88 research outputs found

    AVALIA√á√ÉO DE DOR NO ADULTO CR√ćTICO EM USO DE VENTILA√á√ÉO MEC√āNICA: REVIS√ÉO DE LITERATURA

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    A dor √© o quinto sinal vital e assim como os demais deve ser rotineiramente avaliada. Em pacientes que n√£o conseguem verbalizar, h√° o entrave para a avalia√ß√£o da dor atrav√©s do uso de escalas. O objetivo deste trabalho √© identificar na literatura o uso de instrumento de monitoramento da dor em adultos cr√≠ticos submetidos a ventila√ß√£o mec√Ęnica em unidades de terapia intensiva. Trata-se de uma revis√£o integrativa de literatura, com a seguinte quest√£o norteadora ‚ÄúQual os instrumentos utilizados pela equipe de enfermagem para avaliar a dor de adultos em uso de ventila√ß√£o mec√Ęnica em unidades de terapia intensiva?‚ÄĚ. Os artigos foram buscados nas bases de dados PUBMED, MEDLINE, LILACS e SCIELO com os descritores e operadores booleanos Medi√ß√£o da dor AND Respira√ß√£o Artificial. Os crit√©rios de inclus√£o foram ser dos √ļltimos 5 anos, em ingl√™s, espanhol ou portugu√™s e responder ao objetivo ou pergunta da pesquisa. Foram exclu√≠dos artigos de revis√£o. Oito artigos foram identificados, com 75% dos estudos utilizando a escala CPOT para avaliar a dor nos pacientes. √Č um instrumento de f√°cil aplica√ß√£o que avalia 4 indicadores de dor, indo de dor nenhuma at√© dor m√°xima. Enfermeiros reconhecem a import√Ęncia da avalia√ß√£o e manejo da dor de pacientes em ventila√ß√£o mec√Ęnica como fator humanizador do cuidado, al√©m de permitir o planejamento da assist√™ncia de enfermagem adequadahttps://revistaft.com.br/avaliacao-de-dor-no-adulto-critico-em-uso-de-ventilacao-mecanica-revisao-de-literatura

    Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial

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    Background: Sparsentan is a novel, non-immunosuppressive, single-molecule, dual endothelin and angiotensin receptor antagonist being examined in an ongoing phase 3 trial in adults with IgA nephropathy. We report the prespecified interim analysis of the primary proteinuria efficacy endpoint, and safety. Methods: PROTECT is an international, randomised, double-blind, active-controlled study, being conducted in 134 clinical practice sites in 18 countries. The study examines sparsentan versus irbesartan in adults (aged ‚Č•18 years) with biopsy-proven IgA nephropathy and proteinuria of 1¬∑0 g/day or higher despite maximised renin-angiotensin system inhibitor treatment for at least 12 weeks. Participants were randomly assigned in a 1:1 ratio to receive sparsentan 400 mg once daily or irbesartan 300 mg once daily, stratified by estimated glomerular filtration rate at screening (30 to 1¬∑75 g/day). The primary efficacy endpoint was change from baseline to week 36 in urine protein-creatinine ratio based on a 24-h urine sample, assessed using mixed model repeated measures. Treatment-emergent adverse events (TEAEs) were safety endpoints. All endpoints were examined in all participants who received at least one dose of randomised treatment. The study is ongoing and is registered with ClinicalTrials.gov, NCT03762850. Findings: Between Dec 20, 2018, and May 26, 2021, 404 participants were randomly assigned to sparsentan (n=202) or irbesartan (n=202) and received treatment. At week 36, the geometric least squares mean percent change from baseline in urine protein-creatinine ratio was statistically significantly greater in the sparsentan group (-49¬∑8%) than the irbesartan group (-15¬∑1%), resulting in a between-group relative reduction of 41% (least squares mean ratio=0¬∑59; 95% CI 0¬∑51-0¬∑69; p<0¬∑0001). TEAEs with sparsentan were similar to irbesartan. There were no cases of severe oedema, heart failure, hepatotoxicity, or oedema-related discontinuations. Bodyweight changes from baseline were not different between the sparsentan and irbesartan groups. Interpretation: Once-daily treatment with sparsentan produced meaningful reduction in proteinuria compared with irbesartan in adults with IgA nephropathy. Safety of sparsentan was similar to irbesartan. Future analyses after completion of the 2-year double-blind period will show whether these beneficial effects translate into a long-term nephroprotective potential of sparsentan. Funding: Travere Therapeutics

