21 research outputs found

    Machine learning issues and opportunities in ultrafast particle classification for label-free microflow cytometry

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    Machine learning offers promising solutions for high-throughput single-particle analysis in label-free imaging microflow cytomtery. However, the throughput of online operations such as cell sorting is often limited by the large computational cost of the image analysis while offline operations may require the storage of an exceedingly large amount of data. Moreover, the training of machine learning systems can be easily biased by slight drifts of the measurement conditions, giving rise to a significant but difficult to detect degradation of the learned operations. We propose a simple and versatile machine learning approach to perform microparticle classification at an extremely low computational cost, showing good generalization over large variations in particle position. We present proof-of-principle classification of interference patterns projected by flowing transparent PMMA microbeads with diameters of 15.2 mu m and 18.6 mu m. To this end, a simple, cheap and compact label-free microflow cytometer is employed. We also discuss in detail the detection and prevention of machine learning bias in training and testing due to slight drifts of the measurement conditions. Moreover, we investigate the implications of modifying the projected particle pattern by means of a diffraction grating, in the context of optical extreme learning machine implementations

    Silicon photonics for neuromorphic information processing

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    We present our latest results on silicon photonics neuromorphic information processing based a.o. on techniques like reservoir computing. We will discuss aspects like scalability, novel architectures for enhanced power efficiency, as well as all-optical readout. Additionally, we will touch upon new machine learning techniques to operate these integrated readouts. Finally, we will show how these systems can be used for high-speed low-power information processing for applications like recognition of biological cells

    Photonic neuromorphic information processing and reservoir computing

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    Photonic neuromorphic computing is attracting tremendous research interest now, catalyzed in no small part by the rise of deep learning in many applications. In this paper, we will review some of the exciting work that has been going in this area and then focus on one particular technology, namely, photonic reservoir computing

    Photonics-based machine learning to speed up and simplify label-free flow cytometry

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    Photonic reservoir computing: a brain-inspired approach for information processing (invited paper)

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    We present our latest results on silicon photonics neuromorphic information processing based on techniques like reservoir computing. We will discuss aspects like scalability, novel architectures for enhanced power efficiency, as well as all-optical readout. Additionally, we will touch upon new machine learning techniques to operate these integrated readouts
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