40,338 research outputs found

    GE MOD-1 noise study

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    Noise studies of the MOD-1 Wind Turbine Generator are summarized, and a simple mathematical noise is presented which is adequate to correlate the sound levels found near the machine. A simple acoustic measure is suggested for use in evaluating far field sound levels. Use of this measure as input to a currently available sound complaint prediction program is discussed. Results of a recent statistical survey relative to the far field variation of this acoustic measure because of atmospheric effects are described

    Improving translational studies: lessons from rare neuromuscular diseases

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    Animal models play a key role in the development of novel treatments for human disease. This is particularly true for rare diseases – defined as disorders that affect less than 1 in 2000 people in the human population – for which, very often, there are no effective methods of treatment. Pharmaceutical companies are increasingly focussing on the development of therapies for the more than 7000 rare diseases. Because the majority of these are the result of single gene disorders, the exceptional ability to manipulate the mouse genome means that many such studies will take place in the laboratory mouse. But how good are the mouse models and how useful are they in assessing the potential for translational medicine? In this Editorial, I will discuss current difficulties in translational research as well as examples of good laboratory practice and guidelines that are being implemented to improve the translational potential of animal studies in the field of neuromuscular rare diseases. This could represent a potentially useful approach for adoption by other disease fields to achieve a greater success rate in translational studies

    Growing Religious Diversity in South Carolina: Implications for the Palmetto State

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    This paper documents the growth of religious diversity in South Carolina, drawing on interviews with members from the traditions represented, previous scholarly research on religion in South Carolina, newspaper articles, census data and interviews with religion reporters and educators across the state. After presenting basic outlines and historical sketchs of each faith in South Carolina, the paper goes on to explore the implications of this growing diversity for a Southern "Bible Belt" state like South Carolina, highlighting controversies over prayer in public schools and at government council meetings and examining discrimination and hate crimes. It also gives attention to the two predominant reactions to religious diversity in South Carolina--the emerging interfaith movement and the attempts to convert members of other religious traditions, suggesting that dialogue needs to take place along this boundary as well as between faiths

    The Issue of Globalization-An Overview

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    [From Summary] In the 1990s, globalization gained widespread usage as a term with many interpretations. Globalism is employed in this report to describe networks of interdependence functioning at multi-continental distances. Globalization is an increase in globalism and de-globalization a reduction. In providing an introductory view of these networks, with an emphasis on contemporary economic factors, a goal of this report is to illustrate how policy consequences, sometimes unintended, may be dispersed via globalized networks. As networks expand and become more intricate there is an opportunity for feedback along previously non-existent linkages

    Reidentifying hardware after loss of serial number

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    System traces fabrication and inspection records of special hardware back to the raw material. Reidentification of hardware, after loss of serial numbers, is established by X raying all parts again and comparing the new film with the original, whose numbers were previously recorded on serialized documents

    In defense of mechanism

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    In Life Itself and in Essays on Life Itself, Robert Rosen (1991, 2000) argued that machines were, in principle, incapable of modeling the defining feature of living systems, which he claimed to be the existence of closed causal loops. Rosen's argument has been used to support critiques of computational models in ecological psychology. This article shows that Rosen's attack on mechanism is fundamentally misconceived. It is, in fact, of the essence of a mechanical system that it contains closed causal loops. Moreover, Rosen's epistemology is based on a strong form of indirect realism and his arguments, if correct, would call into question some of the fundamental principles of ecological psychology

    Expressiveness of Generic Process Shape Types

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    Shape types are a general concept of process types which work for many process calculi. We extend the previously published Poly* system of shape types to support name restriction. We evaluate the expressiveness of the extended system by showing that shape types are more expressive than an implicitly typed pi-calculus and an explicitly typed Mobile Ambients. We demonstrate that the extended system makes it easier to enjoy advantages of shape types which include polymorphism, principal typings, and a type inference implementation.Comment: Submitted to Trustworthy Global Computing (TGC) 2010