272 research outputs found

    Performance analysis of coconut enterprises facilitated through agribusiness incubators

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    Agribusiness incubators (ABI) catalyze entrepreneurship development by facilitating technology and institutionalized services. The study addresses the performance analysis of enterprises promoted through coconut sector ABIs working in Kerala. Primary and secondary data collected from 30 randomly selected ABI graduated entrepreneurs in business were used to characterize the enterprises. The results indicated that 56 per cent of enterprises joined ABIs at the nascent stage and were able to receive government funding under different subsidy schemes. Majority of enterprises (72%) shared features of micro-enterprises in terms of the number of persons employed (01-10) and annual turnover less than ` 25 lakh. Most of the micro-enterprises (66%) functioned as sole proprietary firms, whereas small enterprises were registered as limited company/partnership firms (20%). Virgin coconut oil (VCO) was the major product in 40 per cent of enterprises followed by coconut chips (20%), coconut chocolates (10%), desiccated coconut (07), neera and tender coconut water-based drinks (07%). Performances of two purposively selected enterprises producing VCO and coconut chips were undertaken using break-even analysis. Production and sales of both VCO and coconut chips were more than the calculated BEP values of 1000 litres and 500 kg respectively. This indicated that both enterprises operated at profitable levels. The findings suggest that the entrepreneurs who completed the business incubation program had greater success in their business irrespective of the business size. This can be attributed to their greater access to technologies and entrepreneurship development programmes under the ABI

    PRE-MARITAL SCREENING TESTS OF β-THALASSEMIA TRAIT IN DAKSHINA KANNADA POPULATION OF KARNATAKA

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    Objective: β-Thalassemia is one of the familiar single gene disorders which passes from parents to offspring. The prevalence of β-thalassemia trait varies from 1-14% in different regions of India. Every year almost 9000 β-thalassemic major children are being born in the Indian sub-continent. In the present study, the prevalence of β-thalassemia trait was checked and some screening tests were performed to detect it among the Dakshina Kannada population of Karnataka.Methods: A total of 800 youngsters were selected for the study, males being above 21 y and females above 18 y. Two ml of blood was drawn and collected in K2 EDTA bottles and complete hemogram was immediately checked. Samples which have Mean Corpuscular Volume (MCV)<80 fico litres(fl) were selected for the study. Five discriminant functions were calculated. NESTROFT (Naked Eye Single Tube Red Cell Osmotic Fragility Test) was performed in all the samples. The samples which show positive for NESTROFT and at least 2 discriminant functions were further checked for HbA2 level using cellulose acetate electrophoresis to confirm the β-thalassemia trait. A comparison was made with the normal samples which have MCV ˃ 80fl.Results: Prevalence of β-thalassemia trait was found to be 5.125 % in this population. The obtained values were analyzed using unpaired Student's‘t' test using GraphPad prism (Version-3.0). Samples of β-thalassemia trait have significant changes in the white blood corpuscles (WBC p=0.1266), red blood corpuscles (RBC p=0.0130), hemoglobin (Hb p<0.0001), hematocrit (HCT p<0.0001), MCV(p<0.0001), mean corpuscular hemoglobin (MCH p<0.0001), mean corpuscular hemoglobin concentration (MCHC p<0.0001), platelets (PLT p=0.0005), HbA2(p<0.0001) compared to normal controls.Conclusion: The present study shows that the people with β-thalassemia trait have a significant variation in complete hemogram compared to normal; NESTROFT and discriminant functions can be used for the screening of β-thalassemia trait in the population

    Spring inter monsoon algal blooms in the Eastern Arabian sea: Shallow marine encounter off Karwar and Kumbla Coast using a Hyperspectral radiometer

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    We encountered the presence of algal blooms in the shallow coastal waters; typical of case II conditions off Karwar (Karnataka) and Kumbla (Kerala), eastern Arabian Sea during the Inter Monsoon. The algal blooms are Trichodesmium species and appear in shades of brown strands and tufts representing T. Erythraeum. Sites of the algal blooms depict a high spectrophotometric surface chlorophyll-a value ranging from 32- 39 mgm-3 and sea surface area surrounding the bloom sites depict lower values of chlorophyll-a (1-3 mgm-3). In-situ Hyperspectral radiometer measurements depict the existence of Chlorophyll Maxima at various depths (3.0-37.31 ug/l) representing the blooms along with their surface appearance. Contrary to the Karwar blooms that are dense, the blooms at Kumbla were dispersed and scantly distributed on the surface waters. Our sea-truth data on mean Sea Surface Temperature of Karwar (30.61 °C) that simulates the Kumbla (30.34 °C) scenario and the mean salinity of Kumbla was 35.86psu, and that of Karwar that is slightly elevated (35.40psu), suggests that SST and salinity probably do not either directly enhance or provide an environment for the eterioration of algal blooms

    An Experimental Study on Utilization of Iron Ore Tailings (IOT) and Waste Glass Powder in Concrete

