20 research outputs found

    Geomorphology, beach classification and seasonal morphodynamic transition of a Mediterranean gravel beach (Sardinia, Gulf of Cagliari)

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    This paper presents an innovative multi-thematic map (1:2500) that integrates morpho-sedimentological data, hydrodynamic processes, seasonal morphodynamic transitions and the distribution of the benthic habitat of a Mediterranean microtidal, wave-dominated gravel beach system. It is part of a larger cartography of coastal areas, and is based on an interdisciplinary sea-land approach that is applicable worldwide and aims to facilitate coastal management practices and future scientific research. The applications to coastal management include: the facilitation of coastal vulnerability assessments; easy-to-access, up-to-date digital geospatial data; and baseline studies for the future assessment and monitoring of environmental changes. The main environmental features that control the marine processes of this gravel beach appear to be linked to geological and morphological contexts such as the presence of the river mouth, the outcropping of a beach-rock along the coastline, the deposition of gravelly sediment in the beachface and the seagrass cover

    Spatial statistics and composite indicators: a review of existing case studies and open research issues on spatial composite indicators

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    Recent research advances in spatial statistic on spatial autocorrelation help to better understand the spatial dependence between spatial units. Understanding this kind of relationships helps to earn better insights on how phenomena are distribute along space and why in a particular location they feature a particular value. In the last decade or so, spatial statistic techniques have been used by several scholars to study the spatial distribution of composite indicators, introducing a new point of view in the study of composite indicators that allows to earn more knowledge with respect to the indicator’s value only; in addition to this, spatial analysis was proven to show, for a particular location, the dependency of the composite from one of its sub-factor. This contribution presents a state of the art review of most recent advances in spatial statistics applied to composite indicators as an early contribution towards a more robust definition and application of spatial composite indicators

    An operational wave system within the monitoring program of a Mediterranean beach

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    This work assesses the performance of an operational wave system in theMediterranean Sea by comparing computed data with measurements collected at different water depths. Nearshore data measurements were collected through a field experiment carried out at Poetto beach (Southern Sardinia, Italy) during spring 2017. In addition to coastal observations, we use intermediate and deep water wave data measured by two buoys: one situated North-West of Corsica and the other in the Gulf of Lion. The operational wave system runs once a day to predict the wave evolution up to five days in advance. We use a multi-grid approach in which a large grid extends over the entire Mediterranean basin and a fine grid covers the coastal seas surrounding the islands of Sardinia and Corsica. The comparison with measurements shows that the operational wave system is able to satisfactorily reproduce the wave evolution in deep and intermediate waters where the relative error of the significant wave height is 17%. The error exceeding 25% in coastal waters suggests that the use of a finer grid and the coupling with an atmospheric model able to catch local effects is advisable to accurately address nearshore wave processes driven by coastal wind forcing

    Natural history of malignant bone disease in gastric cancer: final results of a multicenter bone metastasis survey.

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    BACKGROUND: Bone metastasis represents an increasing clinical problem in advanced gastric cancer (GC) as disease-related survival improves. In literature, few data on the natural history of bone disease in GC are available. PATIENTS AND METHODS: Data on clinicopathology, skeletal outcomes, skeletal-related events (SREs), and bone-directed therapies for 208 deceased GC patients with evidence of bone metastasis were statistically analyzed. RESULTS: Median time to bone metastasis was 8 months (CI 95%, 6.125-9.875 months) considering all included patients. Median number of SREs/patient was one. Less than half of the patients (31%) experienced at least one and only 4 and 2% experienced at least two and three events, respectively. Median times to first and second SRE were 2 and 4 months, respectively. Median survival was 6 months after bone metastasis diagnosis and 3 months after first SRE. Median survival in patients who did not experience SREs was 5 months. Among patients who received zoledronic acid before the first SRE, the median time to appearance of first SRE was significantly prolonged compared to control (7 months vs 4 months for control; P: 0.0005). CONCLUSIONS: To our knowledge, this retrospective analysis is the largest multicenter study to demonstrate that bone metastases from GC are not so rare, are commonly aggressive and result in relatively early onset of SREs in the majority of patients. Indeed, our large study, which included 90 patients treated with ZOL, showed, for the first time in literature, a significant extension of time to first SRE and increase in the median survival time after diagnosis of bone metastasis. Taken together, these data may support the beneficial effects of ZOL in GC patients
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