    FEN√ĒMENOS PSICOSSOM√ĀTICOS E OS SINAIS NO PROFESSOR UNIVERSIT√ĀRIO

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    The academic environment is no stranger to suffering. It is known that mental disorders are present in almost all activities and contexts in which human beings act. Thus, in the university context, the vast majority of faculty members experience a high degree of academic stress. The aim of this study was to evaluate psychosomatic phenomena and their signs in university professors. This is a cross-sectional, descriptive observational study of quantitative approach, consisting of 45 of the higher education courses of a private university in S√£o Lu√≠s do Maranh√£o. The data collection instrument was a questionnaire with sociodemographic data and test scale: SQR 20. The results pointed out that most of them were female (59.1%), aged between 26 and 50 years old, married (52.3%), with income between five or more minimum wages (59.1%), most of them with a master's degree (50%), working in the health area (50%), depressed and nervous moods were the most prevalent (62.2%), headaches were most prevalent (48.9%), getting tired easily (42.2%), loss of interest in things (20%), and psychological suffering was most prevalent in teachers who had been working for more than 4 years. We emphasize that due to the importance of the theme, there is a scarcity of scientific studies that explore this subject. Thus, it is necessary that research be done to understand teachers, since they are susceptible to the development of psychosomatic disorders. &nbsp;El entorno acad√©mico no es ajeno al sufrimiento. Se sabe que los trastornos mentales est√°n presentes en casi todas las actividades y contextos en los que act√ļa el ser humano. As√≠, en el contexto universitario, la gran mayor√≠a del profesorado, experimenta un alto grado de estr√©s acad√©mico. El objetivo de este estudio fue evaluar los fen√≥menos psicosom√°ticos y sus signos en profesores universitarios. Se trata de un estudio observacional descriptivo transversal, de abordaje cuantitativo, compuesto por 45 de los cursos de ense√Īanza superior de una universidad privada de S√£o Lu√≠s do Maranh√£o. El instrumento de recolecci√≥n de datos fue un cuestionario con datos sociodemogr√°ficos y escala de prueba: SQR 20. Los resultados se√Īalaron que la mayor√≠a era del sexo femenino (59,1%), con edades entre 26 y 50 a√Īos, casados (52,3%), con renta entre cinco o m√°s salarios m√≠nimos (59,1%), la mayor√≠a con maestr√≠a m√°xima (50%), activos en el √°rea de salud (50%), el estado de √°nimo depresivo y nervioso era el m√°s frecuente (62,2%), los dolores de cabeza eran m√°s frecuentes (48,9%), cansarse con facilidad (42,2%), p√©rdida de inter√©s por las cosas (20%), el sufrimiento psicol√≥gico era prevalente en los profesores que llevaban m√°s de 4 a√Īos trabajando. Destacamos que debido a la importancia del tema, hay escasez de estudios cient√≠ficos que exploren esta tem√°tica. Por lo tanto, es necesario realizar investigaciones para comprender a los profesores, ya que son susceptibles