rs-fMRI) scans. The functional data were analyzed using Statistical Parametric Mapping (SPM) and Wake Forest University (WFU) Pickatlas softwares. Brain activations and resting-state amplitude fluctuation (RsAF) were contrasted between groups to determine whether there were any significant differences caused by the different auditory-verbal WM capacity. The findings indicated that the low auditory-verbal WM capacity group showed significantly higher cortical activations in the left lingual gyrus, bilateral middle temporal gyrus, left calcarine, left superior frontal gyrus, and left precuneus as compared to normal auditory-verbal WM capacity group. It is suggested that the higher activation of these brain areas in low verbal-auditory WM capacity participants was attributed to the lower neural adaptability of the brain at rest

    Brain activation display functional asymmetry in response to action, background and tonal frequency during a pitch memory processing: an fMRI study

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    In this study, the asymmetry of the main effects of action, background and tonal frequency during a pitch memory processing were investigated by means of brain activation. Eighteen participants (mean age 27.6 years) were presented with low and high frequency tones in quiet and in noise. They listen, discriminate and recognize the target tone against the final tone in a series of four distracting tones. The main effects were studied using the analysis of variance (ANOVA) with action (to wring (rubber bulb) vs. not to wring), background (in quiet vs. in noise) and frequency (low vs. high) as the factors (and levels respectively). The main effect of action is in the right pre-central gyrus (PCG), in conformation with its contralateral behavior. The main effect of background indicated the bilateral primary auditory cortices (PAC) and is right lateralized, attributable to white noise. The main effect of frequency is also observed in PAC but bilaterally equal and attributable to low frequency tones. Despite the argument that the temporo-spectral lateralization dichotomy is not especially rigid as revealed by the main effect of frequency, right lateralization of PAC for the respective main effect of background clearly demonstrates its functional asymmetry suggesting different perceptual functionality of the right and left PAC

    Resting state effective connectivity between inferior parietal lobe (IPL) and inferior temporal gyrus (ITG) in the left and right hemispheres

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    Inferior parietal lobule (IPL) and inferior temporal gyrus (ITG) are two important brain regions for the default mode network (DMN). IPL has been known to be involved in the control of attention and responding to given information while ITG is involved in the processing and perception awakened by visual stimuli. These two key DMN regions are highly interconnected as determined from white matter and fiber tracking studies. However, little is known about their nature of connectivity while the brain is at rest, whether it is linear, bilinear or nonlinear and whether it is of mono- or bi-direction. Resting state functional magnetic resonance imaging (rsfMRI) data were obtained from 7 healthy male and female participants (average age = 20.7 ± 4.5 years) and were concatenated. Data were analyzed using statistical parametric mapping (SPM12). Endogenous brain signals were modelled by Fourier series at 0.01 – 0.08 Hz. IPL-ITG connected linear, bilinear and non-linear causal models in both hemispheres were constructed and estimated by means of stochastic dynamic causal modelling (sDCM) and were compared using Bayesian Model Selection (BMS) for group studies. Group fixed-effects results indicated that bilateral IPL and ITG exhibited high neural activity at a corrected significant level (pFWE 1000) which has the best balance between model accuracy and difficulty. The minimum free energy (F) = -4.41 × 104 and -4.09 × 104 for left and right hemisphere bilinear models respectively. From BMS and DCM results, it was found that IPL and ITG do have a dynamic collaboration between each other, a connectivity that belongs to a greater network when the brain is at rest. The intrinsic connections between them are negative in both directions i.e. IPL and ITG mutually inhibited each other. The effective connectivity was modulated by the endogenous fluctuation of the brain signal

    Kesan daya dan laju tepikan jari ke atas pengaktifan korteks berkaitan motor

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    Kajian pengimejan resonans magnet kefungsian (fMRI) subjek tunggal ini menyelidiki kesan daya dan laju tepikan ke atas sifat pengaktifan korteks berkaitan motor semasa tepikan jari rentak sendiri secara bilateral. Subjek melakukan empat cara tepikan jari rentak sendiri iaitu sentuh-perlahan (SP), sentuh-laju (SL), tekan-perlahan (TP) dan tekan-laju (TL) dalam satu imbasan fMRI. Model linear am (GLM) digunakan dalam penjanaan pengaktifan otak. Pentaakulan statistik kemudiannya dibuat mengenai pengaktifan otak menggunakan teori medan rawak (RFT) Gaussian pada aras keertian diperbetulkan (α = 0.05), dengan andaian tiada pengaktifan berlaku. Keputusan mendapati otak mengkoordinasi tepikan jari bilateral rentak sendiri dengan penglibatan korteks berkaitan motor iaitu girus presentral (PCG) bilateral, serebelum bilateral dan juga kawasan motor tambahan (SMA). Peningkatan daya tepikan menonjolkan pengaktifan yang bererti (p < 0.05 diperbetulkan) pada PCG bilateral (Kawasan Brodmann (BA) 6) sejajar dengan fungsinya dalam mencetus tindakan motor seperti mengawal daya tepikan. Peningkatan laju tepikan pula menyebabkan peningkatan pengaktifan otak secara bererti (p < 0.05 diperbetulkan) hanya pada korteks kesatuan somatoderia iaitu pada lobus parietal superior (SPL) kanan atau BA7 kanan. Ini mencadangkan bahawa SPL memainkan peranan penting dalam mengkoordinasi pergerakan berkemahiran terancang

    Anomalous temperature dependence of electrical resistivity in Mg0.6Zn0.4Fe2O4 ferrite

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    The electrical resistivity of Mg0.6Zn0.4Fe2O4 ferrite was measured as a function of temperature in the range 300-630 K. Two anomalies are observed in the resistivity curves for measurements during heating up. These anomalies are identified as a magnetic anomaly at the Neel temperature, TN = 598 K, while the other one at TOt = 445 K is discussed as due to the contribution of conduction from the tetrahedral sites. The anomaly at Tot was reduced in the measurements during recooling, while the anomaly at TN was disappeared completely during recooling and second cycle. These effects are discussed as due to the increase of Fe2+ ions at the octahedral sites as a result of cation redistribution at higher temperatures. A relatively small anomaly at Tot still can be observed during the second run. This is possible if the Fe2+ ions have a preference to be relocated at the tetrahedral sites at lower temperatures
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