6 research outputs found

    Interrelations between changes in parameters of HRV, EEG and phagocytosis at patients with chronic pyelonephritis and cholecystitis

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    Background. Previously we have shown within the immunological homunculus conception that take place causal relationships between induced by balneotherapy changes in parameters of EEG and HRV, on the one hand, and the parameters of humoral and cellular immunity, on the other hand. The purpose of this study is to find out the relationships between induced by balneotherapy changes in parameters of EEG and HRV, on the one hand, and the parameters of phagocytosis , on the other hand. Material and methods. In basal conditions in 33 men and 10 women with chronic pyelonephritis and cholecystitis in remission, we recorded twice, before and after balneotherapy at the spa Truskavets‚Äô, EEG (‚ÄúNeuroCom Standard‚ÄĚ) and HRV (‚ÄúCardiolab+VSR‚ÄĚ). In blood estimated parameters of phagocytic function of neutrophils against Staphylococcus aureus and Escherichia coli. Results. Judging by the coefficients of canonical correlation, the maximal subordinate nervous regulation is the completeness of phagocytosis of E. coli (R=0,944), whereas the influence of the nervous system on the completeness of phagocytosis Staph. aur. is minimal (R=0,607). With regard to the intensity of phagocytosis, the differences in the strength of nerve influence are expressed less (0,893 vs 0,744), and in relation to the activity of phagocytosis as well as the bactericidal ability of neutrophils, there are no differences between R (0,858 vs 0,857 and 0,831 vs 0,834, respectively). However, significant differences were found between profiles of correlation coefficients between EEG and HRV parameters, on the one hand, and phagocytosis parameters, on the other hand, for representatives of Gram-negative and Gram-positive microbes. Conclusion. In the nervous regulation of phagocytosis by neutrophils of the Gram-negative and Gram-positive microbes are involved the structures that are localized in different parts of the CNS

    Relationships between caused by drinking of bioactive water Naftussya changes in urine lithogenicity and neuro-humoral-immune factors in humans with theirs abnormalities

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    Objective. Spa Truskavets' (Ukraine) considered to be indicated for the treatment and metaphylaxis renal stone disease. However, data on the effect of balneotherapy on the parameters of urine Lithogenicity ambiguous. This is due, perhaps, ambiguous influence balneotherapy on the neuroendocrine factors regulating exchange of electrolytes and uric acid. Aim: to find out the influence drinking of bioactive water Naftussya on urine lithogenicity and neuro-humoral-immune factors in humans with theirs abnormalities. Methods. The object of observation were ten women and ten men aged 33-76 years without clinical diagnose but with dysfunction of neuro-endocrine-immune complex and metabolism. In daily urine and blood we determined the content of electrolytes and nitrogenous metabolites, estimated parameters of immunity, recorded conductivity of acupuncture points and heart rate variability (HRV). After examination volunteers within 7 days used bioactive water Naftussya (250 ml three times a day), then repeated the tests listed. Results. Lithogenicity urine Index (Lith) calculated by formula: Lith=(Uric acid‚ÄĘCalcium/Magnesium‚ÄĘCreatinine)0,25. In 3 people initial normal Lith (0,65√∑0,81 units) increased by 0,08√∑0,16 units. In 4 people with normal or high Lith its changes were not detected (-0,01√∑+0,01). In 12 people from a wide range of primary Lith (0,62√∑1,07) it lowered by 0,03√∑0,12 un. Even in a man maximum level of Lith (1,45 un.) down to the upper limit of normal (0,84 un.). Found a strong correlation between changes in Lith and a number parameters of HRV, metabolism and immunity. Conclusion. The use of bioactive water Naftussya causes ambiguous changes in Lithogenicity of urine, related to ambiguous changes in HRV, metabolism and immunity

    Gas Discharge Visualization (Electrophotonic Imaging, Kirlianography). Theoretical and Applied Aspects, 189 s.

