557 research outputs found

    Sweet proteins – Potential replacement for artificial low calorie sweeteners

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    Exponential growth in the number of patients suffering from diseases caused by the consumption of sugar has become a threat to mankind's health. Artificial low calorie sweeteners available in the market may have severe side effects. It takes time to figure out the long term side effects and by the time these are established, they are replaced by a new low calorie sweetener. Saccharine has been used for centuries to sweeten foods and beverages without calories or carbohydrate. It was also used on a large scale during the sugar shortage of the two world wars but was abandoned as soon as it was linked with development of bladder cancer. Naturally occurring sweet and taste modifying proteins are being seen as potential replacements for the currently available artificial low calorie sweeteners. Interaction aspects of sweet proteins and the human sweet taste receptor are being investigated

    Note on the Pulsating Flow on n-Incompressible and Immiscible Rarefied Gases Between Two Plates

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    An investigation is made to study the unsteady viscous flow of n-immiscible and incompressible rarefied gases, occupying equal heights between parallel and stationary plates under the influence of a periodic pressure gradient superposed on the steady laminar flow. Expressions for velocity distributions have been obtained in exact form. The effects of the rarefaction parameter on the velocity distribution have been graphically when there are only two gases

    Sweet proteins – Potential replacement for artificial low calorie sweeteners

    Get PDF
    Exponential growth in the number of patients suffering from diseases caused by the consumption of sugar has become a threat to mankind's health. Artificial low calorie sweeteners available in the market may have severe side effects. It takes time to figure out the long term side effects and by the time these are established, they are replaced by a new low calorie sweetener. Saccharine has been used for centuries to sweeten foods and beverages without calories or carbohydrate. It was also used on a large scale during the sugar shortage of the two world wars but was abandoned as soon as it was linked with development of bladder cancer. Naturally occurring sweet and taste modifying proteins are being seen as potential replacements for the currently available artificial low calorie sweeteners. Interaction aspects of sweet proteins and the human sweet taste receptor are being investigated

    Interrelationship between Personality Traits and Emotional Intelligence of Secondary Teachers in India

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    Emotional intelligence is an ability to control our emotions in abnormal situations. Now it is widely accepted that emotional intelligence also a key determent for success and also in development in personality. Personality is a sum total of emotions. By taking a sample of 200 secondary school teachers an attempt has made to find out the relationship between emotional intelligence and different factors of personality of secondary school teachers. Results indicate that there is no significant difference between emotional intelligence of secondary school teachers in relation to gender and stream in which they are teaching. Further, a positive relationship found in the emotional intelligence and some of personality factors but many personality factors were negatively related to emotional intelligence of different groups of secondary school teachers but most type of relationship was not significant.DOI: http://dx.doi.org/10.11591/ijere.v3i3.614

    Mucosal membranes, their interactions to microbial infections and immune susceptibility in human hosts

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    This article presents mucosal immune defense in response to various pathogenic infections in different hosts including man. Internally, the mucosal layer (membrane) covers the respiratory, digestive, nasal, and urogenital systems and serves as a physical barrier against many groups of infections. The host pathogen's interaction with membrane receptors is highlighted in this article, as well as the commensal gut microbiota's protective function in directing both general and targeted immune defense. In order to combat numerous diseases of various types, this review emphasizes the importance of crosstalk between mucosal locations, mucosal adjuvant design, and antigen delivery mechanisms. Additionally, it denotes the function of inflammasomes, lipocalin 2, Muc2 hyaluronan, and probiotics in maintaining homeostasis, regulating the gut microbiota, and enhancing immunological protection against enteric infection and gastrointestinal inflammation. For novel potential vaccines that could activate innate and adaptive immunity in mucosal tissue, there is an urgent need to look for new protective antigens, delivery mechanisms, and mucosal adjuvants. In order to prevent the spread of infections that are drug-resistant, seek protection, and assure host immunological tolerance, this article emphasizes the necessity for new antigens in the construction of new vaccines. DOI: http://dx.doi.org/10.5281/zenodo.769367

