178 research outputs found

    Prediction of heart failure hospitalizations with wearable activity monitors

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    Sixty one patients of the Advanced Cardiac Care Center of Columbia University Medical Center diagnosed with congestive heart failure (CHF) wore Actical, an accelerometer device that continuously recorded physical activity over a seven to nine months period. Over the course of the study, twenty two subjects were either hospitalized or had an emergency room visit. The goal of this thesis is to explore whether ambulatory monitoring of physical activity with accelerometers predicts clinically relevant adverse events in CHF patients. We introduce novel actigraphy summaries and identify prevalent patterns that explain roughly 60 of all CHF related episodes. These patterns can be detected as early as two months to three weeks prior to an episode

    Low Carbon Energy Policy Research

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    AbstractCase study of Korea, Low carbon energy efficiency labeling schemes (Energy Efficiency Label and Standard Program, High efficiency Appliance Certification Program, e-Standby Program) play a key role in carrying out the energy efficiency improvement policy in the appliances and equipment sector in Korea. Korea operates these Programs in an effort to improve energy efficiency in appliances and equipments. Mandatory energy efficiency standard which bans production and sales of low energy efficiency products which fall below the minimum energy performance standard. Ministry of Knowledge of Economy (MKE) and Korea Energy Management Corporation (KEMCO) is the key organizations in implementing energy efficiency standards and labeling. National energy efficiency efforts can be realized through energy efficiency improvements with the successful implementation of an energy efficient appliances dissemination policy and the phase out of low efficiency appliances. Through the implementation of the Energy Efficiency Label and Standard Program (1992), High-efficiency Appliance Certification Program (1996) and e-Standby Program (1999), significant energy efficiency improvements have been achieved, and 1.37 billion USD worth of energy savings

    The Kriston AI System for the VoxCeleb Speaker Recognition Challenge 2022

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    This technical report describes our system for track 1, 2 and 4 of the VoxCeleb Speaker Recognition Challenge 2022 (VoxSRC-22). By combining several ResNet variants, our submission for track 1 attained a minDCF of 0:090 with EER 1:401%. By further incorporating three fine-tuned pre-trained models, our submission for track 2 achieved a minDCF of 0:072 with EER 1:119%. For track 4, our system consisted of voice activity detection (VAD), speaker embedding extraction, agglomerative hierarchical clustering (AHC) followed by a re-clustering step based on a Bayesian hidden Markov model and overlapped speech detection and handling. Our submission for track 4 achieved a diarisation error rate (DER) of 4.86%. The submissions all ranked the 2nd places for the corresponding tracks.Comment: System description of VoxSRC 2022: track 1, 2 and

    Effects of Rh-endostar in Combination with Radiotherapy on Rats with Lung Cancer

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    Background and objective Radiation sensitivity is closely related to tissue oxygen, and rh-endostatin can induce the high level of oxygen content in tumor by "normalizing" tumor angiogenesis which is associated with radiotherapy sensitivity. The aim of this study is to observe the effect of combination of radiotherapy with rh-endostatin in the rats with lung cancer. Methods Immediate lewis cancerous ascetic injection method was used to make rats tumors bearing model, then the rats was divided into four groups randomly: group A was treated with saline; group B was treated with rh-endostatin; group C was treated with irradiation and group D was treated with rh-endostatin and irradiation. After all rats were treated, inhibition rates and the tumor growth curve were calculated. Immunohistochemisty was adopted to check the expressions of vascular endothelial growth factor (VEGF) and microvessel density (MVD). Results Compared with group A, the growth rates of the tumors in the other group were obviously slower, and the tumor weights were significantly different form group A (P<0.05). Compared with the other groups, the tumor weights of group D were obviously reduced (P<0.05). Compared with group A, VEGF and MVD of other three groups were reduced (P<0.05), and group D were significantly cut down. Conclusion Combination with radiotherapy and rh-endostatin could inhibit the lung cancer significantly in rats. The possible mechanisms are to decrease the expression of VEGF and inhibit the production of angiogenesis

    SOME RESULTS ON (k, µ)'-ALMOST KENMOTSU MANIFOLDS

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    In this paper, we study the quasi-conformal curvature tensor C and projective curvature tensor P on a (k, µ)'-almost Kenmotsu manifold M^2n+1 of dimensiongreater than 3. We obtain that if M 2n+1 is non-Kenmotsu and satisfies R · C = 0 orP · P = 0, then it is locally isometric to the Riemannian product H^(n+1)(-4) × R^n