al desarrollo de trastornos psicosom√°ticos.O ambiente acad√™mico n√£o √© estranho ao sofrimento. Sabe-se que as doen√ßas mentais est√£o presentes em quase todas as atividades e contextos em que o ser humano atua. Assim, no contexto universit√°rio, a grande maioria do corpo docente, vivencia um elevado grau de estresse acad√™mico. O objetivo deste estudo foi avaliar os fen√īmenos psicossom√°ticos e seus sinais nos professores universit√°rios. Trata-se de um estudo observacional transversal, descritivo de abordagem quantitativa, constitu√≠do por 45 dos cursos de ensino superior de uma universidade privada em S√£o Lu√≠s do Maranh√£o. O instrumento de coleta de dados foi um question√°rio com dados sociodemogr√°ficos e escala de teste: SQR 20. Os resultados apontaram que a maioria do sexo feminino (59,1%),com idades entre 26 a 50 anos ,casadas (52,3%), com renda entre &nbsp;cinco ou mais sal√°rios m√≠nimos (59,1%), maior parte com titula√ß√£o m√°xima o mestrado (50%), atuantes na √°rea da sa√ļde (50%), humor depressivo , nervoso foi o mais frequente (62,2%), dores de cabe√ßa foram mais prevalentes (48,9%), cansar com facilidade (42,2%), perda de interesse pelas coisas (20%), sofrimento ps√≠quico prevalente em docentes h√° mais de 4 anos de trabalho. Destacamos que em virtude da import√Ęncia da tem√°tica h√° uma escassez de trabalhos cient√≠ficos que exploram esse assunto. Assim, torna-se necess√°rio que se fa√ßam pesquisas que compreendam os professores j√° que eles apresentam suscetibilidade para o desenvolvimento de transtornos psicossom√°ticos.O ambiente acad√™mico n√£o √© estranho ao sofrimento. Sabe-se que as doen√ßas mentais est√£o presentes em quase todas as atividades e contextos em que o ser humano atua. Assim, no contexto universit√°rio, a grande maioria do corpo docente, vivencia um elevado grau de estresse acad√™mico. O objetivo deste estudo foi avaliar os fen√īmenos psicossom√°ticos e seus sinais nos professores universit√°rios. Trata-se de um estudo observacional transversal, descritivo de abordagem quantitativa, constitu√≠do por 45 dos cursos de ensino superior de uma universidade privada em S√£o Lu√≠s do Maranh√£o. O instrumento de coleta de dados foi um question√°rio com dados sociodemogr√°ficos e escala de teste: SQR 20. Os resultados apontaram que a maioria do sexo feminino (59,1%),com idades entre 26 a 50 anos ,casadas (52,3%), com renda entre ¬†cinco ou mais sal√°rios m√≠nimos (59,1%), maior parte com titula√ß√£o m√°xima o mestrado (50%), atuantes na √°rea da sa√ļde (50%), humor depressivo , nervoso foi o mais frequente (62,2%), dores de cabe√ßa foram mais prevalentes (48,9%), cansar com facilidade (42,2%), perda de interesse pelas coisas (20%), sofrimento ps√≠quico prevalente em docentes h√° mais de 4 anos de trabalho. Destacamos que em virtude da import√Ęncia da tem√°tica h√° uma escassez de trabalhos cient√≠ficos que exploram esse assunto. Assim, torna-se necess√°rio que se fa√ßam pesquisas que compreendam os professores j√° que eles apresentam suscetibilidade para o desenvolvimento de transtornos psicossom√°ticos