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    The monograph highlights the results of priority clinical-physiological studies of the relationships between gas discharge visualization (electrophotonic imaging, kirlianography) parameters, on the one hand, and electroencephalograms, heart rate variability, immunograms, phagocytosis, the content of the main adaptation hormones (cortisol, aldosterone, testosterone, triiodothyronine, calcitonin) in the blood as well as acupuncture points - on the other hand. It is shown that the GDV/EPI method reliably reflects the state of the body's neuro-endocrine-immune complex as well as others parameters and has the right to take its place in the arsenal of physiological/biophysical methods. For biophysicists, physiologists, psychophysiologists, endocrinologists, immunologists, medical rehabilitation specialists. INTRODUCTION Advances in biophysics, biology, functional genomics, neuroscience, psychology, psychoneuroimmunology, and other fields suggest the existence of a subtle system of ‚Äúbiofield‚ÄĚ interactions that organize biological processes from the subatomic, atomic, molecular, cellular, and organismic to the interpersonal and cosmic levels. Biofield interactions may bring about regulation of biochemical, cellular, and neurological processes through means related to electromagnetism, quantum fields, and perhaps other means of modulating biological activity and information flow. The biofield paradigm, in contrast to a reductionist, chemistry-centered viewpoint, emphasizes the informational content of biological processes; biofield interactions are thought to operate in part via low-energy or ‚Äúsubtle‚ÄĚ processes such as weak, nonthermal electromagnetic fields (EMFs) or processes potentially related to consciousness and nonlocality. Biofield interactions may also operate through or be reflected in more well-understood informational processes found in EEG and ECG data. Recent advances have led to the development of a wide variety of therapeutic and diagnostic biofield devices, defined as physical instruments best understood from the viewpoint of a biofield paradigm [Muehsam D et al, 2015]. Biofield devices comprise physical instruments that may be most clearly understood from the viewpoint of a biofield paradigm, and a large and diverse number of devices have been developed to measure or manipulate biofield interactions. These include both diagnostic devices (to measure biofield properties) and therapeutic devices (to manipulate biofield interactions). The study of biofield devices is at a nascent stage of development, and much further research is needed to determine clinical efficacy and elucidate the underlying mechanisms of action for many of the devices mentioned here. The biofield devices operate through a variety of modalities rather than a single mechanism. Some biofield devices function through well-understood mechanisms and are already widely used in clinical settings: for example, electroencephalography (EEG)- and electrocardiography (ECG)-based heart rate variability (HRV). Other devices appear to operate through mechanisms that are novel or incompletely understood. However, all of these devices share a common property: rather than functioning primarily in a reductionist, chemistry-centered manner, biofield devices function via the informational content of biological processes and can interact via low-energy or ‚Äúsubtle‚ÄĚ processes, including those potentially related to consciousness and nonlocality [Muehsam D et al, 2015]. Here Muehsam D et al [2015] provide a brief overview of the broad categories of biofield devices, with the goal being to stimulate further discussion and research. Authors describe those devices for which thay deemed that sufficient evidence exists to warrant mention. They chose to focus upon devices for which peer-reviewed scientific reports suggesting efficacy are available rather than conference proceedings or manufacturers' white papers. However, in the few cases that specific devices with sufficient promise and relevance lacked a peer-reviewed basis, authors have presented whatever evidence was available. Here, devices are organized according to mode of operation and these modalities include electromagnetic field (EMF)-light, EMF-heat, EMF-nonthermal, electrical current, vibration and sound, physical and mechanical, intentionality and nonlocality, gas and plasma, and other (mode of operation not well understood). Muehsam D et al [2015] deemed that gas discharge visualization (GDV) is an important example of the use of plasma in biofield science. Back in 1880 Nikola Tesla demonstrated that when placing the man in the high-frequency field around the body there is a bright glow [cit. by Korotkov KG, 2001]. In 1892 Nardkevych-Yodko YO recorded glow human hands on photographic plate [cit. by Ciesielska I, 2009]. However, a well-known method of "high-frequency photography" was due to spouses Kirlian SD&VH who in 1939 independently discovered this phenomenon [Kirlian SD & Kirlian VKh, 1961], later called "Kirlian‚Äôs effect". This technique has been called corona discharge photography [Boyers DG & Tiller WA, 1973], electrophotography [Earle L, 1975], electrography [Konikiewicz LW, 1979], GDV [Bankovskii NG et al, 1986]. In 1996 Korotkov KG created a new scientific approach, based on the digital videotechnics, modern electronics and computer processing quantitative data, called as method gas discharge visualization (GDV bioelectrography). Parallel uses the terms Kirlianography and Electrophotonic imaging (EPI) [Korotkov KG, 2001; 2007; 2014; Korotkov KG et al, 2002; Wisneski LA & Anderson L, 2009; Jakovleva E & Korotkov K, 2013]. Method of GDV, essence of which consists in registration of photoelectronic emission of skin, induced by high-frequency electromagnetic impulses, allows to estimate integrated psycho-somatic state of organism. The first base parameter of GDV is Area of Gas Discharge Image (GDI) in Right, Frontal and Left projections registered both with and without polyethylene filter. The second base parameter is a coefficient of form/shape (ratio of square of length of external contour of GDI toward his area), which characterizes the measure of serration/fractality of external contour. The third base parameter of GDI is Entropy, id est measure of chaos. It is considered that GDI, taken off without filter, characterizes the functional changes of organism, and with a filter characterizes organic changes. Program estimates also Energy and Asymmetry of virtual Chakras [Korotkov KG, 2001; 2007; 2014]. Nearly 1000 papers have been published (mostly in Russian) on GDV research and a few hundred more in the West. These intriguing data suggest that informatics based upon biofield measurement devices such as the GDV may be useful for gaining deeper understanding of disease states and guiding practitioners and their patients towards states of greater wellness [Muehsam D et al, 2015]. Without regard to the wideuse enough of method in medicine, psychology, valeology and others like that, he yields to the just criticizing for an insufficient physiology ground. There fore we put before itself sweep to analyse relationships between the parameters of GDV - from one side, and by the row of neurodynamics, endocrine, immune. psychophysiological, and other parameters - on the other hand

