868 research outputs found

    BGSU Football Media Guide 1980

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    Media guide for Bowling Green State University\u27s 1980-1981 football season.https://scholarworks.bgsu.edu/football_press_guides/1040/thumbnail.jp

    Fabrication of (Polymer Blend-magnesium Oxide) Nanoparticle and Studying their Optical Properties for Optoelectronic Applications

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    Nanocomposites used in many optical devices applications. This aims to preparation of new type of polymer and study their optical properties. The polyvinyl pyrrolidone-carboxymethyl cellulose blend and magnesium oxide nanocomposites have been fabricated. The nanocomposites are prepared for different concentrations of polymer blend and magnesium oxide nanoparticles. The optical properties of nanocomposites were studied. The experimental results showed that the absorbance, absorption coefficient, refractive index, extinction coefficient, real and imaginary parts of dielectric constant and optical conductivity of (PVP-CMC) blend are increased with increase of the MgO nanoparticles concentration. The transmittance and energy band gap are decreased with increase of the MgO nanoparticles concentration. The nanocomposites have high absorbance in UV region which may be used for radiation shielding application

    A Belief Rule Based Expert System for Datacenter PUE Prediction under Uncertainty

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    A rapidly emerging trend in the IT landscape is the uptake of large-scale datacenters moving storage and data processing to providers located far away from the end-users or locally deployed servers. For these large-scale datacenters, power efficiency is a key metric, with the PUE (Power Usage Effectiveness) and DCiE (Data Centre infrastructure Efficiency) being important examples. This article proposes a belief rule based expert system to predict datacenter PUE under uncertainty. The system has been evaluated using real-world data from a data center in the UK. The results would help planning construction of new datacenters and the redesign of existing datacenters making them more power efficient leading to a more sustainable computing environment. In addition, an optimal learning model for the BRBES demonstrated which has been compared with ANN and Genetic Algorithm; and the results are promising

    Age and gender variations in the cone-beam computed tomographic location of mandibular canal : implications for mandibular sagittal split osteotomy

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    Mandibular sagittal split osteotomy (MSSO) may incur unfavorable split and sensorineural injuries. Knowledge of the anatomic location of the mandibular canal (MC) and bone thickness in the region of interest for MSSO, and the possible variations by age and gender can assist in avoiding such complications. Purpose: To study the location of the MC and bone thickness in the region of MSSO by cone-beam computed tomography (CBCT) radiographs and to evaluate the possible variations by age and gender in a Jordanian population. This retrospective radio-anatomical study examined all CBCT radiographs for patients treated over three years at the University of Jordan Hospital, Amman, Jordan. Distances from the MC to the cortical external surfaces and MC diameter (MCD) were measured by a reliable observer at three predetermined regions for MSSO: region (A) [mandibular foramen area], region (B) [mandibular angle area] and region (C) [directly mesial to the second molar]. Gender and age differences in all measurements were then compared using non-parametric Mann-Whitney U test. The final study radiographs comprised a total of 202 CBCT belonged to a cohort of 202 subjects; 91 males (45.1%) and 111 (54.9%) females, with mean age (Ā± SD) of 42.94 Ā± 18.54 years (range 18?90 years). Whereas only the bone thickness superior, buccal and inferior to MC in regions (B) and (C), and MCD in the three regions exhibited significant (p< 0.05) gender differences, all measured distances exhibited statistically significant (p< 0.05) differences between young and adult patients. The location of MC and bone thickness in the region of MSSO were significantly variable according to age, but exhibited sexual diamorphism only in regions (B) and (C). This fundamental knowledge should be considered during MSSO planning

    Multidetector Computed Tomography Findings of a Papillary Fibroelastoma of the Aortic Valve: A Case Report

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    Papillary fibroelastoma is a rare benign cardiac tumor that represents 10% of all primary cardiac tumors. Diagnosis is accomplished incidentally by echocardiography that is usually performed for another purpose. Most papillary fibroelastomas are asymptomatic, but the lesions are recognized as a cause of embolisms. To the best of our knowledge, there has been no case report of computed tomography findings of a papillary fibroelastoma. We report a case of a papillary fibroelastoma in a 78-yr-old woman who had dyspnea and chest tightness. Echocardiography revealed a small lobulated mobile echogenic mass attached to the aortic valve, and CT demonstrated a lobulated soft tissue density mass with a thin stalk at the sinotubular junction of the aortic valve

