261,220 research outputs found

    Emergency space-suit helmet

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    A frusto-conically shaped distensible component is described which inflates to encircle a portion of the wearer's head and carries a collapsible member which automatically extends over the remaining portion of the head. A pulley arrangement secured between the walls of the distensible component automatically extends and retracts the collapsible member. When deflated, the unit is carried on the back of the wearer so as to provide an automatic emergency space suit helmet

    Spherical tank gauge Patent

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    Gauge for measuring quantity of liquid in spherical tank in reduced gravit

    Regulation of the \u3cem\u3eEscherichia coli\u3c/em\u3e Tryptophan Operon by Early Reactions in the Aromatic Pathway

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    7-Methyltryptophan (7MT) or compounds which can be metabolized to 7MT, 3-methylanthranilic acid (3MA) and 7-methylindole, cause derepression of the trp operon through feedback inhibition of anthranilate synthetase. Tyrosine reverses 3MA or 7-methylindole derepression, apparently by increasing the amount of chorismic acid available to the tryptophan pathway. A mutant isolated on the basis of 3MA resistance (MAR 13) was found to excrete small amounts of chorismic acid and to have a feedback-resistant phenylalanine 3-deoxy-d-arabinoheptulosonic acid-7-phosphate (DAHP) synthetase. Genetic evidence indicates that the mutation conferring 3MA resistance and feedback resistance is very closely linked to aroG, the structural gene for the DAHP synthetase (phe). Since feedback inhibition of anthranilate synthetase by l-tryptophan (or 7MT) is competitive with chorismic acid, alterations in growth conditions (added tyrosine) or in a mutant (MAR 13) which increase the amount of chorismic acid available to the tryptophan pathway result in resistance to 7MT derepression. Owing to this competitive nature of tryptophan feedback inhibition of anthranilate synthetase by chorismic acid, the early pathway apparently serves to exert a regulatory influence on tryptophan biosynthesis

    Review of spectroscopic parameters for upper atmospheric measurements

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    The workshop included communication of spectroscopic data requirements for the planned upper atmosphere research satellite (UARS) mission, review of the status of currently available spectroscopic parameters, and recommendation of additional studies. The objectives were accomplished and resulted in a series of general and specific recommendations for laboratory spectroscopy research to meet the needs of UARS and other atmospheric remote sensing programs

    Mechanism of 3-Methylanthranilic Acid Derepression of the Tryptophan Operon in \u3cem\u3eEscherichia coli\u3c/em\u3e

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    3-Methylanthranilic acid (3MA) inhibits growth and causes derepression of the tryptophan biosynthetic enzymes in wild-type strains of Escherichia coli. Previous reports attributed this effect to an inhibition of the conversion of 1-(o-carboxyphenylamino)-1-deoxyribulose 5-phosphate to indole-3-glycerol phosphate and a consequent reduction in the concentration of endogenous tryptophan. Our studies have shown that 3MA-resistant mutants linked to the tryptophan operon have a feedback-resistant anthranilate synthetase; mutants with an altered indole-3-glycerol phosphate synthetase were not found. 3MA or 7-methylindole can be metabolized to 7-methyltryptophan, and 3MA, 7-methylindole, and 7-methyltryptophan lead to derepression of the tryptophan operon. Furthermore, 3MA-resistant mutants are also resistant to 7-methylindole derepression. These results strongly suggest that the primary cause of derepression by 3MA is through its conversion to 7-methyltryptophan, which can inhibit anthranilate synthetase, thereby decreasing the concentration of endogenous tryptophan. Unlike 5- or 6-methyltryptophan, 7-methyltryptophan does not appear to function as an active corepressor

    Nongrey radiation effects on the boundary layer of an absorbing gas over a flat plate

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    Nongrey radiation effects on boundary layer of absorbing gas over flat plat

    Characterization of vibrational overtones and "local" modes by emission spectroscopy

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    Cereal Leaf Beetle (Coleoptera: Chrysomelidae) Influence of Seeding Rate of Oats on Populations

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    In field and greenhouse studies, more cereal leaf beetle [Oulema melanopus (Lin- naeus)] eggs and larvae were found per unit area on spring oats, Avena sativa L., planted either at intermediate (54 kg/ha) or high (136 kg/ha) seeding rates, than when planted at a lower seeding rate (14 kg/ha). However, there were fewer eggs and larvae per stem in plantings of the high or intermediate rates than in those of the lower rate. Oats should not be planted at less than the recommended rates in beetle-infested areas
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