1,169 research outputs found


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    Although quality of life and facilities are increasing day by day but satisfaction level and mental health are deteriorating globally. Happiness quotient is fallen down and psychosomatic disorders, behavioral and adjustment problems are mushrooming in every sphere of society. Main reason behind all these is negative attitude of persons due to which one becomes pessimist and can’t see the brighter aspects of life. Stressors are always there but it’s the ability of humans to handle the stress which protects them and it comes from positivity in the attitude. In Yogsutra, Maharshi Patanjali clearly mentions that person becomes like his attitudes so one should control the attitude through meditation. Taking this as baseline, a study was conducted on 20 apparently healthy volunteers to assess the effect of meditation practice of Heartfulness Institute’s point A&B meditation to see its transformational efficacy in increment in positivity of Mental Attitude. For this, volunteers were selected randomly and to measure their attitude, LIKERTSCALE is framed and evaluation of attitude was done before and after meditation trial of 21 days. For meditation evaluation, a seven scale criteria is formed to evaluate intensity with which volunteers performed meditation and to record the evidence. After statistical analysis, this meditation practice was found highly significant in changing the human attitude and increasing its positivity. This result is quite enthusiastic after such a short span of trial and may be a landmark in maintaining mental health and quality of life if practiced regularly. It is a nondrug therapy advisable for masses requiring no vigorous training as indicated by the fact that no volunteer was practicing any spiritual practice earlier, they all were novice


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    Nutritive diet has grabbed the center stage in current times among common men as well as researchers &food has turned into a whole damn industry. Despite of everything, Malnutrition is the largest single contributor to diseases in the world & leads to 45% of all deaths in children under 5 in developing countries. Due to interrelated mother- child nutrition, if a breastfeeding mother gets required nutrition, her kid becomes healthy. The causes of improper nutrition are variable but lack of nutritious food combinations in all classes are most important throughout the world. Ayurveda is science of individualistic need based dietetics & nutrition and describes foods accordingly. There is recommendation of a super food named Shigru (Moringa) for Sutika (lactating mothers) in Bheshajyaratnawali,taking this as reference we have conceptualized a food combination of Moringa +wheat flour+ jaggery which is super nutritious and serves as a cheap, affordable, easy to collect and easy to make, palatable preparation. When 11% of the world’s population is under nourished, need for such right food combination increases manifolds. Owing to per 100g nutritive value of these contents and their cost effectiveness, this combination has a potential to be a perfect staple dietary option for nutrition deficit individuals. It needs to be further established at large scale through RCTs so that large population can be benefitted

    Thermodynamic Properties of Ni-substituted LnCoO3 Perovskite

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    With the objective of exploring the unknown thermodynamic properties of Ni-substituted LnCoO3 perovskite, we present here an investigation of the temperature-dependent (10K < T < 300K) specific heat of LnCo0.95Ni0.05O3 (Ln=Pr and Nd) family. We report here probably for the first time the specific heat along with other elastic and thermal properties of Ni doped perovskite cobaltate LnCoO3 (Ln=Pr and Nd). In addition, the results on the cohesive energy (f) in orthorhombic perovskite phase, molecular force constant (Ć’), Reststrahlen frequency (uo) and Gruneisen parameter (Îł) are also presented. Keywords: Specific heat, Bulk modulus, Perovskite cobaltat

    Influence of hospital policy on partograph use in tertiary care facilities in India: a cross sectional survey

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    Background: Partograph is an effective, but underutilized tool for monitoring labour. This study examined the influence of hospital policy on the knowledge, attitude, practice and skills of doctors towards partograph plotting.Methods: A cross-sectional survey among doctors posted in labour rooms of tertiary care public teaching hospitals of India was carried out, using self-administered questionnaire to assess knowledge, attitude and practice; and labour case scenarios were provided to assess partograph plotting skills. Chi-square test or Fisher’s exact test were employed to test the significance of association between knowledge, attitude, practice and skills of 150 doctors working in hospitals with (n=3) and without (n=2) policy of routine partograph plotting.Results: The majority of doctors in both groups had correct knowledge about different partograph components. However, doctors working in hospitals with a policy of partograph use, demonstrated significantly better skills using case scenarios for plotting partographs (p<0.01), and a positive attitude towards plotting partograph and its use as a decision support tool (p=0.000) as compared to doctors working in hospitals without a routine partograph plotting policy.Conclusions: Hospital policy of routine partograph plotting may positively influence utilization of partograph in tertiary care public hospitals in India

    Phytochemical investigations, in-vitro antioxidant, antimicrobial potential, and in-silico computational docking analysis of Euphorbia milii Des Moul

