119 research outputs found

    Hemispheric asymmetry in the efficiency of attentional networks

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    Advantage in conflict resolution was observed, which may indicate hemispheric asymmetry of the executive network. No VF effect for alerting was found. The results, consistent with the common notion of general right hemisphere dominance for attention, provide a more detailed account of hemispheric asymmetries of the attentional networks than previous studies using the LANT task

    Design, Analysis and Comparison of Si- and GaN-Based DC-DC Wide-Input-Voltage-Range Buck-Boost Converters

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    The purpose of the article is a comparison between┬áDC/DC topologies with a wide input voltage range. The┬áresearch also explains how the implementation of┬áGaN┬áEÔÇĹHEMT transistors influences the overall efficiency of┬áthe┬áconverter. The article presents a process of selection of the most efficient topology for stabilization of the battery storage voltage (9 V ÔÇô 36 V) at┬áthe┬álevel of 24 V, which enables the usage of ultracapacitor energy storage in a wide range of applications, e.g., in automated electric vehicles. In order to choose the most suitable topology, simulation and laboratory research were conducted. The two most promising topologies were selected for verification in the experimental model. Each of the converters was constructed in two versions: with Si and with GaN E-HEMT transistors. The paper presents experimental research results that consist of┬áprecise power loss measurements and thermal analysis. The┬áperformance with an increased switching frequency of┬áconverters was also examined

    Digital video recording techniques and chemical experiment in modern media

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    W artykule przedstawiono wykorzystanie nowoczesnych technologii informatycznych do prezentacji eksperyment├│w chemicznych. Opisano zastosowanie technik cyfrowych do realizacji film├│w edukacyjnych z chemii. Zaprezentowano zalety technologii internetowych oraz wykorzystanie urz─ůdze┼ä mobilnych w nauczaniu chemii. Om├│wiono zastosowanie naturalnego interfejsu u┼╝ytkownika jakim jest Kinect do tworzenia wirtualnego laboratorium chemicznego. Zestawiono wyniki bada┼ä nad przydatno┼Ťci─ů edukacyjn─ů opisanych ┼Ťrodk├│w dydaktycznych.This article presents the use of modern information technology to present chemistry experiments. It describes the way in which digital technologies can be used to facilitate the implementation of educational videos in chemistry and presents the advantages of Internet technology as well as the use of mobile devices in teaching chemistry. This article also discusses the use of a natural user interface, that is, Kinect in relation to creating a virtual chemical laboratory and summarizes the results of studies on the educational usefulness of these didactic measures.351031207Neodidagmat

    Asymetria m├│zgu i lateralizacja w j─ůkaniu

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    The diagnosis of developmental disorders ÔÇô including those of speech fluency ÔÇô have traditionally emphasized the meaning of atypical laterality. In the present paper we review briefly the literature showing that, even though stutter-ing, along with other language deficiencies, is indeed related to atypical brain asymmetry, the exact nature of this relation remains elusive, and the diagnostic utility of laterality measurement seems disputable.W diagnozie zaburze┼ä rozwojowych ÔÇô w tym tak┼╝e zaburze┼ä p┼éyn-no┼Ťci mowy ÔÇô tradycyjnie przywi─ůzuje si─Ö du┼╝─ů wag─Ö do atypowej lateralizacji. Artyku┼é zawiera pobie┼╝ny przegl─ůd literatury, pokazuj─ůcy, ┼╝e cho─ç j─ůkanie, podob-nie jak inne zaburzenia sprawno┼Ťci j─Özykowej, faktycznie wi─ů┼╝e si─Ö z nietypow─ů asymetri─ů m├│zgu, to natura tego zwi─ůzku pozostaje wci─ů┼╝ niejasna, a warto┼Ť─ç diagnostyczna badania lateralizacji budzi w─ůtpliwo┼Ťci.