    Nutritional and Therapeutic Potential of Allium Vegetables

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    Allium vegetables are highly nutritional, its dietary use improves digestion and mental health and lower down cholesterol level. Use of onions, garlic, scallions, chives and leeks show therapeutic efficacy against cardiovascular disease, hyperglycemia, and stomach cancer, Onions contain allylsulfides and flavonoids particularly quercetin that is an important anti-oxidative and reduces hepatocytes apoptosis in streptozotocin-induced diabetic rat. Steroid saponins and sapogenins present in garlic bulbs are used to prepare soft soaps. β-chlorogenin is a characteristic steroid sapogenin from garlic that is used for skin ointment and as a shiner. Both garlic paste and soft garlic preparations are used for flavoring the food items. Garlic products that contain the most safe, effective, stable, and odorless components are the most valuable as dietary supplements. Garlic also contains non sulfur compounds such as steroid saponins. Alliums showed antimicrobial, antithrombotic, antitumor, anti-hyperlipidaemic, antiarthritic, anti-hyperglycemic anticarcinogenic potential. Allium vegetables contain organosulfur compounds, including DATS, diallyl disulfide (DADS), ajoene, and S-allylmercaptocysteine (SAMC), have been found to induce cell cycle arrest in cancer cells. Alliums have great ethnomedicinal importance as these are used as native remedies against wide spectrum of diseases including diabetes. Allium origin natural products are of great therapeutic and dietary use. These are most preferred items used by nutritionists, physicians, food technologists, food chemists. Green allium vegetables are good source of natural pharmaceutics which are good for health and act against nutritionally induced acute and chronic diseases. Their possible inclusion in diets could explore new therapeutic avenues to enhance immunity against diseases

    Climate Induced Virus Generated Communicable Diseases: Management Issues and Failures

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    In the present review article human diseases caused by various groups of pathogens have been explained with its etiology, epidemiology and treatment. In addition, effect of climatic changes on parasites and pathogens has been demarcated with rising incidences of diseases. In response to environmental changes, mainly external and internal microenvironment of body and drug regimens taken by patients; virus is regularly changing its form and new mutant variants are coming out. These are circulating in many Indian states and cross border countries and causing high infectivity and mortality in human patients. These variants with new mutations are challenging existing drugs and other prophylactic measures and massively disrupting functions of a tissue, organ, or entire organism. Diseases caused by viruses are showing new trends in virulence, with high infectivity, morbidity and mortality. Due to climatic effect and drug resistance and new mutations in pathogens disease burden has been exacerbated enormously at global level. In all cases of helminthes, protozoan’s, fungi, bacteria, virus pathogens and parasites available drug structure seem to be failed or their usefulness has been much reduced due to evolution of new mutant variants with multiple drug resistance. There are serious failures at the level of operation, management and control of disease. The utmost failure is due to lack of appropriate vaccine, drug regimens, clinical care and awareness among people. These are major reasons that is why diseases become uncontrolled and unmanageable

    Biomechanics of the Small Intestinal Contractions

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    The small intestine is a part of the gastrointestinal segment comprising of the duodenum, jejunum, and ileum. They help to process the gastric contents for further digestion, which involves mixing with duodeno-biliary-pancreatic (DBP) secretions to facilitate the chemical digestion, and homogenization of the luminal contents through contractions of the circular and longitudinal smooth muscle fibers of the intestine. The contractions of these smooth muscle fibers develops the mechanical forces at the mucosal wall, which as a consequence, transfers its momentum to the underlying fluid to develop the fluid flows, suggesting relevance of mechanics in physiology. The resulting flows are what drive the digestion. Changes in contractility of wave shapes of circular and longitudinal smooth muscle contractions and fluid rheology are known to affect the digestive process through generation of various flow patterns that differ in luminal pressure, peak velocity, extent of shearing/ mixing, volume of mixing, and flow rate. Recent studies indicate that the digestive process can be very specific such as to cause lipid digestion through segmental contractions and transport by eliciting propagating contractions, suggesting that the intestine manages to digest a variety of food in an efficient manner by eliciting appropriate contractions
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