19 research outputs found

    ENVIRONMENTAL SUSTAINABILITY APPRAISAL OF THE ATRIAL FIBRILLATION CARE PATHWAY

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    An appraisal of the Atrial Fibrillation care pathway regarding its environmental impact using environmental metrics of CO2 emissions, water use and waste production

    Practice Of Endodontic Re-Treatment In Four Cities Of Pakistan

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    Background: Root canal re-treatment is the procedure of choice when the primary root treatment fails but patient is inclined toward salvage of the tooth. The re-treatment is often a challenging procedure owing to lack to the predictability in the outcomes. Since, there is a no single way of planning and executing such procedure, a study was planned to assess the knowledge, attitude and practice regarding endodontic re-treatment among Pakistani dentists. The effect of clinical experience on the re-treatment planning was also determined.Methods: A survey was conducted by distributing a questionnaire among 240 dentists practicing in four major cities of Pakistan. Frequency distribution of the gender, experience, designation of the participants etc. was determined. A case scenario was also shared and responses upon decision making were noted. Chi square test was applied to see if re-treatment decision of experienced dentists (\u3e5 years\u27 practice) was significantly different than less experienced dentists.Results: Out of 240 forms, 160 were received (response rate of 66.67%). The most commonly reported reason for endodontic re-treatment was under prepared/ under filled canals. Nearly 40% participants reported doing re-treatment with hand instruments only and 15% did not employ any solvent during re-treatment. There were no significant differences between the less experienced and the more experienced dentists on re-treatment decisions.CONCLUSIONS: Almost half of the dentists reported inappropriate decision making in re-treatment. This shows that in endodontic re-treatment practice in major cities of Pakistan falls short of internationally accepted standards. There is a significant difference in treatment planning done by more experienced dentists compared to ones with \u3c5 \u3eyears\u27 clinical experience

    Remaining dentine thickness of root canals prepared with K-3 and ProTaper rotary systems

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    Objective: To compare the remaining dentine thickness of root canals prepared with K-3 and ProTaper files..Methods: This in-vitro experimental study was conducted from 1st April-30th September 2015 at the dental clinics of Aga Khan University Hospital, Karachi, and comprised human teeth. Extracted human premolars and molars were included in the study using non-probability consecutive sampling. Canals were randomly allocated into two groups i.e. K-3 and ProTaper. Changes in inner and outer walls of canals were measured using Vixwin software at 1mm, 4mm, 7mm and 10mm from the apex. SPSS 20 was used for data analysis.Results: Of the 214 canals, 107(50%) were assigned to each group. No statistically significant difference was found in the remaining dentine thickness at 1mm, 4mm, 7mm and 10mm from the apex of the teeth prepared with in K-3 versus ProTapers system (p\u3e0.05).CONCLUSIONS: The remaining dentine thickness of the root canals prepared with K-3 files was similar to that of canals prepared with ProTaper files

    Comparison of fracture and deformation in the rotary endodontic instruments: protaper versus K-3 system

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    Abstract This experimental study was done on extracted human teeth to compare the fracture and deformation of the two rotary endodontic files system namely K-3 and Protapers. It was conducted at the dental clinics of the Aga Khan University Hospital, Karachi, A log of file deformation or fracture during root canal preparation was kept. The location of fracture was noted along with the identity of the canal in which fracture took place. The fracture in the two rotary systems was compared. SPSS 20 was used for data analysis. Of the 172(80.4%) teeth possessing more than 15 degrees of curvature, fracture occurred in 7(4.1%) cases and deformation in 10(5.8%). Of the 42(19.6%) teeth possessing less than 15 degrees of curvature, fracture occurred in none of them while deformation was seen in 1(2.4%). There was no difference in K-3 and Protaper files with respect to file deformation and fracture. Most of the fractures occurred in mesiobuccal canals of maxillary molars, n=3(21.4%). The likelihood of file fracture increased 5.65-fold when the same file was used more than 3 times. Irrespective of the rotary system, apical third of the root canal space was the most common site for file fracture

    Recent developments in the understanding of NSAID-induced liver fibrosis: linking fundamental mechanisms to specific therapy ideas

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    One of the most often prescribed medicine class worldwide is that of non-steroidal anti-inflammatory drugs. NSAIDs exhibit the action of a common mechanism consisting of cyclooxygenase inhibition, the enzymes in charge of producing prostanoids. NSAIDs are primarily weak organic acids and have been connected to liver disease for multiple decades. Interstitial collagens are produced in excess and deposited in the liver's extracellular matrix, resulting in hepatic fibrosis. Only a few NSAIDs exhibit inherent dose-dependent toxicity. Dietary changes, alcohol abstinence, and antiviral drugs are examples of current therapy. Nevertheless, such etiology-driven treatment is typically inadequate in patients with late-stage fibrosis or cirrhosis. The development of practice guidelines by multidisciplinary panels of experts includes suggestions of helpful remedy options for the particular reason of liver injury, stage of fibrosis, or occurrence of co-morbidities linked to a continuing loss of liver function. We listed the causes of hepatic injuries, including NSAIDs, and the prevailing theories behind anti-fibrotic treatments

