219 research outputs found

    Atmospheric neutrino oscillations and tau neutrinos in ice

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    The main goal of the IceCube Deep Core Array is to search for neutrinos of astrophysical origins. Atmospheric neutrinos are commonly considered as a background for these searches. We show here that cascade measurements in the Ice Cube Deep Core Array can provide strong evidence for tau neutrino appearance in atmospheric neutrino oscillations. A careful study of these tau neutrinos is crucial, since they constitute an irreducible background for astrophysical neutrino detection.Comment: 5 pages, 3 figure

    Atmospheric neutrinos in ice and measurement of neutrino oscillation parameters

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    The main goal of the IceCube Deep Core Array is to search for neutrinos of astrophysical origins. Atmospheric neutrinos are commonly considered as a background for these searches. We show that the very high statistics atmospheric neutrino data can be used to obtain precise measurements of the main oscillation parameters.Comment: expanded discussion of systematic uncertainties, 8 pages, 4 figure

    Innovare la gestione dei Patrimoni immobiliari Pubblici: La digitalizzazione del processo manutentivo per l’edilizia scolastica.

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    La tesi affronta il tema della creazione delle anagrafiche per la gestione dei patrimoni costruiti, nello specifico quella riferita agli edifici scolastici. Viene proposta una implementazione dell‚Äôattuale struttura anagrafica SNAES ‚ÄúSistema Nazionale delle Anagrafi dell‚ÄôEdilizia Scolastica‚ÄĚ mediante l‚Äôimpiego degli strumenti di modellazione digitale delle informazioni. Rispetto a questo tema la tesi ha per obiettivo quello di collegare il quadro della digitalizzazione delle informazioni, in accordo con le indicazioni nella normativa tecnica nazionale UNI 11337, con il processo di gestione e manutenzione dei patrimoni costruiti esistenti, attraverso l‚Äôutilizzo di strumenti consolidati e che fanno riferimento alla normativa tecnica consensuale (UNI 10874 e UNI 11257). Il lavoro svolto apre la strada a successivi approfondimenti, volti a verificare l‚Äôefficacia e l‚Äôefficienza del modello di gestione elaborato ed il nuovo ruolo attribuito alla committenza, nel quadro tracciato dal D. lgs. n¬į 50 del 2016 ‚Äú Codice Appalti ‚ÄĚ al comma 13 dell‚Äôarticolo 23

    STATIC AND DYNAMIC BEHAVIOUR ASSESSMENT OF THE TRAJAN ARCH BY MEANS OF NEW MONITORING TECHNOLOGIES

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    An effective assessment of the static and dynamic structural behavior of historical monuments requires the development and validation of suitable adaptive structural models using high-quality experimental data acquired with an effectively continuous and distributed monitoring. Furthermore, the adaptive strategy allows an efficient evaluation of the health status and of the evolution along the time of a historical monument, providing relevant information to plan appropriate actions for its long-term preservation. The Trajan Arch in Benevento chosen as a case of study to develop and apply this new adaptive strategy in cultural heritage conservation. The paper, after a description of the innovative monitoring system, based on state-of-the-art mechanical sensors, presents and discusses the results of two tests, comparing the measurements with the predictions of an adaptive structural FEM model developed for the dynamical simulation of the Trajan Arch

    Neural Networks and Photometric Redshifts

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    We present a neural network based approach to the determination of photometric redshift. The method was tested on the Sloan Digital Sky Survey Early Data Release (SDSS-EDR) reaching an accuracy comparable and, in some cases, better than SED template fitting techniques. Different neural networks architecture have been tested and the combination of a Multi Layer Perceptron with 1 hidden layer (22 neurons) operated in a Bayesian framework, with a Self Organizing Map used to estimate the accuracy of the results, turned out to be the most effective. In the best experiment, the implemented network reached an accuracy of 0.020 (interquartile error) in the range 0<zphot<0.3, and of 0.022 in the range 0<zphot<0.5.Comment: 9 pages, 5 figures, 3 table

    Circulating Endothelial Cell Levels Correlate with Treatment Outcomes of Splanchnic Vein Thrombosis in Patients with Chronic Myeloproliferative Neoplasms

