173 research outputs found

    Saliency-based image enhancement

    Get PDF
    Ph.DDOCTOR OF PHILOSOPH

    Saliency-aware Stereoscopic Video Retargeting

    Full text link
    Stereo video retargeting aims to resize an image to a desired aspect ratio. The quality of retargeted videos can be significantly impacted by the stereo videos spatial, temporal, and disparity coherence, all of which can be impacted by the retargeting process. Due to the lack of a publicly accessible annotated dataset, there is little research on deep learning-based methods for stereo video retargeting. This paper proposes an unsupervised deep learning-based stereo video retargeting network. Our model first detects the salient objects and shifts and warps all objects such that it minimizes the distortion of the salient parts of the stereo frames. We use 1D convolution for shifting the salient objects and design a stereo video Transformer to assist the retargeting process. To train the network, we use the parallax attention mechanism to fuse the left and right views and feed the retargeted frames to a reconstruction module that reverses the retargeted frames to the input frames. Therefore, the network is trained in an unsupervised manner. Extensive qualitative and quantitative experiments and ablation studies on KITTI stereo 2012 and 2015 datasets demonstrate the efficiency of the proposed method over the existing state-of-the-art methods. The code is available at https://github.com/z65451/SVR/.Comment: 8 pages excluding references. CVPRW conferenc

    A New Dataset and Transformer for Stereoscopic Video Super-Resolution

    Full text link
    Stereo video super-resolution (SVSR) aims to enhance the spatial resolution of the low-resolution video by reconstructing the high-resolution video. The key challenges in SVSR are preserving the stereo-consistency and temporal-consistency, without which viewers may experience 3D fatigue. There are several notable works on stereoscopic image super-resolution, but there is little research on stereo video super-resolution. In this paper, we propose a novel Transformer-based model for SVSR, namely Trans-SVSR. Trans-SVSR comprises two key novel components: a spatio-temporal convolutional self-attention layer and an optical flow-based feed-forward layer that discovers the correlation across different video frames and aligns the features. The parallax attention mechanism (PAM) that uses the cross-view information to consider the significant disparities is used to fuse the stereo views. Due to the lack of a benchmark dataset suitable for the SVSR task, we collected a new stereoscopic video dataset, SVSR-Set, containing 71 full high-definition (HD) stereo videos captured using a professional stereo camera. Extensive experiments on the collected dataset, along with two other datasets, demonstrate that the Trans-SVSR can achieve competitive performance compared to the state-of-the-art methods. Project code and additional results are available at https://github.com/H-deep/Trans-SVSR/Comment: Conference on Computer Vision and Pattern Recognition (CVPR 2022

    HbA2 levels in β-thalassaemia carriers with the Filipino β0-deletion: are the levels higher than what is found with non-deletional forms of β0-thalassaemia?

    Get PDF
    AIMS: Classical carriers of β-thalassaemia are identified by a raised HbA2 level. Earlier studies indicated that the Filipino β-deletion has high raised HbA2 levels. The introduction of automated high performance liquid chromatography (HPLC) for thalassaemia screening is an important advance in technology for haematology laboratories. The BioRad Variant II Hb analyser is a common instrument used to quantify HbA2 levels in thalassaemia screening. This study aimed to determine HbA2 levels in carriers of Filipino β-mutation using the BioRad Variant II Hb analyser. METHODS: The Filipino β-deletion was identified using gap-polymerase chain reaction (PCR) in the parents of transfusion dependent β-thalassaemia patients who were homozygous for the Filipino β-deletion in the indigenous population of Sabah, Malaysia. Hb subtypes were quantified on the BioRad Variant II Hb analyser. Concurrent α-thalassaemia was identified by multiplex gap-PCR for deletions and amplification refractory mutation system (ARMS)-PCR for non-deletional mutations. RESULTS: The mean HbA2 level for Filipino β-thalassaemia trait was 5.9 ± 0.47 and with coinheritance of α-thalassaemia was 6.3 ± 0.44 (-α heterozygous) and 6.7 ± 0.36 (-α homozygous). The HbA2 levels were all >4% in keeping with the findings of classical β-thalassaemia trait and significantly higher than levels seen in non-deletional forms of β-thalassaemia. CONCLUSION: The HbA2 level measured on the BioRad Variant II Hb analyser was lower than the level in the first description of the Filipino β-thalassaemia. β-thalassaemia trait with coinheritance of α-thalassaemia (-α) is associated with significantly higher HbA2 level

    Haplotype analysis of β-Thalassaemia major and carriers with Filipino β°-deletion in Sabah, Malaysia

