1,510 research outputs found

    Las relaciones económicas del Ecuador y Colombia

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    Escuela de m√ļsica Cadenza ‚Äď renovaci√≥n urbana

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    Art√≠culo de investigaci√≥nEste documento pone en materia la Renovaci√≥n Urbana como t√°ctica para la revitalizaci√≥n de una zona del centro de Bogot√° (Colombia), espec√≠ficamente en una de las secciones de la calle del Bronx, Ubicado entre las calles 9 y 10 y las carreras 15 y 15¬™ en el sector de los M√°rtires y proporciona una idea de c√≥mo abordar un problema de desarticulaci√≥n en un lugar degradado por sus condiciones.1. RESUMEN 2. INTRODUCCION 3. METODOLOGIA 4. RESULTADOS 5. DISCUSI√ďN 6. CONCLUCIONES 7. REFERENCIAS 8. BIBLIOGRAF√ćA 9. TABLA DE FIGURAS 10. ANEXOSPregradoArquitect

    Optimal experimental design for process optimization with stochastic binary outcomes

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    Effective control of the end-use properties in order to guarantee product quality is of paramount importance. This is especially valuable for products such as medicament, polymers and nanomaterials. There are plenty of innovative processes whose principles of operation are unknown and for which is not possible to develop reliable models due to time and cost. Despite this, it is important to know the optimum operating zone where the process should work to ensure that the end product meets the required properties. To address this issue, a run-to-run optimization approach is proposed to find the reduced region of operation which guarantees obtaining end-use properties with high probability when a first-principles model for the batch process is not available a priori. In order to evaluate the effectiveness of the methodology to find optimal policies for runs involving stochastic binary outcomes, the well-known example of the emulsion polymerization of styrene has been addressed. Results obtained demonstrated that the proposed method is a powerful tool for optimal design of experiments aiming to guarantee end-use product properties.Sociedad Argentina de Informática e Investigación Operativa (SADIO

    Model-based run-to-run optimization for process development

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    Research and development of new processes is a fundamental part of any innovative industry. For process engineers, finding optimal operating conditions for new processes from the early stages is a main issue, since it improves economic viability, helps others areas of R&D by avoiding product bottlenecks and shortens the time-to-market period. Model-based optimization strategies are helpful in doing so, but imperfect models with parametric or structural errors can lead to suboptimal operating conditions. In this work, a methodology that uses probabilistic tendency models that are constantly updated through experimental feedback is proposed in order to rapidly and efficiently find improved operating conditions. Characterization of the uncertainty is used to make safe predictions even with scarce data, which is typical in this early stage of process development. The methodology is tested with an example from the traditional innovative pharmaceutical industry.Fil: Luna, Mart√≠n Francisco. Consejo Nacional de Investigaciones Cient√≠ficas y T√©cnicas. Centro Cient√≠fico Tecnol√≥gico Conicet - Santa Fe. Instituto de Desarrollo y Dise√Īo. Universidad Tecnol√≥gica Nacional. Facultad Regional Santa Fe. Instituto de Desarrollo y Dise√Īo; ArgentinaFil: Mart√≠nez, Ernesto Carlos. Consejo Nacional de Investigaciones Cient√≠ficas y T√©cnicas. Centro Cient√≠fico Tecnol√≥gico Conicet - Santa Fe. Instituto de Desarrollo y Dise√Īo. Universidad Tecnol√≥gica Nacional. Facultad Regional Santa Fe. Instituto de Desarrollo y Dise√Īo; Argentin

    Optimal experimental design for process optimization with stochastic binary outcomes

