13 research outputs found

    Summary of the adhesion of PLGA spheres from flow of buffer, plasma and blood to an activated endothelial cell monolayer.

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    <p>(A) A depiction of particle margination in buffer, plasma and blood flow. Binding density after 5 min of flow for (B) 5 µm, (C) 1.4 µm and (D) 300 nm sLe<sup>a</sup>-coated pLGA particles to activated HUVEC monolayer from laminar buffer, plasma, or whole blood at 200 s<sup>−1</sup>. Particle concentration  = 5e5 particles/mL for 5 and 1.4 µm data and 1e6 particles/mL for the 330 nm particles. sLe<sup>a</sup> density  = 1,700+/−100 sites/µm<sup>2</sup> (SEM) surface for 5 µm, 1500+/−100 sites/µm<sup>2</sup> (SEM) for 1.4 µm and 9,000+/−400 sites/µm<sup>2</sup> (SEM) for 330 nm particles. N = 3 distinct donors (donors A, B and C).</p

    Relationship between age and sustained virologic response (SVR).

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    <p>Short vertical lines indicate the number of patients with SVR (black lines) and no SVR (grey lines). Open circles represent probability of SVR according to the GAM analysis. Closed circles represent empirical probability for midpoints of deciles.</p

    Relationship between platelet count and sustained virologic response (SVR).

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    <p>Short vertical lines indicate the number of patients with SVR (black lines) and no SVR (grey lines). Open circles represent probability of SVR according to the GAM analysis. Closed circles represent empirical probability for midpoints of deciles.</p
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