489 research outputs found

    Genre-Based Approach in Business Translation Teaching

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    Genre-based teaching approach is a pedagogy based on genre and genre analysis theory. Based on this teaching approach, the paper puts forward a three-stage model appropriate for the teaching of business English reading. It develops teaching activities focusing on the schematic structure of a discourse. Its purpose is to make students know that the discourses with different genres have different communicative purposes and discourse structures. Through a theoretical analysis and empirical study of the model, it is concluded that genre-based teaching approach can effectively help students improve their ability of business English reading comprehension

    Characteristics of Winter Urban Heat Island in Budapest at Local and Micro Scale

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    Most of the urban heat island (UHI) researches focused on the phenomenon in summer. They mainly studied the causes, different functional areas, and possible mitigation measures to reduce the high temperature in urban areas. However, UHI also exists in winter, but there are a limited number of studies on winter UHI. The characteristics and causes of UHI in winter have not been received much attention or consideration yet. This study aims to characterize the UHI feature in winter in Budapest, Hungary, based on the analysis of land surface temperature (LST) in relation to the factors of elevation, slope exposure, residential type, and snow coverage. Five different Landsat images in the winter season were applied to detect the surface temperature; besides, pictures of the thermal camera at a micro-scale were also used. Results showed that UHI intensity was not strong in winter; built-up areas were warmer than other urban areas. Topography was one of the significant factors affecting the surface temperature in winter. The surface temperature of the hills (300 m asl) was lower than that of the lowlands (below 120 m asl). The south-facing slopes and south oriented buildings were warmer than north-facing slopes and buildings oriented to the north. Areas with snow coverage had a lower temperature than no snow coverage areas. These findings could give general guidance for further UHI research, urban planning as well as landscape design

    Liver fatty acid composition in mice with or without nonalcoholic fatty liver disease

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    <p>Abstract</p> <p>Background</p> <p>Nonalcoholic fatty liver disease (NAFLD) is one of the most frequent causes of abnormal liver function. Because fatty acids can damage biological membranes, fatty acid accumulation in the liver may be partially responsible for the functional and morphological changes that are observed in nonalcoholic liver disease. The aim of this study was to use gas chromatography-mass spectrometry to evaluate the fatty acid composition of an experimental mouse model of NAFLD induced by high-fat feed and CCl<sub>4 </sub>and to assess the association between liver fatty acid accumulation and NAFLD. C57BL/6J mice were given high-fat feed for six consecutive weeks to develop experimental NAFLD. Meanwhile, these mice were given subcutaneous injections of a 40% CCl<sub>4</sub>-vegetable oil mixture twice per week.</p> <p>Results</p> <p>A pathological examination found that NAFLD had developed in the C57BL/6J mice. High-fat feed and CCl<sub>4 </sub>led to significant increases in C14:0, C16:0, C18:0 and C20:3 (P < 0.01), and decreases in C15:0, C18:1, C18:2 and C18:3 (P < 0.01) in the mouse liver. The treatment also led to an increase in SFA and decreases in other fatty acids (UFA, PUFA and MUFA). An increase in the ratio of product/precursor n-6 (C20:4/C18:2) and n-3 ([C20:5+C22:6]/C18:3) and a decrease in the ratio of n-6/n-3 (C20:4/[C20:5+C22:6]) were also observed.</p> <p>Conclusion</p> <p>These data are consistent with the hypothesis that fatty acids are deranged in mice with non-alcoholic fatty liver injury induced by high-fat feed and CCl<sub>4</sub>, which may be involved in its pathogenesis and/or progression via an unclear mechanism.</p

    Long distance transmission in few-mode fibers

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    Using multimode fibers for long-haul transmission is proposed and demonstrated experimentally. In particular few-mode fibers (FMFs) are demonstrated as a good compromise since they are sufficiently resistant to mode coupling compared to standard multimode fibers but they still can have large core diameters compared to single-mode fibers. As a result these fibers can have significantly less nonlinearity and at the same time they can have the same performance as single-mode fibers in terms of dispersion and loss. In the absence of mode coupling it is possible to use these fibers in the single-mode operation where all the data is carried in only one of the spatial modes throughout the fiber. It is shown experimentally that the single-mode operation is achieved simply by splicing single-mode fibers to both ends of a 35-km-long dual-mode fiber at 1310 nm. After 35 km of transmission, no modal dispersion or excess loss was observed. Finally the same fiber is placed in a recirculating loop and 3 WDM channels each carrying 6 Gb/s BPSK data were transmitted through 1050 km of the few-mode fiber without modal dispersion

    Genetic mapping of complex traits by minimizing integrated square errors

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    <p>Abstract</p> <p>Background</p> <p>Genetic mapping has been used as a tool to study the genetic architecture of complex traits by localizing their underlying quantitative trait loci (QTLs). Statistical methods for genetic mapping rely on a key assumption, that is, traits obey a parametric distribution. However, in practice real data may not perfectly follow the specified distribution.</p> <p>Results</p> <p>Here, we derive a robust statistical approach for QTL mapping that accommodates a certain degree of misspecification of the true model by incorporating integrated square errors into the genetic mapping framework. A hypothesis testing is formulated by defining a new test statistics - energy difference.</p> <p>Conclusions</p> <p>Simulation studies were performed to investigate the statistical properties of this approach and compare these properties with those from traditional maximum likelihood and non-parametric QTL mapping approaches. Lastly, analyses of real examples were conducted to demonstrate the usefulness and utilization of the new approach in a practical genetic setting.</p

    2-Amino-4-[4-(dimethyl­amino)­phen­yl]-5-oxo-5,6,7,8-tetra­hydro-4H-chromene-3-carbonitrile

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    In the title mol­ecule, C18H19N3O2, the fused cyclo­hexenone and pyran rings adopt sofa conformations. Inter­molecular N—H⋯N and N—H⋯O hydrogen bonds link mol­ecules into corrugated layers parallel to the bc plane
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