10 research outputs found

    By-products of fruits processing as a source of phytochemicals

    No full text

    An efficient de novo synthesis of 3-deoxythymidine from D-xylose

    No full text
    An efficient stereospecific synthesis of 3-deoxythymidine has been achieved, starting from D-xylose. The key step of the synthesis involved the NBS promoted conversion of 5-O-benzoyl-2,3-di-S-ethyl-2,3-dithio-D-ribose diethyl dithioacetal (4) into the 1-O-acetyl-5-O-benzoyl-2,3-di-S-ethyl-2,3-dithio-b-D-ribofuranose (5), followed by the stereospecific coupling of the intermediate 5 with silylated thymine, in the presence of ethylaluminium dichloride as the catalyst