Scattering Lens Resolves sub-100 nm Structures with Visible Light

The smallest structures that conventional lenses are able to optically resolve are of the order of 200 nm. We introduce a new type of lens that exploits multiple scattering of light to generate a scanning nano-sized optical focus. With an experimental realization of this lens in gallium phosphide we have succeeded to image gold nanoparticles at 97 nm optical resolution. Our work is the first lens that provides a resolution in the nanometer regime at visible wavelengths.Comment: 4 pages, 3 figure

Entropic force in black hole binaries and its Newtonian limits

We give an exact solution for the static force between two black holes at the turning points in their binary motion. The results are derived by Gibbs' principle and the Bekenstein-Hawking entropy applied to the apparent horizon surfaces in time-symmetric initial data. New power laws are derived for the entropy jump in mergers, while Newton's law is shown to derive from a new adiabatic variational principle for the Hilbert action in the presence of apparent horizon surfaces. In this approach, entropy is strictly monotonic such that gravity is attractive for all separations including mergers, and the Bekenstein entropy bound is satisfied also at arbitrarily large separations, where gravity reduces to Newton's law. The latter is generalized to point particles in the Newtonian limit by application of Gibbs' principle to world-lines crossing light cones.Comment: Accepted for publication in Phys. Rev.

Peripheral neuropathy induced by combination chemotherapy of docetaxel and cisplatin.

Docetaxel, a new semisynthetic taxoid that has demonstrated promising activity as an antineoplastic agent, was administered in combination with cisplatin to 63 patients in a dose-escalating study. As both drugs were known to be potentially neurotoxic, peripheral neurotoxicity was prospectively assessed in detail. Neuropathy was evaluated by clinical sum-score for signs and symptoms and by measurement of the vibration perception threshold (VPT). The severity of neuropathy was graded according to the National Cancer Institute's 'Common Toxicity Criteria'. The docetaxel-cisplatin combination chemotherapy induced a predominantly sensory neuropathy in 29 (53%) out of 55 evaluable patients. At cumulative doses of both cisplatin and docetaxel above 200 mg m(-2), 26 (74%) out of 35 patients developed a neuropathy which was mild in 15, moderate in ten and severe in one patient. Significant correlations were present between both the cumulative dose of docetaxel and cisplatin and the post-treatment sum-score of neuropathy (P < 0.01) as well as the post-treatment VPT (P < 0.01). The neurotoxic effects of this combination were more severe than either cisplatin or docetaxel as single agent at similar doses

Measurement of the ΔS=-ΔQ Amplitude from K_(e3)^0 Decay

We have measured the time distribution of the π^+e^-ν and π^-e^+ν modes from initial K^0's in a spark-chamber experiment performed at the Bevatron. From 1079 events between 0.2 and 7 K_S^0 lifetime, we find ReX=-0.069±0.036, ImX=+0.108_(-0.074)^(+0.092). This result is consistent with X=0 (relative probability = 0.25), but more than 4 standard deviations from the existing world average, +0.14 -0.13i

Gravitational radiation from gamma-ray bursts as observational opportunities for LIGO and VIRGO

Gamma-ray bursts are believed to originate in core-collapse of massive stars. This produces an active nucleus containing a rapidly rotating Kerr black hole surrounded by a uniformly magnetized torus represented by two counter-oriented current rings. We quantify black hole spin-interactions with the torus and charged particles along open magnetic flux-tubes subtended by the event horizon. A major output of Egw=4e53 erg is radiated in gravitational waves of frequency fgw=500 Hz by a quadrupole mass-moment in the torus. Consistent with GRB-SNe, we find (i) Ts=90s (tens of s, Kouveliotou et al. 1993), (ii) aspherical SNe of kinetic energy Esn=2e51 erg (2e51 erg in SN1998bw, Hoeflich et al. 1999) and (iii) GRB-energies Egamma=2e50 erg (3e50erg in Frail et al. 2001). GRB-SNe occur perhaps about once a year within D=100Mpc. Correlating LIGO/Virgo detectors enables searches for nearby events and their spectral closure density 6e-9 around 250Hz in the stochastic background radiation in gravitational waves. At current sensitivity, LIGO-Hanford may place an upper bound around 150MSolar in GRB030329. Detection of Egw thus provides a method for identifying Kerr black holes by calorimetry.Comment: to appear in PRD, 49

Theory and astrophysical consequences of a magnetized torus around a rapidly rotating black hole

(Abbrev.) We analyze the topology, lifetime, and emissions of a torus around a black hole formed in hypernovae and black hole-neutron star coalescence. The torus is ab initio uniformly magnetized, represented by two counter oriented current-rings, and develops a state of suspended accretion against a "magnetic wall" around the black hole. Magnetic stability of the torus gives rise to a new fundamental limit EB/Ek<0.1 for the ratio of poloidal magnetic field energy-to-kinetic energy. The lifetime of rapid spin of the black hole is effectively defined by the timescale of dissipation of black hole-spin energy in the horizon, and satisfies T= 40s (MH/7MSun)(R/6MH)^4(0.03MH/MT) for a black hole of mass MH surrounded by a torus of mass MT and radius R. The torus converts a major fraction Egw/Erot=0.1 into gravitational radiation through a finite number of multipole mass-moments, and a smaller fraction into MeV neutrinos and baryon-rich winds. At a source distance of 100Mpc, these emissions over N=2e4 periods give rise to a characteristic strain amplitude \sqrt{N}hchar=6e-21. We argue that torus winds create an open magnetic flux-tube on the black hole, which carries a minor and standard fraction Ej/Erot=1e-3 in baryon-poor outflows to infinity. We identify this baryon poor output of tens of seconds with GRBs with contemporaneous and strongly correlated emissions in gravitational radiation, conceivably at multiple frequencies. Ultimately, this leaves a black hole binary surrounded by a supernova remnant.Comment: To appear in ApJ (44p

On the detectability of gravitational waves background produced by gamma ray bursts

In this paper we discuss a new strategy for the detection of gravitational radiation likely emitted by cosmological gamma ray burst. Robust and conservative estimates lead to the conclusion that the uncorrelated superimposition of bursts of gravitational waves can be detected by interferometric detectors like VIRGO or LIGO. The expected signal is predicted to carry two very distinctive signatures: the cosmological dipole anisotropy and a characteristic time scale in the auto correlation spectrum, which might be exploited, perhaps with ad hoc modifications and/or upgrading of the planned experiments, to confirm the non-instrumental origin of the signal.Comment: 9 pages, 2 figures, LATEX2e, Accepted for pubblications as a Letter to the Editor in Journal of Physics G: Nuclear and Particle Physic

Soil pathogen-aphid interactions under differences in soil organic matter and mineral fertilizer

There is increasing evidence showing that microbes can influence plant-insect interactions. In addition, various studies have shown that aboveground pathogens can alter the interactions between plants and insects. However, little is known about the role of soil-borne pathogens in plant-insect interactions. It is also not known how environmental conditions, that steer the performance of soil-borne pathogens, might influence these microbe-plant-insect interactions. Here, we studied effects of the soil-borne pathogen Rhizoctonia solani on aphids (Sitobion avenae) using wheat (Triticum aestivum) as a host. In a greenhouse experiment, we tested how different levels of soil organic matter (SOM) and fertilizer addition influence the interactions between plants and aphids. To examine the influence of the existing soil microbiome on the pathogen effects, we used both unsterilized field soil and sterilized field soil. In unsterilized soil with low SOM content, R. solani addition had a negative effect on aphid biomass, whereas it enhanced aphid biomass in soil with high SOM content. In sterilized soil, however, aphid biomass was enhanced by R. solani addition and by high SOM content. Plant biomass was enhanced by fertilizer addition, but only when SOM content was low, or in the absence of R. solani. We conclude that belowground pathogens influence aphid performance and that the effect of soil pathogens on aphids can be more positive in the absence of a soil microbiome. This implies that experiments studying the effect of pathogens under sterile conditions might not represent realistic interactions. Moreover, pathogen-plant-aphid interactions can be more positive for aphids under high SOM conditions. We recommend that soil conditions should be taken into account in the study of microbe-plant-insect interactions