    N√ćVEIS DE ANSIEDADE E DEPRESS√ÉO: A PR√ĀTICA DOCENTE E O ADOECIMENTO PS√ćQUICO

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    Anxiety and depression are the most well-known mental disorders that affect the population worldwide as a whole, and these diseases, which have been generating one of the highest rates of disability, in addition to signs and symptoms such as fear and suffering in advance, tanties, changes in breathing, tremors; while depression is marked by feelings of anguish, dread, change in appetite and sleep, and loss of interest. This research aimed to promote the investigation of the factors that trigger the development of psychic illness in university professors. This is a cross-sectional, descriptive, quantitative observational study, which had as the instruments used a questionnaire of sociodemographic data and the Depression, Anxiety and Stress Scale - Short Form (DASS-21) test, the population consisted of professors from a private university in northeastern Brazil. The results showed that the rate of anxiety and depression in an age group between 26 and 36 years or 37 to 50 years were lower than in the literature, thus representing that the incidence of these diseases is being earlier; another issue is that the teachers who had higher income were the same ones who presented anxiety and depression to some degree. It is concluded that the risk of mental illness in teachers is very found and recurrent, due to the stressors present in their workplace; being, therefore, something that should be noticed by educational institutions.La ansiedad y la depresi√≥n son los trastornos mentales m√°s conocidos que afectan a la poblaci√≥n mundial en su conjunto, y estas enfermedades, que han estado generando una de las tasas m√°s altas de discapacidad, adem√°s de signos y s√≠ntomas como miedo y sufrimiento de antemano, tanties, cambios en la respiraci√≥n, temblores; mientras que la depresi√≥n est√° marcada por sentimientos de angustia, temor, cambio en el apetito y el sue√Īo, y p√©rdida de inter√©s. Esta investigaci√≥n tuvo como objetivo promover la investigaci√≥n de los factores que desencadenan el desarrollo de la enfermedad ps√≠quica en profesores universitarios. Se trata de un estudio observacional transversal, descriptivo, cuantitativo, que tuvo como instrumentos utilizados un cuestionario de datos sociodemogr√°ficos y la prueba Escala de Depresi√≥n, Ansiedad y Estr√©s - Forma Corta (DASS-21), la poblaci√≥n consisti√≥ en profesores de una universidad privada en el noreste de Brasil. Los resultados mostraron que la tasa de ansiedad y depresi√≥n en un grupo de edad entre 26 y 36 a√Īos o 37 a 50 a√Īos fue menor que en la literatura, lo que representa que la incidencia de estas enfermedades est√° siendo m√°s temprana; Otro problema es que los maestros que ten√≠an mayores ingresos eran los mismos que presentaban ansiedad y depresi√≥n en alg√ļn grado. Se concluye que el riesgo de enfermedad mental en los maestros es muy encontrado y recurrente, debido a los factores estresantes presentes en su lugar de trabajo; siendo, por lo tanto, algo que debe ser notado por las instituciones educativas.A ansiedade e a depress√£o s√£o os transtornos mentais mais conhecidos e que afetam mundialmente a popula√ß√£o como um todo, e doen√ßas essas, que v√™m gerando um dos maiores √≠ndices de incapacita√ß√£o, al√©m de sinais e sintomas como medo e sofrimento por anteced√™ncia, taquicardia, altera√ß√£o na respira√ß√£o, tremores; enquanto a depress√£o √© marcada por sentimento de ang√ļstia, pavor, mudan√ßa no apetite e no sono e perda de interesse. Esta pesquisa teve como objetivo promover a investiga√ß√£o dos fatores que desencadeiam o desenvolvimento de adoecimento ps√≠quico em professores universit√°rios. Trata-se de um estudo observacional transversal, descritivo, de abordagem quantitativa, que teve como os instrumentos utilizados um question√°rio de dados sociodemogr√°ficos e o teste Depression, Anxiety and Stress Scale - Short Form (DASS-21), a popula√ß√£o se constituiu de docentes de uma universidade privada do nordeste do Brasil. Os resultados evidenciaram que o √≠ndice de ansiedade e depress√£o em uma faixa et√°ria entre 26 e 36 anos ou de 37 a 50 anos foram menores do que na literatura outrora encontrava, representando assim, que a incid√™ncia dessas doen√ßas est√° sendo de forma mais precoce; outra quest√£o √© que os docentes que apresentavam maior renda s√£o os mesmos que apresentaram ansiedade e depress√£o em algum grau. Conclui-se que o risco de adoecimento mental em docentes √© muito encontrado e recorrente, devido aos fatores estressores presentes em seu lugar de trabalho; sendo, portanto, algo que deve ser notado pelas institui√ß√Ķes de ensino.A ansiedade e a depress√£o s√£o os transtornos mentais mais conhecidos e que afetam mundialmente a popula√ß√£o como um todo, e doen√ßas essas, que v√™m gerando um dos maiores √≠ndices de incapacita√ß√£o, al√©m de sinais e sintomas como medo e sofrimento por anteced√™ncia, taquicardia, altera√ß√£o na respira√ß√£o, tremores; enquanto a depress√£o √© marcada por sentimento de ang√ļstia, pavor, mudan√ßa no apetite e no sono e perda de interesse. Esta pesquisa teve como objetivo promover a investiga√ß√£o dos fatores que desencadeiam o desenvolvimento de adoecimento ps√≠quico em professores universit√°rios. Trata-se de um estudo observacional transversal, descritivo, de abordagem quantitativa, que teve como os instrumentos utilizados um question√°rio de dados sociodemogr√°ficos e o teste Depression, Anxiety and Stress Scale - Short Form (DASS-21), a popula√ß√£o se constituiu de docentes de uma universidade privada do nordeste do Brasil. Os resultados evidenciaram que o √≠ndice de ansiedade e depress√£o em uma faixa et√°ria entre 26 e 36 anos ou de 37 a 50 anos foram menores do que na literatura outrora encontrava, representando assim, que a incid√™ncia dessas doen√ßas est√° sendo de forma mais precoce; outra quest√£o √© que os docentes que apresentavam maior renda s√£o os mesmos que apresentaram ansiedade e depress√£o em algum grau. Conclui-se que o risco de adoecimento mental em docentes √© muito encontrado e recorrente, devido aos fatores estressores presentes em seu lugar de trabalho; sendo, portanto, algo que deve ser notado pelas institui√ß√Ķes de ensino

