10 research outputs found

    La formaci√≥n del profesorado de espa√Īol en el estado de Georgia, EE.UU. An√°lisis y propuestas de mejora

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    Esta tesis analiza la formaci√≥n lingu√≠stica y pedag√≥gica del profesorado de espa√Īol como lengua extranjera en el estado de Georgia. Se han observado los diferentes aspectos y retos relacionados con la ense√Īanza del espa√Īol en el sistema escolar, y luego se ha hecho un estudio emp√≠rico con el prop√≥sito de observar la evaluaci√≥n hecha por el profesorado acerca de la preparaci√≥n lingu√≠stica y pedag√≥gica para la carrera docente. Se han preparado dos cuestionarios: uno al profesorado del sistema p√ļblico escolar y otro al profesorado que imparte cursos de espa√Īol en las universidades. Al final, se han confirmado las siguientes hip√≥tesis: los profesores no hispanohablantes, que se grad√ļan con una licenciatura en la ense√Īanza de E/LE, no se grad√ļan preparados para ense√Īar los cursos de espa√Īol AP y BI, y tampoco se grad√ļan preparados para impartir los cursos de espa√Īol para hispanohablantes en el sisema escolar. Estos resultados han demostrado que los programas de formaci√≥n del profesorado de E/LE no proveen una preparaci√≥n lingu√≠stica adecuada que asegure un nivel de fluidez deseado para los retos de la profesi√≥n docente. Se concluye que es necesario proveer m√°s posibilidades para el desarrollo lingu√≠stico del futuro profesor, y se reflexiona sobre algunas propuestas de mejora

    Institutional Evils, Culpable Complicity, and Duties to Engage in Moral Repair

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    Apology is arguably the central act of the reparative work required after wrongdoing. Claudia Card‚Äôs (1940-2015) analysis of complicity in collectively perpetrated evils moves one to ask whether apology ought to be requested of persons culpably complicit in institutional evils. To better appreciate the benefits of and barriers to apologies offered by culpably complicit wrongdoers, this article examines doctors‚Äô complicity in a practice that meets Card‚Äôs definition of an evil, namely, the non-medically necessary, nonconsensual ‚Äúnormalizing‚ÄĚ interventions performed on babies born with intersex anatomies. It argues that in this instance, the complicity of doctors is culpable on Card‚Äôs terms, and that their culpable complicity grounds rightful demands for them to apologize

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ‚ąľ99% of the euchromatic genome and is accurate to an error rate of ‚ąľ1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK ‚ÄėAlert Level 4‚Äô phase of the B-MaP-C study

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    Abstract: Background: The B-MaP-C study aimed to determine alterations to breast cancer (BC) management during the peak transmission period of the UK COVID-19 pandemic and the potential impact of these treatment decisions. Methods: This was a national cohort study of patients with early BC undergoing multidisciplinary team (MDT)-guided treatment recommendations during the pandemic, designated ‚Äėstandard‚Äô or ‚ÄėCOVID-altered‚Äô, in the preoperative, operative and post-operative setting. Findings: Of 3776 patients (from 64 UK units) in the study, 2246 (59%) had ‚ÄėCOVID-altered‚Äô management. ‚ÄėBridging‚Äô endocrine therapy was used (n = 951) where theatre capacity was reduced. There was increasing access to COVID-19 low-risk theatres during the study period (59%). In line with national guidance, immediate breast reconstruction was avoided (n = 299). Where adjuvant chemotherapy was omitted (n = 81), the median benefit was only 3% (IQR 2‚Äď9%) using ‚ÄėNHS Predict‚Äô. There was the rapid adoption of new evidence-based hypofractionated radiotherapy (n = 781, from 46 units). Only 14 patients (1%) tested positive for SARS-CoV-2 during their treatment journey. Conclusions: The majority of ‚ÄėCOVID-altered‚Äô management decisions were largely in line with pre-COVID evidence-based guidelines, implying that breast cancer survival outcomes are unlikely to be negatively impacted by the pandemic. However, in this study, the potential impact of delays to BC presentation or diagnosis remains unknown