    Relationships between Popovych’s Adaptation Index and parameters of ongoiging HRV and EEG in patients with chronic pyelonephrite and cholecystite in remission

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    Petsyukh Stepan V., Petsyukh Marta S., Kovbasnyuk Marta M., Barylyak Liliya G., Zukow¬†Walery. Relationships between Popovych‚Äôs Adaptation Index and parameters of ongoiging HRV and EEG in patients with chronic pyelonephrite and cholecystite in remission. Journal of Education, Health and Sport. 2016;6(2):99-110. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.46076 http://ojs.ukw.edu.pl/index.php/johs/article/view/3382 https://pbn.nauka.gov.pl/works/714487 ¬† The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015). 755 Journal of Education, Health and Sport eISSN 2391-8306 7 ¬© The Author (s) 2016; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 01.01.2016. Revised 12.01.2016. Accepted: 31.01.2016. ¬† ¬† RELATIONSHIPS BETWEEN POPOVYCH‚ÄôS ADAPTATION INDEX AND PARAMETERS OF ONGOIGING HRV AND EEG IN PATIENTS WITH CHRONIC PYELONEPHRITE AND CHOLECYSTITE IN REMISSION ¬† Stepan V. Petsyukh1, Marta S. Petsyukh2, Marta M. Kovbasnyuk4, Liliya¬†G.¬†Barylyak3,4,¬†Walery Zukow5 ¬† 1Medical Rehabilitation Center ‚ÄúPerlyna Prykarpattya‚ÄĚ Ministry of Internal Affairs, Truskavets‚Äô, Ukraine ¬†¬†¬†¬†[email protected] 2Danylo Halyts‚Äôky«ź National Medical University, L‚Äôviv, Ukraine 3JSC ‚ÄúTruskavets‚Äôkurort‚ÄĚ, Truskavets‚Äô, Ukraine¬†¬† [email protected] 4Laboratory of Experimental Balneology, OO Bohomolets‚Äô Institute of Physiology NAS, Truskavets‚Äô, Kyiv¬†¬†¬†¬† [email protected] 5Faculty of Physical Education, Health and Tourism, Kazimierz Wielki University, Bydgoszcz, Poland¬† ¬†[email protected] ¬† Abstracts Background. The conception of general adaptation reactions of organism (GARO), created by Garkavi LKh, Kvakina –ēB and Ukolova MA in 1977 on the base of Selye H classic conception of stress and developed then by them (1998), and also by Radchenko –ě–ú (2004), sufficiently successfully used in medicine and valeology for the estimation of general condition of organism. The downside the concept was qualitative assessment of GIRO. So Popovych IL (2000, 2006) proposed to quantify the various GARO Adaptation Index, which significantly correlated with the levels of key hormones adaptation and HRV parameters as well as phagocytosis. Another disadvantage of the concept is the lack of EEG markers GARO. We set a goal to analyze the relationships Popovych‚Äôs Adaptation Index with parameters of HRV and EEG. Methods. In basal conditions in 22 men, patients with chronic pyelonephrite and cholecystite in remission, recorded twice during 9-11 days HRV (‚ÄúCardiolab+VSR‚ÄĚ, KhAI Medica, Ukraine) and EEG (‚ÄúNeuroCom Standard‚ÄĚ, KhAI Medica, Ukraine). In portion of blood counted up leukocytogram, on the basis of which determined Popovych‚Äôs Adaptation Index (PAI). Results. Registered 14 normal (harmonious) GARO, 20 premorbidic (disharmonious) GARO and only 9 reactions of superactivation, in the absence stress-reactions. Revealed the closest relationship between PAI and normalized Power Spectral Density (PSD) LF (r=0,44), Baevskiy‚Äôs Stress Index in Orthostase (r=0,41), Laterality Index PSD őł-Rhythm (r=-0,43), PSD ő≤-Rhythm in Right Occipital locus (r=-0,40). Canonical correlation between PAI, on the one hand, and the parameters of HRV and EEG, on the other hand, is strong: R=0,846; R2=0,716; Adjusted R2=0,628; F(10)=8,1; Ōá2(10)=47,3; p<10-5. Conclusion. Popovych‚Äôs Adaptation Index reflects the activity of a number of regulatory nerve structures. Keywords: general adaptation reactions, leukocytogram, index of adaptation by Popovych, HRV, EEG, correlations