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    Circulating endothelial cells (CECs) are viable, apoptotic or necrotic cells, identified by CD 146 surface antigen expression, considered a biomarker of thrombotic risk, given their active role in inflammatory, procoagulant and immune processes of the vascular compartment. Growing evidence establishes that CECs are also involved in the pathogenesis of several hematological and solid malignancies. The primary aim of this study was to verify if CEC levels could predict both the course and treatment responses of splanchnic vein thrombosis (SVT), either in patients affected by myeloproliferative neoplasms (MPNs) or liver disease. Thus, a retrospective multicenter study was performed; fifteen patients receiving anticoagulant oral treatment with vitamin k antagonists (VKA) for SVT were evaluated. Nine patients were affected by MPN, and all of them received cytoreduction in addition to anticoagulant therapy; four of these patients had primary myelofibrosis (PMF) and were treated with ruxolitinib (RUX), and one patient with primary myelofibrosis, two patients with essential thrombocythemia (ET), and two patients with polycythemia vera (PV) were treated with hydroxyurea (HU). Six patients affected by liver diseases (three with liver cirrhosis and three with hepatocellular carcinoma) were included as the control group. CECs were assayed by flow cytometry on peripheral blood at specific time points, for up to six months after enrollment. The CEC levels were related to C-reactive protein (CRP) levels, splenic volume reduction, and thrombus recanalization, mainly in MPN patients. In patients with liver cirrhosis (LC) and hepatocellular carcinoma (HCC), for which the mechanism of SVT development is quite different, the relationship between CEC and SV reduction was absent. In conclusion, the CEC levels showed a significant correlation with the extent of venous thrombosis and endothelial cell damage in myeloproliferative neoplasm patients with splanchnic vein thrombosis. Although preliminary, these results show how monitoring CEC levels during cytoreductive and anticoagulant treatments may be useful to improve SVT outcome in MPN patients

    Organic bioelectronics probing conformational changes in surface confined proteins

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    The study of proteins confined on a surface has attracted a great deal of attention due to its relevance in the development of bio-systems for laboratory and clinical settings. In this respect, organic bio-electronic platforms can be used as tools to achieve a deeper understanding of the processes involving protein interfaces. In this work, biotin-binding proteins have been integrated in two different organic thin-film transistor (TFT) configurations to separately address the changes occurring in the protein-ligand complex morphology and dipole moment. This has been achieved by decoupling the output current change upon binding, taken as the transducing signal, into its component figures of merit. In particular, the threshold voltage is related to the protein dipole moment, while the field-effect mobility is associated with conformational changes occurring in the proteins of the layer when ligand binding occurs. Molecular Dynamics simulations on the whole avidin tetramer in presence and absence of ligands were carried out, to evaluate how the tight interactions with the ligand affect the protein dipole moment and the conformation of the loops surrounding the binding pocket. These simulations allow assembling a rather complete picture of the studied interaction processes and support the interpretation of the experimental results

    Laser Interferometric sensor for Seismic Waves Measurement

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    Laser interferometry is one of the most sensitive methods for small displacement measurement for scientific and industrial applications, whose wide diffusion in very different fields is due not only to the high sensitivity and reliability of laser interferometric techniques, but also to the availability of not expensive optical components and high quality low-cost laser sources. Interferometric techniques have been already successfully applied also to the design and implementation of very sensitive sensors for geophysical applications. In this paper we describe the architecture and the expected theoretical performances of a laser interferometric velocimeter for seismic waves measurement. We analyze and discuss the experimental performances of the interferometric system, comparing the experimental results with the theoretical predictions and with the performances of a state-of the art commercial accelerometer. The results obtained are very encouraging, so that we are upgrading the system in order to measure the local acceleration of the mirrors and beam splitter of the velocimeter using an ad hoc designed monolithic accelerometers for low frequency direct measurement of the seismic noise

    Determinación de contaminantes químicos en el agua de riego en la agricultura periurbana de Córdoba-Argentina