    ORALIDADE E FORMA√á√ÉO PROFISSIONAL DOCENTE: CONFIGURA√á√ēES DO G√äNERO ORAL PROVA DID√ĀTICA

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    In this paper, we analyze the configurations of the oral genre didactic-test in the context of a public contest for the teaching career. We seek fundamentals about the importance of teacher education strongly related to the field of work, which involves a series of professional knowledge and practices. In addition, we are based on the concept of textual genre, from different theoretical perspectives, which cover pragmatic, historical and ideological issues in the analysis, which allowed us to unveil still fragile topics in public notices for such a career. In this exploratory study, we used six public notices, in addition to the authors' experiences - in the role of candidates and members of the examining committee; with these data, we featured the most common topics of this practice of orality. The data were organized into eight items, which reveal the settings of the genre: the context of circulation, the interlocutors and roles, other genres involved, the simulation, the typical forms of interaction, the didactic resources, the content and the non-linguistic aspects of this typical oral genre. The study allows us to better visualize fundamental elements for the performance of the teacher-candidate, which also strengthens the discourse in favor of learning the teacher‚Äôs m√©tier gender in their professionalization. &nbsp;Neste trabalho, analisamos as configura√ß√Ķes do g√™nero oral prova did√°tica em contexto de concurso para a carreira de magist√©rio. Buscamos fundamentos acerca da import√Ęncia da forma√ß√£o de professores fortemente relacionada ao campo do trabalho, que envolve uma s√©rie de conhecimentos e pr√°ticas profissionais. Al√©m disso, baseamo-nos no conceito de g√™nero textual, a partir de diferentes perspectivas te√≥ricas, que abarcam quest√Ķes pragm√°ticas, hist√≥ricas e ideol√≥gicas na an√°lise, o que nos permitiu descortinar t√≥picos ainda fr√°geis em editais de concurso para tal carreira. Neste estudo explorat√≥rio, lan√ßamos m√£o de seis editais de concurso, al√©m de experi√™ncias dos autores - no papel de candidatas/os e integrantes de bancas; com esses dados, caracterizamos os t√≥picos mais comuns desta pr√°tica de oralidade. Os dados foram organizados em oito itens, que revelam as configura√ß√Ķes do g√™nero: o contexto de circula√ß√£o, os interlocutores e pap√©is, outros g√™neros envolvidos, a simula√ß√£o, as formas t√≠picas de intera√ß√£o, os recursos did√°ticos, o conte√ļdo e os aspectos n√£o lingu√≠sticos desse t√≠pico g√™nero oral. O estudo permite melhor visualizar elementos fundamentais para atua√ß√£o do professor-candidato, o que tamb√©m fortalece o discurso em prol da aprendizagem dos g√™neros do m√©tier docente na sua profissionaliza√ß√£o

    Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial

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    Background Sparsentan, a novel, non-immunosuppressive, single-molecule, dual endothelin angiotensin receptor antagonist, significantly reduced proteinuria versus irbesartan, an angiotensin II receptor blocker, at 36 weeks (primary endpoint) in patients with immunoglobulin A nephropathy in the phase 3 PROTECT trial's previously reported interim analysis. Here, we report kidney function and outcomes over 110 weeks from the double-blind final analysis. Methods PROTECT, a double-blind, randomised, active-controlled, phase 3 study, was done across 134 clinical practice sites in 18 countries throughout the Americas, Asia, and Europe. Patients aged 18 years or older with biopsy-proven primary IgA nephropathy and proteinuria of at least 1¬∑0 g per day despite maximised renin‚Äďangiotensin system inhibition for at least 12 weeks were randomly assigned (1:1) to receive sparsentan (target dose 400 mg oral sparsentan once daily) or irbesartan (target dose 300 mg oral irbesartan once daily) based on a permuted-block randomisation method. The primary endpoint was proteinuria change between treatment groups at 36 weeks. Secondary endpoints included rate of change (slope) of the estimated glomerular filtration rate (eGFR), changes in proteinuria, a composite of kidney failure (confirmed 40% eGFR reduction, end-stage kidney disease, or all-cause mortality), and safety and tolerability up to 110 weeks from randomisation. Secondary efficacy outcomes were assessed in the full analysis set and safety was assessed in the safety set, both of which were defined as all patients who were randomly assigned and received at least one dose of randomly assigned study drug. This trial is registered with ClinicalTrials.gov, NCT03762850. Findings Between Dec 20, 2018, and May 26, 2021, 203 patients were randomly assigned to the sparsentan group and 203 to the irbesartan group. One patient from each group did not receive the study drug and was excluded from the efficacy and safety analyses (282 [70%] of 404 included patients were male and 272 [67%] were White) . Patients in the sparsentan group had a slower rate of eGFR decline than those in the irbesartan group. eGFR chronic 2-year slope (weeks 6‚Äď110) was ‚ąí2¬∑7 mL/min per 1¬∑73 m2 per year versus ‚ąí3¬∑8 mL/min per 1¬∑73 m2 per year (difference 1¬∑1 mL/min per 1¬∑73 m2 per year, 95% CI 0¬∑1 to 2¬∑1; p=0¬∑037); total 2-year slope (day 1‚Äďweek 110) was ‚ąí2¬∑9 mL/min per 1¬∑73 m2 per year versus ‚ąí3¬∑9 mL/min per 1¬∑73 m2 per year (difference 1¬∑0 mL/min per 1¬∑73 m2 per year, 95% CI ‚ąí0¬∑03 to 1¬∑94; p=0¬∑058). The significant reduction in proteinuria at 36 weeks with sparsentan was maintained throughout the study period; at 110 weeks, proteinuria, as determined by the change from baseline in urine protein-to-creatinine ratio, was 40% lower in the sparsentan group than in the irbesartan group (‚ąí42¬∑8%, 95% CI ‚ąí49¬∑8 to ‚ąí35¬∑0, with sparsentan versus ‚ąí4¬∑4%, ‚ąí15¬∑8 to 8¬∑7, with irbesartan; geometric least-squares mean ratio 0¬∑60, 95% CI 0¬∑50 to 0¬∑72). The composite kidney failure endpoint was reached by 18 (9%) of 202 patients in the sparsentan group versus 26 (13%) of 202 patients in the irbesartan group (relative risk 0¬∑7, 95% CI 0¬∑4 to 1¬∑2). Treatment-emergent adverse events were well balanced between sparsentan and irbesartan, with no new safety signals. Interpretation Over 110 weeks, treatment with sparsentan versus maximally titrated irbesartan in patients with IgA nephropathy resulted in significant reductions in proteinuria and preservation of kidney function.</p