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    Cement manufacturing industry is one of the carbon dioxide emitting sources besides deforestation burning of fossil fuels. The global warming is caused by the emission of green house gases, such as CO2, to the atmosphere. Among the greenhouse gases, CO2 contributes about 65% of global warming. The global cement industry contributes about 7% of green house gas emission to the earth’s atmosphere. In order to address environmental effects associated with cement manufacturing, there is a need to develop alternative binders to make concrete. Consequently extensive research is on going into the use of cement replacements, using many waste materials industrial by products. Efforts have been made in the concrete industry to use waste glass as partial replacement of cement and also in recent years almost every mineral producing country is facing the problem of better utilization of mine waste because of its accumulation lack of suitable storage space. In this study, finely powdered waste glass from industries and Iron Ore Tailings (IOT) produced from mining areas are used as a partial replacement  of cement and fine aggregates in concrete respectively.  This work examines the possibility of using Glass powder and iron ore tailing as a partial replacement of cement and fine aggregate in concrete. In the present study  Glass powder and Iron Ore Tailing  ( IOT )  are partially replaced by 10%, 20%, 30% and  40%  tested for its compressive, flexural strength for 7, 28 and 56 days of curing and were compared with those of conventional concrete. Keywords: Glass Powder – GP, Iron Ore Tailings – IOT, Conventional Concrete - C

    Beta-blockers and glioma: a systematic review of preclinical studies and clinical results

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    Given the median survival of 15 months after diagnosis, novel treatment strategies are needed for glioblastoma. Beta-blockers have been demonstrated to inhibit angiogenesis and tumor cell proliferation in various cancer types. The aim of this study was to systematically review the evidence on the effect of beta-blockers on glioma growth. A systematic literature search was performed in the PubMed, Embase, Google Scholar, Web of Science, and Cochrane Central to identify all relevant studies. Preclinical studies concerning the pharmacodynamic effects of beta-blockers on glioma growth and proliferation were included, as well as clinical studies that studied the effect of beta-blockers on patient outcomes according to PRISMA guidelines. Among the 980 citations, 10 preclinical studies and 1 clinical study were included after title/abstract and full-text screening. The following potential mechanisms were identified: reduction of glioma cell proliferation (n = 9), decrease of glioma cell migration (n = 2), increase of drug sensitivity (n = 1), induction of glioma cell death (n = 1). Beta-blockers affect glioma proliferation by inducing a brief reduction of cAMP and a temporary cell cycle arrest in vitro. Contrasting results were observed concerning glioma cell migration. The identified clinical study did not find an association between beta-blockers and survival in glioma patients. Although preclinical studies provide scarce evidence for the use of beta-blockers in glioma, they identified potential pathways for targeting glioma. Future studies are needed to clarify the effect of beta-blockers on clinical endpoints including survival outcomes in glioma patients to scrutinize the value of beta-blockers in glioma care

    Heterogeneous microbial oceanographic environments: Application of GIS technology in deciphering of microenvironment scenarios off the central west coast of India

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    In the vast oceanic microbial environment of 2468.83km 2, GIS modeling techniques involving sixty query steps, enabled the deciphering of Microenvironments as low as 1.19km 2 to 38.6 km 2 for the summer of 2004 and in case of summer 2005 where 84 query steps were involved to decipher Microenvironments of 10.55km 2 to 25.94km 2. Thirtythree sampling stations were established between Betul to Ankola off the central west coast of India accounting for a spatial coverage of 2468.83km 2. GIS query-modeling investigation was carried out using spatial layers of depth, optical parameters (k-Irradiance attenuation Coefficient, c-Beam attenuation coefficient), sediment size parameters (Sediment Mean Size and Sediment Sorting) and Benthic Foraminifera Suborders (Rotaliina, Textulariina, Miliolina, Lagenina). Foraminifera have been used as a surrogate parameter. However, any microbial parameter could proxy for foraminifers providing for the numerical deciphering of microenvironments. This is suggestive of the assimilation of GIS technology for a better appreciation of microbial oceanography

    Sinapis arvensis-Wild Mustard as an Anti-inflammatory Agent: An In-vitro Study

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    Introduction: Inflammation is body’s immune response to harmful stimulus. Commonly used conventional anti-inflammatory agents are Non-Steroidal Anti-inflammatory Drugs (NSAIDs). But on prolonged long-term use, it causes serious adverse events. So, the search towards natural agents which have anti-inflammatory property are increasing nowadays. Sinapis arvensis is an annual flowering plant which has proven multipurpose medicinal phytoconstituents. Aim: To evaluate in-vitro anti-inflammatory effects of flower extracts of Sinapis arvensis with diclofenac as standard. Materials and Methods: This in-vitro study assessed the laboratory based anti-inflammatory activity, performed using Bovine Serum Albumin (BSA) assay in December 2021 at Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India. BSA at pH of 6.8 generated denatured proteins. The anti-inflammatory activity of the sample (flower extracts of Sinapis arvensis) and standard (Diclofenac) was assessed by adding to BSA and percentage of inhibition of denaturation were calculated using the formula based on the absorbance measured. Descriptive statistics was used for analysis of collected data. Results: The concentration-dependent inhibition of protein denaturation was observed for both Sinapis arvensis and Diclofenac. At 100 μg concentration, percentage of inhibition reached up to 81.8% and 100% for Sinapis arvensis and Diclofenac, respectively. Conclusion: The present study showed that flower extracts of Sinapis arvensis exhibited concentration dependent anti-inflammatory property invitro which proves to be nearly equivalent with that of the standard Diclofenac
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