2,159 research outputs found

    Kinetics of mobilization of neutrophils and their marrow pool in protein-calorie deficiency

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    Migration of marrow neutrophils under basal conditions and their mobilization, following subcutaneous implantation of cover slips, were investigated in groups of protein-deficient rats, using 3HTdR with sequential autoradiography of the peripheral blood smears. Animals fed a protein-rich diet served as controls. The pattern of appearance of labeled neutrophils in the blood was identical in the two groups under basal conditions. However, a higher percentag of labeled neutrophils appeared earlier in the blood following cover slip implantation in the deficient rats as compared to controls. The inflammatory exudate on the cover slips was low throughout the period of observation in deficient animals, with a delay in the appearance of monocytes. A pool of mature neutrophils resides in the bone marrow. It is proposed that in PCM there is atrophy of all neutrophil compartments, including that of the marrow pool, associated with a proportionate reduction in the efflux of cells from one compartment to another. This proportionate reduction in efflux would explain the normal kinetics of migration of neutrophils under basal conditions in the deficient rats in spite of a reduction in the marrow pool. On the other hand, in cover slip-implanted deficient rats, appearance of larger numbers of labeled neutrophils in the blood is attributed to a reduction in size of the marrow pool. This hypothesis is substantiated by the experiments in protein-deficient monkeys in which estimation of the marrow pool of neutrophils revealed a marked reduction in the deficient animals. It is further proposed that a diminuation of the marrow pool of neutrophils and retarded mobilization of cells at the site of inflammation are important mechanism responsible for the increased susceptibility of the malnourished host to infections

    Maximum temperature for an Ideal Gas of U^(1)\hat U(1) Kac-Moody Fermions

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    A lagrangian for gauge fields coupled to fermions with the Kac-Moody group as its gauge group yields, for the pure fermions sector, an ideal gas of Kac-Moody fermions. The canonical partition function for the U^(1)\hat U(1) case is shown to have a maximum temperature kTM=λ/πkT_{M} = |\lambda| /\pi, where λ\lambda is the coupling of the super charge operator G0G_0 to the fermions. This result is similar to the case of strings but unlike strings the result is obtained from a well-defined lagrangian.Comment: Needs subeqnarray.sty; To be published in Phys. Rev. D, Dec 15, 1995. Some typographical errors have been corrected in the revised versio

    Incidence of Removable Partial Denture Types in Eastern Wisconsin

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    Aim: This study was designed to investigate patterns of tooth loss in patients receiving removable partial dentures. Materials and Method: A point and shoot digital camera was used to collect 1502 digital images of cases at 5 dental laboratories in the eastern portion of the state of Wisconsin. Any case presenting to one the dental laboratories requesting a RPD was included. Two photographs were taken of each case. The first photograph was taken immediately upon arrival to the lab while the second photograph was taken immediately prior its first departure. A calibrated investigator analyzed all the photographs for Kennedy classification, type of RPD, major connectors, and other details Results: Kennedy class I was the most commonly constructed RPDs at a frequency of 41%. In the maxilla, class III RPDs were the most frequently fabricated while class I remained the most common RPD in the mandible. 73% of the RPDs used metal frameworks, while the remaining 27% of RPDs used acrylic or flexible frameworks. The horseshoe major connector was the most common maxillary major connector while in the mandible it was the lingual plate. Conclusions: Kennedy class I RPDs are still the most common mandibular RPD. However, the class III RPD is the most common maxillary RPD. 27% of all RPDs in this region utilized simple non-metallic frameworks which rarely met established design criteria. These numbers indicate a varying quality level of prosthodontic procedures provided in this region