    Swashplateless-elevon Actuation for a Dual-rotor Tail-sitter VTOL UAV

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    In this paper, we propose a novel swashplateless-elevon actuation (SEA) for dual-rotor tail-sitter vertical takeoff and landing (VTOL) unmanned aerial vehicles (UAVs). In contrast to the conventional elevon actuation (CEA) which controls both pitch and yaw using elevons, the SEA adopts swashplateless mechanisms to generate an extra moment through motor speed modulation to control pitch and uses elevons solely for controlling yaw, without requiring additional actuators. This decoupled control strategy mitigates the saturation of elevons' deflection needed for large pitch and yaw control actions, thus improving the UAV's control performance on trajectory tracking and disturbance rejection performance in the presence of large external disturbances. Furthermore, the SEA overcomes the actuation degradation issues experienced by the CEA when the UAV is in close proximity to the ground, leading to a smoother and more stable take-off process. We validate and compare the performances of the SEA and the CEA in various real-world flight conditions, including take-off, trajectory tracking, and hover flight and position steps under external disturbance. Experimental results demonstrate that the SEA has better performances than the CEA. Moreover, we verify the SEA's feasibility in the attitude transition process and fixed-wing-mode flight of the VTOL UAV. The results indicate that the SEA can accurately control pitch in the presence of high-speed incoming airflow and maintain a stable attitude during fixed-wing mode flight. Video of all experiments can be found in youtube.com/watch?v=Sx9Rk4Zf7sQComment: 8 pages, 13 figure

    Contextual factors among indiscriminate or larger attacks on food or water supplies, 1946-2015

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    This research updates previous inventories of malicious attacks on food and water to include data from 1946 through mid-2015. A systematic search of news reports, databases and previous inventories of poisoning events was undertaken. Incidents that threatened or were intended to achieve direct harm to humans, and that were either relatively large (number of victims > 4 or indiscriminate in intent or realisation were included. Agents could be chemical, biological or radio-nuclear. Reports of candidate incidents were subjected to systematic inclusion and exclusion criteria as well as validity analysis (not always clearly undertaken in previous inventories of such attacks). We summarise contextual aspects of the attacks that may be important for scenario prioritisation, modelling and defensive preparedness. Opportunity is key to most realised attacks, particularly access to dangerous agents. The most common motives and relative success rate in causing harm were very different between food and water attacks. The likelihood that people were made ill or died also varied by food/water mode, and according to motive and opportunity for delivery of the hazardous agent. Deaths and illness associated with attacks during food manufacture and prior to sale have been fewer than those in some other contexts. Valuable opportunities for food defence improvements are identified in other contexts, especially food prepared in private or community settings

    Phytochemical compositions, antioxidant and antimicrobial activities analysis of extracts from <i>Vaccinium bracteatum</i> Thunb. leaves

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    Vaccinium bracteatum Thunb. is an edible plant, which has been used for many food products and is also a resource of traditional Chinese medicine. In this study, the antioxidant and antimicrobial activities of ethanol extracts from its leaves were investigated. To study the characteristic compositions, twelve compounds of extracts accumulated by the D-101 macroporous adsorption resin (VBE) were identified by HPLC-DAD and HPLC-ESI/MS techniques, including chlorogenic acid and its isomers, and eight flavonoid compounds. The contents of total flavonoids, orientin and isoorientin in the accumulated part were 601.4, 44.7, and 96.1 mg/g, respectively, which were far more than that in the raw materials. Furthermore, the antioxidant activities were estimated by DPPH, ABTS, and FRAP assays, which showed that the high content accompanied with strong antioxidant activities. Besides, compared to the same type of bamboo leaves (AOB), the accumulated part possesses better activities. At the last, the antimicrobial activities of VBE were assessed by a serial two-fold dilution assay, the results showed that it had good antimicrobial activities. Taken together, extracts from Vaccinium bracteaturn Thunb. leaves have better antioxidant activities, which can be used as a natural antioxidant

    Comparison among Reconstruction Algorithms for Quantitative Analysis of 11

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    Objective. Kinetic modeling of dynamic 11C-acetate PET imaging provides quantitative information for myocardium assessment. The quality and quantitation of PET images are known to be dependent on PET reconstruction methods. This study aims to investigate the impacts of reconstruction algorithms on the quantitative analysis of dynamic 11C-acetate cardiac PET imaging. Methods. Suspected alcoholic cardiomyopathy patients (N=24) underwent 11C-acetate dynamic PET imaging after low dose CT scan. PET images were reconstructed using four algorithms: filtered backprojection (FBP), ordered subsets expectation maximization (OSEM), OSEM with time-of-flight (TOF), and OSEM with both time-of-flight and point-spread-function (TPSF). Standardized uptake values (SUVs) at different time points were compared among images reconstructed using the four algorithms. Time-activity curves (TACs) in myocardium and blood pools of ventricles were generated from the dynamic image series. Kinetic parameters K1 and k2 were derived using a 1-tissue-compartment model for kinetic modeling of cardiac flow from 11C-acetate PET images. Results. Significant image quality improvement was found in the images reconstructed using iterative OSEM-type algorithms (OSME, TOF, and TPSF) compared with FBP. However, no statistical differences in SUVs were observed among the four reconstruction methods at the selected time points. Kinetic parameters K1 and k2 also exhibited no statistical difference among the four reconstruction algorithms in terms of mean value and standard deviation. However, for the correlation analysis, OSEM reconstruction presented relatively higher residual in correlation with FBP reconstruction compared with TOF and TPSF reconstruction, and TOF and TPSF reconstruction were highly correlated with each other. Conclusion. All the tested reconstruction algorithms performed similarly for quantitative analysis of 11C-acetate cardiac PET imaging. TOF and TPSF yielded highly consistent kinetic parameter results with superior image quality compared with FBP. OSEM was relatively less reliable. Both TOF and TPSF were recommended for cardiac 11C-acetate kinetic analysis
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