    Neuro-immune relationships at patients with chronic pyelonephrite and cholecystite. Communication 2. Correlations between parameters EEG, HRV and Phagocytosis

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    Kul‚Äôchyns‚Äôkyi Andriy B, Kovbasnyuk Marta M, Korolyshyn Tetyana A, Kyjenko¬†Valeriy¬†M, Zukow Walery, Popovych Igor L. Neuro-immune relationships at patients with chronic pyelonephrite and cholecystite. Communication 2. Correlations between parameters EEG, HRV and Phagocytosis. Journal of Education, Health and Sport. 2016;6(10):377-401. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.163221 http://ojs.ukw.edu.pl/index.php/johs/article/view/3957 ¬† ¬† ¬† ¬† The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015). 755 Journal of Education, Health and Sport eISSN 2391-8306 7 ¬© The Author (s) 2016; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.10.2016. Revised 02.10.2016. Accepted: 21.10.2016. ¬† ¬† ¬† Neuro-immune relationships at patients with chronic pyelonephrite and cholecystite. Communication 2. Correlations between parameters EEG, HRV and Phagocytosis ¬† Andriy B Kul‚Äôchyns‚Äôkyi1, Marta M Kovbasnyuk2, Tetyana A Korolyshyn2, Valeriy M Kyjenko2, Walery Zukow3, Igor L Popovych2 ¬† 1Communal Hospital, Truskavets‚Äô, Ukraine¬† [email protected] 2Laboratory of Experimental Balneology, OO Bogomoletz Institute of Physiology NAS, Kyiv, Ukraine ¬†[email protected]¬†¬† [email protected] 3Faculty of Physical Education, Health and Tourism, Kazimierz Wielki University, Bydgoszcz, Poland ¬†[email protected] ¬† Abstracts Background. Previously, we have shown that blood level of Leukocytes and parameters of Leukocytogram significantly modulated by electrical activity some structures of central and autonomic nervous systems. In this study, we set a goal to analyse the relationships between parameters of EEG and HRV, on the one hand, and the parameters of phagocytosis, on the other hand. Methods. In basal conditions in 23 men, patients with chronic pyelonephrite and cholecystite in remission, recorded EEG (‚ÄúNeuroCom Standard‚ÄĚ, KhAI Medica, Ukraine) and HRV (‚ÄúCardiolab+VSR‚ÄĚ, KhAI Medica, Ukraine). In portion of venous blood estimated parameters of phagocytic function of neutrophils. Results. Revealed that canonical correlation between constellation EEG and HRV parameters form with Phagocytic Index 0,94 and 0,93 for E. coli and Staph. aureus respectively. However neural regulation Killing Index as well as Microbial Count significantly distinguished for Gram-negative and Gram-positive Bacteria: R form 0,99 and 0,84 versus 0,66 and 0,69 respectively. Integrated parameter Bactericidity Capacity of blood Neutrophills correlated with EEG and HRV parameters equally: R makes 0,89 and 0,93 respectively. Conclusion. Neutrophils phagocytic function subordinate modulation central and autonomic nervous systems. Keywords: HRV, EEG, Phagocytosis, Escherichia coli, Staph. aureus, correlations

    Features of immunity by various constellations of principal adaptation hormones and autonomous regulation in practically healthy people

