635 research outputs found

    Detection of IgG against Rickettsia typhi: a population-based study in southern Kazakhstan

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    Uvod. Rickettsia typhi svrstava se u skupinu pjegavih tifusa i uzrokuje endemski tifus. Sluńćajevi endemskog tifusa i seropozitivnosti na R. typhi zabiljeŇĺeni su u susjednoj Kini i Rusiji. MeńĎutim, o endemskom tifusu u Kazahstanu se malo zna. Svrha ove studije bila je procijeniti prevalenciju IgG protutijela na R. typhi u populaciji juŇĺne regije Kazahstana. Metode. U istraŇĺivanje je ukljuńćeno ukupno 253 osoba (142 Ňĺena, 111 muŇ°karaca) u dobi od 1 do 71 godine. Detekcija serumskih IgG protutijela na R. typhi provedena je imunoenzimskim ELISA testom. Rezultati. Ukupna seropozitivnost na R. typhi iznosila je 34,4%. Najveńáa seroprevalencija od 91,8% zabiljeŇĺena je u regiji Turkestan. NajniŇĺa seropozitivnost od 6,1% otkrivena je u selu Lepsinsk, regija Almaty. Seroprevalencija se nije znańćajno razlikovala prema spolu. Seropozitivnost kod odraslih pojedinaca nije bila znańćajno povezana s dobi, ali pozitivni rezultati nisu otkriveni u dobnoj skupini djece mlańĎe od 14 godina. Zakljuńćak. Dobiveni rezultati potvrńĎuju aktivnu cirkulaciju R. typhij u regijama Turkestan i Almaty u Kazahstanu. Podaci ukazuju na hitnu potrebu za daljnjim istraŇĺivanjima ńćiji je cilj procijeniti klinińćki uńćinak R. typhi u juŇĺnoj regiji Kazahstana.Background. Rickettsia typhi belongs to the typhus group of rickettsiae and causes endemic typhus. Cases of endemic typhus and seropositivity to R. typhi have been reported in the neighbouring China and Russia. However, little is known of the endemic typhus in Kazakhstan. The purpose of this study was to evaluate the prevalence of IgG antibodies to R. typhi in the population of southern region of Kazakhstan. Methods. A total of 253 individuals (142 women, 111 men) aged from 1 to 71 years were recruited into the study. Detection of serum IgG antibodies against R. typhi was performed by enzyme-linked immunosorbent assay (ELISA). Results. The overall R. typhi seropositivity has reached 34.4%. The highest seroprevalence of 91.8% was recorded in the Turkestan Region. The lowest seropositivity of 6.1% was detected in the village Lepsinsk, Almaty Region. The seroprevalence did not differ significantly between genders. Seropositivity in adult individuals was not significantly associated with age, but positive results were not detected in the age group of children under 14 years. Conclusion. The obtained results confirm active circulation of R. typhi in the Turkestan and Almaty Regions of Kazakhstan. The data indicate an urgent need for further studies aimed to evaluate the clinical impact caused by R. typhi in the southern region of Kazakhstan

    Reception Test of Petals for the End Cap TEC+ of the CMS Silicon Strip Tracker

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    The silicon strip tracker of the CMS experiment has been completed and was inserted into the CMS detector in late 2007. The largest sub system of the tracker are its end caps, comprising two large end caps (TEC) each containing 3200 silicon strip modules. To ease construction, the end caps feature a modular design: groups of about 20 silicon modules are placed on sub-assemblies called petals and these self-contained elements are then mounted onto the TEC support structures. Each end cap consists of 144 such petals, which were built and fully qualified by several institutes across Europe. Fro

    Integration of the End Cap TEC+ of the CMS Silicon Strip Tracker

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    The silicon strip tracker of the CMS experiment has been completed and inserted into the CMS detector in late 2007. The largest sub-system of the tracker is its end cap system, comprising two large end caps (TEC) each containing 3200 silicon strip modules. To ease construction, the end caps feature a modular design: groups of about 20 silicon modules are placed on sub-assemblies called petals and these self-contained elements are then mounted into the TEC support structures. Each end cap consists of 144 petals, and the insertion of these petals into the end cap structure is referred to as TEC integration. The two end caps were integrated independently in Aachen (TEC+) and at CERN (TEC--). This note deals with the integration of TEC+, describing procedures for end cap integration and for quality control during testing of integrated sections of the end cap and presenting results from the testing

    Differential cross section measurements for the production of a W boson in association with jets in proton‚Äďproton collisions at ‚ąös = 7 TeV

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    Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript ‚ąí1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

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