208 research outputs found

    CBCSS, An Innovation In University Education: A Study From The Perspective Of College Teachers Of Mahatma Gandhi University In Kerala

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    Indian higher education system is both enormous and complex. It has unleashed a major program of reforms. In purview with such reforms University Grants Commission (UGC) has made many changes with regard to the higher education system. CBCSS or ‘Choice based Credit Semester and grading pattern ‘was a prominent reform. Mahatma Gandhi regulations are framed in accordance with UGC guidelines. The purpose of this study was to better understand the innovations in University education and CBCSS from the perspective of teachers of colleges falling under MG University

    Stromal Expression of CD10 in Invasive Breast Carcinoma and Its Correlation with ER, PR, HER2-neu, and Ki67

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    CD10 is a cell surface zinc-dependent endopeptidase, which degrades many bioactive peptides. CD10 expression in tumour stroma is associated with biological aggressiveness of many epithelial malignancies. To date, only one study has correlated with expression of CD10 with well-known prognostic markers of breast, that is, ER, PR, HER2-neu, and tumour grade; however, its correlation with ki67 is still not studied. The aim of this study is to evaluate stromal CD10 expression in breast carcinoma and to examine its correlation with ER, PR, HER2-neu, and Ki67. Methods and Results. CD10 expression in fifty patients was assessed by immunohistochemistry and scored as negative, weak and strong. CD10 was found to be positive in stroma of 40/50 (80%) cases. Stromal CD10 showed positive correlation with tumour grade, HER2-neu (P = .000), and ki67 (P = .027), negative correlation with ER and PR. Conclusions. Hence CD10 expression correlated strongly with well-established negative prognostic markers, that is, HER2-neu and ki67 positivity, ER/PR negativity, and higher tumour grade, thus indicating that CD10 can be used as independent marker indicating poor prognosis and can be used as target for the development of novel therapies

    One qubit almost completely reveals the dynamics of two

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    From the time dependence of states of one of them, the dynamics of two interacting qubits is determined to be one of two possibilities that differ only by a change of signs of parameters in the Hamiltonian. The only exception is a simple particular case where several parameters in the Hamiltonian are zero and one of the remaining nonzero parameters has no effect on the time dependence of states of the one qubit. The mean values that describe the initial state of the other qubit and of the correlations between the two qubits also are generally determined to within a change of signs by the time dependence of states of the one qubit, but with many more exceptions. An example demonstrates all the results. Feedback in the equations of motion that allows time dependence in a subsystem to determine the dynamics of the larger system can occur in both classical and quantum mechanics. The role of quantum mechanics here is just to identify qubits as the simplest objects to consider and specify the form that equations of motion for two interacting qubits can take.Comment: 6 pages with new and updated materia

    Case report on splenic abscess with pleural effusion caused by enteric fever

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    Splenic abscess is an infrequent complication of enteric fever caused by Salmonella typhi. The incidence rate ranges from 0.14-2%. Clinical manifestations are often nonspecific and may be presented as fever with left upper quadrant abdominal pain and a palpable tender mass. Diagnosis is often difficult and splenic abscess management is based on surgical interventions and antibiotic therapy. In this case report we would like to highlight splenic abscess with left reactive pleural effusion as a rare complication of Salmonella typhi infection

    Lorentz transformations that entangle spins and entangle momenta

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    Simple examples are presented of Lorentz transformations that entangle the spins and momenta of two particles with positive mass and spin 1/2. They apply to indistinguishable particles, produce maximal entanglement from finite Lorentz transformations of states for finite momenta, and describe entanglement of spins produced together with entanglement of momenta. From the entanglements considered, no sum of entanglements is found to be unchanged.Comment: 5 Pages, 2 Figures, One new paragraph and reference adde

    Laparoscopic Treatment of Gastric Bezoar

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    Detailed in this report is the laparoscopic removal of a gastric bezoar through an anterior wall gastrotomy

    Evaluation of Sentinel Node Biopsy in Locally Advanced Breast Cancer Patients Who Become Clinically Node-Negative after Neoadjuvant Chemotherapy: A Preliminary Study