    Chorionic thickness and PlGF concentrations as early predictors of small-for-gestational age birth weight in a low risk population

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    Objectives: SGA is associated with higher incidence of postnatal complications, including suboptimal neurodevelopment and increased cardiovascular risk. Screening for SGA, carried out at 11ÔÇô13 (+ 6d) gestational weeks enables to reduce or completely eliminate the above mentioned complications. The aim of this study was to assess the correlation between chorionic thickness, concentration of PIGF protein and foetal birth weight in a single low-risk pregnancy. Material and methods: The study included 76 patients at 11ÔÇô13 (+ 6d) gestational weeks, monitored throughout preg┬şnancy. Ultrasound examinations identified the location and thickness of the chorion by measuring it in its central part at its widest point in a sagittal section. Additionally, at each visit venous blood was collected to determine the level of PlGF, PAPP-A, and BhCG. Results: A significant positive correlation (r = 0.37) was found between the foetal weight and chorionic thickness. This correlation was affected by the location of the chorion and a significant negative correlation was observed between the level of PLGF, FHR, weight and length of the newborn. Maternal early-pregnancy BMI did not affect neonatal weight and body length, FHR, chorionic thickness, and the levels of PlGF, PAPP-A, and BhCG. Conclusions: The preliminary analysis indicates an association between chorionic thickness assessed during ultrasound at 11ÔÇô13 (+ 6d) gestational weeks, PIGF levels assayed at the same time and birth weight. Increasing chorion thickness was accompanied by increasing foetal birth weight. PlGF level showed an inversely proportional effect on the foetal weight. This correlation was significant for the posterior location of the chorion

    Ocena warto┼Ťci predykcyjnej st─Ö┼╝enia TNF-alfa w surowicy krwi matki w prognozowaniu wrodzonego zaka┼╝enia noworodka oraz zaka┼╝enia matki

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    Introduction: The consequences of uncomplicated PPROM are serious, and the presence of overt intraamniotic infection (IAI) is associated with a significant increase in both, the maternal and fetal morbidity and mortality rate. TNF-alpha is a cytokine involved in systemic inflammation and plays an important role in modulating the acute phase reaction. Aim: the aim of this study was to evaluate the predictive value of tnf-alpha levels in maternal serum within 6 hours after pprom and in the period of up to 12 hours after delivery, in the prediction of neonatal and maternal infection. Material and methods: The investigation was conducted on a group of 56 women diagnosed with PPROM between 30+0 and 36+6 weeks gestational age. In the period of up to 6hrs from pprom first sample of 10ml of maternal venous blood for laboratory testing was taken and the level of tnf-alpha was measured. A second sample of venous blood was taken within 12hrs from delivery to reassess the tnf-alpha levels. All the participants were divided retrospectively into four groups depending on the occurrence of adverse neonatal and maternal outcome. Measuring the concentration of tnf-alpha in maternal serum was performed using the elisa method (enzymelinked immunosorbent assay). Results: A statistically significant difference in the second assay (up to 12 hours after delivery) between the patients with and without signs of maternal infection was observed concerning the tnf-alpha serum level. The concentration of this cytokine in maternal serum after delivery was 1.79 and 1.36 pg/ml (pWst─Öp: Konsekwencje niepowik┼éanego PPROM s─ů powa┼╝ne, a dodatkowo obecno┼Ť─ç jawnej klinicznie IAI zwi─ůzana jest ze znacz─ůcym wzrostem zachorowalno┼Ťci i ┼Ťmiertelno┼Ťci matki i noworodka. TNF-alfa jest cytokin─ů bior─ůc─ů udzia┼é w reakcji zapalanej oraz odgrywa istotn─ů rol─Ö w modulacji reakcji ostrej fazy. Cel: Celem pracy by┼éa ocena warto┼Ťci predykcyjnej oznaczenia st─Ö┼╝enia TNF-alfa w surowicy krwi matki w czasie 6 godzin od PPROM oraz 12 godzin od porodu w prognozowaniu zaka┼╝enia matki i noworodka. Materia┼é i metodyka: Badanie przeprowadzono w grupie 56 kobiet z PPROM pomi─Ödzy 30+0 a 36+6 tygodniem ci─ů┼╝y. W okresie do 6 godzin od PPROM wykonano podstawowe badania laboratoryjne oraz zmierzono st─Ö┼╝enie TNF-alfa w surowicy krwi matki. Ponowne oznaczanie analizowanych parametr├│w laboratoryjnych oraz st─Ö┼╝enia TNF-alfa przeprowadzono w czasie do 12 godzin od porodu. Wszystkie w┼é─ůczone do badania pacjentki podzielono retrospektywnie na cztery grupy, w zale┼╝no┼Ťci od wyst─ůpienia niekorzystnego wyniku po┼éo┼╝niczego matki i noworodka. Pomiar st─Ö┼╝enia TNF-alfa w surowicy krwi matki wykonano przy u┼╝yciu metody ELISA. Wyniki: W grupie pacjentek z cechami zaka┼╝enia, st─Ö┼╝enie TNF-alfa w surowicy krwi w okresie do 12 godzin od porodu by┼éo statystycznie wy┼╝sze w por├│wnaniu do grupy kobiet bez cech zaka┼╝enia (1,79 vs. 1,36 pg/ml ÔÇô