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    Gozhenko Anatoliy I, Hrytsak Yaroslav L, Barylyak Liliya G, Kovbasnyuk Marta M, Tkachuk Svitlana P, Korolyshyn Tetyana A, Matiyishyn Galyna Yo, Zukow Walery, Popovych Igor L. Features of immunity by various constellations of principal adaptation hormones and autonomous regulation in practically healthy people. Journal of Education, Health and Sport. 2016;6(10):215-235. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.160979 http://ojs.ukw.edu.pl/index.php/johs/article/view/3936 ¬† ¬† ¬† ¬† The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015). 755 Journal of Education, Health and Sport eISSN 2391-8306 7 ¬© The Author (s) 2016; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.10.2016. Revised 02.10.2016. Accepted: 15.10.2016. ¬† ¬† ¬† FEATURES OF IMMUNITY BY VARIOUS CONSTELLATIONS OF PRINCIPAL ADAPTATION HORMONES AND AUTONOMOUS REGULATION IN PRACTICALLY HEALTHY PEOPLE ¬† Anatoliy I Gozhenko1, Yaroslav L Hrytsak2, Liliya G Barylyak2,3,4, Marta M Kovbasnyuk4, Svitlana P Tkachuk3, Tetyana A Korolyshyn4, Galyna Yo Matiyishyn3, Walery Zukow5, Igor L Popovych4 ¬† 1Ukrainian Scientific Research Institute of Transport Medicine Ministry of Health, Odesa¬† ¬†[email protected] 2Hotel Spa Complex ‚ÄúKarpaty‚ÄĚ, Truskavets‚Äô, Ukraine¬† [email protected] 3JSC ‚ÄúTruskavets‚Äôkurort‚ÄĚ, Truskavets‚Äô, Ukraine¬†¬† [email protected] 4Laboratory of Experimental Balneology, OO Bogomoletz Institute of Physiology NAS, Kyiv, Ukraine ¬†[email protected];¬†¬† [email protected] 5Faculty of Physical Education, Health and Tourism, Kazimierz Wielki University, Bydgoszcz, Poland ¬†[email protected] ¬† Abstracts Background. It is known that in practically healthy (without clinical diagnose) people constellations of principal Adaptation Hormones displays widely variability representing different gradations of health and premorbide states. Previously, we found at least four mutually separated groups of people (endocrine clusters). The aim of this study is to elucidate the characteristics of immunity in members of different neuroendocrine clusters. Material and research methods. We determined twice in ten women and ten men aged 33-76 years without clinical diagnose serum levels of Cortisol, Aldosterone, Triiodothyronine, Testosterone and Calcitonin (ELISA) as well as Bayevskiy‚Äôs Stress Index by HRV as markers of General Adaptation Reactions (GAR). Also used determined by Leukocytogram Popovych‚Äôs Strain and Adaptation Indices. Immune status evaluated on a set of I and II levels recommended by the WHO. Results. All 40 case was distributed among four neuroendocrine clusters. Cluster N1 contains 10% cases with drastically hypercortisolemia and increased Baevskiy‚Äôs Stress Index combined with moderately decreased level of Testosterone but normal levels of Triiodothyronine, Aldosterone and Calcitonin. It is accompanied by a significant supression of cellular immunity and insignificant activation of humoral immunity. 12,5% cases (Cluster N2) characterized moderately increased level of Cortisol and Triiodothyronine combined with moderately decreased level of Calcitonin but normal levels of Testosterone and Aldosterone. Despite the normal average level of Stress Index it ranges in a wide range. This is accompanied by negligible inhibition of cellular immunity and significant activation of humoral immunity. 32,5% cases (Cluster N3) characterized moderately increased level of Cortisol too while moderately decreased level of Triiodothyronine as well as Calcitonin and Testosterone combined with upper borderline level of Aldosterone and normal level of Stress Index. This is accompanied by a significant activation of humoral immunity without abnormalities of cellular immunity. In 45% cases (Cluster N4) neuro-hormonal costellation characterized upper borderline levels of Cortisol as well as Testosterone combined with normal levels others hormones and even slightly reduced level of Stress Index. This is accompanied by more pronounced activation of humoral immunity without abnormalities of cellular immunity. Conclusion. Various constellations of Neuroendocrine factors of General Adaptation Reactions accompanied by various constellations parameters of Immunity. Keywords: Cortisol, Aldosterone, Triiodothyronine, Testosterone, Calcitonin, HRV, Immunity, Relationships
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