2,866 research outputs found

    Nonlinear aeroelastic modeling via conformal mapping and vortex method for a flat-plate airfoil in arbitrary motion

    Get PDF
    A nonlinear aerodynamic modeling based on conformal mapping is presented to obtain semi-analytical formulas for the unsteady aerodynamic force and pitching moment on a flat-plate airfoil in arbitrary motion. The aerodynamic model accounts for large amplitudes and non-planar wake and is used to study the aeroelastic behavior of a flat-plate airfoil elastically connected to a support. The fluid is assumed to be inviscid and incompressible, while the flow is assumed to be attached, planar, and potential. Within these hypotheses, conformal mapping and a complex-potential representation of unsteady aerodynamics are used to simplify the theoretical formulation. The vorticity shed at the trailing edge is discretized in desingularized point vortices in order to allow free-wake dynamics. The unsteady aerodynamic model is validated with classical linearized formulations based on the assumption of small disturbances, and with experimental data and theoretical predictions for a large-amplitude pitch-up, hold, pitch-down maneuver. The aeroelastic model is then used to simulate the response of a flat-plate airfoil to sudden starts and body-vortex interactions. Numerical results show that the proposed approach can be an effective tool to model the aeroelastic behavior of an arbitrarily-moving wing section in a time-dependent potential stream of incompressible fluid

    Study of high-pT charged particle suppression in PbPb compared to pp collisions at sqrt(sNN)=2.76 TeV.

    Get PDF
    The transverse momentum spectra of charged particles have been measured in pp and PbPb collisions at sqrt(sNN) = 2.76 TeV by the CMS experiment at the LHC. In the transverse momentum range pt = 5-10 GeV/c, the charged particle yield in the most central PbPb collisions is suppressed by up to a factor of 5 compared to the pp yield scaled by the number of incoherent nucleon-nucleon collisions. At higher pt, this suppression is significantly reduced, approaching roughly a factor of 2 for particles with pt in the range pt=40-100 GeV/c

    Effect of an Anhydride Excess on the Curing Kinetics and Dynamic Mechanical Properties of Synthetic and Biogenic Epoxy Resins

    Get PDF
    This work analyzes the effect of the anhydride excess on the nonisothermal curing kinetics and on the final properties of synthetic and biobased epoxy resins. Diglycidyl ether of bisphenol A (DGEBA) and epoxidized soybean oil (ESO) were crosslinked using methyltetrahydrophthalic anhydride (MTHPA) as a curing agent and 1-methylimidazole (1MI) as an initiator. It was shown that the ESO/MTHPA/1MI system reacts slower than the DGEBA/MTHPA/1MI system, giving place to a more significant evaporation of the curing agent during the reaction. As a result, an excess of anhydride improves the final thermal properties of the ESO/MTHPA/1MI network, contrary to the behavior observed for DGEBA/MTHPA/1MI. The knowledge of the kinetics of the curing process and the optimal amount of the curing agent for each system is of critical importance for a more efficient processing of these materials.Fil: Altuna, Facundo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Riccardi, Carmen Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Marin Quintero, Diana Catalina. Royal Institute of Technology; Suecia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Ruseckaite, Roxana Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Stefani, Pablo Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentin

    EFEITO DO JEJUM P√ďS-ECLOS√ÉO SOBRE PINTOS DE CORTE PROVENIENTES DE OVOS LEVES E PESADOS

    Get PDF
    Este estudo analisou o efeito do jejum p√≥s-eclos√£o sobre o peso corporal e pesos do f√≠gado, cora√ß√£o e saco de vitelo de pintos provenientes de ovos leves de matrizes jovens (29 semanas) e de ovos pesados de matrizes velhas (60 semanas). Foi analisado o efeito de tr√™s regimes alimentares (alimenta√ß√£o com √°gua e ra√ß√£o, jejum de √°gua e ra√ß√£o e jejum de ra√ß√£o), da dura√ß√£o do jejum (24, 48 e 72 horas), e de dois pesos de ovos (leves ou pesados), e as suas intera√ß√Ķes. O jejum afetou os pesos corporal e ¬†dos √≥rg√£os. Pintos de ovos pesados perderam mais peso e absorveram mais o saco de vitelo que os pintos de ovos leves. O efeito do jejum ¬†sobre ¬†os pesos corporal e do ¬†f√≠gado ocorreu com 24 horas, ¬†e sobre o peso do cora√ß√£o ¬†com 72 horas. PALAVRAS-CHAVES: Idade da matriz, jejum, √≥rg√£os, peso corporal.