    Arsenic Exposure and Age- and Sex-Specific Risk for Skin Lesions: A Population-Based Caseā€“Referent Study in Bangladesh

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    BACKGROUND: The objective of this population-based caseā€“referent study in Matlab, Bangladesh, was to assess the susceptibility to arsenic-induced skin lesions by age and sex, in a population drinking water from As-contaminated tube wells. METHODS: Identification of As-related skin lesions was carried out in three steps: a) screening of the entire population > 4 years of age (n = 166,934) by trained field teams; b) diagnosis of suspected As-related cases by physicians; and c) confirmation by experts based on physiciansā€™ records and photographs. A total of 504 cases with skin lesions were confirmed. We randomly selected 2,201 referents from the Matlab health and demographic surveillance system; 1,955 were eligible, and 1,830 (94%) were available for participation in the study. Individual history of As exposure was based on information obtained during interviews and included all drinking-water sources used since 1970 and concentrations of As (assessed by atomic absorption spectrophotometry) in all the tube wells used. RESULTS: Cases had been exposed to As more than referents (average exposure since 1970: male cases, 200 Ī¼g/L; female cases, 211 Ī¼g/L; male referents, 143 Ī¼g/L; female referents, 155 Ī¼g/L). We found a doseā€“response relationship for both sexes (p < 0.001) and increased risk with increasing socioeconomic status. Males had a higher risk of obtaining skin lesions than females (odds ratio 10.9 vs. 5.78) in the highest average exposure quintile (p = 0.005). Start of As exposure (cumulative exposure) before 1 year of age was not associated with higher risk of obtaining skin lesions compared to start of As exposure later in life. CONCLUSIONS: The results demonstrate that males are more susceptible than females to develop skin lesions when exposed to As in water from tube wells

    TAT-peptide conjugated repurposing drug against SARS-CoV-2 main protease (3CLpro): potential therapeutic intervention to combat COVID-19

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    The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that originated in Chinese city of Wuhan has caused around 906,092 deaths and 28,040,853 confirmed cases worldwide (WHO, 11 September, 2020). In a life-threatening situation, where there is no specific and licensed anti-COVID-19 vaccine or medicine available; the repurposed drug might act as a silver bullet. Currently, more than 211 vaccines, 80 antibodies, 31 antiviral drugs, 35 cell-based, 6 RNA-based and 131 other drugs are in clinical trials. It is therefore utter need of the hour to develop an effective drug that can be used for the treatment of COVID-19 before a vaccine can be developed. One of the best-characterized and attractive drug targets among coronaviruses is the main protease (3CL^{pro}). Therefore, the current study focuses on the molecular docking analysis of TAT-peptide^{47ā€“57} (GRKKRRQRRRP)-conjugated repurposed drugs (i.e., lopinavir, ritonavir, favipiravir, and hydroxychloroquine) with SARS-CoV-2 main protease (3CL^{pro} to discover potential efficacy of TAT-peptide (TP) - conjugated repurposing drugs against SARS-CoV-2. The molecular docking results validated that TP-conjugated ritonavir, lopinavir, favipiravir, and hydroxychloroquine have superior and significantly enhanced interactions with the target SARS-CoV-2 main protease. In-silico approach employed in this study suggests that the combination of the drug with TP is an excelling alternative to develop a novel drug for the treatment of SARS-CoV-2 infected patients. The development of TP based delivery of repurposing drugs might be an excellent approach to enhance the efficacy of the existing drugs for the treatment of COVID-19. The predictions from the results obtained provide invaluable information that can be utilized for the choice of candidate drugs for in vitro, in vivo and clinical trials. The outcome from this work prove crucial for exploring and developing novel cost-effective and biocompatible TP conjugated anti-SARS-CoV-2 therapeutic agents in immediate future
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