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    Effective control of the end-use properties in order to guarantee product quality is of paramount importance. This is especially valuable for products such as medicament, polymers and nanomaterials. There are plenty of innovative processes whose principles of operation are unknown and for which is not possible to develop reliable models due to time and cost. Despite this, it is important to know the optimum operating zone where the process should work to ensure that the end product meets the required properties. To address this issue, a run-to-run optimization approach is proposed to find the reduced region of operation which guarantees obtaining end-use properties with high probability when a first-principles model for the batch process is not available a priori. In order to evaluate the effectiveness of the methodology to find optimal policies for runs involving stochastic binary outcomes, the well-known example of the emulsion polymerization of styrene has been addressed. Results obtained demonstrated that the proposed method is a powerful tool for optimal design of experiments aiming to guarantee end-use product properties.Sociedad Argentina de Informática e Investigación Operativa (SADIO

    Bayesian optimization of crystallization processes to guarantee end-use product properties

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    For pharmaceutical solid products, the issue of reproducibly obtaining their desired end-use properties depending on crystal size and form is the main problem to be addressed and solved in process development. Lacking a reliable first-principles model of a crystallization process, a Bayesian optimization algorithm is proposed. On this basis, a short sequence of experimental runs for pinpointing operating conditions that maximize the probability of successfully complying with end-use product properties is defined. Bayesian optimization can take advantage of the full information provided by the sequence of experiments made using a probabilistic model of the probability of success based on a one-class classification method. The proposed algorithm's performance is tested in silico using the crystallization and formulation of an API product where success is about fulfilling a dissolution profile as required by the FDA. Results obtained demonstrate that the sequence of generated experiments allows pinpointing operating conditions for reproducible quality.Fil: Luna, Mart√≠n Francisco. Consejo Nacional de Investigaciones Cient√≠ficas y T√©cnicas. Centro Cient√≠fico Tecnol√≥gico Conicet - Santa Fe. Instituto de Desarrollo y Dise√Īo. Universidad Tecnol√≥gica Nacional. Facultad Regional Santa Fe. Instituto de Desarrollo y Dise√Īo; ArgentinaFil: Mart√≠nez, Ernesto Carlos. Consejo Nacional de Investigaciones Cient√≠ficas y T√©cnicas. Centro Cient√≠fico Tecnol√≥gico Conicet - Santa Fe. Instituto de Desarrollo y Dise√Īo. Universidad Tecnol√≥gica Nacional. Facultad Regional Santa Fe. Instituto de Desarrollo y Dise√Īo; Argentin

    Uma contribuição ao estudo de VTCDs aplicado a equipamentos eletronicos alimentados por conversor CA-CC

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    Orientador: Sigmar Maurer DeckmannDisserta√ß√£o (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computa√ß√£oResumo: Este trabalho visa contribuir para os estudos de Varia√ß√Ķes de Tens√£o de Curta Dura√ß√£o (VTCDs) buscando relacionar tais dist√ļrbios com o real impacto que causam em uma importante fam√≠lia de cargas, s√£o os equipamentos eletr√īnicos alimentados por conversores CA-CC. Esta correla√ß√£o entre causa e efeito ainda √© um dos pontos menos estudados no √Ęmbito da Qualidade da Energia El√©trica (QEE). Considerando o cen√°rio nacional e internacional, inicialmente ser√£o apresentadas as principais normas aplic√°veis √†s VTCDs, caracteriza√ß√£o de eventos e verifica√ß√£o de impacto sobre as cargas procurando sempre fazer uma an√°lise cr√≠tica, mostrar suas converg√™ncias, particularidades e defici√™ncias. O estudo sobre a fam√≠lia de cargas escolhida ter√° como objetivo verificar os par√Ęmetros mais relevantes frente √†s VTCDs, desenvolver t√©cnicas para extra√ß√£o desse par√Ęmetros, que possam ser utilizadas pelos fabricantes dos equipamentos, pelas concession√°rias de energia el√©trica e pelos consumidores finais desses equipamentos. Finalmente, ser√° apresentada uma metodologia para avalia√ß√£o de impacto de VTCDs, baseado no comportamento das cargas estudadas, podendo ser aplicada a um equipamento isolado, como tamb√©m a um processo industrial mais complexoAbstract: This dissertation presents a contribution to the study of voltage sags and swells and their real impact on an important group of loads constituted by electronic equipment supplied by AC-DC converters. The establishment of a relationship between cause and effect has still not being focused in the study of voltage sags and swells. Initially, this work presents a critical analysis of the main International and Brazilian standards about characterization and impact estimation of voltage sags and swells, demonstrating the convergence, singularity and deficiency of each one. Then, the study of the proposed load group aims to find and demonstrate the most important parameters related to voltage sags and swells, and to describe some techniques to obtain these parameters, which could be used by electronic manufacturers, utilities and equipment users. Finally, a special methodology is proposed to evaluate the impact of voltage sags and swells, which is based on based on the behavior of the loads under consideration. The proposed methodology can be applied on single electronic equipment or also on a general system, such as industrial plantsMestradoMestre em Engenharia El√©tric