    Visitors' satisfaction in natural areas: the case of Vinhais biological park

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    Satisfaction is a widely studied issue in tourism as it provides an understanding of the performance of a tourism destination's offer, highlighting the most important features considered by tourists. The growth in tourism demand in natural areas also makes it an important factor in identifying visitor satisfaction, as sustainable planning of these areas may also rely on knowing the opinion of their visitors. In this context, this study aimed to determine the visitors¬ī satisfaction with Vinhais Biological Park, located in the northeast of Portugal, during the summer of 2022. A questionnaire consisting of 8 closed-ended questions to identify the socio-demographic profile and overall satisfaction was applied during July and August 2022. Therefore, 251 valid questionnaires were considered for the quantitative data analysis and a final sampling error of 6.13% was assumed. A descriptive statistical analysis was performed to identify the socio-demographic profile and the satisfaction with the resources offered. Four hypotheses were formulated to test the association between socio-demographic profile (age group, gender, nationality, and education level) and overall satisfaction. The Ōá2 test was used to test the hypotheses assuming a 5% significance level. The main findings showed that the socio-demographic profile of the sample is predominantly male (54.6%), aged between 11 and 40 years (77.6%), of Portuguese nationality (71.3%) and with higher education level (48.6%). Concerning the visit motivation, 61.4% went to the park after visiting the city of Vinhais or the region and nearly half (47%) of the respondents were satisfied. The results of Ōá2 test revealed no significant association between the socio-demographic profile and overall satisfaction, meaning that none of the hypotheses was supported. Considering the number of visitors received in the park annually, this study's sample can be regarded as a limitation, making the understanding of satisfaction limited to the period of analysis and at a period when the impact of COVID-19 is noticeable. Finally, for future studies, a comparative analysis with other natural parks, both Portuguese and Spanish, is suggested for better monitoring of visitor satisfaction.This project is being carried out within the scope of the DuraDOURO - El Duero como recurso perdurable del paisaje y el territorio de la frontera, 0785_DURADOURO_2_E, financed by FEDER, through the POCTEP. The authors are also grateful to the UNIAG, R&D unit funded by the FCT ‚Äď Portuguese Foundation for the Development of Science and Technology, Ministry of Science, Technology and Higher Education. ‚ÄúProject Code Reference: UIDB/04752/2020 e UIDP/04752/2020‚ÄĚ.info:eu-repo/semantics/publishedVersio

    Increased interregional virus exchange and nucleotide diversity outline the expansion of chikungunya virus in Brazil

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    Abstract The emergence and reemergence of mosquito-borne diseases in Brazil such as yellow fever, zika, chikungunya, and dengue have had serious impacts on public health. Concerns have been raised due to the rapid dissemination of the chikungunya virus across the country since its first detection in 2014 in Northeast Brazil. In this work, we carried out on-site training activities in genomic surveillance in partnership with the National Network of Public Health Laboratories that have led to the generation of 422 chikungunya virus genomes from 12 Brazilian states over the past two years (2021‚Äď2022), a period that has seen more than 312 thousand chikungunya fever cases reported in the country. These genomes increased the amount of available data and allowed a more comprehensive characterization of the dispersal dynamics of the chikungunya virus East-Central-South-African lineage in Brazil. Tree branching patterns revealed the emergence and expansion of two distinct subclades. Phylogeographic analysis indicated that the northeast region has been the leading hub of virus spread towards other regions. Increased frequency of C‚ÄČ>‚ÄČT transitions among the new genomes suggested that host restriction factors from the immune system such as ADAR and AID/APOBEC deaminases might be driving the genetic diversity of the chikungunya virus in Brazil

    Práticas tradutórias em TAVA: a associação de Libras, LSE, AD e audiolegendagem no vídeo de divulgação do XIV SEPESQ