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    Introduction. Controversy continues over the appropriate timing of sentinel lymph node (SLN) biopsy in locally advanced breast cancer (LABC) patients receiving neoadjuvant chemotherapy. We evaluated the feasibility and accuracy of SLN biopsy in LABC patients with cytology-proven axillary nodal metastasis who become clinically node-negative after neoadjuvant chemotherapy. Materials. 30 consecutive patients with LABC, who had become clinically node-negative after 3 cycles of neoadjuvant chemotherapy, were included in the study. They were then subjected to SLN biopsy, axillary lymph node dissection, and breast surgery. Results. Sentinel nodes were successfully identified in 26 of the 30 patients, resulting in an identification rate of 86.67%, sensitivity of 83.33%, false negative rate of 20%, negative predictive value of 72.73%, and an overall accuracy of 88.46%. No complications were observed as a result of dye injection. Conclusions. SLN biopsy is feasible and safe in LABC patients with cytology-positive nodes who become clinically node-negative after neoadjuvant chemotherapy. Our accuracy rate, identification rate, and false negative rate are comparable to those in node-negative LABC patients. SLN biopsy as a therapeutic option in LABC after neoadjuvant chemotherapy is a promising option which should be further investigated

    Corrosion analysis and performance investigation of hybrid MXene/C-dot Nanofluid-Based direct absorption solar collector

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    Nanofluids having exceptional thermo-optical characteristics can enhance the performance of direct absorption solar collectors (DASC). Conventional nanofluids have either high optical properties or thermal properties. In this study, carbon quantum dot (C-dot) nanomaterial with high stability and optical absorption along the UV range, and MXene nanoparticles with high thermal conductivity and absorption along visible and near-infrared (NIR) spectral range was selected for synthesizing a hybrid nanomaterial with synergistic thermo-optical properties. Hybrid MXene/C-dot nanofluid exhibits higher stability, thermal conductivity, and complementary absorption properties of individual nanomaterials. A two-step method was used for the synthesis of nanofluids using water as the base fluid. Thermal conductivity, UV–Vis-NIR spectroscopy, and stability analysis were conducted on nanofluids, and the concentration was optimized for corrosion study and application in direct absorption parabolic trough collector (DAPTC). Optimised concentrations of C-dot, MXene, and hybrid nanofluids were 0.15 wt%, 0.1 wt% and 0.15 wt%, respectively. The corrosion study states that copper electrodes dipped in the hybrid nanofluid exhibited the least corrosion rate of 0.6 mm/year with an anticorrosion efficiency of 64.5 % over DI water. Thermal efficiency and entropy generation in the system with different HTFs were measured and compared with that of the base fluid. The study shows that C-dot and MXene/C-dot nanofluids were producing the highest efficiencies of 50.5 % and 47.5 % at a flow rate of 1.2 lpm. This study shows that hybrid MXene/C-dot nanofluid exhibited exceptional thermal stability, reduced corrosion effects, and considerable enhancement in photothermal conversion efficiency of the DASC

    Prevalence of oral soft tissue lesions in Vidisha

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    <p>Abstract</p> <p>Background</p> <p>The purpose of this study was to determine the prevalence of oral soft tissue lesions in patients and to assess their clinicopathological attributes. 3030 subjects belonging to a semi-urban district of Vidisha in Central India were screened. Patients were examined with an overhead examination light and those who were identified with a questionable lesion underwent further investigations. Statistical analysis was done using the SPSS software.</p> <p>Findings</p> <p>8.4 percent of the population studied had one or more oral lesions, associated with prosthetic use, trauma and tobacco consumption. With reference to the habit of tobacco use, 635(21%) were smokers, 1272(42%) tobacco chewers, 341(11%) smokers and chewers, while 1464(48%) neither smoked nor chewed. 256 patients were found to have significant mucosal lesions. Of these, 216 cases agreed to undergo scalpel biopsy confirmation. 88 had leukoplakia, 21 had oral submucous fibrosis, 9 showed smoker's melanosis, 6 patients had lichen planus, 17 had dysplasia, 2 patients had squamous cell carcinoma while there was 1 patient each with lichenoid reaction, angina bullosa hemorrhagica, allergic stomatitis and nutritional stomatitis.</p> <p>Conclusions</p> <p>The findings in this population reveal a high prevalence of oral soft tissue lesions and a rampant misuse of variety of addictive substances in the community. Close follow up and systematic evaluation is required in this population. There is an urgent need for awareness programs involving the community health workers, dentists and allied medical professionals.</p
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