    Get PDF
    Objective: The Filipino β°-deletion has been reported as a unique mutation in East Malaysia with a severe phenotype due to the complete absence of β-globin chain synthesis. In this study, the haplotype patterns of the β-globin gene cluster were used to relate the human genetic variation to this specific β-thalassaemia mutation. Methods: The 376 study subjects included 219 β-thalassaemia major (β-TM) patients with homozygous Filipino β°-deletion and 157 carriers with heterozygous Filipino β°-deletion from 10 government hospitals in different regions of Sabah. Genomic DNA was isolated from whole blood using silica membrane based DNA purification protocol. Polymerase chain reaction restriction fragment length polymorphism analysis (PCR-RFLP) was conducted on five markers within the β-globin gene cluster to construct the haplotype patterns.Results: Four haplotypes (Haplotype I–IV) were identified with Haplotype I as the predominant haplotype with the highest frequency of 0.98, followed by Haplotype II, III and Haplotype IV with 0.02. Haplotype I was strongly linked with the Filipino β°-deletion among the indigenous population. Conclusion: Haplotype I as the predominant haplotype suggests the patients with the Filipino β°-deletion in Sabah have a similar origin

    Immunopathological Roles of Cytokines, Chemokines, Signaling Molecules, and Pattern-Recognition Receptors in Systemic Lupus Erythematosus

    Get PDF
    Systemic lupus erythematosus (SLE) is an autoimmune disease with unknown etiology affecting more than one million individuals each year. It is characterized by B- and T-cell hyperactivity and by defects in the clearance of apoptotic cells and immune complexes. Understanding the complex process involved and the interaction between various cytokines, chemokines, signaling molecules, and pattern-recognition receptors (PRRs) in the immune pathways will provide valuable information on the development of novel therapeutic targets for treating SLE. In this paper, we review the immunopathological roles of novel cytokines, chemokines, signaling molecules, PRRs, and their interactions in immunoregulatory networks and suggest how their disturbances may implicate pathological conditions in SLE

    Learning Image Aesthetics by Learning Inpainting

    Get PDF
    Due to the high capability of learning robust features, convolutional neural networks (CNN) are becoming a mainstay solution for many computer vision problems, including aesthetic quality assessment (AQA). However, there remains the issue that learning with CNN requires time-consuming and expensive data annotations especially for a task like AQA. In this paper, we present a novel approach to AQA that incorporates self-supervised learning (SSL) by learning how to inpaint images according to photographic rules such as rules-of-thirds and visual saliency. We conduct extensive quantitative experiments on a variety of pretext tasks and also different ways of masking patches for inpainting, reporting fairer distribution-based metrics. We also show the suitability and practicality of the inpainting task which yielded comparably good benchmark results with much lighter model complexit

    Molecular basis of transfusion dependent beta-thalassemia major patients in Sabah

    Get PDF
    Beta-thalassemia is one of the most prevalent inherited diseases and a public health problem in Malaysia. Malaysia is geographically divided into West and East Malaysia. In Sabah, a state in East Malaysia, there are over 1000 estimated cases of β-thalassemia major patients. Accurate population frequency data of the molecular basis of β-thalassemia major are needed for planning its control in the high-risk population of Sabah. Characterization of β-globin gene defects was done in 252 transfusion dependent β-thalassemia patients incorporating few PCR techniques. The study demonstrates that β-thalassemia mutations inherited are ethnically dependent. It is important to note that 86.9% of transfusion-dependent β-thalassemia major patients in Sabah were of the indigenous population and homozygous for a single mutation. The Filipino β0-deletion was a unique mutation found in the indigenous population of Sabah. Mutations common in West Malaysia were found in 11 (4.3%) patients. Four rare mutations (Hb Monroe, CD 8/9, CD 123/124/125 and IVS I-2) were also found. This study is informative on the population genetics of β-thalassemia major in Saba

    Re-cycling paradigms: cell cycle regulation in adult hippocampal neurogenesis and implications for depression

    Get PDF
    Since adult neurogenesis became a widely accepted phenomenon, much effort has been put in trying to understand the mechanisms involved in its regulation. In addition, the pathophysiology of several neuropsychiatric disorders, such as depression, has been associated with imbalances in adult hippocampal neurogenesis. These imbalances may ultimately reflect alterations at the cell cycle level, as a common mechanism through which intrinsic and extrinsic stimuli interact with the neurogenic niche properties. Thus, the comprehension of these regulatory mechanisms has become of major importance to disclose novel therapeutic targets. In this review, we first present a comprehensive view on the cell cycle components and mechanisms that were identified in the context of the homeostatic adult hippocampal neurogenic niche. Then, we focus on recent work regarding the cell cycle changes and signaling pathways that are responsible for the neurogenesis imbalances observed in neuropathological conditions, with a particular emphasis on depression
    corecore