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    El presente trabajo tiene como objetivo determinar la presencia de contaminantes qu√≠micos en los puntos de distribuci√≥n del riego que ba√Īan los cultivos de la Agricultura Periurbana de C√≥rdoba(AUP). La AUP se refiere a pr√°cticas agr√≠colas dentro y alrededor de las ciudades, las cuales compiten por recursos (tierra, agua, energ√≠a y mano de obra) que podr√≠an destinarse tambi√©n a otros fines para satisfacer las necesidades de la poblaci√≥n urbana. El uso intensivo de agroqu√≠micos (fertilizantes, plaguicidas y coadyuvantes) puede dejar residuos en cultivos o aguas subterr√°neas y tener efectos negativos en la salud de los trabajadores agr√≠colas y de la poblaci√≥n en general. El cintur√≥n verde de C√≥rdoba es una zona en la periferia de la ciudad destinada a la actividad frutihort√≠cola. Tiene un √°rea cercana a las 20 mil hect√°reas, la mayor√≠a dentro del Departamento Capital. Alrededor de 260 productores se dedican a hortalizas livianas (verduras de hoja, principalmente, y berenjena, tomate, chaucha y zapallitos en menor medida); y 60 aproximadamente se dedican a hortalizas pesadas (papas, batatas y zanahorias). Cada explotaci√≥n tiene entre 4 y 15 hect√°reas. Mediante la captura de mapas satelitales se realiz√≥ un an√°lisis de los cursos de agua para riego y se agruparon en 5 zonas representativas. Por otra parte, y de acuerdo a datos de presencia de plaguicidas en verdura de hoja correspondientes a los a√Īos 2010 al 2012, los cuales fueron: endolsulf√°n; cipermetrina; deltametrina; permetrina; dimetoato; malation; metamidofos; bifentrina ( de mayor a menor) . Mediante el uso de Diagramas de Pareto se identificaron los contaminantes con mayor frecuencia de aparici√≥n: endolsulf√°n; cipermetrina; deltametrina y permetrina. A trav√©s de la combinaci√≥n de estos datos, se realizaron ensayos de residuos de plaguicidas a muestras de agua provenientes de los sitios seleccionados. Los resultados indican la ausencia de cipermetrina; deltametrina y permetrina y presencia de endosulf√°n en el l√≠mite de detecci√≥n, 0,03 ug/L en todas las zonas. El monitoreo de los cursos de agua y la gesti√≥n de riesgo por zonas en los puntos estrat√©gicos de riego aportan una base para evaluar una variable cr√≠tica como es el agua que impacta sobre los cultivos destinados a consumo humano directo. En este caso la presencia del Endosulf√°n en las aguas usadas para riego cuando en el Decreto 831/93 Anexo II, tabla 5. Niveles gu√≠a de calidad de agua para irrigaci√≥n no est√° contemplado puede ser √ļtil como un alerta temprano del riesgo de exposici√≥n a √©ste y otros contaminantes qu√≠micos. Los mapas obtenidos en este estudio tambi√©n podr√°n brindar aportes para gestionar el riesgo del impacto vinculado a la presencia de otros contaminantes qu√≠micos en las temporadas de cosecha.Fil: Faillaci, Silvina Mabel. Universidad Nacional de C√≥rdoba. Facultad de Ciencias Exactas, F√≠sicas y Naturales; Argentina.Fil: Faillaci, Silvina Mabel. Secretar√≠a de Ciencia y Tecnolog√≠a (SeCyT). Instituto de Ciencia y Tecnolog√≠a de los Alimentos C√≥rdoba; Argentina.Fil: Faillaci, Silvina Mabel. Secretar√≠a de Ciencia y Tecnolog√≠a (SeCyT). Instituto Superior de Estudios Ambientales; Argentina.Fil: Nassetta, Mirtha. Universidad Nacional de C√≥rdoba. Facultad de Ciencias Exactas; F√≠sicas y Naturales; Argentina.Fil: Nassetta, Mirtha. Secretar√≠a de Ciencia y Tecnolog√≠a (SeCyT). Instituto Superior de Estudios Ambientales; Argentina.Fil: Giordano, Jes√ļs. Universidad Nacional de C√≥rdoba. Facultad de Ciencias Exactas; F√≠sicas y Naturales; Argentina.Fil: Giordano, Jes√ļs. Secretar√≠a de Ciencia y Tecnolog√≠a (SeCyT). Instituto de Ciencia y Tecnolog√≠a de los Alimentos C√≥rdoba; Argentina.Fil: L√≥pez, Abel Gerardo. Universidad Nacional de C√≥rdoba. Facultad de Ciencias Exactas; F√≠sicas y Naturales; Argentina.Fil: L√≥pez, Abel Gerardo. Secretar√≠a de Ciencia y Tecnolog√≠a (SeCyT). Instituto de Ciencia y Tecnolog√≠a de los Alimentos C√≥rdoba; Argentina.Fil: Miropolsky, Ariel. Universidad Nacional de C√≥rdoba. Facultad de Ciencias Exactas; F√≠sicas y Naturales; Argentina.Fil: Miropolsky, Ariel. Secretar√≠a de Ciencia y Tecnolog√≠a (SeCyT). Instituto de Ciencia y Tecnolog√≠a de los Alimentos C√≥rdoba; Argentina.Alimentos y Bebida
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