908 research outputs found

    The Benefits of Exposure to Animals for Persons with Dementia: A Literature Review

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    This literature review was performed to assess the current standing of the use of animals as a therapeutic agent for individuals suffering from dementia. This area of study is currently broad; therefore the intent of reviewing the current literature was to establish what has been studied at this point in time and to recommend future research directions in the field. The literature search was performed on three academic search sites (PsycINFO, PubMed, and AgeLine) using four search terms (ÔÇťPet therapy AlzheimerÔÇÖs,ÔÇŁ ÔÇťPet therapy dementia,ÔÇŁ ÔÇťAnimal therapy AlzheimerÔÇÖs,ÔÇŁ ÔÇťAnimal therapy dementiaÔÇŁ); search results were verified by having a second researcher independently conduct the literature search using the same criteria used by the author. A total of 26 studies meeting inclusion criteria were reviewed. The general findings of this review show that individuals suffering from dementia who are exposed to animals tend to show improvements in measured outcomes (including behavioral, social, and physiological measures). Based on these findings, it is recommended that future studies examining the impact of interactions between persons with dementia and animals are warranted. However it is recommended that future studies should be done with a more focused intent, should include larger numbers of participants, and should make use of more standardized assessments instruments so the benefits of exposure to animals can be more definitively established

    Critical process parameter identification using the ambr15(tm) for process characterization

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    Process characterization is a critical phase in the development of a commercial process for biotherapeutic production. Knowing the critical quality attributes of your molecule prior to beginning process development and/or characterization is imperative when using a quality by design (QbD) approach. Here we use a (QbD) approach for the characterization of a fed-batch process using an NSO cell line to express an IgG. For this molecule, the glycosylation profile, and in particular, the total fucosylation was identified as a critical quality attribute. After performing a primary hazard analysis, several process inputs were determined to potentially have an impact on this critical quality attribute. These parameters were then studied in a screening DoE using the ambr15Ôäó to model the first and second order effects for each parameter on both the critical quality attributes and process performance. Of the 9 parameters studied, 5 were determined to have a statistically significant effect on the fucosylation of the molecule. In addition, 6 parameters were identified to have a significant impact on process performance. Through process modeling using JMP, a design space was determined for further studies to determine the proven acceptable range (PAR) for each parameter using the 10L, qualified scale down model. An example of the predicted PAR for pH and the timing of the temp shift can be seen in figure 1. Following the 10L studies, a PAR was determined for each parameter and compared with the predicted PAR from ambr. Here we demonstrate the feasibility to use the ambr15Ôäó as a tool for key and even critical process parameter identification to reduce timelines for process characterization

    An Exploratory Study of Classroom Diversity and Cultural Competency

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    This exploratory study compares the effectiveness of multicultural training across two classrooms of counselors-in-training at a predominately white institutionÔÇöone which was homogenous in class composition; the other which was diverse in class composition. Results indicated that there was a statistically significant difference between classrooms and that individual students demonstrated statistically significant change in perceived multicultural competence. Such findings highlight the need for ongoing research that explores influence of classroom composition on cultural competency training for counseling graduate students

    Empirical approaches to improving the use of DNA in crime scene investigative practice

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    At the beginning of the 21st century, rural policy remains one of the most important areas of public policy; huge financial and human resources are devoted to the implementation of this policy measures. The aim of the article is to provide holistic evaluation of the goals, means and key achievements of Lithuanian agricultural policy and to identify possible areas and ways of improvement. The diversity of agricultural policy measures applied in Lithuania after the restoration of independence in 1990 and achievements of the policy are analysed on the basis of new approach ÔÇô the theory of qualitative structures. The study explores how policy measures to accelerate the process of industrialization in Lithuanian agriculture after the privatization of kolkhozes and sovkhozes have encouraged and supported private farms to implement extensive growth, intensification, specialization, risk management, collaboration and innovation production strategies, and what results they have achieved.XXI a. prad┼żioje kaimo politika i┼ílieka viena i┼í svarbiausi┼│ vie┼íosios politikos sri─Źi┼│. ┼áios politikos priemon─Śms diegti skiriama labai daug finansini┼│ ir ┼żmogi┼ík┼│j┼│ i┼ítekli┼│. Straipsnio tikslas ÔÇô holisti┼íkai ─»vertinti Lietuvos ┼żem─Śs ┼źkio politikos tikslus, priemones ir pasiekimus, identifikuoti galimas tobulinimo kryptis. ┼Żem─Śs ┼źkio politikos priemoni┼│, taikyt┼│ Lietuvoje po nepriklausomyb─Śs atgavimo 1990 m., ─»vairov─Ś ir pasiekimai analizuojami remiantis kokybini┼│ strukt┼źr┼│ analiz─Śs metodu. Aptariama, kaip politikos priemon─Śmis, siekiant paspartinti industrializacijos proces─ů Lietuvos ┼żem─Śs ┼źkyje, ┼źkininkai buvo skatinami panaudoti ┼íi┼│ priemoni┼│ kokybin─Śs strukt┼źros galimybes, kad b┼źt┼│ ─»gyvendinamos ekstensyvaus augimo, intensifikacijos, specializacijos, rizikos valdymo, bendradarbiavimo ir inovacij┼│ strategijos
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