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    Este artigo se constitui no relato de uma experi√™ncia formativa em Tradu√ß√£o Audiovisual Acess√≠vel (TAVA). O grupo de pesquisa Tradu√ß√£o e Acessibilidade (TrAce) produziu a legendagem para Surdos e ensurdecidos (LSE), a audiodescri√ß√£o (AD) e a audiolegendagem do v√≠deo de divulga√ß√£o do XIV Semin√°rio de Pesquisa Estudantil em Letras (XIV SEPESQ), evento anual do Instituto de Letras da Universidade Federal da Bahia (ILUFBA). Durante o projeto, no entanto, o grupo enfrentou v√°rios desafios, como, por exemplo, a tradu√ß√£o da Libras para o portugu√™s, a AD de sinais com movimento, a sincroniza√ß√£o das legendas com a sinaliza√ß√£o em Libras, entre outros. A fim de superar esses obst√°culos, recorreu-se a diferentes estrat√©gias, incluindo a cria√ß√£o da AD a partir dos cinco par√Ęmetros da Libras, a segmenta√ß√£o cuidadosa das legendas e a utiliza√ß√£o de v√°rios recursos de edi√ß√£o.¬†This article is the report of a formative experience in Accessible Audiovisual Translation (AAVT). The research group Tradu√ß√£o e Acessibilidade (TrAce) produced the subtitles for the Deaf and hard of hearing (SDH), the audio description (AD) and the audio subtitling of the video publicizing the XIV Semin√°rio de Pesquisa Estudantil em Letras (XIV SEPESQ), an annual event of the Instituto de Letras of the Universidade Federal da Bahia (ILUFBA). During the project, however, the group faced several challenges, such as the translation of Brazilian sign language (Libras) into Portuguese, the AD of signs with movement and the synchronization of SDH with the signaling in Libras. In order to overcome these obstacles, different strategies were used, including the employment of the five parameters of Libras as a basis for the AD, the careful segmentation of the subtitles and the use of various editing resources

    (RE)pensando a Formação Docente: o que o Ensino Remoto Emergencial Diz sobre a Formação do professor?

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    Emergency remote education was created to adapt formal education practices. This action, understood as provisional, revealed movements and emergencies that are beyond the context of the new Coronavirus pandemic. In this article, the methodology of systematic literature review was used to carry out a survey on the challenges presented in remote emergency education and to draw reflections on the necessary characteristics of teachers in the world permeated by cyberculture. The results pointed out that the challenges faced by teachers are independent of level of education: lack of training to work with technologies; apathetic students and without access to the Internet; teachers overloaded with multiple activities, are some of them. We conclude by pointing out the need for a teacher training.¬† ¬† Keywords: Teaching training. Educational technologies. Remote education.O ensino remoto emergencial foi criado para adaptar as pr√°ticas da educa√ß√£o formal. Esta a√ß√£o, entendida como provis√≥ria, desvelou movimentos e urg√™ncias que est√£o para al√©m do contexto de pandemia do novo Coronav√≠rus. Neste artigo, foi utilizada a metodologia de revis√£o sistem√°tica de literatura para realizar um levantamento sobre os desafios apresentados no ensino emergencial remoto e tra√ßar reflex√Ķes sobre as caracter√≠sticas necess√°rias nos docentes no mundo permeado pela cibercultura. Os resultados apontaram que os desafios enfrentados pelos docentes independem de n√≠vel de ensino: falta de forma√ß√£o para atuar com tecnologias; alunos ap√°ticos e sem acesso √† internet; docentes sobrecarregados com m√ļltiplas atividades, s√£o alguns deles. Conclui-se apontando a necessidade de uma forma√ß√£o docente que abarque distintas e novas compet√™ncias e habilidades necess√°rias para sua atua√ß√£o no contexto atual de ensino remoto e no ensino h√≠brido em um cen√°rio p√≥s-pandemia. ¬† Palavras-chave: Forma√ß√£o docente. Tecnologias educativas. Ensino remoto. ¬†
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