12 research outputs found

    Spatial Span Backward and Digit Span Backward scores with age.

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    <p>Spaghetti plots of individual participant change in Spatial Span Backward and Digit Span Backward scores with age (years). Females are plotted in red and males in blue. For each measure, an assumption-free general additive mixed model as a function of age was fitted to accurately describe group-level changes across the age range.</p

    FA or MD and change in visuospatial working memory.

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    <p>Scatterplots showing linear relationships between change in FA or MD and change in visuospatial working memory. The plots show FA and MD in TOIs, plotted as z-transformed change values. For Spatial Span Backward scores age, sex and interval are regressed out, and for each TOI age, sex, interval and motion at both time points are regressed out. The partial correlation (r) between change in FA and MD in specific white matter tracts and change in Spatial Span Backward scores, controlling for age, sex, interval and motion at both time points are presented in each plot. The color-coded scatterplots represent the color of each specific white matter tract. Color codes refer to: Yellow: Inferior fronto-occipital fasciculus (IFOF), Red: Forceps major (FMaj), Light blue: Inferior longitudinal fasciculus (ILF) and Green: Uncinate fasciculus (UF). R = right.</p

    List of SNPs with observed association p-value being less than 1.00E-05.

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    <p>Chromosomal position is specified in Build 36 (hg18). OR refers to odds ratio and 95%CI refers to 95% confidence interval. <i>TRIM36</i> refers to tripartite motif containing 36 gene. <i>ZBTB16</i> refers to zinc finger and BTB domain containing 16 gene.</p><p>List of SNPs with observed association p-value being less than 1.00E-05.</p

    Protein-protein interaction network build from proteins encoded in associated intervals.

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    <p>The colored, full circles represent proteins encoded in associated intervals (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0122501#pone.0122501.s002" target="_blank">S2 Table</a>). The smaller, grey circles represent interactors of indirect connections. Functionally, the DAPPLE-constructed diagram can be divided into two main groups: group “A” mostly involved in the regulation of gene expression and inflammation; and group “B” mostly involved in cell adhesion.</p
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