    Justicia para las Mujeres

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    Poster (one week

    La integraci√≥n del contenido ling√ľ√≠stico y pedag√≥gico en el programa de formaci√≥n inicial del profesorado de ELE en el estado de Georgia, EEUU

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    Este estudio ha propuesto conocer la opini√≥n de los profesores universitarios de espa√Īol en el estado de Georgia sobre la formaci√≥n ling√ľ√≠stica y pedag√≥gica de sus estudiantes para la ense√Īanza de E/LE en el sistema escolar p√ļblico. Asimismo, este trabajo propuso investigar la disponibilidad de dicho profesorado universitario para impartir un curso pedag√≥gico en espa√Īol en lugar de en ingl√©s. De esta manera, se podr√≠a fomentar la competencia ling√ľ√≠stica del futuro profesor de E/LE mientras adquiere las destrezas pedag√≥gicas necesarias para la carrera docente. Como instrumento de investigaci√≥n, se ha preparado un cuestionario para entrevistar a los profesores de espa√Īol del sistema universitario de ese estado. Los resultados han comprobado que la mayor√≠a de los profesores entrevistados no cree que sus estudiantes se grad√ļen con una preparaci√≥n ling√ľ√≠stica adecuada para impartir todos los cursos de espa√Īol que son ofrecidos en el sistema escolar p√ļblico. Tambi√©n, la mayor√≠a de los participantes cree que ser√≠a recomendable ofrecer un curso pedag√≥gico impartido en espa√Īol en lugar de ingl√©s. Se ha observado que el 33% de los profesores entrevistados estar√≠a disponible para impartir tal curso, lo que tambi√©n posibilitar√≠a una mayor integraci√≥n entre los departamentos de lenguas extranjeras y los departamentos de educaci√≥n en el sistema universitario norteamericano

    La Belleza de la Cultura Mexicana

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    Amount of time involved: 28 hour

    COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study

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    Background Patients with cancer are purported to have poor COVID-19 outcomes. However, cancer is a heterogeneous group of diseases, encompassing a spectrum of tumour subtypes. The aim of this study was to investigate COVID-19 risk according to tumour subtype and patient demographics in patients with cancer in the UK. Methods We compared adult patients with cancer enrolled in the UK Coronavirus Cancer Monitoring Project (UKCCMP) cohort between March 18 and May 8, 2020, with a parallel non-COVID-19 UK cancer control population from the UK Office for National Statistics (2017 data). The primary outcome of the study was the effect of primary tumour subtype, age, and sex and on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) prevalence and the case‚Äďfatality rate during hospital admission. We analysed the effect of tumour subtype and patient demographics (age and sex) on prevalence and mortality from COVID-19 using univariable and multivariable models. Findings 319 (30¬∑6%) of 1044 patients in the UKCCMP cohort died, 295 (92¬∑5%) of whom had a cause of death recorded as due to COVID-19. The all-cause case‚Äďfatality rate in patients with cancer after SARS-CoV-2 infection was significantly associated with increasing age, rising from 0¬∑10 in patients aged 40‚Äď49 years to 0¬∑48 in those aged 80 years and older. Patients with haematological malignancies (leukaemia, lymphoma, and myeloma) had a more severe COVID-19 trajectory compared with patients with solid organ tumours (odds ratio [OR] 1¬∑57, 95% CI 1¬∑15‚Äď2¬∑15; p<0¬∑0043). Compared with the rest of the UKCCMP cohort, patients with leukaemia showed a significantly increased case‚Äďfatality rate (2¬∑25, 1¬∑13‚Äď4¬∑57; p=0¬∑023). After correction for age and sex, patients with haematological malignancies who had recent chemotherapy had an increased risk of death during COVID-19-associated hospital admission (OR 2¬∑09, 95% CI 1¬∑09‚Äď4¬∑08; p=0¬∑028). Interpretation Patients with cancer with different tumour types have differing susceptibility to SARS-CoV-2 infection and COVID-19 phenotypes. We generated individualised risk tables for patients with cancer, considering age, sex, and tumour subtype. Our results could be useful to assist physicians in informed risk‚Äďbenefit discussions to explain COVID-19 risk and enable an evidenced-based approach to national social isolation policies
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