    Therapeutic Potential of Seaweed Bioactive Compounds

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    Edible seaweeds are rich in bioactive compounds such as soluble dietary fibers, proteins, peptides, minerals, vitamins, polyunsaturated fatty acids and antioxidants. Previously, seaweeds were only used as gelling and thickening agents in the food or pharmaceutical industries, recent researches have revealed their potential as complementary medicine. The red, brown and green seaweeds have been shown to have therapeutic properties for health and disease management, such as anticancer, antiobesity, antidiabetic, antihypertensive, antihyperlipidemic, antioxidant, anticoagulant, anti-inflammatory, immunomodulatory, antiestrogenic, thyroid stimulating, neuroprotective, antiviral, antifungal, antibacterial and tissue healing properties. In proposed chapter, we discussed various active compounds include sulphated polysaccharides, phlorotannins, carotenoids (e.g. fucoxanthin), minerals, peptides and sulfolipids, with proven benefits against degenerative metabolic diseases. Moreover, therapeutic modes of action of these bioactive components and their reports are summarized in this chapter

    Cellulose-based materials and their adsorptive removal efficiency for dyes: A review

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    Dyes are emerging as harmful pollutants, which is one of major issues for the environmentalists and there is a urgent need for the removal of dyes from the effluents. In this context, the adsorption technology has been extensively used as an effective tool for the removal of dyes from the aqueous phase. This technique uses low-cost adsorbents and the cellulosic material is a biodegradable, cost-effective and renewable polymer, which is not soluble in the majority of solvents because of its crystalline nature and hydrogen bonding. Currently, the modified cellulosic materials for the removal of dyes from wastewater gained much attention. Moreover, the application of cellulose for water treatment can be utilized for controlling pollution and have high economic viability and availability. This review signifies the use of cellulose-based adsorbent for dyes adsorption from wastewater. The key advancement in the preparation and modification of cellulose-based adsorbents is discussed and their adsorption efficiencies are compared with other adsorbents for removal of dyes and adsorption conditions are also considered for the same. The studies reporting cellulose-based adsorption from 2003 to 2022 are included and their various properties are compared for the efficient removal of dyes. The modified cellulosic materials cellulose is a highly effective adsorbent for the remediation of effluents

    ENVIRONMENTAL SUSTAINABILITY APPRAISAL OF THE ATRIAL FIBRILLATION CARE PATHWAY

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    An appraisal of the Atrial Fibrillation care pathway regarding its environmental impact using environmental metrics of CO2 emissions, water use and waste production

    Protection of Microgrid by Using Adaptive Relaying Scheme

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    International audienceRecently, different ideas are developed and implemented towards the interest of getting more effective low carbon energy sources and Microgrids. A microgrid has two modes of operations, Grid connected mode of operation and stand alone mode of operation. When the mode of operation is changed from grid connected mode to stand alone mode there is a drastic reduction in the magnitude of the fault current , so this mannerism and shows the problem with the protection .In order to overcome this sort of problem we develop this scheme. In this scheme the relays are made quite intelligent to decide the mode of operation of the system and to sense the expected faults on time. Relay shows a flexible behavior to the magnitude of the fault and change its setting according to the fault magnitude. Here is the demonstration of how to develop the hardware for the adaptive relays for the purpose of protection of microgrids, certain cases are also developed to validate its operation too. Relays adopts itself to the fault to adjust its setting and time of operation

    Monitoring mangrove forest degradation and regeneration: landsat time series analysis of moisture and vegetation indices at Rabigh Lagoon, Red Sea

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    Rabigh Lagoon, located on the eastern coast of the Red Sea, is an ecologically rich zone in Saudi Arabia, providing habitat to Avicennia marina mangrove trees. The environmental quality of the lagoon has been decaying since the 1990s mainly from sedimentation, road construction, and camel grazing. However, because of remedial measures, the mangrove communities have shown some degree of restoration. This study aims to monitor mangrove health of Rabigh Lagoon during the time it was under stress from road construction and after the road was demolished. For this purpose, time series of EVI (Enhanced Vegetation Index), MSAVI (Modified, Soil-Adjusted Vegetation Index), NDVI (Normalized Difference Vegetation Index), and NDMI (Normalized Difference Moisture Index) have been used as a proxy to plant biomass and indicator of forest disturbance and recovery. Long-term trend patterns, through linear, least square regression, were estimated using 30 m annual Landsat surface-reflectance-derived indices from 1986 to 2019. The outcome of this study showed (1) a positive trend over most of the study region during the evaluation period; (2) most trend slopes were gradual and weakly positive, implying subtle changes as opposed to abrupt changes; (3) all four indices divided the times series into three phases: degraded mangroves, slow recovery, and regenerated mangroves; (4) MSAVI performed best in capturing various trend patterns related to the greenness of vegetation; and (5) NDMI better identified forest disturbance and recovery in terms of water stress. Validating observed patterns using only the regression slope proved to be a challenge. Therefore, water quality parameters such as salinity, pH/dissolved oxygen should also be investigated to explain the calculated trends
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