    Hettangian and Sinemurian (Lower Jurassic) biostratigraphy of Argentina

    Get PDF
    On the northern bank of the Rio Atuel, Mendeza province, Argentina, the marine fossilfferous Mesozoic is now known to begin with Hettangian-lower Sinemurian strata. Traditionally, the marine Jurassic sequence in the area was believed to start with upper Sinemurian levels. Representatives of the genera Psiloceras Hyatt, Caloceras Hyatt, Alsatites Haug, Waehneroceras Hyatt, Schlotheimia Bayle, Sulciferites Spath, Badouxia Guex and Taylor, Vermiceras Hyatt, Coroniceras Hyatt, Agassiceras Hyatt, Euagassiceras Spath, and Arnioceras Hyatt thus indicate the presence of beds equivalent to the Planorbis, Liasieus, Angulata, Bucklandi, Semicostatum, and Turneri zones of the standard international chronostratigraphic scale. Hence, in Argentina, the marine Hettangian, Sinemurian, and lowermost Pliensbachian have been proved only in the neighborhood of the Rio Atuel region, where marine Triassic could also be represented. Elsewhere in Argentina, the oldest Jurassic ammonite-bearing levels usually belong to the upper lower or the upper Pliensbachian. Regionally, these findings imply a substantial modification to previous paleogeographic reconstructions for the Early Jurassic of South America.En la margen norte del rio Atuel, Mendoza, Argentina, la sucesi6n fosilifera marina del Mesozoieo comienza con niveles del Hettangiano y Sinemuriano inferior. Tradicionalmente se habia considerado queen la regi6n el Jur~sico marino comenzaba con el Sinemuriano superior. Representantes de los g~neros Psiloceras Hyatt, Caloceras Hyatt, Alsatites Haug, Waehneroceras Hyatt, Schlotheimia Bayle, Sulciferites Spath, Badouxia Guex y Taylor, Vermiceras Hyatt, Coroniceras Hyatt, Agassiceras Hyatt, Euagassieeras Spath y Arnioceras Hyatt, indican la presencia de estratos equivalentes alas zonas de Planorhis, Liasieus, Angulata, Bucklandi, Semicostatum y Turneri de la Escala Cronoestratigrafica Internacional. Asi en Argentina el Hettangiano, Sinemuriano, y Pliensbachiano basal marinos solamente han sido comprobados en proximidades de la regi6n del rio Atuel, donde tambi~n podrian hallarse representados niveles de Tri~sico marino. En el resto de Argentina los niveles m~s antiguos portadores de amonites del Jur~isico corresponden generalmente al Pliensbachiano inferior alto o Pliensbachiano superior. Desde el punto de vista regional estos hallazgos determinan una modificaci6n substancial en la paleogeografia del Jur~sico temprano de America del Sur.Facultad de Ciencias Naturales y Muse

    Non-isothermal curing of epoxy-epoxidized soybean oil-anhydride mixtures

    Get PDF
    Se estudió la cinética de curado no-isotérmico de mezclas de diglicidil éter de bisfenol A (DGEBA) con aceite de soja epoxidado (ESO) utilizando anhídrido metiltetrahidroftálico (MTHPA) como agente de curado y 1-metil imidazol (1MI) como iniciador. El sistema ESO/MTHPA exhibió valores de entalpía de reacción menores y temperaturas de pico exotérmico mayores que el sistema DGEBA/MTHPA debido a la menor reactividad de los grupos oxirano internos del ESO. Los parámetros cinéticos de los sistemas puros DGEBA/MTHPA y ESO/MTHPA se obtuvieron a partir de los datos calorimétricos mediante un análisis de regresión multiparamétrica utilizando un modelo cinético fenomenológico. La cinética de los sistemas puros fue utilizada para predecir la de las mezclas considerando las interacciones entre DGEBA y ESO. El modelo propuesto permitió predecir adecuadamente la cinética del proceso de curado utilizando parámetros independientes de la velocidad de calentamiento y de aplicación directa en el campo de procesamiento de estos materiales.Non-isothermal curing kinetics of mixtures of diglycidyl ether of bisphenol A (DGEBA) with epoxidized soybean oil (ESO) using methyl-tetrahydrophthalic anhydride (MTHPA) as curing agent and 1-methyl imidazole (1MI) as initiator was studied. The ESO/MTHPA system exhibited lower reaction enthalpy and higher peak temperatures values than DGEBA/MTHPA synthetic system due to the lower reactivity of internal oxirane groups in ESO. The kinetic parameters of pure systems ESO/MTHPA and DGEBA/MTHPA were obtained from the calorimetric data through a multiparametric regression analysis using a phenomenolgical kinetic model. The kinetics of pure systems was used to predict that of the mixtures taking into account the interactions between DGEBA and ESO. The proposed pattern allowed to predict appropriately the kinetics of the curing process using independent parameters of the heating speed and of direct application in the field of processing these materials.Fil: Altuna, Facundo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones En Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones En Ciencia y Tecnología de Materiales; ArgentinaFil: Riccardi, Carmen Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones En Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones En Ciencia y Tecnología de Materiales; ArgentinaFil: Ruseckaite, Roxana Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones En Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones En Ciencia y Tecnología de Materiales; ArgentinaFil: Stefani, Pablo Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones En Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones En Ciencia y Tecnología de Materiales; Argentin

    Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia

    Get PDF
    Nucleophosmin (NPM1) is a multifunctional protein that is implicated in the pathogenesis of several human malignancies. To gain insight into the role of isolated fragments of NPM1 in its biological activities, we dissected the C-terminal domain (CTD) into its helical fragments. Here we focus the attention on the third helix of the NPM1-CTD in its wild-type (H3 wt) and AML-mutated (H3 mutA and H3 mutE) sequences. Conformational studies, by means of CD and NMR spectroscopies, showed that the H3 wt peptide was partially endowed with an a-helical structure, but the AML-sequences exhibited a lower content of this conformation, particularly the H3 mutA peptide. Thioflavin T assays showed that the H3 mutE and the H3 mutA peptides displayed a significant aggregation propensity that was confirmed by CD and DLS assays. In addition, we found that the H3 mutE and H3 mutA peptides, unlike the H3 wt, were moderately and highly toxic, respectively, when exposed to human neuroblastoma cells. Cellular localization experiments confirmed that the mutated sequences hamper their nucleolar accumulation, and more importantly, that the helical conformation of the H3 region is crucial for such a localization
    • ‚Ķ
    corecore