4 research outputs found

    A list of scale insects (Hemiptera: Coccoidea) intercepted in quarantine on imported succulent plants in Korea 2006-2010

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    A list of scale insects (Hemiptera: Coccoidea) intercepted on imported succulent plants at the plant quarantine of Korea from 2006 to 2010 is provided. A total of 15 species belonging to four families are listed. Of the 15 species that were intercepted, some species are potential pests that could gain entry and establish in Korea through the importation of plant material. Current information on intercepted scale insects is required to alert inspectors at quarantine sites to look carefully at succulent plants to prevent the introduction of an exotic species

    A Checklist of Whiteflies (Hemiptera: Aleyrodidae) Intercepted on Imported Plants in Korea 2005–2013

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    An updated checklist is provided of 26 species of whiteflies intercepted on plants imported into Korea from 2005 to 2013. Brief diagnostic criteria and photographs of the intercepted species are given to assist in identifying intercepted specimens of whiteflies

    Tropomyosin-Related Kinase Fusions in Gastrointestinal Stromal Tumors

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    The canonical mutations in gastrointestinal stromal tumors (GISTs) are typically activating mutations in KIT and platelet-derived growth factor receptor alpha (PDGFRA). GISTs with non-canonical mutations are a heterogeneous group. Here, we examined tropomyosin-related kinase (TRK) fusion in GIST cases without KIT/PDGFRA mutations (KIT/PDGFRA wild-type (WT) GISTs). We retrospectively analyzed patients who were diagnosed with GISTs at the Yonsei Cancer Center, Severance Hospital, between January 1998 and December 2016. Thirty-one patients with KIT/PDGFRA WT GISTs were included in the analysis. TRK expression in tumor samples was assessed by pan-TRK immunohistochemistry (IHC), and the neurotrophic tyrosine receptor kinase (NTRK: the gene encoding TRK) rearrangement was analyzed by fluorescence in situ hybridization (FISH). IHC analyses revealed that five cases in this cohort exhibited a weak to moderate TRK expression. NTRK1 fusions were detected in three tumor samples, and two samples harbored NTRK3 fusions. The remaining 26 samples did not harbor NTRK fusions. Two types of NTRK fusions were detected, and the overall NTRK fusion frequency in KIT/PDGFRA WT GIST cases was 16% (5/31). Our data provide insights into the molecular alterations underpinning KIT/PDGFRA WT GISTs. More effort should be devoted to improve methods to identify this distinct disease subtype within the KIT/PDGFRA WT GIST group
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