6 research outputs found

    Congenital hypothyroidism presenting as isolated macroglossia in a term neonate: A case report

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    Macroglossia is a clinical condition in which the tongue protrudes beyond the teeth or alveolar ridge during resting posture, or there is an impression of a tooth on the lingual border with the mouth open. True macroglossia occurs in hypothyroidism, Beckwith–Wiedemann syndrome, and storage disorders. Apparent or pseudo macroglossia may result from neurological impairment of the tongue or a relatively small buccal cavity as in Pierre Robin syndrome and Down’s syndrome. Rarely, macroglossia is inherited as an autosomal dominant condition. A wide variety of primary conditions of the tongue can cause tongue enlargement, e.g., lingual thyroid, cysts, tumors, hemangioma, lymphatic malformations, and myositis. Symptoms associated with macroglossia include noisy breathing, stridor, snoring, and feeding difficulties. Although macroglossia is described in hypothyroidism, there are few publications on macroglossia presenting in the neonatal period. We report a case of congenital hypothyroidism presenting as isolated macroglossia at birth in a term neonate

    Achromobacter xylosoxidans Causing Late-onset Sepsis with Pneumonia in a Term Neonate

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    Achromobacter xylosoxidans (A. xylosoxidans), is an aerobic gram negative motile bacillus that rarely causes infection in healthy adults and is exceptionally rare in neonates. A. xylosoxidans is ubiquitous in nature, causing nosocomial infections especially in debilitated and immunocompromised patients. Few outbreaks caused by this organism were reported in Neonatal Intensive Care Units (NICU) along with sporadic cases in neonates. A 3-week-old term neonate presented with late-onset sepsis and pneumonia caused by A. xylosoxidans that was successfully treated with antibiotics and supportive care. Awareness regarding this uncommon pathogen and initiation of appropriate antibiotic therapy would improve the outcome and prevent mortalit

    Organophosphorus Poisoning with Homicidal Intention in a Neonate

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    Organophosphorus Compounds (OPC) are widely used as pesticides, and poisoning due to OPC is very rare in neonates. A 12-dayold female neonate was admitted with gasping respiration, excessive oral secretions and cold extremities. She had frothing from mouth and nose with an offensive odour, was hypothermic, hypotonic, cyanosed and was in mild stupor. Pupils were pin pointed, capillary refill time was 4-5 sec and had bilateral crepitations of lungs on auscultation. The baby was intubated, given 0.1 mg of atropine followed by 0.9% saline bolus and gastric lavage. She was treated with empirical antibiotics, atropine, Pralidoxime (PAM) and respiratory support. The baby responded well to treatment and was discharged on 10th day of admission. This could be the second case of Organophosphorus (OP) poisoning with homicidal intention reported in neonates

    Campomelic dysplasia with 10 pairs of ribs in a preterm neonate: A case report

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    Campomelic dysplasia (CD) is a rare form of skeletal dysplasia (incidence 1:200,000 births) which is associated with characteristic phenotypes including bowing of the limbs, a narrow thoracic cage, 11 pairs of ribs, hypoplastic scapulae, macrocephaly, flattened supraorbital ridges and nasal bridge, cleft palate, and micrognathia. In addition to the skeletal abnormalities, hydrocephalus, hydronephrosis, and congenital heart disease have been reported. We describe a preterm neonate who presented with respiratory failure and clinical features of CD. Our case had only 10 pairs of ribs, and to the best of our knowledge this is the first case report of CD with 10 pairs of ribs

    Congenital diaphragmatic hernia, Meckel′s diverticulum and malrotation in a 3-month-old infant

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    Congenital diaphragmatic hernia (CDH) is a common developmental anomaly that usually presents in the neonatal period. It is known to be associated with cardiac, renal, genital and chromosomal anomalies. Late presentation of CDH (beyond 1-month of age) is seen in 13% of the cases. Malrotation is reported in 42% of CDH cases. We report a case of a 3-month-old infant with concurrent CDH, Meckel′s diverticulum and malrotation. This is the first case report of such an association in an infant