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    Euphorbia milii Des Moul is a deciduous bush indigenous to Madagascar. The present study aims to investigate the presence of the phytochemical, in-vitro antioxidant and antimicrobial potency, and in-silico computational analysis of ethanolic and aqueous preparations of E. milii leaves and flowers. The ethanolic and aqueous extracts were tested for in-vitro antioxidant activity by DPPH, H2O2, TAC, and FRAP assay. In addition, antimicrobial potentials were assayed by agar well diffusion technique against Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, and Candida albicans for various clinical isolates. The qualitative phytochemical analysis results confirmed the existence of alkaloids, flavonoids, phenolics, and tannins. The quantitative analysis elicits the availability of a magnificent number of alkaloids, flavonoids, phenolics, flavonols, and tannins. Among all the extracts, aqueous extracts of leaves exhibited potent antioxidant activity in DPPH, FRAP, and H2O2 assay with the IC50 value of 30.70, 60.05, and 82.92µg/mL, respectively. In agar well diffusion assay, all extracts displayed zone of inhibition varies from 2-24mm at different concentrations ranging from 10-320 mg/mL, whereas no activity was observed against Candida albicans. Furthermore, docking-based computational analysis has revealed that beta-sitosterol and taraxerol are the plant's active constituents responsible for their antimicrobial and antioxidant activities. Research findings suggest that the E. milii plant has an excellent prospect for further study for its extended antioxidative and antimicrobial potential. It could be a natural source of various ailments and can be utilized to develop new drugs

    A cluster randomized, controlled trial of breast and cervix cancer screening in Mumbai, India: methodology and interim results after three rounds of screening

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    Cervix and Breast cancers are the most common cancers among women worldwide and extract a large toll in developing countries. In May 1998, supported by a grant from the NCI (US), the Tata Memorial Hospital, Mumbai, India, started a cluster-randomized, controlled, screening-trial for cervix and breast cancer using trained primary health workers to provide health-education, visual-inspection of cervix (with 4% acetic acid-VIA) and clinical breast examination (CBE) in the screening arm, and only health education in the control arm. Four rounds of screening at 2-year intervals will be followed by 8 years of monitoring for incidence and mortality from cervix and breast cancers. The methodology and interim results after three rounds of screening are presented here. Good randomization was achieved between the screening (n = 75360) and control arms (n = 76178). In the screening arm we see: High screening participation rates; Low attrition; Good compliance to diagnostic confirmation; Significant downstaging; Excellent treatment completion rate; Improving case fatality ratios. The ever-screened and never-screened participants in the screening arm show significant differences with reference to the variables religion, language, age, education, occupation, income and health-seeking behavior for gynecological and breast-related complaints. During the same period, in the control arm we see excellent participation rate for health education; Low attrition and a good number of symptomatic referrals for both cervix and breast

    Plasmodium vivax lineages: geographical distribution, tandem repeat polymorphism, and phylogenetic relationship

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    <p>Abstract</p> <p>Background</p> <p>Multi-drug resistance and severe/complicated cases are the emerging phenotypes of vivax malaria, which may deteriorate current anti-malarial control measures. The emergence of these phenotypes could be associated with either of the two <it>Plasmodium vivax </it>lineages. The two lineages had been categorized as Old World and New World, based on geographical sub-division and genetic and phenotypical markers. This study revisited the lineage hypothesis of <it>P. vivax </it>by typing the distribution of lineages among global isolates and evaluated their genetic relatedness using a panel of new mini-satellite markers.</p> <p>Methods</p> <p><it>18S SSU rRNA S-type </it>gene was amplified from 420 <it>Plasmodium vivax </it>field isolates collected from different geographical regions of India, Thailand and Colombia as well as four strains each of <it>P. vivax </it>originating from Nicaragua, Panama, Thailand (Pak Chang), and Vietnam (ONG). A mini-satellite marker panel was then developed to understand the population genetic parameters and tested on a sample subset of both lineages.</p> <p>Results</p> <p><it>18S SSU rRNA S-type </it>gene typing revealed the distribution of both lineages (Old World and New World) in all geographical regions. However, distribution of <it>Plasmodium vivax </it>lineages was highly variable in every geographical region. The lack of geographical sub-division between lineages suggests that both lineages are globally distributed. Ten mini-satellites were scanned from the <it>P. vivax </it>genome sequence; these tandem repeats were located in eight of the chromosomes. Mini-satellites revealed substantial allelic diversity (7-21, <it>AE </it>= 14.6 ± 2.0) and heterozygosity (<it>He </it>= 0.697-0.924, <it>AE </it>= 0.857 ± 0.033) per locus. Mini-satellite comparison between the two lineages revealed high but similar pattern of genetic diversity, allele frequency, and high degree of allele sharing. A Neighbour-Joining phylogenetic tree derived from genetic distance data obtained from ten mini-satellites also placed both lineages together in every cluster.</p> <p>Conclusions</p> <p>The global lineage distribution, lack of genetic distance, similar pattern of genetic diversity, and allele sharing strongly suggested that both lineages are a single species and thus new emerging phenotypes associated with vivax malaria could not be clearly classified as belonging to a particular lineage on basis of their geographical origin.</p

    Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

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    Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

    Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV