811 research outputs found

    Using Personality Traits To Predict Boundary Management Strategies

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    This research attempted to answer the question if it possible to predict an individual’s boundary management strategies by using their personality traits. Participants (N = 99) were recruited on the website LinkedIn to answer a survey that included questions about their personality traits, their workplace culture around boundary management, the type of boundary management strategy they preferred to use, and the strategies they used. The traits Openness to Experience, Conscientiousness, and Agreeableness were found to be significant personality traits to use when predicting preferred boundary management strategies with a moderately strong relationship to preferring Segmentation boundary management strategies. Contrary to previous research, my data suggest that Neuroticism has a weak relationship with preference for Segmentation boundary management. It was also found that segmentation preferences and workplace segmentation culture showed no significant mediation or moderating effects. Finally, the data suggest that a workplace’s boundary management culture affects participants’ use of boundary management strategies

    TITUS: Visualization of Neutrino Events in Liquid Argon Time Projection Chambers

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    The amount and complexity of data recorded by high energy physics experiments are rapidly growing, and with these grow the difficulties in visualizing such data. To study the physics of neutrinos, a type of elementary particles, scientists use liquid argon time projection chamber (LArTPC) detectors among other technologies. LArTPCs have a very high spatial resolution and resolve many of the elementary particles that come out of a neutrino interacting within the argon in the detector. Visualizing these neutrino interactions is of fundamental importance to understand the properties of neutrinos, but also monitor and check on the detector conditions and operations. From these ideas, we have developed TITUS, an event display that shows images recorded by these neutrino detectors. TITUS is a software that reads data coming from LArTPC detectors (as well as corresponding simulation) and allows users to explore such data in multiple ways. TITUS is flexible to enable fast prototyping and customization.Comment: 8 pages, 4 figure

    Partnering with healthcare: The experiences of consumer representatives

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    The importance of consumer advocacy in person-centred healthcare service planning and delivery is growing. In Australia, the role of the Consumer Representative (known internationally as Patient and Family Advisors ) is to advocate for patients and their families\u27 needs to improve service planning, healthcare design, and service evaluation. As the role of consumer representatives evolves and matures within the healthcare setting, it is crucial to comprehend their experiences and identify key insights to support and enhance their role within healthcare organizations. To achieve this, a focus group of four Consumer Representatives was conducted and their views were compiled into a single commentary. Our findings suggest that Consumers Representatives are driven by a desire to assist others, but they may feel dissatisfied if their role is perceived as tokenistic or lacks meaningful engagement. Consumer Representatives suggested various ways to improve consumer participation, including role clarification, meeting facilitation, and the development of supportive consumer networks. Experience Framework This article is associated with the Patient, Family & Community Engagement lens of The Beryl Institute Experience Framework (https://www.theberylinstitute.org/ExperienceFramework). Access other PXJ articles related to this lens. Access other resources related to this lens

    Improving swallow function in progressive dysphagia associated with Huntington's Disease

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    This study examined the effects of oral-motor, respiratory, and pharyngeal strengthening exercises on dysphagia in individuals with Huntington's disease. In a pre-test, post-test design, five participants voluntarily implemented the aforementioned exercises daily for a four-week period. The function of the oral-motor, pharyngeal, and respiratory structures was measured both at baseline and at study completion. In addition, participants provided a self-rating of their swallow function prior to and subsequent to implementation of the selected exercises. Swallowing function was also examined through an informal bedside evaluation and documented by a clinician at baseline and at conclusion of the study. A statistically significant improvement in the function of the oral-motor, pharyngeal, and respiratory structures was noted. No statistically significant improvement was noted in the participants self-rating of their swallow function; however, four of the five participants appeared to maintain and/or improve swallow function as reported by the individual and as noted on the informal bedside evaluation by the clinician. In conclusion, the null hypothesis could not be rejected. It could not be concluded that the selected exercises improved dysphagia based upon the participants self-rating of swallow function. However, as a statistically significant improvement in oral-motor function was realized, the findings raise concerns as to the sensitivity of swallow-screening measures for individuals with Huntington's disease. It is critical that an objective swallow-screening measure be developed sensitive to the ramifications of Huntington's disease and various other disorders affecting cognition.Department of Communication Sciences and Disorder

    Blood and Marrow Transplant Clinical Trials Network Toxicity Committee Consensus Summary: Thrombotic Microangiopathy after Hematopoietic Stem Cell Transplantation

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    AbstractThe syndrome of microangiopathic hemolysis associated with renal failure, neurologic impairment, or both is a recognized complication of hematopoietic stem cell transplantation. This entity is often called hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP), yet it is clear that the pathophysiology of transplant-associated HUS/TTP is different from that of classic HUS or TTP. Furthermore, the incidence of this syndrome varies from 0.5% to 76% in different transplant series, primarily because of the lack of a uniform definition. The toxicity committee of the Blood and Marrow Transplant Clinical Trials Network has reviewed the current literature on transplant-related HUS/TTP and recommends that it be henceforth renamed posttransplantation thrombotic microangiopathy (TMA). An operational definition for TMA based on the presence of microangiopathic hemolysis and renal and/or neurologic dysfunction is proposed. The primary intervention after diagnosis of TMA should be withdrawal of calcineurin inhibitors. Plasma exchange, although frequently used in this condition, has not been proven to be effective. In the absence of definitive trials, plasma exchange cannot be considered a standard of care for TMA. It is hoped that these positions will improve the identification and reporting of this devastating complication after hematopoietic stem cell transplantation and facilitate future clinical studies for its prevention and treatment

    Accurate model annotation of a near-atomic resolution cryo-EM map

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    Electron cryomicroscopy (cryo-EM) has been used to determine the atomic coordinates (models) from density maps of biological assemblies. These models can be assessed by their overall fit to the experimental data and stereochemical information. However, these models do not annotate the actual density values of the atoms nor their positional uncertainty. Here, we introduce a computational procedure to derive an atomic model from a cryo- EM map with annotated metadata. The accuracy of such a model is validated by a faithful replication of the experimental cryo-EM map computed using the coordinates and associated metadata. The functional interpretation of any structural features in the model and its utilization for future studies can be made in the context of its measure of uncertainty. We applied this protocol to the 3.3-Ă… map of the mature P22 bacteriophage capsid, a large and complex macromolecular assembly.With this protocol, we identify and annotate previously undescribed molecular interactions between capsid subunits that are crucial to maintain stability in the absence of cementing proteins or cross-linking, as occur in other bacteriophages.National Institutes of Health (U.S.) (Grant P41GM103832)National Institutes of Health (U.S.) (Grant R01GM079429)National Institutes of Health (U.S.) (Grant PN2EY016525)National Institutes of Health (U.S.) (Grant P01GM063210)Robert A. Welch Foundation (Grant Q1242
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