    Utrata masy kostnej u pacjentek z nowotworami z┼éo┼Ťliwymi narz─ůd├│w p┼éciowych

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    Nowadays, women with genital cancers live longer due to early diagnosis and better treatment schemes. Only few studies assessed bone mass in patients with genital cancer. Osteoporosis is a condition characterized by progressive loss of bone mass, weakening of the spatial structure of the bone, and increased susceptibility to fractures. Osteopenia is a condition of reduced, but not yet reaching the pathological values, bone density in relation to norms for age and sex. Metastases are the primary cause of death in cancer patients. It is estimated that approximately half of people dying due to cancer have bone metastases. Osteoporosis in neoplastic disease may occur due to bone metastases or therapy-related adverse effects, i.e. reduced bone mineral density (BMD). Bone microenvironment provides a good medium for the growth of cancer cells. BMD of the femur and spine should be measured by DXA. Computed tomography (CT) and magnetic resonance imaging (MRI) are the techniques used to detect bone metastases. Lifestyle is the key to improving the quality of life and maximize any pharmacological treatment in cancer patients. It is proposed that treatment of cancer without bone metastases does not require therapy increasing bone mass. Further studies in women treated for gynecological malignancies undergoing oophorectomy and adjuvant treatment are needed to elucidate the mechanisms associated with bone loss.Kobiety z nowotworami narz─ůd├│w p┼éciowych ┼╝yj─ů obecnie d┼éu┼╝ej dzi─Öki cz─Östo wczesnej diagnozie i coraz lepszym schematom leczenia. Niewiele jest bada┼ä, kt├│rych celem by┼éa ocena masy kostnej u chorych na nowotwory narz─ůd├│w p┼éciowych. Osteoporoza to stan chorobowy charakteryzuj─ůcy si─Ö post─Öpuj─ůcym ubytkiem masy kostnej, os┼éabieniem struktury przestrzennej ko┼Ťci oraz zwi─Ökszon─ů podatno┼Ťci─ů na z┼éamania. Osteopenia jest stanem zmniejszonej, w odniesieniu do norm dla p┼éci i wieku, ale jeszcze nieosi─ůgaj─ůcej warto┼Ťci patologicznych g─Östo┼Ťci ko┼Ťci. Podstawow─ů przyczyn─ů zgon├│w pacjent├│w chorych na raka s─ů przerzuty nowotworowe. Ocenia si─Ö, ┼╝e oko┼éo po┼éowa os├│b umieraj─ůcych z powodu nowotworu ma przerzuty do ko┼Ťci. Osteoporoza obserwowana w chorobie nowotworowej mo┼╝e by─ç wynikiem przerzut├│w do ko┼Ťci lub niekorzystnego wp┼éywu terapii zmniejszaj─ůcej g─Östo┼Ť─ç mineraln─ů ko┼Ťci- BMD. Mikro┼Ťrodowisko ko┼Ťci stanowi dobre pod┼éo┼╝e do wzrostu kom├│rek nowotworowych. BMD oceniana z ko┼Ťci udowej i kr─Ögos┼éupa powinna by─ç mierzona przez DXA. Techniki maj─ůce zastosowanie w wykrywaniu przerzut├│w do ko┼Ťci to tomografia komputerowa- CT i rezonans magnetyczny MRI. Styl ┼╝ycia jest kluczowym elementem dla poprawy jako┼Ťci ┼╝ycia i maksymalizacji wszelkiego leczenia farmakologicznego u chorych na raka. Wnioskuje si─Ö, ┼╝e terapia nowotworu bez przerzut├│w do ko┼Ťci nie wymaga leczenia zwi─Ökszaj─ůcego mas─Ö kostn─ů. Potrzebne s─ů dalsze badania u kobiet leczonych z powodu z┼éo┼Ťliwych nowotwor├│w ginekologicznych poddawanych usuni─Öciu jajnik├│w i leczeniu uzupe┼éniaj─ůcemu w celu wyja┼Ťnienia mechanizm├│w zwi─ůzanych z utrat─ů tkanki kostne
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