    Conservación de la naturaleza: crítica a la estrategia contemporánea para la conservación de las especies

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    La conservaci√≥n de la naturaleza es un tema de inter√©s actual; sin embargo, este planteamiento tiene diversos significados en el mundo contempor√°neo, tanto en su sentido filos√≥fico como cient√≠fico. No obstante esta diversidad de visiones, la propuesta conservacionista que hace la Uni√≥n Mundial para la Naturaleza (IUCN) resulta la de mayor aceptaci√≥n e influencia. Dentro de este planteamiento, ocupa una posici√≥n central la conservaci√≥n de especies, tanto animales como vegetales; y de manera especial, la conservaci√≥n biol√≥gica de especies. En esta tesis se analiza el pensamiento contempor√°neo sobre la conservaci√≥n de la naturaleza, aplicando un enfoque basado en la historia y la sociolog√≠a de las comunidades cient√≠ficas desde una perspectiva kuhniana. La elecci√≥n de la perspectiva kuhniana permite revisar cr√≠ticamente la estrategia contempor√°nea para la conservaci√≥n de la naturaleza y, con ello, poder determinar nuevos problemas para la investigaci√≥n en biolog√≠a de la conservaci√≥n y para la formulaci√≥n de un nuevo paradigma conservacionista. Adem√°s, posibilita situarse en una posici√≥n cr√≠tica sobre la historiograf√≠a de las ideas cient√≠ficas, particularmente, para cuestionar la idea de naturaleza como una construcci√≥n hist√≥rico-social. En este sentido, se indaga el interior de una comunidad expertos, a la que pertenece el autor de la tesis, que se ha integrado con el prop√≥sito de asegurar la conservaci√≥n de las especies, en este caso particular, de primates. De este modo se plantean problemas desde la perspectiva de la sociolog√≠a de la ciencia. De ah√≠ que, m√°s all√° de los m√©ritos de esta reflexi√≥n hist√≥rica y filos√≥fica, el resultado de este ejercicio es un conjunto de preguntas, que desaf√≠an el paradigma contempor√°neo de la conservaci√≥n de la naturaleza. ¬ŅHa cumplido su promesa el paradigma conservacionista de la IUCN? ¬ŅSe ha logrado detener o revertir la extinci√≥n masiva de especies? ¬ŅHa sido suspendida la transformaci√≥n de los paisajes naturales del mundo? ¬ŅHemos creado las condiciones para el desarrollo sostenible en las regiones de mayor riqueza bi√≥tica y, al mismo tiempo, de pobreza humana? ¬ŅDeberemos mantener esta visi√≥n paradigm√°tica para la conservaci√≥n de la naturaleza

    Growing Specialty Coffee: Economic security and environmental sustainability in global coffee systems

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    The Gund Institute has partnered with the Agroecology & Livelihoods Collaborative to create a more sustainable and just global coffee sector. Gund Fellows used this research brief to leverage our networks and engage NGOs such as The Specialty Coffee Association, funders, and companies in early discussions about how to address systemic inequity across the coffee value chain

    SPIMED, defendiendo la ciencia joven

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