32 research outputs found

    Consumer intention to use smartphone for mobile shopping

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    The purpose of this study is to identify the determinants to use the mobile phone to make purchases. The study involved a total of 210 respondents approached in a public higher learning institution in Federal Territory of Labuan, Malaysia. This study applies convenience sampling technique to ensure researcher to monitor the participation of the sample. They were chosen to identify the intention to use smartphones for mobile shopping among young adults. The concept of using smartphones for mobile shopping was explained to the respondents to ensure full understanding in order to obtain best result. Multiple regression analysis asserted that Perceived Usefulness (PU), Perceived Enjoyment (PE), Perceived Ease of Use (PEOU), and Satisfaction (SAT) influence the Intention to use (INT). The results could help online retailers in improving their marketing platform and to understand more of their customers' needs and wants

    Metabolomics study of CHO cell cultures

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    Ph.DDOCTOR OF PHILOSOPH

    Optimal design of two-sided CUSUM schemes

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    An optimal CUSUM chart is commonly defined as one with a fixed in control average run length (ARL) and the smallest ARL for a specified shift Δ in the mean. As the run length distribution is usually positively skewed, median run length (MRL) is a more reasonable measure of location than the mean given by ARL. As such it is more reasonable to define the optimal CUSUM in terms of MRL. The optimal CUSUM schemes in terms of ARL and MRL are obtained in the case when the observations have a normal or exponential distribution. It is found that the parameter (k, h) of the optimal CUSUM in terms of ARL and that of the optimal CUSUM in terms of MRL are fairly different

    Biomimetic processing of bioactive interface on silicon substrates

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    To facilitate the implantation of silicon-based devices in vivo, the presence of a biocompatible and bioactive coating is noted to be an essential factor. The objective of this present work is therefore to explore a relatively simple and low cost process to induce the formation of bioactive apatite on silicon. The formation of apatite on silicon was carried out by a biomimetic approach on two orientations of silicon wafer, namely (100) and (111). The samples are functionalized by chemical etching, followed by incubation in a simulated body fluid. Scanning electron microscopy, energy dispersive X-ray analysis, X-ray diffraction analysis, and X-ray photoelectron spectroscopy were carried out. It was found that the growth of apatite is dependent on the orientation of the silicon wafer. Cell culturing experiment further verified the biological performance of the apatite-coated silicon samples

    Evolution of surface roughness during metal silicides phase transformation

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    This study monitors systematically the evolution of surface roughness during metal (Ti, Co, and Ni) silicides phase transformation and coupling to other physical parameters. During metal/silicon reaction film surface roughness evolves due to the effect of nucleation and growth of metal silicides and is sensitive to different processing conditions. In general, surface roughness increases as new phases are formed and decreases during grain growth. The difference in roughness between processes indicates whether a process is more inferior for new phase formation. The correlation of surface roughness towards sheet resistance, film thickness, and phase transformation are found to be independent of film thickness in C49-to-C54 TiSi2 polymorphic transformation but not for Co and Ni silicides. Any abnormalities from the trend indicate that the film is experiencing a physical degradation.Published versio

    Aberrant Presentation of Self-Lipids by Autoimmune B Cells Depletes Peripheral iNKT Cells

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    Summary: Invariant natural killer T (iNKT) cells provide cognate help via CD1d to lipid antigen-presenting B cells for antibody production, but whether B cells reciprocally regulate iNKT cells remains largely unexplored. Here, we found peripheral, but not thymic, iNKT cells to be numerically reduced in autoimmune mice lacking Fas specifically in B cells. The residual iNKT cells were antigenically overstimulated, had altered cytokine production, and manifested enhanced proliferation and apoptosis. B cell-specific ablation of CD1d ameliorated these iNKT defects, suggesting that inappropriate presentation of CD1d-restricted self-lipids by autoimmune B cell-depleted peripheral iNKT cells. CD1d+ autoimmune B cells have reduced α-galactosidase A expression and, as revealed by lipidomic profiling, altered lipidome with aberrant accumulation of certain self-lipids and reduction of others. These findings unveil a critical link between autoimmunity, B cell lipidome, and the maintenance of peripheral iNKT cells and highlight an essential homeostatic function of B cells beyond antibody production. : Invariant natural killer T (iNKT) cells help B cell antibody production, but how B cells reciprocally modulate iNKT cell responses is less clear. Tan et al. now identify inappropriate presentation of CD1d-restricted self-lipids by autoimmune B cells as a primary mechanism leading to iNKT cell hyperactivation, proliferation, and apoptosis in autoimmune mice. Autoimmune B cells are shown to have an altered lipidome, suggesting that this is linked to iNKT homeostasis

    Silicide formation from laser thermal processing of Ti/Co bilayers

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    A bilayered CoTi silicide structure consisting of an amorphous CoTi silicide and a highly textured CoTi silicide was found after pulsed excimer laser annealing of titanium/cobalt/silicon stack at high fluence of 0.6 J/cm2. The highly textured CoTi silicide is monocrystalline and fully coherent with the Si(111) plane of the substrate but has a large amount of microstructural defects. The constitutional supercooling phenomenon is the solidification mechanism responsible for the highly textured CoTi silicide. The incomplete crystallization shown by the presence of the amorphous CoTi silicide is attributed to a high concentration of titanium impurity.Published versio
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